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Epub ahead of print  - Journal of Clinical and Translational
Epub ahead of print - Journal of Clinical and Translational

... cell signaling, differentiation and tissue homeostasis (Choi et al. 2017). Additionally, it is through membrane receptors known as integrins and mechanosensitive ion channels in the ECM by which cells perceive signals such as shear stress and tensile forces (Fernandes et al. 2009). Decellularized he ...
The little brain on the heart
The little brain on the heart

... chronotropism, dromotropism, and regional inotropism ultimately depends on the integration of multiple cardiovascular sensory and central neuronal inputs within the intrathoracic neuroaxis. Intrathoracic local circuit neurons play a key role in such integration. Local circuit neurons Interposed betw ...
NATA Official Statement on Commotio Cordis
NATA Official Statement on Commotio Cordis

... NATA Official Statement on Commotio Cordis According to the U.S. Commotio Cordis Registry, since 1995, 188 athletes have died from blunt force injury to the heart (commotio cordis). Of those 188 fatalities, the mean age was 14.7 years and 96% were male athletes according to the Heart Center at TUFTS ...
Influence of Myocardial Fibrosis on Left Ventricular Diastolic Function
Influence of Myocardial Fibrosis on Left Ventricular Diastolic Function

... in subjects without structural heart disease. In contrast, LGE positivity was common in patients with cardiomyopathy, being present in 89% of patients with ischemic cardiomyopathy, in 59% of those with dilated cardiomyopathy, and in 67% of those with hypertrophic cardiomyopathy. The median LGE score ...
AA CRT ICD S-ICD Booklet.indd
AA CRT ICD S-ICD Booklet.indd

... Later on, once the procedure is over, the main thing that you need to be aware of is that the device can give you a shock. Most people will feel this, unless they have fainted due to a fast heart rhythm, and many people find it unpleasant (though how much is quite variable). It can feel like suddenl ...
Role of PET/ CT for the Identification of Cardiac Sarcoid Disease
Role of PET/ CT for the Identification of Cardiac Sarcoid Disease

... dle-aged adults(11,12) . Such middle-aged patients ...
Automated detection of effective left-ventricular
Automated detection of effective left-ventricular

... minus Min must be between 0.125 and 8. Any beat that does not meet these effective pacing criteria receives an ineffective classification. ...
Print - Circulation Research
Print - Circulation Research

... diluted with twice its volume of isotonie sodium chloride solution, or with fresh egg white diluted similarly. Sensitization was produced bj* 5 ml. of diluted antigen intraperitoneally and 5 ml. intramuscularly, 50 to 60 days before the experiment. ...
Left Ventricular Non-Compaction: Mid-myocardial
Left Ventricular Non-Compaction: Mid-myocardial

... infarction. In our study, four of the 15 patients underwent invasive coronary angiography, according to the clinical judgment at the time of diagnosis. Only one patient had coronary artery lesions causing a greater than 50% narrowing with no history of myocardial infarction. As mentioned above LGE w ...
Obstetric Anesthesia— What the obstetrician should know.
Obstetric Anesthesia— What the obstetrician should know.

... • Is Cardiotronic system useful and easy for routine outpatient use? • Can we detect an early increase in SVR in preeclamptic pregnancies? • How do hemodynamics of spinal anesthesia and CS compare in pre-eclamptics vs. normals? ...
Remodelling of gap junctions and connexin expression in diseased
Remodelling of gap junctions and connexin expression in diseased

... the AV node to the ends of the Purkinje fibres.11 Though these features of connexin expression are common to most mammalian species, there are notable exceptions. For example, Cx40 is not detectable in rat atrium or the guinea pig conduction system.6,17 Species variations in co-expression patterns wi ...
Acute Responses to Intermittent and Continuous Exercise in Heart
Acute Responses to Intermittent and Continuous Exercise in Heart

... MICE, indicating similar cardiopulmonary stimulus between the 2 exercise modes. However, during HIIE, patients exercised for a shorter cycling exercise time, at a higher power output, and with higher external work efficiency. This illustrates the superior efficiency of optimized HIIE compared with M ...
Chapter 40
Chapter 40

... Practice Question #2 A nurse is administering digoxin, 0.125 mg, to a patient. Which nursing interventions will the nurse implement? (Select all that apply.) A. Checking the apical pulse rate before administration B. Monitoring the patient’s serum digoxin level C. Instructing patient to report puls ...
Full Text [Download PDF]
Full Text [Download PDF]

... veins.9 Lateral, posterolateral and anterolateral veins are usually preferred as target veins for placement of the left ventricle electrode.6 AIV might be useful for some therapeutic approaches.9 Therefore, it is crucial that the anatomic variations of the cardiac venous circulation are accurately d ...
Recovery-Phase Patterns of STSegment
Recovery-Phase Patterns of STSegment

... before beginning an exercise program.23 There were 81 men and 19 women whose mean age was 47±+13 (SD) years. Each had normal findings on cardiac examination and resting electrocardiogram before exercise; no subject was included in this group if exercise systolic blood pressure exceeded 210 mm Hg or ...
Lymphatics of the Heart
Lymphatics of the Heart

... neath the epicardium or endocardium form inconsistent patterns unlike lymphatics or blood vessels and are recognized easily. Hearts of 25 pigs, 13 dogs, and 20 humans were examined. Observation of subepicardial and subendocardial lymphatics was facilitated by cutting open the hearts according to a m ...
Circulation Research SEPTEMBER
Circulation Research SEPTEMBER

... systolic and diastolic pressures were recorded from a needle cannula in the ventricular apex before and during constriction of the aorta. The maximum rate of rise of left ventricular systolic pressure (dP/dt max) was obtained with an R-C circuit. Body temperature was kept constant with a heating pad ...
Sinus of Valsalva Aneurysm with Rupturing into the Right Atrium ¾ A
Sinus of Valsalva Aneurysm with Rupturing into the Right Atrium ¾ A

... until it eventually ruptures between the 3rd and 4th decades of life. The commonest sites of aneurysm ruptures are cardiac chambers, interventricular septum,8 or pericardial space.9 Dilated sinus of Valsalva aneurysm also can lead to distortion of aortic valve and aortic regurgitation. Un-ruptured s ...
Cardiac Output Venous Return
Cardiac Output Venous Return



... (table 1). Twenty two patients had ischaemic heart disease and eight had idiopathic dilated cardiomyopathy. Antifailure medication consisted of diuretics (all patients), digoxin (14), angiotensin-converting enzyme inhibitors (24), and other vasodilators (13). Findings were compared with those of age ...
Ratio of Peak Early to Late Diastolic Filling Velocity of the Left
Ratio of Peak Early to Late Diastolic Filling Velocity of the Left

... and Stroke has characterized cardioembolic stroke as an important clinical entity, since it is the most common cause of death in patients with acute ischemic stroke.1−3)Transesophageal echocardiography(TEE)has been established as an essential investigation for detecting thromboembolic sources and de ...
Paper
Paper

... Model abstraction [9] was originally proposed as a powerful state-reduction technique to alleviate the state explosion problem [10] during model-checking. Models are created as abstraction of the original system. Since the abstracted models have more behaviors than the original system, properties sa ...
Essential Opposite Roles of ERK and Akt Signaling in Cardiac
Essential Opposite Roles of ERK and Akt Signaling in Cardiac

... advocating the use of this drug, despite its small therapeutic index (Gheorghiade et al., 2013; van Veldhuisen et al., 2013). A comprehensive understanding of the mechanisms involved in CS-induced effects on heart contractility may lead to new pharmacological tools for the improvement of CS use. The ...
COMPLICATIONS OF AF ABLATION AFA Booklet
COMPLICATIONS OF AF ABLATION AFA Booklet

... ablation for Atrial Fibrillation are discussed. Before listing and describing individual complications it is necessary to explore some important definitions. The safety of catheter ablation refers to the risks, or complications, involved in the procedure. When deciding whether or not to undergo the a ...
Papillary Muscle Shortening in the Intact Dog
Papillary Muscle Shortening in the Intact Dog

... match was obtained by repeating the maneuver. Moreover, longer cycles on the recorded ECG (due to sinus arrhythmia) corresponded to an appropriately increased number of frames between the matching flash-marked frames. The cineradiographic filming rate was 30 frames/sec. In three dogs an additional f ...
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Electrocardiography



Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.
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