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- Wiley Online Library
- Wiley Online Library

... more likely to produce an insufficient effect, and higher concentrations being more often associated with adverse effects. Therapeutic drug concentration monitoring (TDM) was initiated for a number of AEDs and used to establish optimal therapy regimens for individual patients. This approach has prov ...
Potential pitfalls of propofol target controlled infusion delivery related
Potential pitfalls of propofol target controlled infusion delivery related

... in the organism as well as the relation between the concentration of the therapeutic substance and its effect on an end organ. It also describes the interaction of drug concentration and response of the organism to the drug as a function of time. In other words, pharmacokinetics describes what happe ...
Treatment of tuberculosis - World Health Organization
Treatment of tuberculosis - World Health Organization

... countries that use the new rapid molecular-based tests, DST results for rifampicin/ isoniazid will be available within 1‒2 days and can be used in deciding which regimen should be started for the individual patient. Rapid tests eliminate the need to treat “in the dark” during the long wait for resul ...
Chapter_036 (2)
Chapter_036 (2)

... Describe how aerosols are generated. List the hazards associated with aerosol drug therapy. Describe how to select the best aerosol drug delivery system for a given patient. Copyright © 2013, 2009, 2003, 1999, 1995, 1990, 1982, 1977, 1973, 1969 by Mosby, an imprint of Elsevier Inc. ...
Guidelines for the Prevention of Mother-to-Child Transmission
Guidelines for the Prevention of Mother-to-Child Transmission

... an HIV-positive pregnant woman to her child can occur during pregnancy, labour and delivery, or through breastfeeding. The World Health Organization estimates that the risk of transmission ranges from 15 to 30% in non-breastfeeding populations and from 20 to 45% in breastfeeding populations. Without ...
Preview the material
Preview the material

... The THC content in sinsemilla (a seedless variety of marijuana) is now in the range of 10% to 20% and sometimes reaches 30%. Similar variations and increasing average potencies have been found as well for hashish. A third form of cannabis is hash oil, a concentrated liquid marijuana extract derived ...
Report of a WHO Consultation 19–21 November 2002 Geneva
Report of a WHO Consultation 19–21 November 2002 Geneva

... As treatment and care become more widely available it will be necessary to move beyond a single, rigid model of providing HIV testing and counselling and ensure that such services are available : ◗ for all those who want to know their HIV status ◗ wherever medically indicated in the context of clini ...
BRS Pharmacology - farmasi
BRS Pharmacology - farmasi

... Care has been taken to confirm the accuracy of the information present and to describe generally accepted practices. However, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, ...
MARIJUANA AND SUBSTANCE USE DISORDER, Part 1: a
MARIJUANA AND SUBSTANCE USE DISORDER, Part 1: a

... The THC content in sinsemilla (a seedless variety of marijuana) is now in the range of 10% to 20% and sometimes reaches 30%. Similar variations and increasing average potencies have been found as well for hashish. A third form of cannabis is hash oil, a concentrated liquid marijuana extract derived ...
largest ever study of cocaine use
largest ever study of cocaine use

... The Key Informant Studies attempt to address the enormous variation which exists, for example, between coca leaf chewing in Bolivia and crack use in New York. These studies involved in-depth interviews with hundreds of cocaine users: people who can provide information from their own experience of us ...
Cocaine Project
Cocaine Project

... The Key Informant Studies attempt to address the enormous variation which exists, for example, between coca leaf chewing in Bolivia and crack use in New York. These studies involved in-depth interviews with hundreds of cocaine users: people who can provide information from their own experience of us ...
Tubing Misconnections Self Assessment for Healthcare Facilities
Tubing Misconnections Self Assessment for Healthcare Facilities

... The Tubing Misconnections Self Assessment for Healthcare Facilities will help you identify devices and practices that pose a risk of inadvertent tubing misconnections and help prioritize your efforts to mitigate those risks. The self-paced and selfdirected risk analysis can be tailored to your healt ...
British HIV Association guidelines for the treatment of HIV-1
British HIV Association guidelines for the treatment of HIV-1

... 6.1.1 Interventions to increase adherence to treatment .......................................................................... 57 6.1.2 Should the choice of first-line antiretroviral therapy combination be affected by risk of nonadherence? ......................................................... ...
The  effect  of  bromhex propert
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... rheologically extremely complex, an appropriate rheometer [14] which enables the simultaneous determination of elastic and viscous parameters must be employed. Some putative mucolytic drugs affect elasticity, for example, without changing viscosity (6]. Secondly, inherent large intra- and inter-subj ...
HIV in Pregnancy : a review
HIV in Pregnancy : a review

... Most of the thirty-three million people living with HIV are in the developing world, where HIV infection in pregnancy has become the most common medical complication of pregnancy in some countries. More than 70% of all HIV infections are a result of heterosexual transmission and over 90% of infectio ...
Comorbidity of mental disorders and substance use: A brief guide for
Comorbidity of mental disorders and substance use: A brief guide for

... non-commercial use or use within your organisation. Apart from any use as permitted under the Copyright Act 1968, all other rights are reserved. Requests and inquiries concerning reproduction and rights should be addressed to Commonwealth Copyright Administration, Attorney-General’s Department, Robe ...
PCI ExTract - Clinical Trial Results
PCI ExTract - Clinical Trial Results

... ENOX can be administered as the sole antithrombin therapy before and during PCI without the need for additional antithrombin inhibition. • Periprocedural ENOX is preferable to UFH in the management of these patients. ...
abstract
abstract

... Presence of very poor oral hygiene with abundant plaque and calculus along with halitosis was noticed. Periodontal pockets were more/equal to 6mm in relation to II & III quadrant. Grade I mobility was noticed with 21 22 42 44 45 and Grade II mobility with 24 25 31 32 41. Furcation involvement was wi ...
recommendations for the use of methadone for pain
recommendations for the use of methadone for pain

... Methadone has many characteristics which make it useful for the treatment of chronic pain. Although available for many years, it has gained renewed interest due to its low cost and particular activity in neuropathic pain syndromes. Methadone is available as methadone hydrochloride in Canada, a racem ...
Kenya - CDDEP
Kenya - CDDEP

... a  larger  proportion  of  the  population  has  access  to  healthcare—including  life-­‐saving  antibiotics.  Despite   these  improvements,   the   infectious   disease   burden  in  Kenya  remains  high.  This   combination  of  improved   ƒ… ...
Access to inhaled corticosteroids is key to improving quality of care
Access to inhaled corticosteroids is key to improving quality of care

... intangible costs, which are often considerable but difficult to calculate (e.g. effects on family and social life, sporting activities, and professional or emotional repercussions). There is a lack of data regarding the overall cost of asthma morbidity and mortality in developing countries. The cost of ...
section 3 art - World Health Organization
section 3 art - World Health Organization

... Before you make your lists of supplies and equipment using this section, make sure you are clear about what you are trying to do, and what resources you have or need to be able to use the supplies and equipment. There is no point ordering items if, for example, your facility does not have staff with ...
Suppositories and Inserts
Suppositories and Inserts

...  Suppositories may be prepared by forcing the mixed mass of the base and the medicaments into special molds using suppository-making machines.  In preparation of compression into the molds, the base and the other formulative ingredients are combined by thorough mixing, the friction of the process ...
Barriers and facilitators to hepatitis C treatment for people who inject
Barriers and facilitators to hepatitis C treatment for people who inject

... practical supports such as help with accommodation and benefit access, the provision of fridges to the unstably housed, translator services and flexible service provision around the long working hours of immigrant service users. We found that a primary structural barrier to treatment uptake is the h ...
Executive Summary of the Third Report of the National Cholesterol
Executive Summary of the Third Report of the National Cholesterol

... accepted standards for costeffectiveness. Lifestyle changes are the most cost-effective means to reduce risk for CHD. Even so, to achieve maximal benefit, many persons will require LDL-lowering drugs. Drug therapy is the major expense of LDLlowering therapy and it dominates cost-effectiveness analys ...
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Harm reduction



Harm reduction (or harm minimization) is a range of public health policies designed to reduce the harmful consequences associated with various human behaviors, both legal and illegal. Harm reduction policies are used to manage behaviors such as recreational drug use and sexual activity in numerous settings that range from services through to geographical regions. Critics of harm reduction typically believe that tolerating risky or illegal behaviour sends a message to the community that such behaviours are acceptable and that some of the actions proposed by proponents of harm reduction do not reduce harm over the long term.Needle-exchange programmes reduce the likelihood of users of heroin and other drugs sharing the syringes and using them more than once. Syringe-sharing can lead to infections such as HIV or hepatitis C can spread from user to users through the reuse of syringes contaminated with infected blood. Needle and syringe programme (NSP) and Opioid Substitution Therapy (OST) outlets in some settings offer basic primary health care. Safe injection site are legally sanctioned, medically supervised facilities designed to address public nuisance associated with drug use and provide a hygienic and stress-free environment for drug consumers. The facilities provide sterile injection equipment, information about drugs and basic health care, treatment referrals, and access to medical staff.Opioid replacement therapy (ORT), or opioid substitution therapy (OST), is the medical procedure of replacing an illegal opioid, such as heroin, with a longer acting but less euphoric opioid; methadone or buprenorphine are typically used and the drug is taken under medical supervision. Another approach is Heroin assisted treatment, in which medical prescriptions for pharmaceutical heroin (diacetylmorphine) are provided to heroin-dependent people. Toronto's Seaton House became the first homeless shelter in Canada to operate a ""wet shelter"" on a ""managed alcohol"" principle in which clients are served a glass of wine once an hour unless staff determine that they are too inebriated to continue. Previously, homeless alcoholics opted to stay on the streets often seeking alcohol from unsafe sources such as mouthwash, rubbing alcohol or industrial products which, in turn, resulted in frequent use of emergency medical facilities.A high amount of media coverage exists informing users of the dangers of driving drunk. Most alcohol users are now aware of these dangers and safe ride techniques like 'designated drivers' and free taxicab programmes are reducing the number of drunk-driving accidents. Many schools now provide safer sex education to teen and pre-teen students, who may engage in sexual activity. Since some adolescents are going to have sex, a harm-reductionist approach supports a sexual education which emphasizes the use of protective devices like condoms and dental dams to protect against unwanted pregnancy and the transmission of STIs. Since 1999 some countries have legalized prostitution, such as Germany (2002) and New Zealand (2003).Many street-level harm-reduction strategies have succeeded in reducing HIV transmission in injecting drug users and sex-workers. HIV education, HIV testing, condom use, and safer-sex negotiation greatly decreases the risk to the disease.
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