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Pharmacology Objectives 2
Pharmacology Objectives 2

... the drug and the interacting compound. If the ED50 is at a higher dose for the drug plus compound then potency was decreased and if the ED50 is at a lower response then the efficacy was decreased. 3. Define graded and quantal dose-response curves. Graded dose-response curves – the response to a give ...
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Non-Cardiac Chest Pain - Old

... * Cannot be given orally (MAO and COMT) * Necrosis with extravasation * Drug interactions • MAOI, TCA, general anesthetics, adrenergic blocking agents ...
Psychostimulants in the treatment of children diagnosed with ADHD
Psychostimulants in the treatment of children diagnosed with ADHD

... Abstract. Millions of children in North America are diagnosed with attention deficit/hyperactivity disorder and treated with psychostimulants such as methylphenidate, dextroamphetamine, and methamphetamine. These drugs produce a continuum of central nervous system toxicity that begins with increased ...
Neuroleptics - Univerzita Karlova v Praze
Neuroleptics - Univerzita Karlova v Praze

... Inhibition of MAO - increases the levels of amine neurotransmitters in neurons and increases the levels of neurotransmitters which are released. MAO exists in two forms, A and B which are encoded by separate genes. Both forms of MAO are found mostly in the outer membranes of mitochondria in both neu ...
Introduction to Pharmacology
Introduction to Pharmacology

... structure of its receptor, employing at present suitable computer programs. Only few drugs in clinical use at present were developed in this rational way. Most drugs were in the past developed through random testing of chemicals , or modified molecules of known drugs that are known to have some othe ...
interactions between antihypertensive agents and other drugs
interactions between antihypertensive agents and other drugs

... This interaction holds for hypnotics, anxiolytics (minor tranquillizers), antipsychotics (neuroleptics, major tranquillizers), anti-epileptics, and opioids, but also for drugs with central nervous depressant adverse reactions, such as antihistamines, centrally acting antitussives (codeine, etc.), an ...
ANXIOLYTICS AND HYPNOTICS
ANXIOLYTICS AND HYPNOTICS

... All the benzodiazepines have shown anticonvulsant activity in animal tests Clonazepam used as an antiepileptic and diazepam in acute seizures ...
Pharmacology药理学
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Novel psychoactive substances of interest for psychiatry
Novel psychoactive substances of interest for psychiatry

... some 50 years ago. It can be produced in clandestine laboratories using a relatively simple synthesis with readily available and inexpensive source materials. It is typically ingested orally. Gamma-butyrolactone (GBL) and 1,4-butanediol, both industrial chemicals, are also currently used for their G ...
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Pharm_essays_2005_B

... Most clinically important interactions involve the effect of one drug on the metabolism of another. Drug metabolism involves phase I reactions (oxidation, reduction and hydrolysis) and phase II reactions (conjugation of the drug with other substances). Phase I reactions generally involve the CYP450 ...
anticholinergic drugs
anticholinergic drugs

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Protective Effect of Hypericum triquetrifolium Turra. on
Protective Effect of Hypericum triquetrifolium Turra. on

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rohypnol – flunitrazepam – (roofies)
rohypnol – flunitrazepam – (roofies)

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Unit 4: Systemic Drugs

... • The THC is broken down first into and active metabolite, and then into an inactive one (THC-COOH) • This metabolite is excreted from the body slowly, with a half life between 30 and 60 hours • This means that urine tests for this metabolite can be positive for days ...
Urine Drug Screen
Urine Drug Screen

... morphine are powerful analgesics used in prescription drugs. However, heroin, a synthetic derivative of morphine, is only used as an abused drug. Heroin can be taken several ways: smoking, nasal inhalation, subcutaneous injections and intravenous injections. Amphetamines are mind-altering stimulants ...
drl_DAIDS_NVP_final_ risk_list_7_2010
drl_DAIDS_NVP_final_ risk_list_7_2010

... flu-like feeling, blisters, mouth sores, facial swelling, red eyes and irritation of the eyes, general feeling of discomfort, and/or liver damage described above, kidney problems, and/or changes in white blood cell levels. Muscle break down causing muscle aches or pain has been observed in some peop ...
Antiarrhythmic Drugs - Website of Neelay Gandhi
Antiarrhythmic Drugs - Website of Neelay Gandhi

... Class I: Na Channel blockers ...
351 Pharmacology PNS 5th Lecture F
351 Pharmacology PNS 5th Lecture F

... receptors, but nicotine and lobeline (a plant derivative similar to nicotine) affect ganglia preferentially  In spite of the smaller ratio of nicotinic to muscarinic receptors in the brain, nicotine and lobeline have important effects on the brainstem and cortex.  The mild alerting action of nicot ...
Sympatholytics
Sympatholytics

... tends to cause blood to pool in the lower extremities. However, several reflexes, including sympathetically mediated venoconstriction minimize this pooling and maintain cerebral perfusion. If these reflex actions do not occur, then orthostatic hypotension could result. ...
The serotonin RECEPTOR antagonists NAN
The serotonin RECEPTOR antagonists NAN

... Some aspects of locomotor activity and the stereotyped behavior induced by methamphetamine, a known drug of abuse worldwide, are probably a consequence of the release of dopamine from dopaminergic nerve terminals, particularly in the neostriatum. With higher doses of methamphetamine, disturbances of ...
Drug Interactions Pharmacolgoy Prof. R. K. Dixit
Drug Interactions Pharmacolgoy Prof. R. K. Dixit

... Phenytoin Carbamazepine Rifampin Cigarette smoking Chronic alcoholism Pollutants ...
drug interactions
drug interactions

... Phenytoin Carbamazepine Rifampin Cigarette smoking Chronic alcoholism Pollutants ...
10 Similarities of Sugar, Junk Food and Drugs
10 Similarities of Sugar, Junk Food and Drugs

... which areas in the brain are being activated. Using such devices, studies have shown that both food and drug cues activate the same brain regions, and that the same areas are activated when people crave either junk food or drugs (14, 15). 4. A Tolerance to the “Rewarding” Effects Builds up When the ...
corticosteroids - Crohn`s and Colitis Foundation of America
corticosteroids - Crohn`s and Colitis Foundation of America

... Medical treatment for Crohn’s disease and ulcerative colitis has two main goals: achieving remission (control or resolution of inflammation leading to symptom resolution) and then maintaining remission. To accomplish these goals, treatment is aimed at controlling the ongoing inflammation in the inte ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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