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Warfarin Dosing Guideline 2009
Warfarin Dosing Guideline 2009

... Warfarin should be dosed to achieve the desired target INR based on indication (1,2). Patients with significant drug interactions should be initiated at a lower dose (1). There is no evidence to support “loading doses” of warfarin as this has been demonstrated to lead to supratherapeutic INRs and an ...
ICU SEDATION GUIDELINES - Surgical Critical Care. Net
ICU SEDATION GUIDELINES - Surgical Critical Care. Net

... Warfarin should be dosed to achieve the desired target INR based on indication (1,2). Patients with significant drug interactions should be initiated at a lower dose (1). There is no evidence to support “loading doses” of warfarin as this has been demonstrated to lead to supratherapeutic INRs and an ...
Form versus disease: optimizing geometry during ventricular
Form versus disease: optimizing geometry during ventricular

... score, ejection fraction, and LVESVI improve if initial LVESVI is <75 ml/m2, but progressively deteriorate when preoperative LVESVI is >75 ml/m2, despite open grafts [8]. The spherical geometry of the globally hypokinetic dilated heart resembles the shape changes noted with extensive scar. Malfuncti ...
The CopenHeartSF trial-comprehensive sexual rehabilitation programme for male patients
The CopenHeartSF trial-comprehensive sexual rehabilitation programme for male patients

... Sexuality is an important part of people’s physical and mental health.1 2 Patients with cardiovascular disease have an increased prevalence of sexual dysfunction.3–5 The causes of sexual dysfunction can be related to physical changes due to the disease, mental changes or adverse reactions to drugs a ...
06. Heart failure
06. Heart failure

... •Patients with New York Heart Association Classification IV who have failed medical therapy ...
Chapter 21 An Introduction to Blood Vessels and Circulation 21
Chapter 21 An Introduction to Blood Vessels and Circulation 21

... • Direct capillary connections between arterioles and venules • Controlled by smooth muscle segments (metarterioles) ...
Myxomatous mitral valve disease in dogs
Myxomatous mitral valve disease in dogs

... most of these studies. Prevalence was strongly associated with breed, age and body size (1, 5). This disease is very rare in cats, although the actual prevalence in this species is not known. Natural history of the disease The disease is characterized by a systolic murmur at the mitral area, which i ...
essential agents in management of heart failure.
essential agents in management of heart failure.

... 20-40% of all heart failure patients have normal ejection fractions! (it is likely that majority of elderly heart failure patients have primarily diastolic dysfunction). ● mortality rates are lower than with low ejection fractions (however, hospitalization rates are comparable). ● non-invasive measu ...
Heart failure
Heart failure

... NYHA Classification of HF Class I —No limitation: Ordinary physical activity does not cause undue fatigue, dyspnea, or palpitation. Class II —Slight limitation of physical activity: Such patients are comfortable at rest.Ordinary physical activity results in fatigue, palpitation dyspnea, or angina. ...
NON-VALVULAR ATRIAL FIBRILLATION AND STROKE
NON-VALVULAR ATRIAL FIBRILLATION AND STROKE

... Can Stroke be Prevented in NVAF? This question has been addressed by five studies 17-21; comparing warfarin, aspirin and placebo. All have been terminated early, within two years, because the warfarin group had shown significant benefit and it was considered unethical to continue the trials. The ave ...
Contributing Factors Of Determining Multiple And Underlying Cause
Contributing Factors Of Determining Multiple And Underlying Cause

... Similarly, descriptive statistics including total numbers and proportions will be presented for the two sub-populations with ischemic heart disease (n=79,833) or diabetes mellitus (n=27,181) mentioned either as underlying or a contributing cause of death on the death certificates. Logistic regressio ...
Long Term Anti-Coagulants (LTAC)
Long Term Anti-Coagulants (LTAC)

... – No Date – Pulmonary Embolus – Pulmonary Hypertension – University of California San Diego – Vitamin K Antagonist ...
Effect of Low-Energy Diets Differing in Fiber, Red Meat, and Coffee
Effect of Low-Energy Diets Differing in Fiber, Red Meat, and Coffee

... system is a key player linking the development and progression of cardiovascular disease with obesity (5). Cardiac sympathovagal imbalance, estimated by the low-frequency/high-frequency ratio, which is characterized by a shift toward sympathetic predominance and diminished vagal activity, is a conse ...
Ct Of The Heart
Ct Of The Heart

... cardiac ct scan nhlbi nih - a cardiac ct scan is a painless imaging test that uses x rays to take many detailed pictures of your heart and its blood vessels, heart ct scan medlineplus medical encyclopedia - a computed tomography ct scan of the heart is an imaging method that uses x rays to create de ...
Introduction - YorkSpace
Introduction - YorkSpace

... potential benefits of screening and investigate treatments is needed. ...
Acute Myocardial Infarction with Simultaneous Occlusions of Left
Acute Myocardial Infarction with Simultaneous Occlusions of Left

... Acute myocardial infarctions involving multiple coronary arteries simultaneously are infrequent and causative risk factors of the occlusions are unclear. However, severe complications arise, such as congestive heart failure or death. We report a case of two simultaneously occluded coronary arteries. ...
view a sample chapter
view a sample chapter

... There are four valves in the heart. The two atrioventricular (AV) valves separate the atria and the ventricles. The right AV valve is the tricuspid; the left AV valve is the bicuspid, or mitral, valve. The AV valves open during the heart’s filling phase, or diastole, to allow the ventricles to fill ...
Transposition of the Great Arteries
Transposition of the Great Arteries

... B. Normal development of ventricular situs (Moore, 2008) 1. Occurs during the 5th week of gestation 2. Twisting of the primordial heart tube to right (d-looping) a. Places eventual morphologic right ventricle on right side of heart b. Places eventual morphologic left ventricle on left side of heart ...
Chronic Ischemic Heart Disease
Chronic Ischemic Heart Disease

... For reasons that are unclear, some patients with chronic ischemic heart disease do not manifest typical symptoms of angina pectoris but have other symptoms that are brought on by the same precipitating factors and are relieved in the same way as angina. Because myocardial ischemia can lead to transi ...
8) Takanobu Okamoto, Mitsuhiko Masuhara, Komei Ikuta
8) Takanobu Okamoto, Mitsuhiko Masuhara, Komei Ikuta

... at rest and during sub-maximal exercise in normo-tensive and hypertensive individuals . 3 Based on oxygen utility exercise can be classified into aerobic (endurance Exercise) or anaerobic ( resistance training) . 4 Aerobic exercise refers to any exercise that uses large muscle groups continuous and ...
Serpentine Coronary Arteries
Serpentine Coronary Arteries

... and aortic regurgitation, tortuosity was more common in women and was more pronounced in patients with chronic pressure than in those with volume overload. The determinants of coronary tortuosity were sex, age, LV volume, and muscle mass.3 Our patient had 2 significant conditions that caused increas ...
Long term survival study of patients with raised pulmonary arterial
Long term survival study of patients with raised pulmonary arterial

... approach to diagnosis is of vital importance, as they are less likely to tolerate multiple tests. There is also a potential for escalating costs arising from pursuing a number of abnormal initial tests. Our study, however, suggests that additional clinical assessments should be considered for indivi ...
A case of biventricular endomyocardial fibrosis complicated by right
A case of biventricular endomyocardial fibrosis complicated by right

... flouroscopy.[5,6] This feature was present in this case. The presence of focal, tubular aneurysms of the RVOT, however, is unique. These may have arisen owing to high RV diastolic pressures related to reduced RV volume, decreased RV compliance and poor RV relaxation. The RVOT is the most likely regi ...
Cardiac Cycle - Sonoma Valley High School
Cardiac Cycle - Sonoma Valley High School

... – Increased levels of K+ & Na+ slow heart rate. – Excess Ca++ increases heart rate. – Low oxygen demands increase heart rate. ...
The Effect of Exertional Hypertension Evoked by Weight
The Effect of Exertional Hypertension Evoked by Weight

... To the Editor: Chronic hypertension is associated with arterial endothelial dysfunction, the precursor to atherosclerosis (1); however, less is known about the effects of brief episodes of hypertension on endothelial function. Lamping and Dole (2) demonstrated that ⬍5 min of moderate elevations in p ...
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Cardiovascular disease



Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. Cardiovascular disease includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs are stroke, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, atrial fibrillation, congenital heart disease, endocarditis, aortic aneurysms, peripheral artery disease and venous thrombosis.The underlying mechanisms vary depending on the disease in question. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, among others. High blood pressure results in 13% of CVD deaths, while tobacco results in 9%, diabetes 6%, lack of exercise 6% and obesity 5%. Rheumatic heart disease may follow untreated strep throat.It is estimated that 90% of CVD is preventable. Prevention of atherosclerosis is by decreasing risk factors through: healthy eating, exercise, avoidance of tobacco smoke and limiting alcohol intake. Treating high blood pressure and diabetes is also beneficial. Treating people who have strep throat with antibiotics can decrease the risk of rheumatic heart disease. The effect of the use of aspirin in people who are otherwise healthy is of unclear benefit. The United States Preventive Services Task Force recommends against its use for prevention in women less than 55 and men less than 45 years old; however, in those who are older it is recommends in some individuals. Treatment of those who have CVD improves outcomes.Cardiovascular diseases are the leading cause of death globally. This is true in all areas of the world except Africa. Together they resulted in 17.3 million deaths (31.5%) in 2013 up from 12.3 million (25.8%) in 1990. Deaths, at a given age, from CVD are more common and have been increasing in much of the developing world, while rates have declined in most of the developed world since the 1970s. Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. Most cardiovascular disease affects older adults. In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80, and 85% of people over 80 have CVD. The average age of death from coronary artery disease in the developed world is around 80 while it is around 68 in the developing world. Disease onset is typically seven to ten years earlier in men as compared to women.
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