Sudden unexpected death in epilepsy
... Mortality in people with epilepsy is two- to three-times that of the general population. This can be attributed to epilepsy itself (epilepsy-related death) or to the underlying cause of the epilepsy. Sudden unexpected death in epilepsy (SUDEP) is the commonest cause of epilepsy-related death. It is ...
... Mortality in people with epilepsy is two- to three-times that of the general population. This can be attributed to epilepsy itself (epilepsy-related death) or to the underlying cause of the epilepsy. Sudden unexpected death in epilepsy (SUDEP) is the commonest cause of epilepsy-related death. It is ...
AASLD PRACTICE GUIDELINE UPDATE Chronic Hepatitis B
... 30% in infants and children under 5 and to less than 5% in adults.20-24 In addition, immunosuppressed persons are more likely to develop chronic HBV infection after acute infection.25,26 In countries such as the United States where most of the infants, children, and adolescents have been vaccinated ...
... 30% in infants and children under 5 and to less than 5% in adults.20-24 In addition, immunosuppressed persons are more likely to develop chronic HBV infection after acute infection.25,26 In countries such as the United States where most of the infants, children, and adolescents have been vaccinated ...
Product Monograph Template - Standard - GlaxoSmithKline
... • The dosage of ZOVIRAX® (acyclovir) should be reduced in patients with impaired renal function. • Therapy should be initiated as soon as possible after a diagnosis of chickenpox or herpes zoster, or at the first sign or symptoms of an outbreak of genital herpes. • The recommended dose and duration ...
... • The dosage of ZOVIRAX® (acyclovir) should be reduced in patients with impaired renal function. • Therapy should be initiated as soon as possible after a diagnosis of chickenpox or herpes zoster, or at the first sign or symptoms of an outbreak of genital herpes. • The recommended dose and duration ...
The Selection and Use of Essential Medicines
... health matters and public health. One of WHO’s constitutional functions is to provide objective and reliable information and advice in the field of human health, a responsibility that it fulfils in part through its extensive programme of publications. The Organization seeks through its publications ...
... health matters and public health. One of WHO’s constitutional functions is to provide objective and reliable information and advice in the field of human health, a responsibility that it fulfils in part through its extensive programme of publications. The Organization seeks through its publications ...
Mannitol dry powder for inhalation for treating cystic fibrosis
... analyses did not include the primary outcome, absolute FEV1, but instead were FEV1% predicted, the proportion responding according to FEV1 criteria, and the estimated rate of PDPE per patient per year. For the pooled adult population of people using rhDNase, the mean change in FEV1 over 26 weeks for ...
... analyses did not include the primary outcome, absolute FEV1, but instead were FEV1% predicted, the proportion responding according to FEV1 criteria, and the estimated rate of PDPE per patient per year. For the pooled adult population of people using rhDNase, the mean change in FEV1 over 26 weeks for ...
Guidelines on the use of extracorporeal photopheresis
... at more than 200 centres worldwide.1 During ECP, the patient’s whole blood is processed outside the body: blood is collected via an ante-cubital vein, or via a permanent catheter if access is cumbersome, and the white blood cells are separated from the red blood cells and plasma by centrifugation in ...
... at more than 200 centres worldwide.1 During ECP, the patient’s whole blood is processed outside the body: blood is collected via an ante-cubital vein, or via a permanent catheter if access is cumbersome, and the white blood cells are separated from the red blood cells and plasma by centrifugation in ...
8 - Circulation
... The maintenance serum amiodarone concentrations during long-term therapy were 0.4-3.3 mg/l (mean 1.7 mg/l) in the 122 patients. Immediately after prolonged high-dose oral loading, concentrations of up to 6.7 mg/l were recorded, especially early in the study. When this occurred the maintenance dose w ...
... The maintenance serum amiodarone concentrations during long-term therapy were 0.4-3.3 mg/l (mean 1.7 mg/l) in the 122 patients. Immediately after prolonged high-dose oral loading, concentrations of up to 6.7 mg/l were recorded, especially early in the study. When this occurred the maintenance dose w ...
PhVWP BEST PRACTICE GUIDE FOR WORK SHARING
... times a day yielded a significant increase in cisapride plasma levels and prolongation of QT interval. Concomitant treatment with fluconazole and cisapride is contraindicated (see section 4.3 Contraindications). Terfenadine: Because of the occurrence of serious cardiac dysrhythmias secondary to prol ...
... times a day yielded a significant increase in cisapride plasma levels and prolongation of QT interval. Concomitant treatment with fluconazole and cisapride is contraindicated (see section 4.3 Contraindications). Terfenadine: Because of the occurrence of serious cardiac dysrhythmias secondary to prol ...
Generalized Pustular Psoriasis of Zambusch: Case Report of Successful
... psoriasis that was unresponsive to prior therapy. They found that etanercept provided safe, effective, and durable results, and suggested that it should be considered for the management of patients with severe treatment-resistant pustular psoriasis.13 Unlike etanercept, cyclosporine is a T-cell inhi ...
... psoriasis that was unresponsive to prior therapy. They found that etanercept provided safe, effective, and durable results, and suggested that it should be considered for the management of patients with severe treatment-resistant pustular psoriasis.13 Unlike etanercept, cyclosporine is a T-cell inhi ...
Data Analytics with SNOMED CT â Case Studies
... SNOMED CT is widely recognized as the leading global clinical terminology for use in Electronic Health Records (EHRs). SNOMED CT is used within EHRs to support data capture, retrieval, and subsequent reuse for a wide range of purposes, from patient-based queries to operational reporting, public heal ...
... SNOMED CT is widely recognized as the leading global clinical terminology for use in Electronic Health Records (EHRs). SNOMED CT is used within EHRs to support data capture, retrieval, and subsequent reuse for a wide range of purposes, from patient-based queries to operational reporting, public heal ...
MHRA recommendations on simvastatin interactions: What are the
... that can increase the risk of myopathy and/or rhabdomyolysis. When used with amlodipine, the maximum dose of simvastatin is now 20mg; higher doses are ‘off-label’. For patients taking amlodipine and simvastatin 40mg consider: 1. Reducing simvastatin dose to 20mg–most patients can be managed this way ...
... that can increase the risk of myopathy and/or rhabdomyolysis. When used with amlodipine, the maximum dose of simvastatin is now 20mg; higher doses are ‘off-label’. For patients taking amlodipine and simvastatin 40mg consider: 1. Reducing simvastatin dose to 20mg–most patients can be managed this way ...
Myeloma Matters vol 8 issue 3
... To help improve our understanding of fatigue Myeloma UK carried out a survey in over 100 myeloma patients. In comparison to other symptoms of myeloma and side-effects of its treatment, patients surveyed ranked fatigue as the most challenging to live with. In total, 88% of respondents found that fati ...
... To help improve our understanding of fatigue Myeloma UK carried out a survey in over 100 myeloma patients. In comparison to other symptoms of myeloma and side-effects of its treatment, patients surveyed ranked fatigue as the most challenging to live with. In total, 88% of respondents found that fati ...
Prescribing Information REYATAZ TM 150 mg REYATAZ TM 200 mg
... If unable to tolerate ritonavir, administer REYATAZ 400 mg once daily at least 2 hours before and at least 10 hours after the H2-receptor antagonist. No single dose of the H2-receptor antagonist should exceed a dose comparable to famotidine 20 mg and the total daily dose should not exceed a dose com ...
... If unable to tolerate ritonavir, administer REYATAZ 400 mg once daily at least 2 hours before and at least 10 hours after the H2-receptor antagonist. No single dose of the H2-receptor antagonist should exceed a dose comparable to famotidine 20 mg and the total daily dose should not exceed a dose com ...
Annex I: Final CSP Fluconazol 4.3 Contraindications Fluconazole
... mg for 14 days resulted in an 18% decrease in the mean plasma clearance rate of theophylline. Patients who are receiving high dose theophylline or who are otherwise at increased risk for theophylline toxicity should be observed for signs of theophylline toxicity while receiving fluconazole. Therapy ...
... mg for 14 days resulted in an 18% decrease in the mean plasma clearance rate of theophylline. Patients who are receiving high dose theophylline or who are otherwise at increased risk for theophylline toxicity should be observed for signs of theophylline toxicity while receiving fluconazole. Therapy ...
... in lung function 3 min after inhalation, compared with salmeterol. With comparison to placebo, salmeterol also produced an improvement in lung function 3 min after inhalation. Fifteen min after inhalation, the effect of salmeterol 50 µg approached the effects of the lowest dose of formoterol. It cou ...
These highlights do not include all the information needed to use Kit
... Myocardial Imaging: Technetium Tc 99m Sestamibi Injection is a myocardial perfusion agent that is indicated for detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and infarction (non-reversible defects), in evaluating myocardial function and developing informati ...
... Myocardial Imaging: Technetium Tc 99m Sestamibi Injection is a myocardial perfusion agent that is indicated for detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and infarction (non-reversible defects), in evaluating myocardial function and developing informati ...
Trauma Association of Canada Annual Scientific Meeting
... cost analysis of patients with burn or inhalation injuries due to residential fires, and to compare this to the cost of implementing residential automatic fire sprinklers. Methods: We conducted a cohort analysis of adult burn patients admitted to our provincial burn centre (1995–2012). Patient demog ...
... cost analysis of patients with burn or inhalation injuries due to residential fires, and to compare this to the cost of implementing residential automatic fire sprinklers. Methods: We conducted a cohort analysis of adult burn patients admitted to our provincial burn centre (1995–2012). Patient demog ...
Chapter 12: Emergency Medications
... • Animal studies have not demonstrated a fetal risk but there are no controlled studies in women or • Animal reproductive studies have shown an adverse effect that was not confirmed in controlled studies on women in the first trimester ...
... • Animal studies have not demonstrated a fetal risk but there are no controlled studies in women or • Animal reproductive studies have shown an adverse effect that was not confirmed in controlled studies on women in the first trimester ...
COMP Minutes 19-21 January 2016 - EMA
... asked to compare and contrast the new definition of the disease versus the classic classification of the disease. Specifically, the sponsor should discuss the aetiopathogenesis of the proposed condition and how it is reflected by both definitions. To establish correctly if there exists a scientific ...
... asked to compare and contrast the new definition of the disease versus the classic classification of the disease. Specifically, the sponsor should discuss the aetiopathogenesis of the proposed condition and how it is reflected by both definitions. To establish correctly if there exists a scientific ...
CIPRO
... Special Populations: Pharmacokinetic studies of the oral (single dose) and intravenous (single and multiple dose) forms of ciprofloxacin indicate that plasma concentrations of ciprofloxacin are higher in elderly subjects (> 65 years) as compared to young adults. Although the Cmax is increased 16-40% ...
... Special Populations: Pharmacokinetic studies of the oral (single dose) and intravenous (single and multiple dose) forms of ciprofloxacin indicate that plasma concentrations of ciprofloxacin are higher in elderly subjects (> 65 years) as compared to young adults. Although the Cmax is increased 16-40% ...
Angioedema In The Emergency Department: An Evidence-Based Review November 2012
... respiratory or gastrointestinal tracts. It is now generally accepted that the swelling is mediated by either histamine or bradykinin. Angioedema may result in severe upper airway compromise or—less commonly recognized—compromise in the gastrointestinal tract often associated with severe abdominal pa ...
... respiratory or gastrointestinal tracts. It is now generally accepted that the swelling is mediated by either histamine or bradykinin. Angioedema may result in severe upper airway compromise or—less commonly recognized—compromise in the gastrointestinal tract often associated with severe abdominal pa ...
Biologics for Psoriasis and Psoriatic Arthritis – Monograph with Literature Review
... reviews showed that adalimumab, etanercept and infliximab were similar in efficacy; another showed infliximab to be most effective overall (for joint and skin outcomes), etanercept better than adalimumab for joint outcomes, and adalimumab to be better than etanercept for skin outcomes; and a third r ...
... reviews showed that adalimumab, etanercept and infliximab were similar in efficacy; another showed infliximab to be most effective overall (for joint and skin outcomes), etanercept better than adalimumab for joint outcomes, and adalimumab to be better than etanercept for skin outcomes; and a third r ...
Implications of Recent Clinical Trials for the National Cholesterol
... changes (TLC) as an essential modality in clinical management for persons at risk for cardiovascular disease (CVD). ATP III’s TLC approach was designed to achieve risk reduction through both LDL-C lowering and metabolic syndrome management. Therefore, when the implications of recent LDL-lowering dru ...
... changes (TLC) as an essential modality in clinical management for persons at risk for cardiovascular disease (CVD). ATP III’s TLC approach was designed to achieve risk reduction through both LDL-C lowering and metabolic syndrome management. Therefore, when the implications of recent LDL-lowering dru ...
UK guidelines for the management of Stevens
... SJS/TEN is rare and few healthcare professionals are confident in the recognition and management of the disorder. There is widely divergent practice among different specialities and healthcare settings, and limited information on outcomes. These guidelines aim to provide recommendations on the diagn ...
... SJS/TEN is rare and few healthcare professionals are confident in the recognition and management of the disorder. There is widely divergent practice among different specialities and healthcare settings, and limited information on outcomes. These guidelines aim to provide recommendations on the diagn ...