Insoluble and soluble immune complexes activate neutrophils by
... failed to activate unprimed neutrophils but generated a rapid and extensive secretion of reactive oxygen metabolites when the cells were primed with granulocyte-macrophage colony stimulating factor (GM-CSF). This activity required both FcγRII and FcγRIIIb function. Insoluble immune complexes activat ...
... failed to activate unprimed neutrophils but generated a rapid and extensive secretion of reactive oxygen metabolites when the cells were primed with granulocyte-macrophage colony stimulating factor (GM-CSF). This activity required both FcγRII and FcγRIIIb function. Insoluble immune complexes activat ...
Intracellular Localization of Interleukin-6 in
... OSINOPHILS, prominent cells in allergic inflammation and asthma, have been shown to synthesize, store, and release up to 18 inflammatory and regulatory cytokines and growth factors,1 including interleukin-2 (IL-2), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor (GM-CSF).2-5 We have ...
... OSINOPHILS, prominent cells in allergic inflammation and asthma, have been shown to synthesize, store, and release up to 18 inflammatory and regulatory cytokines and growth factors,1 including interleukin-2 (IL-2), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor (GM-CSF).2-5 We have ...
Pathogen-Induced Apoptotic Neutrophils Express Heat
... apoptosis in neutrophils represents a pathogenic strategy for microbes to eliminate these key immune cells and use them as “Trojan horses” to enter M. However, in the cited studies, neutrophil apoptosis was induced by age or irradiation; thus, the results may not apply to the very early phase of in ...
... apoptosis in neutrophils represents a pathogenic strategy for microbes to eliminate these key immune cells and use them as “Trojan horses” to enter M. However, in the cited studies, neutrophil apoptosis was induced by age or irradiation; thus, the results may not apply to the very early phase of in ...
Strategies of professional phagocytes in vivo
... The early control of potentially invading microbes by our immune system primarily depends on its main professional phagocytes – macrophages and neutrophils. Although the different functions of these two cell types have been extensively studied, little is known about their respective contributions to ...
... The early control of potentially invading microbes by our immune system primarily depends on its main professional phagocytes – macrophages and neutrophils. Although the different functions of these two cell types have been extensively studied, little is known about their respective contributions to ...
Journal of Otology & Rhinology
... breakage of the upper airway. Many researchers have demonstrated that ROS can have a variety of physiological and deleterious effects within the airway [1]. It appears that ROS may participate in various diseases including those of the nose, although many details are not yet known. ROS is a general ...
... breakage of the upper airway. Many researchers have demonstrated that ROS can have a variety of physiological and deleterious effects within the airway [1]. It appears that ROS may participate in various diseases including those of the nose, although many details are not yet known. ROS is a general ...
... The association between helminthic infestation and peripheral blood eosinophilia dates back to the beginning of this century, and frequently involves the lung (tropical filarial eosinophilia) [359]. Four main findings have emerged over the past two decades. Firstly, antieosinophil serum reduces both ...
Neutrophils in tuberculosis
... Tuberculosis is a devastating disease throughout the world both in humans and animals. Its history is vast, which dates back to era of Robert Koch. There is a huge amount of immunological studies in the aspect of tuberculosis but there remain many unanswered questions. Neutrophils, cells of First li ...
... Tuberculosis is a devastating disease throughout the world both in humans and animals. Its history is vast, which dates back to era of Robert Koch. There is a huge amount of immunological studies in the aspect of tuberculosis but there remain many unanswered questions. Neutrophils, cells of First li ...
Neutrophils diminish T-cell immunity to foster gastric cancer
... of proteinases and inflammatory factors that directly promote tumour cell proliferation, such as neutrophil elastase, prostaglandin E2 and interleukin-1 β (IL-1β).8 9 Neutrophils can also promote tumour growth by regulating the tumour microenvironment.10 Neutrophils are suggested to share similaritie ...
... of proteinases and inflammatory factors that directly promote tumour cell proliferation, such as neutrophil elastase, prostaglandin E2 and interleukin-1 β (IL-1β).8 9 Neutrophils can also promote tumour growth by regulating the tumour microenvironment.10 Neutrophils are suggested to share similaritie ...
Arachidonic acid mobilization by stimuli of the innate immune
... acid. In cells, AA seldom occurs in free fatty acid form, and is almost always found esterified at the sn-2 position of glycerophospholipids. Thus, it has to be removed from there before any eicosanoid synthesis can occur. The enzymes involved in such a removal are the phospholipase A2s (PLA2s). The ...
... acid. In cells, AA seldom occurs in free fatty acid form, and is almost always found esterified at the sn-2 position of glycerophospholipids. Thus, it has to be removed from there before any eicosanoid synthesis can occur. The enzymes involved in such a removal are the phospholipase A2s (PLA2s). The ...