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25. Organ of balance and hearing
25. Organ of balance and hearing

... Otoliths are located within the matrix of the macula Changing head position produces a change of pressure on the otolith-weighted matrix, stimulating the hair cells that stimulate the receptors of the vestibular nerve Vestibular nerve fibers conduct impulses to the brain and sense head position and ...
GustOlf9
GustOlf9

... B. 1° olfactory neurons in nasal mucosa (olfactory mucosa) in superior nasal concha contains bipolar neurons which are chemosensitive  small fasciculus  cribiform plate of ethmoid bone  olfactory nerve) -Note risk of anosmia with head trauma (shearing of these fibres. Receptor cells have olfactor ...
GI Physiology - joshcorwin.com
GI Physiology - joshcorwin.com

... released by the pancreas in an inactive form; can’t do anything when they are released from the pancreas. Their inactive forms are trypsinogen, chymotripsinogen, procarboxypeptidase. In order to function they need to be activated. Trypsinogen is activated into trypsin by the enzyme enterokinase loca ...
Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis (ALS)

... There is currently no cure for ALS. Substantial research has been done and is still ongoing in an effort to determine effective treatments and ultimately a cure. ...
MODULE 4: MOTOR AND SOMATOSENSORY PATHWAYS
MODULE 4: MOTOR AND SOMATOSENSORY PATHWAYS

... As seen above, going from the lateral surface of cortex to the medial surface somatotopic organization goes from throat to face to hand/arm, to the leg. The knee is at the entrance to the interhemispheric fissure and the lower leg is on the medial surface of the hemisphere. Finally, the foot is “sta ...
The effect of spinal cord injury on the neurochemical properties of
The effect of spinal cord injury on the neurochemical properties of

... April N. Herritya,b, Jeffrey C. Petruskaa,b,c, David P. Stirlingb,c,d, Kristofer K. Raua,b,e and ...
Human Physiology - Orange Coast College
Human Physiology - Orange Coast College

... Schwann cells: ...
Early Microglial Activation Precedes Neuronal Loss in Mouse Model of Progressive
Early Microglial Activation Precedes Neuronal Loss in Mouse Model of Progressive

... neurologic symptoms, including ataxia and dysarthria, appear as the disease progresses but cognition is essentially preserved (3Y5). Symptomatic pharmacologic and rehabilitative management including psychosocial support are the mainstay of EPM1 patient care (5). EPM1 is caused by loss-of-function mu ...
Chap016, Chapter 16: Autonomic Nervous System
Chap016, Chapter 16: Autonomic Nervous System

... receptors on the back to the somesthetic area of the cerebral cortex. The somesthetic area perceives the sensation and projects the sensation to the surface of the back. The somesthetic area also sends the sensation to the somesthetic association area, where it is recognized and evaluated. This woul ...
Nervous Systems
Nervous Systems

... profound change occurs in the forebrain, which gives rise to the cerebrum • The outer portion of the cerebrum called the cerebral cortex surrounds much of the brain ...
Role of Glucose-Induced Oxidative Stress - Diabetes
Role of Glucose-Induced Oxidative Stress - Diabetes

... 4-month diabetic BB rats, there was no dorsal root ganglion sensory neuron cell death (10); however, by 10 months there was progressive neuronal loss, but prominent only in the small dorsal root ganglion neuron population and not involving apoptosis (11). At the same time there was a significant dec ...
brain anatomy - Sinoe Medical Association
brain anatomy - Sinoe Medical Association

... The insular cortex is a complex structure which contains areas that subserve visceral sensory, motor, vestibular, and somatosensory functions. The role of the insular cortex in auditory processing was poorly understood until recently. However, recent case studies indicate that bilateral damage to t ...
The Central Nervous System
The Central Nervous System

... Information travels within the nervous system primarily in the form of propagated electrical signals known as action potentials. The most important information (e.g., vision, balance, movement), is carried by myelinated axons. ...
Chapter_013
Chapter_013

... Epinephrine can activate all alpha and beta receptors, but not dopamine receptors. Norepinephrine can activate alpha1, apha2, and beta1 receptors, but not beta2 or dopamine receptors. Dopamine can activate alpha1, beta1, and dopamine receptors. Note: Dopamine is the only neurotransmitter capable of ...
absence of an intact nerve terminal in the motor end
absence of an intact nerve terminal in the motor end

... It is now well known that partial denervation ofskeletal muscle causes intact motor axons to sprout and reinnervate denervated muscle fibres (Van Harreveld, 1945; Edds, 1950; Brown, Holland & Hopkins, 1982). If the damaged motor axons are allowed to regenerate, re-formation of neuromuscular junction ...
to a  of the units.
to a of the units.

... to and from the CNS. The CNS controls the body by sending messages that flow through the motor nerves to control muscles. Sensory nerves relay messages about touch, pressure, temperature, pain, sound, vision, smell, and taste to the CNS. Thus, motor nerve messages travel from the CNS out to the musc ...
Optic Atrophy
Optic Atrophy

... Optic atrophy is the ultimate end result of diseases that cause degeneration of axons of the ganglion cells, and manifests as changes in the color and the structure of the optic disc. It is associated with variable degrees of visual dysfunction. The optic nerve contains approximately 1.2 million axo ...
Espasticidad,!!nuevos!conceptos!fisiológicos!y!patofisiológicos
Espasticidad,!!nuevos!conceptos!fisiológicos!y!patofisiológicos

... system$ in$ the$ encephalon.$ It$ is$ defined$ as$ an$ augmentation$ of$ myotatic$ reflex$ or$ muscular$ stretch$ reflex$ that$ depends$ of$ the$ muscular$ movement$ for$ its$ manifestation.$ Pathogenic$ mechanisms$ involved$ in$ this$ disorder$ include$ an$ increased$ neuronal$ excitation$(due$to$g ...
1) Discuss if NOCICEPTORS are real. 2) Describe the distribution of
1) Discuss if NOCICEPTORS are real. 2) Describe the distribution of

... stimulus which would become noxious if  prolonged. Note: Avoid use of terms like pain  receptor, pain pathway, etc*. *The terms to avoid were originally suggested by Sherrington since these cells could  produce reflexes in spinal animals that could not detect “pain”.  ...
Centrosome Motility Is Essential for Initial Axon Formation in the Neocortex
Centrosome Motility Is Essential for Initial Axon Formation in the Neocortex

... reported to be opposite to the site of axon formation (Zolessi et al., 2006). Moreover, flies without centrioles develop normal neurons (Basto et al., 2006). It was demonstrated, however, that the Golgi apparatus is a source of a large number of noncentrosomal microtubules (Efimov et al., 2007) that ...
Nerves
Nerves

... • Glia have numerous functions – Astrocytes provide structural support for neurons, regulate extracellular ions and neurotransmitters, and induce the formation of a blood-brain barrier that regulates the chemical environment of the CNS – Radial glia play a role in the embryonic development of the n ...
spinal cord and reflexes - Sinoe Medical Association
spinal cord and reflexes - Sinoe Medical Association

... §  CNS is established during the first month of development  §  Gender­specific areas appear in response to testosterone (or lack thereof)  §  Maternal exposure to radiation, drugs (e.g., alcohol and opiates), or infection can harm the fetus’ developing  CNS  §  Smoking decreases oxygen in the blood ...
Roles for miRNAs in Timing Developmental Progression Within
Roles for miRNAs in Timing Developmental Progression Within

... In their role as heterochronic genes in C. elegans, lin4, and let-7 family miRNAs function globally (Moss, 2007). However, if miRNAs are to function as timers in the developmental progression of neurons, they must show dynamic and/or localized expression: They may be transiently expressed globally o ...
video slide - Welcome to HCC Southeast Commons
video slide - Welcome to HCC Southeast Commons

... • Glia have numerous functions – Astrocytes provide structural support for neurons, regulate extracellular ions and neurotransmitters, and induce the formation of a blood-brain barrier that regulates the chemical environment of the CNS – Radial glia play a role in the embryonic development of the n ...
Ch 49
Ch 49

... • Glia have numerous functions – Astrocytes provide structural support for neurons, regulate extracellular ions and neurotransmitters, and induce the formation of a blood-brain barrier that regulates the chemical environment of the CNS – Radial glia play a role in the embryonic development of the n ...
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Neuroregeneration

Neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. Such mechanisms may include generation of new neurons, glia, axons, myelin, or synapses. Neuroregeneration differs between the peripheral nervous system (PNS) and the central nervous system (CNS) by the functional mechanisms and especially the extent and speed. When an axon is damaged, the distal segment undergoes Wallerian degeneration, losing its myelin sheath. The proximal segment can either die by apoptosis or undergo the chromatolytic reaction, which is an attempt at repair. In the CNS, synaptic stripping occurs as glial foot processes invade the dead synapse.Nervous system injuries affect over 90,000 people every year. It is estimated that spinal cord injuries alone affect 10,000 each year. As a result of this high incidence of neurological injuries, nerve regeneration and repair, a subfield of neural tissue engineering, is becoming a rapidly growing field dedicated to the discovery of new ways to recover nerve functionality after injury. The nervous system is divided into two parts: the central nervous system, which consists of the brain and spinal cord, and the peripheral nervous system, which consists of cranial and spinal nerves along with their associated ganglia. While the peripheral nervous system has an intrinsic ability for repair and regeneration, the central nervous system is, for the most part, incapable of self-repair and regeneration. There is currently no treatment for recovering human nerve function after injury to the central nervous system. In addition, multiple attempts at nerve re-growth across the PNS-CNS transition have not been successful. There is simply not enough knowledge about regeneration in the central nervous system. In addition, although the peripheral nervous system has the capability for regeneration, much research still needs to be done to optimize the environment for maximum regrowth potential. Neuroregeneration is important clinically, as it is part of the pathogenesis of many diseases, including multiple sclerosis.
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