Polypoid melanoma - Our Dermatology Online journal
... Traditionally, it has been considered to be part of the nodular melanoma spectrum, however, it may also arise from the acrolentiginous, superficial spreading and lentigo maligna types, displaying a growth pattern restricted to the papillary dermis [6]. Since the tumor typically does not penetrate de ...
... Traditionally, it has been considered to be part of the nodular melanoma spectrum, however, it may also arise from the acrolentiginous, superficial spreading and lentigo maligna types, displaying a growth pattern restricted to the papillary dermis [6]. Since the tumor typically does not penetrate de ...
On laboratory investigations, complete blood count, ESR, serum
... Introduction Lupus miliaris disseminatus faciei (LMDF), is a rare skin disease that usually occurs in young adults of either gender.1-3 It presents as discrete, symmetrical, reddish-brown to pink, dome-shaped papules on the face and elsewhere.1-3 This eruption tends to be self-limiting, resolving co ...
... Introduction Lupus miliaris disseminatus faciei (LMDF), is a rare skin disease that usually occurs in young adults of either gender.1-3 It presents as discrete, symmetrical, reddish-brown to pink, dome-shaped papules on the face and elsewhere.1-3 This eruption tends to be self-limiting, resolving co ...
Topical Tazarotene Chemoprevention Reduces Basal Cell
... background genetic variation in this mouse population (i.e., mixed C57BL/6 and DBA/2J strain). Supporting this, our recent studies show that inbred Ptch1⫹/⫺ mice exposed once to IR had significantly less variation of BCC number and size than did mice of more variable genetic background.7 Tazarotene ...
... background genetic variation in this mouse population (i.e., mixed C57BL/6 and DBA/2J strain). Supporting this, our recent studies show that inbred Ptch1⫹/⫺ mice exposed once to IR had significantly less variation of BCC number and size than did mice of more variable genetic background.7 Tazarotene ...
an analysis of skin appendageal tumors in south india.
... Histologically, all of them showed horncyst surrounded by basophilic cells showing Trichilemmal keratinisation, except for one case where there was no horn cyst formation. Islands of basophilic cells show peripheral pallisading. Important histopathological differential diagnosis is Basal Cell Carcin ...
... Histologically, all of them showed horncyst surrounded by basophilic cells showing Trichilemmal keratinisation, except for one case where there was no horn cyst formation. Islands of basophilic cells show peripheral pallisading. Important histopathological differential diagnosis is Basal Cell Carcin ...
Glomangioma: Rare Localization of a Rare Skin Tumor
... did not receive any diagnosis. Since 2 years, the leg pain increased and became resistant to analgesics and intolerant to his clothes. His motor and sensory examination was found to be normal. His Straight Leg Raise (SLR) was negative. There was “point hyperesthesia” in a localized area. His physica ...
... did not receive any diagnosis. Since 2 years, the leg pain increased and became resistant to analgesics and intolerant to his clothes. His motor and sensory examination was found to be normal. His Straight Leg Raise (SLR) was negative. There was “point hyperesthesia” in a localized area. His physica ...
Morphology and Differential Diagnosis
... brown pigmentation, most frequently seen on the anterior legs • “Dimple” sign • May be a reactive process to an insect bite reaction rather than a tumor • If multiple, sometimes associated with systemic lupus erythematosis ...
... brown pigmentation, most frequently seen on the anterior legs • “Dimple” sign • May be a reactive process to an insect bite reaction rather than a tumor • If multiple, sometimes associated with systemic lupus erythematosis ...
article in PDF - Our Dermatology Online journal
... The clinical and radiological suspicious in this case was of a primitive breast carcinoma; the difficulty in the diagnosis of this tumor was to differentiate if the neoplasia was a skin primary or a breast one, in particular a clear cell hidradenoma, a very rare breast tumor that share the histologi ...
... The clinical and radiological suspicious in this case was of a primitive breast carcinoma; the difficulty in the diagnosis of this tumor was to differentiate if the neoplasia was a skin primary or a breast one, in particular a clear cell hidradenoma, a very rare breast tumor that share the histologi ...
Epithelioid sarcoma
Epithelioid sarcoma is a rare soft tissue sarcoma arising from mesenchymal tissue and characterized by epithelioid-like features. It accounts for less than 1% of all soft tissue sarcomas. It was first clearly characterized by F.M. Enzinger in 1970. It commonly presents itself in the distal limbs (fingers, hands, forearms, or feet) of young adults as a small, soft mass or a series of bumps. A proximal version has also been described, frequently occurring in the upper extremities. Rare cases have been reported in the pelvis, vulva, penis, and spine.Histologically, epithelioid sarcoma forms nodules with central necrosis surrounded by bland, polygonal cells with eosinophilic cytoplasm and peripheral spindling. Epithelioid sarcomas typically express vimentin, cytokeratins, epithelial membrane antigen, and CD34, whereas they are usually negative for S100, desmin, and FLI-1. They typically stain positive for CA125.Epithelioid sarcoma most commonly strikes young adults, yet no age group is immune. The disease has a tendency to develop local recurrences and metastasis thereafter to regional lymph nodes, lung, bone, brain, and other locations, including the scalp. Generally speaking, epithelioid sarcoma has a high rate of relapse after initial treatment and tends to recur locally (at or near the original tumor site). Epithelioid sarcoma also demonstrates lymphatic spread (in 22-48% of cases), and metastasis (in 21-63% of cases). These events, as well as advanced stage (progression) and grade (aggressiveness), are predictive of an overall worse outcome. The overall five-year survival rate for epithelioid sarcoma is anywhere from 25 to 78%. Importantly, the 10-year and 15-year survival rate drops off significantly. Associated with a more positive outcome are younger age, female vs. male sex, distal vs. proximal location, smaller tumor size, and negative margins upon tumor resection.