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Spinal Cord - Sydney University Medical Society
Spinal Cord - Sydney University Medical Society

...  Joint Receptors - these are carried via Type II fibres (~30-70m/s) o Pain / Temperature  A-delta Free Nerve Endings – these Type III fibres have small amount of myelin and are associated with sharp, local pain which is typically superficial (~0.5-2m/s)  C Free Nerve Endings – these Type IV fibre ...
Cortical Plasticity - Lund University Publications
Cortical Plasticity - Lund University Publications

... information is processed in a series of relay regions, and this is a common organizational principle for sensory systems. For touch, there are only two relays on the path between the receptors in the skin and the somatosensory cortex. The receptor neurons are located in ganglions on the dorsal root ...
A comparison of the distribution and morphology of ChAT
A comparison of the distribution and morphology of ChAT

... Renewed interest in the structure and function of the spinal cholinergic neuronal system has been increased in recent years by the study associated with impairment of cholinergic functions. Indeed, a reduced activity of cholinergic motoneurons (Oda, ...
descending projections from the trigeminal ganglion and
descending projections from the trigeminal ganglion and

... neurons involved in the somatosensory processing from the orofacial region. The types of neurons, located in the trigeminal ganglion (TG) and mesencephalic trigeminal nucleus (MTN), are reviewed. Critically evaluating recent literature, the topics covered by the ongoing studies include the trigemina ...
Fernando de Castro and the discovery of the arterial chemoreceptors
Fernando de Castro and the discovery of the arterial chemoreceptors

... A few pages down, de Castro wrote: “The Glomus represents an organ with multiple receptors furnished with specialized receptor cells like those of other sensory organs [taste buds?]. . .As a plausible hypothesis we propose that the Glomus caroticum represents a sensory organ, at present the only one ...
Auris Nasus Larynx 34 (2008) 1-10
Auris Nasus Larynx 34 (2008) 1-10

... coplanar canals is opposite to each other. In this way, a given rotation produces excitation in one canal and decreased neural input from the opposite coplanar canal, greatly enhancing the differential response delivered to the brainstem for a VOR response. This difference in the input is also enhan ...
Adult Neural Stem Cells and Repair of the Adult
Adult Neural Stem Cells and Repair of the Adult

... Second, injured axons of mature neurons in the adult CNS do not spontaneously regenerate to reform connections (12–14). This is largely due to the presence of growth inhibitory factors in the adult CNS environment (12–14). Many inhibitory factors have been recently identified, including those associ ...
Ectodermal Placodes: Contributions to the
Ectodermal Placodes: Contributions to the

... of the validity of this hypothesis. It has also been suggested that migrating neural crest cells initiate or influence placodal development. The presence of placode-derived cranial sensory ganglia after extirpation of the precursors of the neural crest contribution to that ganglion suggests that pla ...
pain_etiology32
pain_etiology32

... within the intradiscal space, postsurgical epidural scars, degenerated facet joints CNS sensitization and reorganization ...
Sympathetic nervous system and inflammation: A conceptual view
Sympathetic nervous system and inflammation: A conceptual view

... input systems to the motor systems communicate bidirectionally with each other (upper part of the figure). Integral components of behavior are sensations, affective– motivational processes and cognitive processes which are dependent on cortical activity. Designed after Swanson (2000, 2008). ...
Disorders of the Spinal Cord
Disorders of the Spinal Cord

... • posterior (dorsal) column tract (sensory fibres subserving position, vibration and discriminative touch enter and directly join the posterior, dorsal columns) • spinocerebellar tract (sensory fibres transmitting unconscious proprioception connect with cells of the posterior horn – posterior grey c ...
Somatosensory and Pain
Somatosensory and Pain

... Spinal changes Axonal sprouting in spinal cord For example, normally C-fibers and A-delta fibers connect to different laminae - after peripheral nerve injury, axons will grow into each others’ layers. Perhaps explains why normally non-painful mechanical stimulation or touch sensation becomes painfu ...
Name
Name

... Introduction: A reflex arc is a way of visualizing the direction of transmission of nerve signals. The arc begins with a receptor, a specialized cell which is stimulated by a change in the environment. For example, some receptors in the skin are sensitive to heat, others to pressure, and so on. If s ...
Loss of cell adhesion molecule CHL1 improves homeostatic
Loss of cell adhesion molecule CHL1 improves homeostatic

... decreased in the cerebral cortex, hypothalamus, and brain stem and increased in the cerebellum after the induction of AH. Thus, we hypothesized that CHL1 may be involved in the regulation of the hypoxic response in vivo. To address this possibility, CHL1  /  mice and wild-type littermates were sub ...
Central Nervous System (CNS) The Brain Embryonic Development
Central Nervous System (CNS) The Brain Embryonic Development

... • Pineal gland – extends from the posterior border and secretes melatonin • Melatonin – a hormone involved with sleep regulation, sleep-wake cycles, and mood ...
Morphometric changes of the central nervous system of
Morphometric changes of the central nervous system of

... 2002a; JACUÑSKI et al. 2004; TEMPLIN et al. 2009; NAPIÓRKOWSKA & TEMPLIN 2013). In addition, the anatomy of the spiders (particularly their nervous and digestive systems) was evaluated for structural anomalies (JACUÑSKI 1983; JACUÑSKI et al. 2002b; NAPIÓRKOWSKA et al. 2010; NAPIÓRKOWSKA et al. 2013) ...
neonatal 6-hydroxydopamine treatment eliminates cholinergic
neonatal 6-hydroxydopamine treatment eliminates cholinergic

... gland, and many blood vessels but did not noticeably affect AChE and VIP staining or axonal ultrastructure in the sweat glands. However, treatment with higher doses of 6-OHDA did cause significant axonal degeneration. The response of the sympathetic innervation of developing but not mature sweat gla ...
aud
aud

... ear contains specialized sensory receptor cells called hair cells. These cells are responsible for converting the vibratory energy that enters the auditory system into nerve impulses that are transmitted to the central nervous system via the auditory nerve. In addition to the conversion of vibratory ...
New perspectives on the evolution of protochordate sensory and
New perspectives on the evolution of protochordate sensory and

... ascidian balance organs, i.e. the otolith and photolith. In fact, if the sensory vesicle in ancestral ascidians was originally a longer structure, more like the amphioxus cerebral vesicle, reducing its length would bring the pigment and sensory cells of the ancestral frontal eye closer to the ciliar ...
neuroanatomy - NC State Veterinary Medicine
neuroanatomy - NC State Veterinary Medicine

... The rostral colliculus in mammals has 7 layers - 3 cellular (strata griseum superficiale, intermediate, and profundus) alternating with 4 of fibers (strata zonale, opticum, album intermediale, and album profundum). Retinotectal fibers generally pass through the stratum opticum, and enter the superfi ...
Trigeminal Ganglion Cell Processes Are
Trigeminal Ganglion Cell Processes Are

... to occur under the directive guidance of periphery (Van der Loos and DGrfl, 1978; Van der Loos and Welker, 1985; Woolsey, 1987). However, little is known about developmental strategies used by trigeminal ganglion cells to match topographically equivalent regions of the periphery and brainstem. Nor i ...
Hierarchy of the heart rhythmogenesis levels is a
Hierarchy of the heart rhythmogenesis levels is a

... while the parasympathetic ones decelerate it. This understanding we supported by multiple experiments with cutting and subsequent electrical stimulation of the extracardiac (parasympathetic and sympathetic) nerves. It has been established that rhythmic modulation was dependent on the speeding up of ...
Peripheral Nervous System (PNS) PNS – all neural structures
Peripheral Nervous System (PNS) PNS – all neural structures

... -Axon and myelin sheath distal to injury disintegrate due to lack of nutrients from the cell body (Wallerian degeneration) -Neurilemma remains intact -Schwann cells proliferate and migrate to injury site and form a regeneration tube that guide axon sprouts -Cell body changes; chromatophilic substanc ...
Thalamocortical projection from the ventral posteromedial nucleus
Thalamocortical projection from the ventral posteromedial nucleus

... injection. In these columns, labeled axonal fibers formed dense plexus in layers IV and VI. Most of these fibers extended vertically in the columns and were highly branched (indicated by arrows in Fig. 1B). Different types of axon were also present. They entered SI distant from target sites, extende ...
Number, size and distribution of ganglion neurons in urinary bladder
Number, size and distribution of ganglion neurons in urinary bladder

... certain important laboratory animals, such as Calomys callosus, are not available in the literature. This animal is a cricetine rodent, similar to a mouse, commonly found in fields of South America, analyzed in some biological aspects as immunology and physiology (Petter et al, 1967; Justines and Jo ...
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Neuroregeneration

Neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. Such mechanisms may include generation of new neurons, glia, axons, myelin, or synapses. Neuroregeneration differs between the peripheral nervous system (PNS) and the central nervous system (CNS) by the functional mechanisms and especially the extent and speed. When an axon is damaged, the distal segment undergoes Wallerian degeneration, losing its myelin sheath. The proximal segment can either die by apoptosis or undergo the chromatolytic reaction, which is an attempt at repair. In the CNS, synaptic stripping occurs as glial foot processes invade the dead synapse.Nervous system injuries affect over 90,000 people every year. It is estimated that spinal cord injuries alone affect 10,000 each year. As a result of this high incidence of neurological injuries, nerve regeneration and repair, a subfield of neural tissue engineering, is becoming a rapidly growing field dedicated to the discovery of new ways to recover nerve functionality after injury. The nervous system is divided into two parts: the central nervous system, which consists of the brain and spinal cord, and the peripheral nervous system, which consists of cranial and spinal nerves along with their associated ganglia. While the peripheral nervous system has an intrinsic ability for repair and regeneration, the central nervous system is, for the most part, incapable of self-repair and regeneration. There is currently no treatment for recovering human nerve function after injury to the central nervous system. In addition, multiple attempts at nerve re-growth across the PNS-CNS transition have not been successful. There is simply not enough knowledge about regeneration in the central nervous system. In addition, although the peripheral nervous system has the capability for regeneration, much research still needs to be done to optimize the environment for maximum regrowth potential. Neuroregeneration is important clinically, as it is part of the pathogenesis of many diseases, including multiple sclerosis.
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