Reendothelialization of Human Heart Valve Neoscaffolds Using
... Background: Heart valve tissue engineering represents a concept for improving the current methods of valvular heart disease therapy. The aim of this study was to develop tissue engineered heart valves combining human umbilical vein endothelial cells (HUVECs) and decellularized human heart valve mat ...
... Background: Heart valve tissue engineering represents a concept for improving the current methods of valvular heart disease therapy. The aim of this study was to develop tissue engineered heart valves combining human umbilical vein endothelial cells (HUVECs) and decellularized human heart valve mat ...
Assessment of Pulmonary Arterial Hypertension by Magnetic
... The RV diastolic function could be evaluated by analyzing the blood flow pattern through the tricuspid valve. As shown in Figure 8, 2 sets of velocity-encoded magnitude and phase images are acquired at the tricuspid valve level. The images are used to derive the flow curve, from which the early and ...
... The RV diastolic function could be evaluated by analyzing the blood flow pattern through the tricuspid valve. As shown in Figure 8, 2 sets of velocity-encoded magnitude and phase images are acquired at the tricuspid valve level. The images are used to derive the flow curve, from which the early and ...
Pathophysiology and treatment of alveolar–capillary dysfunction in
... pathophysiologic role, the opportunity to consider the alveolar–capillary membrane a therapeutic target is probably underestimated. The importance of considering an altered gas exchange as a target of treatment is emphasized by the demonstration that, despite major airway abnormalities observed in H ...
... pathophysiologic role, the opportunity to consider the alveolar–capillary membrane a therapeutic target is probably underestimated. The importance of considering an altered gas exchange as a target of treatment is emphasized by the demonstration that, despite major airway abnormalities observed in H ...
Steven Shea, Li Pan, David A. Bluemke and João A.C. Lima Thor
... information on segmental myocardial function.16 Strain rate was determined as the first derivative of strain measurements (Ecc) at 2 consecutive time points.17 Peak systolic strain rate was derived from the strain trace as shown in Figure 1. By definition, systolic strain and strain rate are negativ ...
... information on segmental myocardial function.16 Strain rate was determined as the first derivative of strain measurements (Ecc) at 2 consecutive time points.17 Peak systolic strain rate was derived from the strain trace as shown in Figure 1. By definition, systolic strain and strain rate are negativ ...
Gallop Rhythm of the Heart
... The first andl second heart sounds are indicated by 1 and respectively. Each gallop sound (vG and aG) occurs simultaneously with a gallop bulge (G). In the second cycle in B a definite ventricular gallop sound was not recorded though the gallop was still iresent, as evidenced by a prominent precordi ...
... The first andl second heart sounds are indicated by 1 and respectively. Each gallop sound (vG and aG) occurs simultaneously with a gallop bulge (G). In the second cycle in B a definite ventricular gallop sound was not recorded though the gallop was still iresent, as evidenced by a prominent precordi ...
World Heart Corporation (WHRT)
... Levacor, which the company obtained as part of its July 2005 acquisition of MedQuest Products, Inc. WorldHeart began a pivotal US trial of this device in Bridge-to-Transplant in January 2010. The Levacor uses a magnetically-levitated rotor resulting in no moving parts that are subject to wear, and i ...
... Levacor, which the company obtained as part of its July 2005 acquisition of MedQuest Products, Inc. WorldHeart began a pivotal US trial of this device in Bridge-to-Transplant in January 2010. The Levacor uses a magnetically-levitated rotor resulting in no moving parts that are subject to wear, and i ...
Comparison of Uhl`s anomaly, right ventricular outflow tract
... in untranslated 5’ and 3’ regions of TGF-β3 gene have been identified in the causation of ARVD/C-1. TGF-β3 induces a fibrotic response in various tissues in vivo44 and modulate expression of genes encoding desmosomal proteins in different cell types. Experiments have shown that incubation of cardiac ...
... in untranslated 5’ and 3’ regions of TGF-β3 gene have been identified in the causation of ARVD/C-1. TGF-β3 induces a fibrotic response in various tissues in vivo44 and modulate expression of genes encoding desmosomal proteins in different cell types. Experiments have shown that incubation of cardiac ...
Coronary Artery Atherosclerosis Is Related to Reduced Regional
... information on segmental myocardial function.16 Strain rate was determined as the first derivative of strain measurements (Ecc) at 2 consecutive time points.17 Peak systolic strain rate was derived from the strain trace as shown in Figure 1. By definition, systolic strain and strain rate are negativ ...
... information on segmental myocardial function.16 Strain rate was determined as the first derivative of strain measurements (Ecc) at 2 consecutive time points.17 Peak systolic strain rate was derived from the strain trace as shown in Figure 1. By definition, systolic strain and strain rate are negativ ...
Velocity of Left Ventricular Contraction in Man
... period of several heart beats. This method of injection was chosen because with it there is increased statistical probability of thorough left ventricular mixing before "washout" utilized in calculations. 5-10 such curves, free of ectopic beats, were obtained in each condition of the study. Special ...
... period of several heart beats. This method of injection was chosen because with it there is increased statistical probability of thorough left ventricular mixing before "washout" utilized in calculations. 5-10 such curves, free of ectopic beats, were obtained in each condition of the study. Special ...
Cardiac arrhythmias in coronary heart disease.
... and the arrhythmias associated with acute coronary syndromes, chronic coronary heart disease and cardiac surgery. It excludes arrhythmias not associated with coronary heart disease such as supraventricular tachycardias associated with accessory pathways or dual atrioventricular (AV) nodal physiology ...
... and the arrhythmias associated with acute coronary syndromes, chronic coronary heart disease and cardiac surgery. It excludes arrhythmias not associated with coronary heart disease such as supraventricular tachycardias associated with accessory pathways or dual atrioventricular (AV) nodal physiology ...
Fishing for the genetic basis of cardiovascular disease
... Cardiovascular disease (CVD) has recently overtaken infectious disease to become the biggest global killer. Genetic factors have emerged as being of major importance in the pathogenesis of CVD. Owing to disease heterogeneity, variable penetrance and high mortality, human genetic studies alone are no ...
... Cardiovascular disease (CVD) has recently overtaken infectious disease to become the biggest global killer. Genetic factors have emerged as being of major importance in the pathogenesis of CVD. Owing to disease heterogeneity, variable penetrance and high mortality, human genetic studies alone are no ...
Role of autonomic reflexes in syncope associated with
... Nonhemodynamic mechanisms may be even more readly suspected when heart rate is not particularly high . It is well known that the onset of paroxysmal tachycardia produces a hemodynamic disturbance that evokes a compensatory cardiovascular response (2,3) . This response, which is mediated mainly by re ...
... Nonhemodynamic mechanisms may be even more readly suspected when heart rate is not particularly high . It is well known that the onset of paroxysmal tachycardia produces a hemodynamic disturbance that evokes a compensatory cardiovascular response (2,3) . This response, which is mediated mainly by re ...
JE Muller, PL Ludmer, SN Willich, GH Tofler, G Aylmer, I
... and it often occurs without warning in an out-of-hospital setting. Retrieval of physiologic data from those who die is impossible, while in those who are resuscitated, the period of arrest and the techniques of resuscitation obscure the events that preceded the arrest. Of ...
... and it often occurs without warning in an out-of-hospital setting. Retrieval of physiologic data from those who die is impossible, while in those who are resuscitated, the period of arrest and the techniques of resuscitation obscure the events that preceded the arrest. Of ...
Partial abnormal drainage of superior and inferior caval
... connection of the IVC to the left atrium is also described. In heterotaxy syndrome, the persistence of the left superior vena cava is found in 30–50% of the cases. The persistent LSVC rarely drains directly to the left atrium, situation that is followed by the necessity to separate the two venous re ...
... connection of the IVC to the left atrium is also described. In heterotaxy syndrome, the persistence of the left superior vena cava is found in 30–50% of the cases. The persistent LSVC rarely drains directly to the left atrium, situation that is followed by the necessity to separate the two venous re ...
VSD
... in infants with pmVSD (near to the conduction system) – introduction systems and current devices are too stiff and harmfull Self-expandable devices give most therapeutic options to close larger defects or defects near to the aortic valve the use of self expandable devices in pmVSD bears the risk for ...
... in infants with pmVSD (near to the conduction system) – introduction systems and current devices are too stiff and harmfull Self-expandable devices give most therapeutic options to close larger defects or defects near to the aortic valve the use of self expandable devices in pmVSD bears the risk for ...
Coronary Sinus-Still a Potential Site for Research
... draining the ischemic area. In contrast to SRP, the regional cardiac veins are emptied by suction of blood before retroinfusion. Early clinical evaluations have shown benefits of pressure-controlled intermittent coronary sinus occlusion (PICSO) during coronary artery bypass grafting [9] and experime ...
... draining the ischemic area. In contrast to SRP, the regional cardiac veins are emptied by suction of blood before retroinfusion. Early clinical evaluations have shown benefits of pressure-controlled intermittent coronary sinus occlusion (PICSO) during coronary artery bypass grafting [9] and experime ...
a study on the echocardiography of the mitral valve in normal
... still able to form a tight seal. When regurgitation does occur, it can cause complications and troublesome symptoms such as shortness of breath, chest pain. Arrhythmias are problems with the rate or rhythm of the heartbeat. regurgitation can get worse over time and lead to changes in the heart’s siz ...
... still able to form a tight seal. When regurgitation does occur, it can cause complications and troublesome symptoms such as shortness of breath, chest pain. Arrhythmias are problems with the rate or rhythm of the heartbeat. regurgitation can get worse over time and lead to changes in the heart’s siz ...
Left Ventricular Systolic Dysfunction in Asymptomatic Black
... Teaching Hospital, Gwagwalada, Abuja, Nigeria, with a diagnosis of hypertension from April 2006 to August 2013. Two thousand one subjects were initially recruited for the study, while 1,947 were finally enrolled. These patients were new referrals with hypertension from both family and general physic ...
... Teaching Hospital, Gwagwalada, Abuja, Nigeria, with a diagnosis of hypertension from April 2006 to August 2013. Two thousand one subjects were initially recruited for the study, while 1,947 were finally enrolled. These patients were new referrals with hypertension from both family and general physic ...
left ventricular endocardial longitudinal and transverse changes during
... calculate stroke volume. All distances, flows, and pressures were displayed and recorded simultaneously on the same screen by the Sonometrics system to ensure that all data were synchronized and recorded on the same time line. An effort was made to record the measurements under stable hemodynamic co ...
... calculate stroke volume. All distances, flows, and pressures were displayed and recorded simultaneously on the same screen by the Sonometrics system to ensure that all data were synchronized and recorded on the same time line. An effort was made to record the measurements under stable hemodynamic co ...
Device-Based Therapy of Cardiac Rhythm Abnormalities
... The focus of these guidelines is the appropriate use of heart rhythm devices (pacemakers for bradyarrhythmias and heart failure management, e.g., cardiac resynchronization, and implantable cardioverter-defibrillators [ICDs]), not the treatment of cardiac arrhythmias. The fact that the use of a devic ...
... The focus of these guidelines is the appropriate use of heart rhythm devices (pacemakers for bradyarrhythmias and heart failure management, e.g., cardiac resynchronization, and implantable cardioverter-defibrillators [ICDs]), not the treatment of cardiac arrhythmias. The fact that the use of a devic ...
Cardiac arrhythmias in acute coronary syndromes
... The article has been co-published with permission in EP-Europace, European Heart Journal - Acute Cardiovascular Care and EuroIntervention. All rights reserved in respect of European Heart Journal - Acute Cardiovascular Care and EuroIntervention. © The Authors 2014. For EP-Europace, © The Author 2014 ...
... The article has been co-published with permission in EP-Europace, European Heart Journal - Acute Cardiovascular Care and EuroIntervention. All rights reserved in respect of European Heart Journal - Acute Cardiovascular Care and EuroIntervention. © The Authors 2014. For EP-Europace, © The Author 2014 ...
European Journal of Heart Failure
... Each component was analysed separately and the disease course after the first event was studied. The multistate analysis showed that the randomised allocation to ASV significantly increased the risk of cardiovascular death without prior hospitalisation for worsening heart failure or life-saving even ...
... Each component was analysed separately and the disease course after the first event was studied. The multistate analysis showed that the randomised allocation to ASV significantly increased the risk of cardiovascular death without prior hospitalisation for worsening heart failure or life-saving even ...
Cardiogenic Shock Due to Dynamic Left Ventricular Outflow Tract
... The fact that cases have been reported of patients with lesion-free coronary arteries4,13 has lead some authors to propose dynamic LVOT obstruction as the trigger of myocardial damage, although the existence of a thrombus that lyses before coronariography, or vasospasm, cannot be excluded. Compensat ...
... The fact that cases have been reported of patients with lesion-free coronary arteries4,13 has lead some authors to propose dynamic LVOT obstruction as the trigger of myocardial damage, although the existence of a thrombus that lyses before coronariography, or vasospasm, cannot be excluded. Compensat ...
Growth differentiation factor-15 (GDF
... 5’-TTGATTTTGGAGGGATCTCG-3’; CTGF: 5’-TACCAATGACAACGCCTCCT-3’ and 5’-CCGTCGGTACATACTCCACA-3’; Collagen I: 5’-CCCCAGCCACAAAGAGTCTA-3’ and 5’-TACCTGAGGCCGTTCTGTAC-3’; Collagen III: 5’-GAAGGGCAGGGAACAACTTG-3’ and 5’-TTTGGCATGGTTCTGGCTTC-3’. Statistical analysis The data are expressed as the means ± stan ...
... 5’-TTGATTTTGGAGGGATCTCG-3’; CTGF: 5’-TACCAATGACAACGCCTCCT-3’ and 5’-CCGTCGGTACATACTCCACA-3’; Collagen I: 5’-CCCCAGCCACAAAGAGTCTA-3’ and 5’-TACCTGAGGCCGTTCTGTAC-3’; Collagen III: 5’-GAAGGGCAGGGAACAACTTG-3’ and 5’-TTTGGCATGGTTCTGGCTTC-3’. Statistical analysis The data are expressed as the means ± stan ...
Electrocardiography
Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.