Trypanosome Outline
... chronic infection, which does not mean benign. A person can be infected for months or even years without obvious symptoms of the disease emerging. When symptoms do emerge, the disease is already at an advanced stage. Trypanosoma brucei rhodesiense (T.b. rhodesiense) is found in southern and east Afr ...
... chronic infection, which does not mean benign. A person can be infected for months or even years without obvious symptoms of the disease emerging. When symptoms do emerge, the disease is already at an advanced stage. Trypanosoma brucei rhodesiense (T.b. rhodesiense) is found in southern and east Afr ...
Kinetoplastida: new therapeutic strategies
... shown that it has some efficacy in early chronic infections (Sosa-Estani et al., 1998), and a long term clinical trial (BENEFIT) is now underway to determine the extent of use of this drug for this indication (http://clinicaltrials.gov/show/NCT00123916). There are several rational approaches to the ...
... shown that it has some efficacy in early chronic infections (Sosa-Estani et al., 1998), and a long term clinical trial (BENEFIT) is now underway to determine the extent of use of this drug for this indication (http://clinicaltrials.gov/show/NCT00123916). There are several rational approaches to the ...
Treatment of late stage sleeping sickness caused by T.b. gambiense
... extensively discussed during the last decade. Generally an immune reaction is thought to underlie the syndrome [2, 21, 23], but the mechanism remains unknown. In a large-scale study [25] the concomitant application of prednisolone was shown to have a protective effect against encephalopathies. There ...
... extensively discussed during the last decade. Generally an immune reaction is thought to underlie the syndrome [2, 21, 23], but the mechanism remains unknown. In a large-scale study [25] the concomitant application of prednisolone was shown to have a protective effect against encephalopathies. There ...
DESCRIPTION Naftifine Hydrochloride Cream, 1% contains the
... clinical significance is unknown. Naftifine hydrochloride has been shown to exhibit fungicidal activity in vitro against a broad spectrum of organisms, including Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Epidermophyton floccosum, Microsporum canis, Microsporum audouin ...
... clinical significance is unknown. Naftifine hydrochloride has been shown to exhibit fungicidal activity in vitro against a broad spectrum of organisms, including Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Epidermophyton floccosum, Microsporum canis, Microsporum audouin ...
Eflornithine
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Eflornithine (α-difluoromethylornithine or DFMO) is a drug found to be effective in the treatment of facial hirsutism (excessive hair growth) as well as in African trypanosomiasis (sleeping sickness). Eflornithine hydrochloride cream for topical application is meant for women affected by facial hirsutism. Eflornithine for injection against sleeping sickness is manufactured by Sanofi Aventis and sold under the brand name Ornidyl in the USA. Both are prescription drugs.It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
