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Paul McCain Presentation
Paul McCain Presentation

... Tom70 after CCCP treatment of Parkin-expressing cells after approximately one hour VDAC1 (solute transport), Fis1 (mitochondrial fission), Bak (cellular apoptosis) and Tom20 (protein import) also reduced but over a longer time period Intermembrane and matrix proteins of mitochondria showed no signif ...
pCas-Guide System Validation
pCas-Guide System Validation

1

HSP60



Heat shock proteins are generally responsible for preventing damage to proteins in response to high levels of heat. Heat shock proteins are classified into six major families based on their molecular mass: small HSPs, HSP40, HSP60, HSP70, HSP90, and HSP110HSP60 Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. Interacts with HRAS. Interacts with HBV protein X and HTLV-1 protein p40tax. Belongs to the chaperonin (HSP60) family. Note: This description may include information from UniProtKB. Alternate Names:
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