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Topic # 7: Nucleic Acids
Topic # 7: Nucleic Acids

... A. Regulation of gene expression by proteins 1. Gene expression is regulated by proteins that bind to specific base sequences in DNA 2. Some proteins are always necessary for the survival of an organism 3. These are expressed in an unregulated fashion 4. Other proteins need to be produced at certain ...
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A Physiological Approach to DNA Music

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... An alternative form of the same gene. Gene e.g. Height – alleles – tall, small. Chromosome A single DNA strand that has been supercoiled/condensed/contracted. Can only be seen when the cell begins to divide. One is paternal (from father) one is maternal (from mother). Gene locus The fixed position o ...
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AQA Biology: Genetics, populations, evolution
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United Kingdom National DNA Database

The United Kingdom National DNA Database (NDNAD; officially the UK National Criminal Intelligence DNA Database) is a national DNA Database that was set up in 1995. As of the end of 2005, it carried the profiles of around 3.1 million people. In March 2012 the database contained an estimated 5,950,612 individuals. The database, which grows by 30,000 samples each month, is populated by samples recovered from crime scenes and taken from police suspects and, in England and Wales, anyone arrested and detained at a police station.Only patterns of short tandem repeats are stored in the NDNAD – not a person's full genomic sequence. Currently the ten loci of the SGM+ system are analysed, resulting in a string of 20 numbers, being two allele repeats from each of the ten loci. Amelogenin is used for a rapid test of a donor's sex.However, individuals' skin or blood samples are also kept permanently linked to the database and can contain complete genetic information. Because DNA is inherited, the database can also be used to indirectly identify many others in the population related to a database subject. Stored samples can also degrade and become useless, particularly those taken with dry brushes and swabs.The UK NDNAD is run by the Home Office, after transferring from the custodianship of the National Policing Improvement Agency (NPIA) on 1 October 2012. A major expansion to include all known active offenders was funded between April 2000 and March 2005 at a cost of over £300 million.
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