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... diagnosed if the patient has six or more symptoms. People who have anxiety, bipolar disorder, depression, psychosis, or another substance use disorder are at risk for developing tobacco use disorder.5,18,19 There is evidence of an inherited trait that can predispose someone to the development of tob ...
... diagnosed if the patient has six or more symptoms. People who have anxiety, bipolar disorder, depression, psychosis, or another substance use disorder are at risk for developing tobacco use disorder.5,18,19 There is evidence of an inherited trait that can predispose someone to the development of tob ...
Habitrol Chewing Gum
... No animal studies have been undertaken on Habitrol Chewing Gum. The toxicity of nicotine as a constituent of tobacco has been well documented. Acute toxic effects include convulsions, cardiac insufficiency, and paralysis of the respiratory system. In cats and dogs, nicotine at high doses has been sh ...
... No animal studies have been undertaken on Habitrol Chewing Gum. The toxicity of nicotine as a constituent of tobacco has been well documented. Acute toxic effects include convulsions, cardiac insufficiency, and paralysis of the respiratory system. In cats and dogs, nicotine at high doses has been sh ...
Case Report Postmortem Distribution of Nicotine and Cotinine from
... Journal of Analytical Toxicology,Vol. 21, July/August1997 7. R.C. Baselt and R.H. Cravey. Disposition of Toxic Drugs and Chemicals in Man, 4th ed. Chemical Toxicology Institute, Foster ...
... Journal of Analytical Toxicology,Vol. 21, July/August1997 7. R.C. Baselt and R.H. Cravey. Disposition of Toxic Drugs and Chemicals in Man, 4th ed. Chemical Toxicology Institute, Foster ...
Anti-Infective Agents
... • Within 10 to 20 seconds of a single puff from a cigarette, nicotine attaches to this receptor. • The receptor, in turn, triggers large increases in dopamine, which rewards the smoker with a pleasurable sensation. ...
... • Within 10 to 20 seconds of a single puff from a cigarette, nicotine attaches to this receptor. • The receptor, in turn, triggers large increases in dopamine, which rewards the smoker with a pleasurable sensation. ...
Nicotine
Nicotine is a potent parasympathomimetic alkaloid found in the nightshade family of plants (Solanaceae) and is a stimulant drug. Nicotine is a nicotinic acetylcholine receptor (nAChR) agonist, (a Na⁺/K⁺ ionophore through neural postsynaptic membranes in mammals and insects) except at nAChRα9 and nAChRα10 where it acts as an antagonist. It is made in the roots of and accumulates in the leaves of the nightshade family of plants. Nicotine is found in the leaves of Nicotiana tabacum, the tobacco plant, and Nicotiana rustica in amounts of 2–14 %, as well as in Duboisia hopwoodii and Asclepias syriaca.It constitutes approximately 0.6–3.0% of the dry weight of tobacco and is present in the range of 2–7 µg/kg of various edible plants. It functions as an antiherbivore chemical; consequently, nicotine was widely used as an insecticide in the pastand neonicotinoids such as imidacloprid are currently widely used.In lesser doses (an average cigarette yields about 2 mg of absorbed nicotine), the substance acts as a stimulant in mammals, while high amounts (50–100 mg) can be harmful.This stimulant effect is the major contributing factor to the addictive properties of tobacco smoking. Nicotine is associated with cardiovascular disease, potential birth defects, and poisoning. Laboratory studies have associated it with cancer, but nicotine outside tobacco has not been shown to be associated with cancer in the real world.