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Glucophage (metformin)
Glucophage (metformin)

... been associated with some cases of lactic acidosis, GLUCOPHAGE should generally be avoided in patients with clinical or laboratory evidence of hepatic disease. GLUCOPHAGE should be temporarily discontinued in patients undergoing radiologic studies involving intravascular administration of iodinated ...
Interpreting the ACC-AHA Guidelines on Cardiovascular Disease Prevention and Cholesterol Management
Interpreting the ACC-AHA Guidelines on Cardiovascular Disease Prevention and Cholesterol Management

... clinical trials show overall a 9% increased risk for development of incident diabetes among statin users (Sattar, Lancet 2010) 2) Increased risk of diabetes only seen in those with multiple risk factors; obesity, elevated triglycerides, glucose, and hypertension are more strongly related than statin ...
Pharmacotherapy for Idiopathic Pulmonary Arterial Hypertension
Pharmacotherapy for Idiopathic Pulmonary Arterial Hypertension

... Idiopathic pulmonary arterial hypertension is the consequence of three characteristic pathologic elements: in situ thrombosis, vasoconstriction, and vascular wall remodeling. In situ thrombosis, evident in most patients, may be associated with a hypercoaguable state, fibrinolytic defects, platelet a ...
Presentation
Presentation

... microorganisms in patients with serious allergy to beta-lactam antimicrobials. Prophylaxis, as recommended by the American Heart Association, for bacterial endocarditis following certain procedures in high-risk patients. Prophylaxis for major surgical procedures involving implantation of prosthetic ...
Inhaled corticosteroids reduce growth. Or do they? REVIEW P.L.P. Brand
Inhaled corticosteroids reduce growth. Or do they? REVIEW P.L.P. Brand

... Children with asthma tend to grow slower than their healthy peers during the prepubertal years because they go into puberty at a later age. However, asthmatic children do achieve a (near) normal adult height. In randomized controlled clinical trials, the use of inhaled beclomethasone, budesonide and ...
MINDFULNESS AND TRAUMA: IMPLICATIONS FOR TREATMENT
MINDFULNESS AND TRAUMA: IMPLICATIONS FOR TREATMENT

... the broader range of trauma related problems continue to evolve. Our understanding of trauma symptoms has expanded to include the knowledge that outcomes associated with traumatic experiences are not limited to Post-traumatic Stress Disorder (PTSD) but rather extend across a range of intra- and inte ...
Document
Document

... administered him a medication, which taking resulted in less frequent attacks of bronchial asthma, but stenocardia attacks became more frequent. What medication was administered? A *Isadrin B Salbutamol C Aminophylline D Cromolyn sodium E Phenotherol 1. The patient of 40 years suffered from bronchia ...
new zealand data sheet
new zealand data sheet

... For upper respiratory tract infections due to streptococci, pneumococci, non-penicillinaseproducing staphylococci and H. influenzae) or Genito-Urinary Tract Infections (due to Escherichia coli, Proteus mirabilis and Streptococcus faecalis or Skin and Soft Tissue Infections due to streptococci, sensi ...
Pneumonia in children: Inpatient treatment Author: William J Barson
Pneumonia in children: Inpatient treatment Author: William J Barson

... Chest physiotherapy — Chest physiotherapy is not beneficial for children with uncomplicated community-acquired pneumonia (CAP) [2]. In randomized and observational studies in children and adults, chest physiotherapy had no conclusive effect on length of hospital stay, duration of fever, or radiograp ...
levodopa 2.0: new strategies to even out the peaks and valleys
levodopa 2.0: new strategies to even out the peaks and valleys

... For almost 50 years, we’ve relied on levodopa as the gold standard of symptomatic therapy of Parkinson’s disease (PD). Within this standard, Sinemet (carbidopa/levodopa) is the most commonly prescribed medication, and for good reasons: it is safe, well-tolerated and effective for motor symptoms. Lik ...
A Practical Guide to the Therapy of Narcolepsy
A Practical Guide to the Therapy of Narcolepsy

... Low cost and extemely effective. Is immediately effective on cataplexy as all antidepressants. Can be very effective at doses as low as 25 mg/day in the morning or evening, but more typically 75 mg/day is needed, with a maximum of 150 mg/day. Side effects include dry mouth, sweating, constipation, b ...
Phebra Benztropine 2 mg in 2 mL Injection
Phebra Benztropine 2 mg in 2 mL Injection

... The long duration of action of Benztropine Injection makes it particularly suitable for administration at bedtime when the effects may persist throughout the night. Consequently, Benztropine Injection enables the patient to turn in bed more easily and to rise in the morning. Therapy with other agent ...
CONCOR 5 PLUS Merck Serono
CONCOR 5 PLUS Merck Serono

... reactions. Therefore, Concor 5 plus should only be prescribed if considered essential in patients with a history of severe hypersensitivity reactions and in patients undergoing desensitisation therapy (beware of excessive anaphylactic reactions). Warnings In renal insufficiency (glomerular filtrate ...
Clinical pharmacology of anti-infectives and nonsteroidal_англ
Clinical pharmacology of anti-infectives and nonsteroidal_англ

... D. streptomycin E. para-amino salicylic acid 20. Which of the following agents used in the treatment of pulmonary tuberculosis has a toxicity of producing a lupus-like syndrome? A. *isoniazid B. rifampin C. ethambutol D. streptomycin E. para-amino salicylic acid 21. Isoniazid-induced liver damage: A ...
Kelly J. Rohan
Kelly J. Rohan

... Johnson, W. G., Roberson-Nay, R., Rohan, K. J., & Torgrud, L. (2003). An experimental investigation of DSM-IV binge eating criteria. Eating Behaviors, 4, 295-314. Rohan, K. J., Sigmon, S. T., & Dorhofer, D. M. (2003). Cognitive-behavioral factors in seasonal affective disorder. Journal of Consulting ...
The Pharmacology and Management of the Vitamin K Antagonists
The Pharmacology and Management of the Vitamin K Antagonists

... subsequent dosing based on the international normalized ratio (INR) response (Grade 2B). In the elderly and in other patient subgroups with an elevated bleeding risk, we suggest a starting dose at < 5 mg (Grade 2C). We recommend basing subsequent doses after the initial two or three doses on the res ...
Salair Inhaler
Salair Inhaler

... prime the inhaler. If the inhaler has not been used for more than one week, remove the plastic dust cap from the mouthpiece of the inhaler, shake the inhaler well and depress the canister once (into the air) to prime the inhaler. Technique for proper administration of Salair Inhaler is described in ...
Secondary traumatic stress effects of working with survivors of
Secondary traumatic stress effects of working with survivors of

... Life support was more effective in moderating work stress for women, but work support was a more effective moderator for men. Women had significantly higher burnout and life stress than did men but higher life support. Prosser et al. (1996) found higher rates of burnout in community mental health wo ...
ALL IC-BFM 2009
ALL IC-BFM 2009

... The new study protocol ALL-IC BFM 2009 is the final result of very comprehensive data analyses and discussions over the last few years. Clinical research performed within the ALLIC BFM group but also in parallel in the context of trial AIEOP-BFM ALL 2000 produced important evidence for the new strat ...
Anticoagulation-Warfarin - National Medical Research Council
Anticoagulation-Warfarin - National Medical Research Council

... is a major impediment to initiation of therapy. Warfarin has a narrow therapeutic index, with bleeding as its most serious complication. Warfarin inhibits the enzyme vitamin K epoxide reductase, which is required for the carboxylation and activation of vitamin K dependent coagulation factors II, VII ...
A review of available cholesterol- lowering medicines in South Africa
A review of available cholesterol- lowering medicines in South Africa

... The profile for statins is as follows: • Mechanism of action: Statins decrease the synthesis of cholesterol in the liver by competitively inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This decrease in the synthesis of cholesterol is accompanied by upregulation of the LDL cho ...
Myoclonus and seizures in progressive myoclonus epilepsies
Myoclonus and seizures in progressive myoclonus epilepsies

... ABSTRACT – Generalized motor seizures, usually tonic-clonic, tonicvibratory, myoclonic or clonic, and stimulus-sensitive/action myoclonus are typical features of progressive myoclonus epilepsies (PMEs). Despite the introduction of many anticonvulsants, the treatment of these symptoms, particularly m ...
Seasonal Affective Disorder
Seasonal Affective Disorder

... age. Age of onset was early 20s, although when we delved a little further, we found that many of these people had symptoms going all the way back to their childhood or adolescence. The sex ratio, which has held pretty firmly over time, is preponderantly female -- 3.1:1 in this group. And the length ...
Senior Scientist Computational Biology - Pharma
Senior Scientist Computational Biology - Pharma

... The Organisation Committed to Improving the Lives of Patients Worldwide Celgene Corporation, a uniquely positioned entrepreneurial biopharmaceutical company, and its employees are working relentlessly to provide novel solutions for unmet medical needs in cancer and debilitating inflammatory diseases ...
Omalizumab in ABPA - Stanford University
Omalizumab in ABPA - Stanford University

... Voriconazole for ABPA Much better bioavailability than itra, but much more complex metabolism (CYP2C9, CYP2C19, CYP3A4, CYP3A5). • 21 children with CF (5-16 yrs) • 13 with ABPA; 8 with sputum Af+ but no ABPA • Voriconazole for 1-50 weeks, monotherapy in 2 • Improvements in ABPA but not Af+ patients ...
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Psychedelic therapy

Psychedelic therapy refers to therapeutic practices involving the use of psychedelic drugs, particularly serotonergic psychedelics such as LSD, psilocybin, DMT, mescaline, and 2C-B, primarily to assist psychotherapy. As an alternative to synonyms such as ""hallucinogen"", ""entheogen"", ""psychotomimetic"" and other functionally constructed names, the use of the term psychedelic (""mind-manifesting"") emphasizes that those who use these drugs as part of a therapeutic practice believe these drugs can facilitate beneficial exploration of the psyche. In contrast to conventional psychiatric medication which is taken by the patient regularly or as-needed, in psychedelic therapy, patients remain in an extended psychotherapy session during the acute activity of the drug and spend the night at the facility. In the sessions with the drug, therapists are nondirective and support the patient in exploring their inner experience. Patients participate in psychotherapy before the drug psychotherapy sessions to prepare them and after the drug psychotherapy to help them integrate their experiences with the drug.According to one Canadian study conducted in the early years of the 1960s, the greatest interest to the psychiatrist was the fact that LSD allowed for the ""illusional perception ('reperception') of the patient's original family figures (e.g. father, mother, parent surrogates and helpers, older siblings, grandparents and the like)"", typically experienced as distortions of the psychiatrist's face, body or activity. In technical terms, this was called ""perceptualizing the transference"".
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