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DNA Replication
DNA Replication

... 2. A free 3'OH group is required for replication, but when the two chains separate no group of that nature exists. RNA primers are synthesized, and the free 3'OH of the primer is used to begin replication. 3. The replication fork moves in one direction, but DNA replication only goes in the 5' to 3' ...
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Foundations of Biology.pptx
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... What about the last Okazaki fragment at the end of the chromosome (the telomere)? No DNA synthesis occurs because there is no 3’ end to extend —a single-stranded bit of DNA is left at each end. If left, these single-stranded regions would be removed after replication; after many replications, contin ...
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Biology 321 Spring 2013 Assignment Set 7 Reading Assignments in
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Gene Isolation and Manipulation

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... also two copies of each of the genes. The exception to this rule applies to the genes carried on the sex chromosomes, X and Y. Since men have only one copy of the X chromosome, they have only one copy of all the genes carried on the X chromosome. Women have two copies of the X chromosome in their ce ...
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Introduction to Molecular Pathology

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United Kingdom National DNA Database

The United Kingdom National DNA Database (NDNAD; officially the UK National Criminal Intelligence DNA Database) is a national DNA Database that was set up in 1995. As of the end of 2005, it carried the profiles of around 3.1 million people. In March 2012 the database contained an estimated 5,950,612 individuals. The database, which grows by 30,000 samples each month, is populated by samples recovered from crime scenes and taken from police suspects and, in England and Wales, anyone arrested and detained at a police station.Only patterns of short tandem repeats are stored in the NDNAD – not a person's full genomic sequence. Currently the ten loci of the SGM+ system are analysed, resulting in a string of 20 numbers, being two allele repeats from each of the ten loci. Amelogenin is used for a rapid test of a donor's sex.However, individuals' skin or blood samples are also kept permanently linked to the database and can contain complete genetic information. Because DNA is inherited, the database can also be used to indirectly identify many others in the population related to a database subject. Stored samples can also degrade and become useless, particularly those taken with dry brushes and swabs.The UK NDNAD is run by the Home Office, after transferring from the custodianship of the National Policing Improvement Agency (NPIA) on 1 October 2012. A major expansion to include all known active offenders was funded between April 2000 and March 2005 at a cost of over £300 million.
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