Double-Stranded RNA Induces an Antiviral Defense Status in
... Emerging evidence suggests an important role for human epidermal keratinocytes in innate immune mechanisms against bacterial and viral skin infections. The proinflammatory effect of viral infections can be mimicked by double-stranded RNA (dsRNA). Herein, we demonstrate that keratinocytes express all ...
... Emerging evidence suggests an important role for human epidermal keratinocytes in innate immune mechanisms against bacterial and viral skin infections. The proinflammatory effect of viral infections can be mimicked by double-stranded RNA (dsRNA). Herein, we demonstrate that keratinocytes express all ...
Reproductive Immunology: Biomarkers of
... Infertility is classified as primary or secondary. Primary infertility designates those couples who never have conceived, and secondary infertility designates couples who have conceived but have failed to deliver during one or more years of unprotected intercourse (33). Primary infertiles have a low ...
... Infertility is classified as primary or secondary. Primary infertility designates those couples who never have conceived, and secondary infertility designates couples who have conceived but have failed to deliver during one or more years of unprotected intercourse (33). Primary infertiles have a low ...
Lectins, Mitogens and Agglutinins
... Most lectins given orally are immunogenic. Pooled human blood typically contains high titre anti-banana lectin (BanLec-1) IgG4. Lectins can modulate IgE responses to other antigens [hG3 also does this, and there is some evidence that CD23 (the low-affinity IgE receptor) is in itself a C-type lectin. ...
... Most lectins given orally are immunogenic. Pooled human blood typically contains high titre anti-banana lectin (BanLec-1) IgG4. Lectins can modulate IgE responses to other antigens [hG3 also does this, and there is some evidence that CD23 (the low-affinity IgE receptor) is in itself a C-type lectin. ...
Respiratory and systemic humoral and cellular immune responses
... The level of heterosubtypic immunity (Het-I) and the immune mechanisms stimulated by a heterosubtypic influenza virus infection were investigated in pigs. Pigs are natural hosts for influenza virus and, like humans, they host both subtypes H1N1 and H3N2. Marked Het-I was observed when pigs were infe ...
... The level of heterosubtypic immunity (Het-I) and the immune mechanisms stimulated by a heterosubtypic influenza virus infection were investigated in pigs. Pigs are natural hosts for influenza virus and, like humans, they host both subtypes H1N1 and H3N2. Marked Het-I was observed when pigs were infe ...
Sleep, the Immune System and the Common Cold
... disturbed sleep. Shift workers, parents of young children, menopausal women and the elderly represent groups that often sleep poorly or less than seems ideal in order to function at their best. Recent studies have shown that people are sleeping less across society as a whole (Jean-Louis et al, 2000) ...
... disturbed sleep. Shift workers, parents of young children, menopausal women and the elderly represent groups that often sleep poorly or less than seems ideal in order to function at their best. Recent studies have shown that people are sleeping less across society as a whole (Jean-Louis et al, 2000) ...
HIV ERADICATION:
... like HIV use their reverse transcriptase enzyme to copy their genetic material from RNA to DNA. Next, the integrase enzyme inserts these new DNA copies into the host cell’s chromosomes. Utilizing the cell’s own machinery, this proviral DNA blueprint is used to produce proteins which are assembled in ...
... like HIV use their reverse transcriptase enzyme to copy their genetic material from RNA to DNA. Next, the integrase enzyme inserts these new DNA copies into the host cell’s chromosomes. Utilizing the cell’s own machinery, this proviral DNA blueprint is used to produce proteins which are assembled in ...
- Royal College of Surgeons
... antigen presenting cells to the white cells in the immune system, the T-cells. And it is this presentation which forms the same process as the process by which bacteria and viruses are presented to the immune system. But you will see on the other side of the slide the direct allorecognition, this is ...
... antigen presenting cells to the white cells in the immune system, the T-cells. And it is this presentation which forms the same process as the process by which bacteria and viruses are presented to the immune system. But you will see on the other side of the slide the direct allorecognition, this is ...
Childhood Immune Maturation and Allergy Development: Regulation by Maternal
... insufficient induction of T cells with regulatory and/or Th1-like properties to counteract allergy-inducing Th2 response, may underlie the allergy epidemic 9-13. Most studies investigating the underlying mechanisms have focused on postnatal microbial exposure 14-18. An increasing body of evidence fr ...
... insufficient induction of T cells with regulatory and/or Th1-like properties to counteract allergy-inducing Th2 response, may underlie the allergy epidemic 9-13. Most studies investigating the underlying mechanisms have focused on postnatal microbial exposure 14-18. An increasing body of evidence fr ...
Medical monitoring: CD4 cell counts
... CD4 cell counts What is the CD4 count? Lymphocytes are a subgroup of the body’s white blood cells (leukocytes). CD4 cells are one type of lymphocyte and they co-ordinate the immune system’s response to certain micro-organisms, such as viruses. CD4 cells are the main cells in the body infected by HIV ...
... CD4 cell counts What is the CD4 count? Lymphocytes are a subgroup of the body’s white blood cells (leukocytes). CD4 cells are one type of lymphocyte and they co-ordinate the immune system’s response to certain micro-organisms, such as viruses. CD4 cells are the main cells in the body infected by HIV ...
Tumor Necrosis Factor and Alzheimer`s Disease
... converting enzyme (TACE, also known as ADAM-17) mediates release of TNF from the cell surface (45), but is involved in processing several cellmembrane-associated proteins, including TNF receptors, which are released by its action to produce soluble forms that can neutralize the actions of TNF (46). ...
... converting enzyme (TACE, also known as ADAM-17) mediates release of TNF from the cell surface (45), but is involved in processing several cellmembrane-associated proteins, including TNF receptors, which are released by its action to produce soluble forms that can neutralize the actions of TNF (46). ...
Immune responses to vaccines involving a combined antigen
... reported that sustained antigen release from poly(lactic-coglycolic acid) (PLGA) nanoparticles favored long-term effectormemory cellular responses [22], and Johansen et al. demonstrated that antigenic stimulation increasing exponentially over days induced more potent CD8þ T cell responses and antivi ...
... reported that sustained antigen release from poly(lactic-coglycolic acid) (PLGA) nanoparticles favored long-term effectormemory cellular responses [22], and Johansen et al. demonstrated that antigenic stimulation increasing exponentially over days induced more potent CD8þ T cell responses and antivi ...
What is ovarian cancer?
... that it uses the body’s own processes to destroy cancer cells, thus decreasing the sideeffect profile of the treatment compared to external chemotherapeutic agents; • Large opportunity: We believe the opportunity is large and likely to be reimbursed well. The World Health Organisation (WHO) predicts ...
... that it uses the body’s own processes to destroy cancer cells, thus decreasing the sideeffect profile of the treatment compared to external chemotherapeutic agents; • Large opportunity: We believe the opportunity is large and likely to be reimbursed well. The World Health Organisation (WHO) predicts ...
Peripheral blood mononuclear cells from severe asthmatic
... IL-4 by LPS-stimulated PBMC from severe asthmatic children. These results provide new evidence corroborating with recently published research demonstrating that low proliferative response to LPS and IL-4 production may constitute a risk factor for the development of asthma and a well-defined feature ...
... IL-4 by LPS-stimulated PBMC from severe asthmatic children. These results provide new evidence corroborating with recently published research demonstrating that low proliferative response to LPS and IL-4 production may constitute a risk factor for the development of asthma and a well-defined feature ...
Independent of IL-4 Development of Lupus in BXSB Mice Is
... Survival of IL-42/2 and wild-type BXSB mice BXSB background mice deficient in IL-4 expression and IL-41/1 and IL-41/2 littermate controls were produced by backcrossing IL-41/2 mice to the BXSB strain and then intercrossing the N7 generation. When the resulting wild-type and IL-42/2 mice were followe ...
... Survival of IL-42/2 and wild-type BXSB mice BXSB background mice deficient in IL-4 expression and IL-41/1 and IL-41/2 littermate controls were produced by backcrossing IL-41/2 mice to the BXSB strain and then intercrossing the N7 generation. When the resulting wild-type and IL-42/2 mice were followe ...
... diseases. In tuberculosis the recruited and activated peripheral blood monocyte plays a critical role in granuloma formation. In asbestosis, mononuclear phagocytes have been shown to release oxygen radicals. For example, macrophages may produce active oxygen radicals during unsuccessful phagocytosis ...
3 - bioRxiv
... loop-blocking on CD86 expression was constant along a wide spectrum of medium to high LPS doses, but absent at low LPS doses (green curve in Fig. 2B). The impact of the two opposite/contradictory loops differed not only in the directionality of the effect but also in mode of the effect: blocking the ...
... loop-blocking on CD86 expression was constant along a wide spectrum of medium to high LPS doses, but absent at low LPS doses (green curve in Fig. 2B). The impact of the two opposite/contradictory loops differed not only in the directionality of the effect but also in mode of the effect: blocking the ...
Leukocyte IGF-1 Receptor Expression during Muscle Recovery
... IMMUNE FUNCTION, COLD WATER IMMERSION, CRYOTHERAPY, RESISTANCE EXERCISE, INFLAMMATION ...
... IMMUNE FUNCTION, COLD WATER IMMERSION, CRYOTHERAPY, RESISTANCE EXERCISE, INFLAMMATION ...
Characterization of TLR2, NOD2, and related cytokines in mammary
... to subclinical bovine mastitis and tends to develop into persistent and chronic infections [3, 4]. Long-term infection causes reduced milk production, resulting in economic loss for dairy producers [5]. One possible mechanism of chronic infection is that the bacteria survive in the host phagocytes a ...
... to subclinical bovine mastitis and tends to develop into persistent and chronic infections [3, 4]. Long-term infection causes reduced milk production, resulting in economic loss for dairy producers [5]. One possible mechanism of chronic infection is that the bacteria survive in the host phagocytes a ...
Decreased Expression of Integrins by Hematopoietic Cells in
... disease? Br J Rheumatol. 1997;36:516-21. 21. Gracie JA, Koyama N, Murdoch J, Field M, McGarry F, Crilly A, Schobel A, Madhok R, Pons-Kuhnemann J, McInnes IB, Moller B. Disease association of two distinct interleukin-18 promotor polymorphisms in Caucasian rheumatoid arthritis patients. ...
... disease? Br J Rheumatol. 1997;36:516-21. 21. Gracie JA, Koyama N, Murdoch J, Field M, McGarry F, Crilly A, Schobel A, Madhok R, Pons-Kuhnemann J, McInnes IB, Moller B. Disease association of two distinct interleukin-18 promotor polymorphisms in Caucasian rheumatoid arthritis patients. ...