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Comparison of antiepileptic drug prescribing in children in three
Comparison of antiepileptic drug prescribing in children in three

... type (conventional vs. newer AEDs). We also analyzed the frequency of AEDs prescribed for children and adolescents with an indication/diagnosis of epilepsy for all three databases together. Due to the absence of adolescent data in PEDIANET, prevalence of AED use for comparison in three countries was ...
Loteprednol etabonate - Therapeutic Goods Administration
Loteprednol etabonate - Therapeutic Goods Administration

... In relation to preservative efficacy, this will be tested only in the event of a benzalkonium chloride assay failure on stability, and if tested, then according to both United States Pharmacopeia (USP) and European Pharmacopeia (EP) requirements. This was acceptable to the TGA. In relation to the sh ...
Efficacy of atypical v. typical antipsychotics in the treatment of early
Efficacy of atypical v. typical antipsychotics in the treatment of early

... to extrapyramidal side-effects.13 Their younger age also puts them at risk of longer exposure to the potential metabolic complications of newer antipsychotics.14 Avoiding adverse effects when individuals first start treatment is particularly important as it may colour their attitude to medication an ...
AuspAR: Cabazitaxel - Therapeutic Goods Administration
AuspAR: Cabazitaxel - Therapeutic Goods Administration

... Cabazitaxel is a semisynthetic compound derivative from 10-deacetylbaccatin III, which is extracted from European yew needles. This new taxane, which promotes the tubulin assembly in vitro and stabilises microtubules against cold induced depolymerisation as efficiently as docetaxel, was selected for ...
Australian Public Assessment Report for loteprednol etabonate Proprietary Product Name: Lotemax
Australian Public Assessment Report for loteprednol etabonate Proprietary Product Name: Lotemax

... In relation to preservative efficacy, this will be tested only in the event of a benzalkonium chloride assay failure on stability, and if tested, then according to both United States Pharmacopeia (USP) and European Pharmacopeia (EP) requirements. This was acceptable to the TGA. In relation to the sh ...
Anxiety Disorder - National Medical Research Council
Anxiety Disorder - National Medical Research Council

... the best available evidence at the time of development. Adherence to these guidelines may not ensure a successful outcome in every case, nor should they be construed as including all proper methods of care or excluding other acceptable methods of care. Each physician is ultimately responsible for th ...
INSOMNIA
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Novel analgesic combination of tramadol
Novel analgesic combination of tramadol

... without radiating pain no lower than the knee were included in the study. Acute back pain had started at least 72 h prior to inclusion in the study and not more than 6 weeks of duration. Otherwise in good health, as determined by physical examination and medical history. The major study exclusion cr ...
Answer the following questions
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Facilitative effects of an adenosine A1/A2 receptor blockade on
Facilitative effects of an adenosine A1/A2 receptor blockade on

... is evidence that brain extracellular adenosine levels vary significantly during the light – dark cycle, we tested the effects of theophylline both during the light and the dark period. Acquisition of the task was investigated for 10 consecutive days after rats received daily injections of vehicle or ...
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Artiaga Nicole Artiaga Professor David Wirthlin Writing 39C 12
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This is the English version of the scientific brochure for Remifemin in
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Comparison of Tibial Intraosseous, Sternal Intraosseous
Comparison of Tibial Intraosseous, Sternal Intraosseous

... rapidly establish vascular access to administer lifesaving drugs. Given that the patient is in a state of cardiovascular compromise, vascular access procedures become difficult and time-consuming. The difficulty and delay in establishing vascular access may be magnified during mass casualty scenario ...
Comparative evaluation of Nigella sativa (Kalonji) and simvastatin
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... respectively. Moreover, HDL-C levels of rats in this group showed 53.5% improvement after treatment. In accordance with our results, N. sativa found an effective lipid-lowering drug in combination with simvastatin (Dahri et al., 2005; Kaatabi et al., 2012). However, we reported here its comparison w ...
Cough and Angioedema in Patients Receiving Angiotensin
Cough and Angioedema in Patients Receiving Angiotensin

... antihypertensive agents; however, this adverse effect occurred, though exceptionally, with all the agents, including ARBs. The study by Miller et al. included a larger number of patients, had a longer follow-up period and investigated the presence of angioedema with other antihypertensive drugs, com ...
Substance Abuse in Boston 2011 - Boston Public Health Commission
Substance Abuse in Boston 2011 - Boston Public Health Commission

... abusers to talk about their problem, lack of health care coverage or not enough coverage, and inadequate funding for treatment beds and facilities (3,4). In addition to personal health consequences, the effect of substance abuse also results in negative outcomes for both individuals and society. Fo ...
EMS5121
EMS5121

... adequately screened to determine if they are at risk for bipolar disorder; such screening should include a detailed psychiatric history, including a family history of suicide, bipolar disorder, and depression. It should be noted that EMSAM is not approved for use in treating bipolar depression. 5.2 ...
Week 8 Review Pharmacology
Week 8 Review Pharmacology

... Beta blockers reduce ______ _______, diminishing sympathetic NS Response and thereby diminishing vascular resistance. __________ beta blockers such as propranolol (Inderal), inhibit beta1(heart) and beta2(bronchial) receptors, heart & resp rates slow with secondary blood pressure decrease and bronch ...
Predicting outcomes and drug resistance with standardised treatment of active tuberculosis O. Oxlade*
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International Journal of Experimental pharmacology
International Journal of Experimental pharmacology

... Email:- [email protected] ...
The role of drug therapies in the treatment of anorexia and bulimia
The role of drug therapies in the treatment of anorexia and bulimia

... received either desipramine (150 mg/day) for six weeks, and no drug for three weeks, followed by placebo for six weeks or the reverse sequence. In terms of reduction in binge frequency, seven responders were identified; another seven were found to be borderline responders, while 10 were labelled as ...
Drugs used for the immobilization, capture, and translocation of wild
Drugs used for the immobilization, capture, and translocation of wild

... controlled under the Medicines and Related Substances Control Act No. 101 of 1965. The Act provides that all medicinal substances be placed into nine schedules, representing four main groups, according to safety profile and use. Scheduling determines the availability and type of control placed on a ...
Hepatotoxicity by Acetaminophen and Amiodarone in
Hepatotoxicity by Acetaminophen and Amiodarone in

... compared to human.1,2 The size, embryonic and larval development gives additional advantages over other in vitro and mammalian model. Zebrafish embryos are transparent so it is very easy to observe organ development. The size of embryos is very small which enable to put the larvae in a petriplates a ...
Current status and future potential.
Current status and future potential.

... airways to the alveoli (46-54). Marijuana smoke causes inflammatory changes in the airways of young people that are similar to the effects of tobacco (55). In addition to these cellular abnormalities and consequences, contaminants of marijuana smoke are known to include various pathogenic bacteria a ...
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Polysubstance dependence



A person with polysubstance dependence is psychologically addicted to being in an intoxicated state without a preference for one particular substance. Although any combination of three drugs can be used, studies have shown that alcohol is commonly used with another substance. This is supported by one study on polysubstance use that separated participants who used multiple substances into groups based on their preferred drug. The three substances were cocaine, alcohol, and heroin, which implies that those three are very popular. Other studies have found that opiates, cannabis, amphetamines, hallucinogens, inhalants and benzodiazepines are often used in combination as well. The results of a long-term or longitudinal study on substance use led the researchers to observe that excessively using or relying on one drug increased the probability of excessively using or relying on another drug.
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