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Practical and clinical use of opioids
Practical and clinical use of opioids

... frequent reasons for seeking healthcare. Acute and chronic pain result in considerable discomfort with a detrimental impact on the quality of life. Opioids are the mainstay of pain management for many patients with severe pain. Opioids are, unfortunately, also commonly abused drugs, and are well-rep ...
Nasal Route: A Potential Alternative for Antiparkinsonism Drug
Nasal Route: A Potential Alternative for Antiparkinsonism Drug

... was observed. [14] The tmax obtained for levodopa from Sinemet® CR (tmax = 4 h) was almost double that of the standard Sinemet® (tmax = 2.5 h) and was associated with much slower increase in plasma levodopa levels.[15] Due to lower frequency of administration the controlled release formulation provi ...
A Thesis entitled Ohio Pharmacists` Perceptions of Over-the
A Thesis entitled Ohio Pharmacists` Perceptions of Over-the

... 1.1.5 Trends in Over-the-counter Drug Advertising Pharmaceutical manufacturers spend a substantial amount of time and money towards the development of efficient advertising strategies.23 US pharmaceutical spending on DTCA has risen tremendously from $791 million in 1996 to $4.86 billion in 2005.24 ...
MAGNETO-OPTIC TECHNOLOGY HITS THE FIELD
MAGNETO-OPTIC TECHNOLOGY HITS THE FIELD

... In addition to health consultants, the organization would also recruit approximately 100 local "MOTCHWs" to serve each group of approximately 250 residents. These local MOT-CHWs are the existing CHW's, or if none exist, carefully selected individuals who are respected in their communities with a wi ...
RTF 588.5 KB - Productivity Commission
RTF 588.5 KB - Productivity Commission

... extremely important point. The PBS is one of the few examples of public health policy in Australia’s history that has an unequivocal democratic mandate. The PBS has evolved into a scheme which covers approximately 600 drug substances in at least double that number of forms and strengths (items), and ...
PDF - Innovare Academic Sciences
PDF - Innovare Academic Sciences

... to determine whether new drugs or treatments are both safe and effective. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people. If the drug successfully passes through Phases I, II, and III, it will usually be approved by the national regulatory a ...
Lecture-1-Opioids - Kentucky Academy of Family Physicians
Lecture-1-Opioids - Kentucky Academy of Family Physicians

... Presented by CO*RE Collaboration for REMS Education Presented by CO*RE www.core-rems.org Collaboration for REMS Education ...
Guidance for Industry Influenza:  Developing Drugs for Treatment and/or Prophylaxis
Guidance for Industry Influenza: Developing Drugs for Treatment and/or Prophylaxis

... • Protocol designs for prevention of symptomatic influenza • The role of animal data in an influenza drug development program • Considerations relating to the potential for emergency use of influenza drugs, including advance development of protocols for further exploration and verification of dru ...
Human Enhancement Drugs - Centre for Public Health
Human Enhancement Drugs - Centre for Public Health

... are plenty of manufacturers and retailers ready to exploit this demand. The fact that some of these compounds sold can have genuine actions on the body’s physiology including, in some instances, serious health threatening side effects, means that we need to review regularly whether we have adequate ...
Factors Affecting Antiretroviral Treatment Adherence amongst
Factors Affecting Antiretroviral Treatment Adherence amongst

... centres located within the six geopolitical zones in the country, more people now have increasing access to antiretroviral treatment with over 250,000 people receiving treatment in 2006. Antiretroviral treatment centres increased further from 74 to 251 between 2006 and 2008 (FMH, 2006). As at 2009, ...
Cytotoxic Drug MANUAL
Cytotoxic Drug MANUAL

... adverse effects for patients who are prescribed these drugs but healthcare workers risk adverse effects with no therapeutic benefit. Acute side effects such as skin, eye or mucous irritations and chronic effects such as cancer and adverse reproductive events can result from exposure. Appropriate han ...
Seychelles Strategy for the Prevention and Control of Non
Seychelles Strategy for the Prevention and Control of Non

... Seychelles  has  done  much  to  tackle  noncommunicable  diseases,  and  our  successes  in,  for   example,  reducing  the  use  of  tobacco  and  the  rate  of  high  blood  pressure,  are  encouraging  signs   of  what  can  be  a ...
Chapter_033
Chapter_033

... Be prepared to provide safe drug therapy patient education. Copyright © 2011, 2007, 2003, 1999 by Saunders, an imprint of Elsevier Inc. All rights reserved. ...
HIV and AIDS
HIV and AIDS

... HIV is unable to reproduce outside its living host. Although HIV has been transmitted between family members in a household setting, this type of transmission is very rare. These transmissions are believed to have resulted from contact between mucous membranes and infected blood; therefore, it does ...
Clinical Guidelines on Management of Prolonged Seizures, Serial
Clinical Guidelines on Management of Prolonged Seizures, Serial

... seizure exacerbation and induction of involuntary movements. It takes 20-25 minutes to attain its maximal anti-epileptic effect. Fosphenytoin can be used as an alternative.18 Some studies suggested that sodium valproate might also be a valuable option for established SE. In an adult randomised study ...
About the Author - Pharmacy Technician Certification
About the Author - Pharmacy Technician Certification

... Prescriptions are orders for medications in a specified dose and amount to be given in a specific time frame. Prescriptions are typically written by physicians but may also come from physician assistants (PA), dentists (DDS, DMD), podiatrists (DPM), ophthalmologists (OD) and veterinarians (DVM). In ...
Drug allergy - Journal of Allergy and Clinical Immunology
Drug allergy - Journal of Allergy and Clinical Immunology

... be safe to reintroduce the medication. If possible, the original medical record that describes the drug reaction should be reviewed. The most important components of a drug allergy history are as follows. d What is the name of the medication? Although obvious, not uncommonly, patients are unable to ...
http://www.fda.gov/downloads/ICECI/E.../UCM129812.pdf
http://www.fda.gov/downloads/ICECI/E.../UCM129812.pdf

... The FDA on September 16, 2008, issued two Warning Letters to Ranbaxy Laboratories Ltd., of the Republic of India, and an IA for generic drugs produced by Ranbaxy's Dewas and Paonta Sahib plants in India. FDA inspected the pharmaceutical manufacturing facilities on January 28 through February 12 and ...
Tobacco cessation: what role can dental professionals play?
Tobacco cessation: what role can dental professionals play?

... of death in the world. It is currently responsible for the death of one in ten adults worldwide. Every 6.5 seconds one tobacco user dies from a tobaccorelated disease somewhere in the world. Cigarettes kill half of all lifetime users and half of those die in middle age (35-69 years), losing an avera ...
Vermont Buprenorphine Practice Guidelines
Vermont Buprenorphine Practice Guidelines

... The Vermont Board of Medical Practice is obligated under the laws of the state of Vermont to protect the public health and safety. The Board recognizes that inappropriate prescribing of controlled substances, including opioids, may lead to drug diversion and abuse by individuals who seek them for ot ...
Clinical protocol for the use of syringe drivers
Clinical protocol for the use of syringe drivers

... • Does not restrict mobility and independence • Syringe only needs replacing once a day unless the prescription changes • Technically simple to set up and use compared with other devices Considerations when using a syringe driver • There is a need to anticipate the patientʼs requirements over 24 hou ...
Model Ordinance Adopting Zoning Restrictions on the
Model Ordinance Adopting Zoning Restrictions on the

... having a “high potential for abuse, lack of any accepted medical use, and absence of any accepted safety for use in medically supervised treatment.” Gonzales v. Raich, 545 U.S. 1, 14 (2005), Controlled Substance Act (CSA), 84 Stat. 1242, 21 U.S.C. 801 et seq; and WHEREAS, the voters of the State of ...
HIV - Delaware General Health District
HIV - Delaware General Health District

... Persons required to report cases of AIDS, ARC, HIV, confirmed positive tests for HIV, and HIV infections pursuant to divisions (B) and (C) of section 3701.24 of the Revised Code and this rule are as follows: [Ohio Administrative Code 3701-3-12(A-D) Effective 01/01/2009] Health Care Providers and Fac ...
Int J Tuberc Lung Dis. 2009 Aug
Int J Tuberc Lung Dis. 2009 Aug

... WHO’s ‘3 by 5’ initiative in 2003,15 NAPs have logically directed their attention and resources to providing this life-saving intervention for PLHIV, and this has diverted attention away from TB preventive activities. In April 2008, the HIV Department of the WHO took up the mantra of this initiative ...
center for global
center for global

... at the same time hastening the AIDS transition. In conformity with the view that patients currently on treatment have an entitlement to continued treatment, none of the scenarios considers the possibility of reducing support for those patients. However, many other options are on the table. We projec ...
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Harm reduction



Harm reduction (or harm minimization) is a range of public health policies designed to reduce the harmful consequences associated with various human behaviors, both legal and illegal. Harm reduction policies are used to manage behaviors such as recreational drug use and sexual activity in numerous settings that range from services through to geographical regions. Critics of harm reduction typically believe that tolerating risky or illegal behaviour sends a message to the community that such behaviours are acceptable and that some of the actions proposed by proponents of harm reduction do not reduce harm over the long term.Needle-exchange programmes reduce the likelihood of users of heroin and other drugs sharing the syringes and using them more than once. Syringe-sharing can lead to infections such as HIV or hepatitis C can spread from user to users through the reuse of syringes contaminated with infected blood. Needle and syringe programme (NSP) and Opioid Substitution Therapy (OST) outlets in some settings offer basic primary health care. Safe injection site are legally sanctioned, medically supervised facilities designed to address public nuisance associated with drug use and provide a hygienic and stress-free environment for drug consumers. The facilities provide sterile injection equipment, information about drugs and basic health care, treatment referrals, and access to medical staff.Opioid replacement therapy (ORT), or opioid substitution therapy (OST), is the medical procedure of replacing an illegal opioid, such as heroin, with a longer acting but less euphoric opioid; methadone or buprenorphine are typically used and the drug is taken under medical supervision. Another approach is Heroin assisted treatment, in which medical prescriptions for pharmaceutical heroin (diacetylmorphine) are provided to heroin-dependent people. Toronto's Seaton House became the first homeless shelter in Canada to operate a ""wet shelter"" on a ""managed alcohol"" principle in which clients are served a glass of wine once an hour unless staff determine that they are too inebriated to continue. Previously, homeless alcoholics opted to stay on the streets often seeking alcohol from unsafe sources such as mouthwash, rubbing alcohol or industrial products which, in turn, resulted in frequent use of emergency medical facilities.A high amount of media coverage exists informing users of the dangers of driving drunk. Most alcohol users are now aware of these dangers and safe ride techniques like 'designated drivers' and free taxicab programmes are reducing the number of drunk-driving accidents. Many schools now provide safer sex education to teen and pre-teen students, who may engage in sexual activity. Since some adolescents are going to have sex, a harm-reductionist approach supports a sexual education which emphasizes the use of protective devices like condoms and dental dams to protect against unwanted pregnancy and the transmission of STIs. Since 1999 some countries have legalized prostitution, such as Germany (2002) and New Zealand (2003).Many street-level harm-reduction strategies have succeeded in reducing HIV transmission in injecting drug users and sex-workers. HIV education, HIV testing, condom use, and safer-sex negotiation greatly decreases the risk to the disease.
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