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The Drug of War
The Drug of War

... this finding included the better pain management received by those administered ketamine, the neuronal protection provided by ketamine, and antagonism of the N-methyl-Daspartate (NMDA) receptor. Ketamine has also been considered in a recent review to be an ideal drug for use in many pre-hospital sit ...
High plasma linezolid concentration and impaired renal function
High plasma linezolid concentration and impaired renal function

... the latter having nearly 100% bioavailability,2 is expected to facilitate the treatment of infections caused by these organisms. In addition, linezolid has very favourable rates of penetration into tissues.3 This suggests a potential pharmacokinetic advantage of ...
60 - Glucocorticoid Therapy
60 - Glucocorticoid Therapy

... a lesser degree, albumin. Protein-bound cortisol is not biologically active, but the remaining 5% to 10% of free cortisol is. Prednisolone has—in contrast to methylprednisolone, dexamethasone, and triamcinolone—a high affinity for transcortin and competes with cortisol for this binding protein. The ...
Forensic Toxicology PPT
Forensic Toxicology PPT

... • The drug produces a sedative effect, amnesia, muscle relaxation, and a slowing of psychomotor responses. • Sedation occurs 20-30 minutes after administration and lasts for hours. • The drug is not commonly used by physicians in the US. • The drug has been added to drinks at parties, where it is re ...
Behavioral Profiles in Rats Distinguish Among “Ecstasy
Behavioral Profiles in Rats Distinguish Among “Ecstasy

... rodents (Pellow & File, 1986). The apparatus consisted of two black Plexiglas open arms (50 ⫻ 10 cm each), two closed arms (50 ⫻ 10 ⫻ 20 cm each) and a central platform (10 ⫻ 10 cm). The maze was elevated 70 cm above the floor. Each animal was placed at the center of the maze, facing one of the clos ...
I2326E-IF2326E- Savage NITROBID
I2326E-IF2326E- Savage NITROBID

... administered to a pregnant woman or whether it can affect reproductive capacity. Nitroglycerin should be given to a pregnant woman only if clearly needed. Nursing Mothers: It is not known whether nitroglycerin is excreted in human milk. Because many drugs are excreted in human milk, caution should b ...
YOUR INTERSTIM® THERAPY
YOUR INTERSTIM® THERAPY

... along to all of your health care provider appointments and share this information with doctors, dentists, MRI operators, and other health care professionals who may not be familiar with the InterStim Therapy system. Appendix B, Information for your doctors, on page 97, provides precautionary informa ...
Factors leading to PPI overuse Despite FDA alerts/concerns of PPI
Factors leading to PPI overuse Despite FDA alerts/concerns of PPI

... the long-term side effects to patients is lacking so education is imperative— something a pharmacist is trained to do. ...
Albumin and Furosemide Combination for Management of Edema in
Albumin and Furosemide Combination for Management of Edema in

... furosemide is less bound [4] to albumin and the free drug diffuses into the tissues with resultant increase in its volume of distribution. This results in less delivery to the proximal tubule for secretion into the lumen. In order to deliver a substantial amount of the drug to the proximal tubule, m ...
PA Criteria
PA Criteria

... patient has unresectable, locally advanced or metastatic disease. For LNETs: tumors are low or intermediate grade (typical or atypical carcinoid) and patient has unresectable or advanced disease (stage IIIb-IV). For breast cancer: 1) patient has hormone receptor positive, HER2-negative metastatic di ...
Reimbursement Support Request Form
Reimbursement Support Request Form

... • You should not take Ribasphere alone to treat chronic hepatitis C infection. • Ribasphere may cause you to have a blood problem (hemolytic anemia) that can worsen any heart problems you have, and cause you to have a heart attack or die. People with a history of serious heart disease should not b ...
Patient Registries and Participating in Clinical Trials
Patient Registries and Participating in Clinical Trials

... shortest period of time (this usually means testing better drugs and using biomarkers). • What is the rationale for excluding certain patients? Can those excluded be used in other ways? Parallel or compassionate studies? But remember that a patient can participate in only one trial at a time and tha ...
Association between KEGG Biological Pathways and Adverse Drug
Association between KEGG Biological Pathways and Adverse Drug

... Main factors play an important role in the development ADRs, some of these are patient related, drug related or socially related factors. Understanding the different effects of these factors on ADRs enables healthcare professionals to select the most appropriate medication for an individual [3]. Adv ...
biomedical aids research: recent and upcoming advances
biomedical aids research: recent and upcoming advances

... women (option B) in preventing mother-to-child transmission. Some concerns about drug toxicity emerged in this study, but these did not warrant any changes to current guidelines at this time. Linkage to and retention in care for pregnant women needs attention as the Global Plan towards the eliminati ...
Lithium Carbonate Extended-Release Tablets 300mg
Lithium Carbonate Extended-Release Tablets 300mg

... Safety and effectiveness in pediatric patients below the age of 12 have not been established (see WARNINGS). Geriatric Use Clinical studies of Lithium Carbonate Extended-Release Tablets did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from ...
Information for patients and healthcare providers
Information for patients and healthcare providers

... may lead to inhibition of bone growth in children and adolescents and the development of osteoporosis at any age. Special consideration should be given to patients at increased risk of osteoporosis (i.e., post-menopausal women) before initiating corticosteroid therapy. Neuro-psychiatric Although con ...
Pravachol
Pravachol

... PRAVACHOL is effective in reducing the risk of a fatal coronary event and non-fatal MI in patients with a previous myocardial infarction and average (normal) serum cholesterol, who are > 65 years of age and whose serum LDL-cholesterol is > 3.36 mmol/L. PRAVACHOL is effective in reducing the frequenc ...
A Practical Guide for Clinicians Who Treat Patients with Amiodarone
A Practical Guide for Clinicians Who Treat Patients with Amiodarone

... have been reported. The typical long-term side effects seen with oral amiodarone are seen rarely with acute IV dosing. Use in Pregnant Patients Amiodarone is not well-studied in pregnant patients. Amiodarone crosses the placental barrier, although fetal serum levels are only 10 –25% of maternal leve ...
highlights of prescribing information
highlights of prescribing information

... therapy. Refer to the prescribing information for ribavirin for additional information. Women of childbearing potential and men must use at least two forms of effective contraception during treatment and for at least 6 months after treatment has concluded. One of these forms of contraception can be ...
A - amphetamine
A - amphetamine

... BABE - drug used for detoxification BABY - marijuana BABY BHANG - marijuana BABY HABIT - occasional use of drugs BABYSIT - guide someone through first drug experience BABY T - crack BACK BREAKERS - LSD and strychnine BACK DEX - amphetamine BACKDOOR - residue left in a pipe BACKJACK - injecting opium ...
Daptomycyin Review
Daptomycyin Review

... doses up to 6 mg/kg in healthy volunteers.4 Plasma clearance is low, resulting in part from high protein binding (87–94%).32 Excretion of the drug occurs primarily via the kidney, with approximately 80% of the total dose, of which two-thirds is intact drug, recovered in the urine. There is low poten ...
etoposide injection usp
etoposide injection usp

... renal failure, pulmonary deterioration, thrombocytopenia, and ascites has been associated with an injectable vitamin E product containing polysorbate 80. Anaphylactic reactions have been reported in pediatric patients (see WARNINGS). Geriatric Use: Clinical studies of etoposide for the treatment of ...
Handbook 1108.1 Controlled Substances Pharmacy
Handbook 1108.1 Controlled Substances Pharmacy

... d. All prescriptions for controlled substances must be stamped with the letter “C,” in red ink, not less than 1 inch high, in the lower right corner, in accordance with 21 CFR 1304.04. NOTE: A waiver from this requirement is identified in 21 CFR 1304.04, if the pharmacy uses an automated system. e. ...
Efficacy of Intravitreal Bevacizumab for Stage 3+
Efficacy of Intravitreal Bevacizumab for Stage 3+

... without masking of treatment assignments, before deciding on additional treatment. Cases requiring additional treatment consisting of a few laser applications to inadvertently skipped areas within 1 week after initial treatment were not considered to be recurrences. In addition, we took RetCam photo ...
Research Quarterly
Research Quarterly

... on co-occurring PTSD and substance use disorder is very limited. Peer-reviewed reports are typically of pilot projects designed to develop initial feasibility and palatability of the treatment. The iterative process of psychotherapy development is often neglected in these reports, so it is difficult ...
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Psychedelic therapy

Psychedelic therapy refers to therapeutic practices involving the use of psychedelic drugs, particularly serotonergic psychedelics such as LSD, psilocybin, DMT, mescaline, and 2C-B, primarily to assist psychotherapy. As an alternative to synonyms such as ""hallucinogen"", ""entheogen"", ""psychotomimetic"" and other functionally constructed names, the use of the term psychedelic (""mind-manifesting"") emphasizes that those who use these drugs as part of a therapeutic practice believe these drugs can facilitate beneficial exploration of the psyche. In contrast to conventional psychiatric medication which is taken by the patient regularly or as-needed, in psychedelic therapy, patients remain in an extended psychotherapy session during the acute activity of the drug and spend the night at the facility. In the sessions with the drug, therapists are nondirective and support the patient in exploring their inner experience. Patients participate in psychotherapy before the drug psychotherapy sessions to prepare them and after the drug psychotherapy to help them integrate their experiences with the drug.According to one Canadian study conducted in the early years of the 1960s, the greatest interest to the psychiatrist was the fact that LSD allowed for the ""illusional perception ('reperception') of the patient's original family figures (e.g. father, mother, parent surrogates and helpers, older siblings, grandparents and the like)"", typically experienced as distortions of the psychiatrist's face, body or activity. In technical terms, this was called ""perceptualizing the transference"".
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