FYVE-Dependent Endosomal Targeting of an Arrestin
... In this report, we chose to focus on the protein AdcA from D. discoideum (Figure 1A–B). Arrestin-domain containing proteins extended with a FYVE domain were also found in D. purpureum, Polysphondylium pallidum, Entamoeba histolytica and E. dispar, other members of the Conosea group within the Amoebo ...
... In this report, we chose to focus on the protein AdcA from D. discoideum (Figure 1A–B). Arrestin-domain containing proteins extended with a FYVE domain were also found in D. purpureum, Polysphondylium pallidum, Entamoeba histolytica and E. dispar, other members of the Conosea group within the Amoebo ...
Pro-cognitive properties of T cells.Nat Rev Immunol
... considerable distances via high-affinity neurotransmitter receptors54,55. Immune cells express a wide range of receptors for adrenaline, noradrenaline and dopamine. Stress, ...
... considerable distances via high-affinity neurotransmitter receptors54,55. Immune cells express a wide range of receptors for adrenaline, noradrenaline and dopamine. Stress, ...
June 1, 2008 Principles of Security: Human, Cyber and Biological
... to meet the next challenge that arises. Solving the current challenge will not eliminate the general vulnerability. Instead, it is necessary to create systems that are able to address challenges of various kinds that surely will arise in the future. The changes in global communication and transport ...
... to meet the next challenge that arises. Solving the current challenge will not eliminate the general vulnerability. Instead, it is necessary to create systems that are able to address challenges of various kinds that surely will arise in the future. The changes in global communication and transport ...
Transplantation Immunology
... that serve as the targets of rejection the antibodies and T cells that react against these antigens are said to be alloreactive ...
... that serve as the targets of rejection the antibodies and T cells that react against these antigens are said to be alloreactive ...
Nicotine Strongly Activates Dendritic Cell–Mediated Adaptive
... anatomic localization, cell-surface phenotype, and function. Human DCs are traditionally divided into two main populations: MYELOID DCs and PLASMACYTOID DCs. DCs were initially thought to be immunogenic, actively inducing or upregulating immune responses. However, recent advances demonstrated th ...
... anatomic localization, cell-surface phenotype, and function. Human DCs are traditionally divided into two main populations: MYELOID DCs and PLASMACYTOID DCs. DCs were initially thought to be immunogenic, actively inducing or upregulating immune responses. However, recent advances demonstrated th ...
INTRODUCTION - HAL
... increased during relapses and downregulated during remissions are partly or predominantly regulated by the NF-B proteins. The NF-B transcription factors play a central role in the triggering and coordination of both innate and adaptive immune responses by regulating the expression of a wide varie ...
... increased during relapses and downregulated during remissions are partly or predominantly regulated by the NF-B proteins. The NF-B transcription factors play a central role in the triggering and coordination of both innate and adaptive immune responses by regulating the expression of a wide varie ...
CURRICULUM VITAE - GITAM Institute of Science
... Pharmacological screening of various medicinal plants for antiepileptic potential in different animal models (Mouse & Drosophila Mutants) ...
... Pharmacological screening of various medicinal plants for antiepileptic potential in different animal models (Mouse & Drosophila Mutants) ...
mukesh-kumar-all-india-institute-of-medical
... » PAP is an isozyme of alkaline phosphatase » 513 amino acid peripheral membrane glycoprotein anchored ...
... » PAP is an isozyme of alkaline phosphatase » 513 amino acid peripheral membrane glycoprotein anchored ...
PLATELET
... (A) Circulating platelets (a) interact with activated endothe Cells (b) or subendothelial matrix (c) to form mural thromb providing a substrate for adhesion of leukocytes (e) which also adhere to activated endothelium (f) prior to extravasation through the vessel wall (g). (B) Vascular cell adhesio ...
... (A) Circulating platelets (a) interact with activated endothe Cells (b) or subendothelial matrix (c) to form mural thromb providing a substrate for adhesion of leukocytes (e) which also adhere to activated endothelium (f) prior to extravasation through the vessel wall (g). (B) Vascular cell adhesio ...
B Cell–Specific MHC Class II Deletion Reveals Multiple
... ystemic lupus erythematosus (SLE) is a chronic autoimmune disease with multiple immunologic and clinical manifestations. A hallmark of SLE is the presence of autoantibodies to ubiquitous self-Ags. Ab deposition in kidneys of lupus patients underpins the long-held notion that autoantibodies play a ma ...
... ystemic lupus erythematosus (SLE) is a chronic autoimmune disease with multiple immunologic and clinical manifestations. A hallmark of SLE is the presence of autoantibodies to ubiquitous self-Ags. Ab deposition in kidneys of lupus patients underpins the long-held notion that autoantibodies play a ma ...
Lymphatic System - Dr. Annette M. Parrott
... Spleen • White pulp – B and T cells carry out immune function. ...
... Spleen • White pulp – B and T cells carry out immune function. ...
Systems biology in vaccine design
... or its derived antigenic proteins or its toxins + adjuvant. The antigens stimulate the body’s immune system to recognize the agent as foreign, induces specific immune responses (immunogenicity). Vaccines can be prophylactic (e.g. to prevent or reduce the effects of a future infection by any natural ...
... or its derived antigenic proteins or its toxins + adjuvant. The antigens stimulate the body’s immune system to recognize the agent as foreign, induces specific immune responses (immunogenicity). Vaccines can be prophylactic (e.g. to prevent or reduce the effects of a future infection by any natural ...
STRUCTURAL STUDIES OF IMMUNOGLOBULINS
... evidence in favour of any of the many theories advanced is lacking. I only wish to make a brief comment here about the sequence work on the variable region of rabbit IgG heavy chains which developed as part of the other structural work discussed above. There are perhaps two main points under immedia ...
... evidence in favour of any of the many theories advanced is lacking. I only wish to make a brief comment here about the sequence work on the variable region of rabbit IgG heavy chains which developed as part of the other structural work discussed above. There are perhaps two main points under immedia ...
INTERNATIONAL MEDICAL REVIEW ON DOWN`S SYNDROME
... different therapeutic guidelines available. This could lead to the inclusion of a greater number of patients within the umbrella of this diagnosis. However, what appears to be the most highly supported theory is the influence of the changes in T helper lymphocyte activity (Th), which are activated a ...
... different therapeutic guidelines available. This could lead to the inclusion of a greater number of patients within the umbrella of this diagnosis. However, what appears to be the most highly supported theory is the influence of the changes in T helper lymphocyte activity (Th), which are activated a ...
Cytokines in anaesthesia - Oxford Academic
... The antigen receptors of B lymphocytes (bursa or bone-marrow derived lymphocytes) are membranebound forms of antibodies. Antigen binds to these membrane-bound antibody molecules to initiate the sequence of B cell activation, which culminates in the production of effector cells that actively secrete ...
... The antigen receptors of B lymphocytes (bursa or bone-marrow derived lymphocytes) are membranebound forms of antibodies. Antigen binds to these membrane-bound antibody molecules to initiate the sequence of B cell activation, which culminates in the production of effector cells that actively secrete ...
download--no narration
... by clicking on the “View” menu and selecting “Slide Sorter.” • To print out the presentation, click on the “File” menu, “Print.” Then under “Print What”, select “Handouts” and Print 3, 4 or 6 slides per page to save paper and printer ink. Otherwise each slide will print on its own page • Remember th ...
... by clicking on the “View” menu and selecting “Slide Sorter.” • To print out the presentation, click on the “File” menu, “Print.” Then under “Print What”, select “Handouts” and Print 3, 4 or 6 slides per page to save paper and printer ink. Otherwise each slide will print on its own page • Remember th ...
Questions for exam #1
... says otherwise. Therefore each part, A, B, C, etc. is usually worth 6 points. Explanations that simply repeated the circled answer did not receive credit. Additional information had to be provided. 1. Claudins are a family of proteins found only in tight junctions. Claudin 16 has 4 hydrophobic TM se ...
... says otherwise. Therefore each part, A, B, C, etc. is usually worth 6 points. Explanations that simply repeated the circled answer did not receive credit. Additional information had to be provided. 1. Claudins are a family of proteins found only in tight junctions. Claudin 16 has 4 hydrophobic TM se ...
Loose connective tissue
... N.B. ! The hematocrit is measured by centrifuging a blood sample to which anticoagulants have been added, and then calculating the percentage of the centrifuge tube volume occupied by the erythrocytes compared with that of the whole blood. A normal hematocrit reading is about 39% to 50% in men and ...
... N.B. ! The hematocrit is measured by centrifuging a blood sample to which anticoagulants have been added, and then calculating the percentage of the centrifuge tube volume occupied by the erythrocytes compared with that of the whole blood. A normal hematocrit reading is about 39% to 50% in men and ...
Free fucose is a danger signal to human intestinal epithelial cells
... Fucose is present in foods, and it is a major component of human mucin glycoproteins and glycolipids. L -Fucose can also be found at the terminal position of many cell-surface oligosaccharide ligands that mediate cell-recognition and adhesion-signalling pathways. Mucin fucose can be released through ...
... Fucose is present in foods, and it is a major component of human mucin glycoproteins and glycolipids. L -Fucose can also be found at the terminal position of many cell-surface oligosaccharide ligands that mediate cell-recognition and adhesion-signalling pathways. Mucin fucose can be released through ...
Haemoglobin (Roll no. 22
... • Decrease of hemoglobin, with or without an absolute decrease of red blood cells, leads to symptoms of anemia. As absence of iron decreases heme synthesis, red blood cells in iron deficiency anemia are hypochromic (lacking the red hemoglobin pigment) and microcytic (smaller than normal). • Sickle ...
... • Decrease of hemoglobin, with or without an absolute decrease of red blood cells, leads to symptoms of anemia. As absence of iron decreases heme synthesis, red blood cells in iron deficiency anemia are hypochromic (lacking the red hemoglobin pigment) and microcytic (smaller than normal). • Sickle ...
Immunotoxicity derived from manipulating leukocytes with lipid
... tissue. This interaction may lead to signal cascades upon activation of pattern recognition receptors (PRRs) [15–17]. PRRs are proteins expressed by cells of the innate immune arm to identify pathogen-associated molecular patterns (PAMPs), which are associated with microbial pathogens or cellular st ...
... tissue. This interaction may lead to signal cascades upon activation of pattern recognition receptors (PRRs) [15–17]. PRRs are proteins expressed by cells of the innate immune arm to identify pathogen-associated molecular patterns (PAMPs), which are associated with microbial pathogens or cellular st ...
... his thesis has focused on two unique lymphocyte subsets that play an important role in anti-tumor immune responses and interactions between these subsets. iNKT cells constitute a lymphocyte lineage sharing characteristics of both T cells and NK cells. They display a highly restricted TCR repertoire ...
Polyclonal B cell response
Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.