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... and lichenification. Subjective measures included relief of pain, itching, or burning. Cloderm Cream statistically significantly out-performed its vehicle base in both objective and subjective measures at all time points. It is interesting to note, however, that there was an appreciable level of pat ...
Slides
Slides

...  A number of complex mechanisms may generate resistance to established chemotherapies, including taxanes ...
Probenecid
Probenecid

... Use with caution in patients with a history of peptic ulcer. The appearance of hypersensitivity reactions requires cessation of probenecid therapy. If probenecid is given with methotrexate, the dosage of methotrexate should be reduced and serum levels may need to be monitored. Haematuria, renal coli ...
DISCLAIMER STATEMENT
DISCLAIMER STATEMENT

... • an established treatment effect or historical evidence for sensitivity to drug effects (HESDE) was based on an overall clinical assessment; symptom-based improvements were included as part of the overall clinical assessment but were not described separately (cough, sputum production, chest pain, s ...
Inhaled formoterol  during  one  year  in ... a  comparison  with  salbutamol P.
Inhaled formoterol during one year in ... a comparison with salbutamol P.

... months there was a short period of deterioration of the asthma - probably due to a purulent bronchial infection - requiring acute asthma treatment. On the night before the six month dose-response test he became wheezy, and the FEV1 in the morning was considerably lower than betore. He showed a decre ...
New technologies and drugs in the management of diabetic
New technologies and drugs in the management of diabetic

... Intravitreal anti-VEGF therapy for DMO and PDR Pegaptanib was the first intravitreal anti-VEGF agent to be shown to be effective for DMO,45 and was quickly followed and replaced by bevacizumab,46 ranibizumab,47 and aflibercept48 as they became available and proved to be more clinically effective. On ...
Antimicrobial Treatment of Ventilator-Associated
Antimicrobial Treatment of Ventilator-Associated

... associated with increased mortality. This regimen must be selected before final microbiology results become known, but likely pathogens and antimicrobial resistance patterns can be predicted based on published guidelines, patient-specific factors, and local epidemiologic data. Nevertheless, the init ...
Basic concepts of Pharmacology. Pharmacokinetics of drugs.
Basic concepts of Pharmacology. Pharmacokinetics of drugs.

... 3. Interaction of drugs with specific receptors of biologically active substances. A role cyclic AMP, phosphoinositol and others secondary messengers in mechanisms of action of drugs. 4. The brief characteristic of the final pharmacological effects caused by drugs. 5. The characteristic local, refle ...
274   Antibacterials
274 Antibacterials

... in visual acuity that may be induced in children receiving ethambutol, the BNFC advises that it should be used with caution in children under 5 years of age and unable to report visual changes accurately, whereas in the USA licensed product information has advised against use in those under 13 years ...
Population Pharmacokinetics
Population Pharmacokinetics

...  Rapid maturation of organ functions important for drug absorption, distribution and elimination is a specific feature of very young paediatric patients, therefore changes in dose may be necessary for a patient over time, based on individual maturation.  Pharmacokinetic studies in the paediatric p ...
Ocular Side Effects of Sildenafil: A Prospective Study
Ocular Side Effects of Sildenafil: A Prospective Study

... Background: Sildenafil citrate (Viagra) is a drug commonly used for the treatment of impotence and pulmonary hypertension. There have been reports of adverse ocular side effects on the administration of these drugs. However, the reports are not consistent, and also very few studies have been done in ...
Insert Slide Title Here - Academy for Infection Management
Insert Slide Title Here - Academy for Infection Management

... • Tobias Welte ...
PRACTICAL THERAPEUTICS Drugs 45 (6): 918
PRACTICAL THERAPEUTICS Drugs 45 (6): 918

... Almost all studies have avoided a follow-up phase after completion of drug therapy, so the long term treatment outlook remains essentially unknown. A large number of studies have also lacked appropriate controls. In particular, a placebo group remains absolutely essential because otherwise there is ...
AVELOX PRODUCT INFORMATION
AVELOX PRODUCT INFORMATION

... warfarin, digoxin, probenecid, ranitidine, glyburide, iron, and antacids has been evaluated. No clinically significant drug-drug interactions were found with theophylline, warfarin, digoxin, probenecid, ranitidine or glibenclamide, but, as with all other quinolones, iron and antacids significantly r ...
Ulan Ude (Buryatia, Russia), 16
Ulan Ude (Buryatia, Russia), 16

... Fasting therapy developed by the Research Institute of Pulmonology was applied during 3 years at the Central district hospital on 14 patients with psoriasis (3 patients), neurodermitis (3 patients), eczema (4 patients), and . allergic dermatitis (4 patients). The former generally adopted therapy was ...
Charles T Costello and Arthur H Jeske 1995; 75:554-563. PHYS THER.
Charles T Costello and Arthur H Jeske 1995; 75:554-563. PHYS THER.

... aqueous solution, an inorganic compound dissociates into positively charged cations and negatively charged anions. When a direct electric current is passed through this solution, the cations move toward the negative electrode (the cathode) and the anions move toward the positive anode where the ion ...
Follow the Script_ Spring 2015
Follow the Script_ Spring 2015

... and is very safe when taken as prescribed. However, it’s a very potent drug and can be harmful if not used properly – even a little too much can be fatal – especially to children. This is why methadone is highly monitored and controlled. Methadone must be prescribed by a doctor and dispensed by a ph ...
Chelation in Metal Intoxication
Chelation in Metal Intoxication

... the evidence in the absence of the controlled trial is not as convincing. In view of reports where symptomatic improvements have been comparable with placebo effects and the risks associated with the therapy, it has been facing criticism [15]. The American Heart Association has stated that “there ha ...
Migraine prophylaxis - International Society of Drug Bulletins
Migraine prophylaxis - International Society of Drug Bulletins

... treatment worthIn the case of migraine, the answer is highly individualized. The drugs that are prescribed to prevent migraine attacks (as opposed to aborting attacks that occur) are not highly effective, and they have side effects. On the other hand, they have other indications, and if the patient ...
Managing Two Challenging Presentations of Acne
Managing Two Challenging Presentations of Acne

... women. Benzoyl peroxide is rated Category C but is nonetheless prescribed by some dermatologists for pregnant women. Other women may obtain the agent over-the-counter without seeking physician guidance. The apparent safety of topical erythromycin and clindamycin, both rated category B, make them att ...
ANTI-INFLAMMATORIES Alison Clode, DVM, DACVO Port City
ANTI-INFLAMMATORIES Alison Clode, DVM, DACVO Port City

... duration exists, with patients receiving oral prednisone at < 10 mg/day demonstrating an 11% incidence of cataract development, a 30% incidence with 10 – 15 mg/day doses, and 80% incidence with > 15 mg/day over 1 to 4 years.1 Additionally, children receiving corticosteroids will develop cataracts on ...
DMID 01-553 FQ EBA Study Results
DMID 01-553 FQ EBA Study Results

... • Can detect significant differences between drugs during the initial days of administration • Drugs can be compared with one another • Different doses can be evaluated to define dose for phase 2b & 3 trials • PK can be compared to bactericidal activity • Short term toxicity in humans with TB can be ...
outbreak of disease in kl: leptospirosis and h1n1
outbreak of disease in kl: leptospirosis and h1n1

... Chronic Obstructive Pulmonary Disease (COPD) is a disease state characterized by chronic irreversible airflow limitation. WHO estimated 210 million people has COPD worldwide and about 40 percent people has moderate to severe COPD. By year 2030, COPD is the third major cause of death. On March 2011, ...
Pan London Cytotoxic Policy
Pan London Cytotoxic Policy

... to. As some pregnancies are unplanned, or staff unwilling to discuss plans for conception, the emphasis must be on the reduction of exposure for all staff at all times. There have been some studies suggesting adverse effects on the foetus as a result of the mother working with cytotoxic drugs. Many ...
Clinical Practice Guidelines for the Management
Clinical Practice Guidelines for the Management

... It is estimated that the global burden of HIV-associated cryptococcosis approximates 1 million cases annually worldwide [11]. In medically developed countries, the modest burden of patients with cryptococcal disease persists, largely consisting of patients with newly diagnosed HIV infection; a growi ...
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Psychedelic therapy

Psychedelic therapy refers to therapeutic practices involving the use of psychedelic drugs, particularly serotonergic psychedelics such as LSD, psilocybin, DMT, mescaline, and 2C-B, primarily to assist psychotherapy. As an alternative to synonyms such as ""hallucinogen"", ""entheogen"", ""psychotomimetic"" and other functionally constructed names, the use of the term psychedelic (""mind-manifesting"") emphasizes that those who use these drugs as part of a therapeutic practice believe these drugs can facilitate beneficial exploration of the psyche. In contrast to conventional psychiatric medication which is taken by the patient regularly or as-needed, in psychedelic therapy, patients remain in an extended psychotherapy session during the acute activity of the drug and spend the night at the facility. In the sessions with the drug, therapists are nondirective and support the patient in exploring their inner experience. Patients participate in psychotherapy before the drug psychotherapy sessions to prepare them and after the drug psychotherapy to help them integrate their experiences with the drug.According to one Canadian study conducted in the early years of the 1960s, the greatest interest to the psychiatrist was the fact that LSD allowed for the ""illusional perception ('reperception') of the patient's original family figures (e.g. father, mother, parent surrogates and helpers, older siblings, grandparents and the like)"", typically experienced as distortions of the psychiatrist's face, body or activity. In technical terms, this was called ""perceptualizing the transference"".
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