Author`s personal copy
... target cells include dendritic reticulum cells, monocytes, lymphocytes, hepatocytes, and vascular endothelial cells. Viral replication appears to occur in dendritic cells, monocytes, and possibly circulating lymphoid cells, and damage to these and other target cells occurs through immune-mediated me ...
... target cells include dendritic reticulum cells, monocytes, lymphocytes, hepatocytes, and vascular endothelial cells. Viral replication appears to occur in dendritic cells, monocytes, and possibly circulating lymphoid cells, and damage to these and other target cells occurs through immune-mediated me ...
- Future Medicine
... which can trigger the innate immune system to produce proinflammatory cytokines and chronic immune activation [3] . However, the pathogenesis of immune activation is complex and multifactorial. In addition to the translocation of microbial products, immune activation is believed to be driven by dire ...
... which can trigger the innate immune system to produce proinflammatory cytokines and chronic immune activation [3] . However, the pathogenesis of immune activation is complex and multifactorial. In addition to the translocation of microbial products, immune activation is believed to be driven by dire ...
Correlates with Immunodominance Markedly over the Course of
... daptive immune responses are central to the control and eradication of viruses. Abs inactivate viruses in fluid phase, thereby diminishing the number of host cells that become infected, and CD8⫹ T lymphocytes exert their effector functions on infected cells, limiting virus propagation and thus reduc ...
... daptive immune responses are central to the control and eradication of viruses. Abs inactivate viruses in fluid phase, thereby diminishing the number of host cells that become infected, and CD8⫹ T lymphocytes exert their effector functions on infected cells, limiting virus propagation and thus reduc ...
Thrombocytopenia: How Best to Determine the Cause
... Any one of a spectrum of viral infections—including rubella, influenza, and infectious mononucleosis—can cause a drop in platelet count. The decrease usually results from an immune mechanism brought on by the infection. However, platelet destruction that is immune-mediated also occurs independently ...
... Any one of a spectrum of viral infections—including rubella, influenza, and infectious mononucleosis—can cause a drop in platelet count. The decrease usually results from an immune mechanism brought on by the infection. However, platelet destruction that is immune-mediated also occurs independently ...
Product Information BACTIVATE
... BACTIVATE is a diagnostic enabling detection of chronic subclinical uterine infections associated with Strep zoo in mares. If a chronic infection with Strep zoo is present in the endometrium it will be activated when BACTIVATE is instilled in the uterus. Activated Strep zoo will thus become availabl ...
... BACTIVATE is a diagnostic enabling detection of chronic subclinical uterine infections associated with Strep zoo in mares. If a chronic infection with Strep zoo is present in the endometrium it will be activated when BACTIVATE is instilled in the uterus. Activated Strep zoo will thus become availabl ...
for T cell activation A
... activated. CD40 L binds to CD40 on DCs ( this will enhance the activation process by increasing the expression of B-7 on DC----Increase the second signal triggered by CD28 as more and more CD28 on T cells being activated bind to B 7 on DCs (Amplification of the second signal) 6. The first signal wit ...
... activated. CD40 L binds to CD40 on DCs ( this will enhance the activation process by increasing the expression of B-7 on DC----Increase the second signal triggered by CD28 as more and more CD28 on T cells being activated bind to B 7 on DCs (Amplification of the second signal) 6. The first signal wit ...
Acute Canine Gastroenteritis
... • Some of the above causes are LIFE-THREATENING diseases, while others may become self-limiting or chronic. Chronic disease can sometimes become life threatening. • Canine Parvovirus is a highly contagious virus and most commonly affects puppies. Parvovirus is spread through feces, and the virus can ...
... • Some of the above causes are LIFE-THREATENING diseases, while others may become self-limiting or chronic. Chronic disease can sometimes become life threatening. • Canine Parvovirus is a highly contagious virus and most commonly affects puppies. Parvovirus is spread through feces, and the virus can ...
The Very Young Patient - Advances in Inflammatory Bowel Diseases
... • Tested 160/163 adult-onset risk genotypes which explain ~ 20% of the genetic susceptibility • 1047 pediatric-onset IBD cases and 1663 healthy controls from RISK study • Replicated 88% CD and 90% UC variants • Sequencing approaches needed for more comprehensive dissection of known risk loci and dis ...
... • Tested 160/163 adult-onset risk genotypes which explain ~ 20% of the genetic susceptibility • 1047 pediatric-onset IBD cases and 1663 healthy controls from RISK study • Replicated 88% CD and 90% UC variants • Sequencing approaches needed for more comprehensive dissection of known risk loci and dis ...
Therapeutic potential of the immunomodulatory
... T-lymphocyte activation and proliferation assays were performed in the presence of both autologous and allogeneic human (Di Nicola et al., 2002), baboon (Bartholomew et al., 2002), and murine (Djouad et al., 2003) MSCs. These studies demonstrated that MSC were capable of suppressing both lymphocyte ...
... T-lymphocyte activation and proliferation assays were performed in the presence of both autologous and allogeneic human (Di Nicola et al., 2002), baboon (Bartholomew et al., 2002), and murine (Djouad et al., 2003) MSCs. These studies demonstrated that MSC were capable of suppressing both lymphocyte ...
PDF - Herbert Publications
... the innate immune system [11,12]. Innate IFN-γ production is mainly found in young animals, although older animals may also respond in a similar way [13]. ...
... the innate immune system [11,12]. Innate IFN-γ production is mainly found in young animals, although older animals may also respond in a similar way [13]. ...
Artículo de revisión The ocular surface: from physiology to the ocular
... The conjunctiva is a lining of the outer portion of the eye. Conjunctival tissue begins from the anterior portion of the limbus, and ends at the eyelids margin. Anatomically, conjunctiva is divided into three regions: i) the bulbar conjunctiva, which covers the anterior portion of the sclera; ii) th ...
... The conjunctiva is a lining of the outer portion of the eye. Conjunctival tissue begins from the anterior portion of the limbus, and ends at the eyelids margin. Anatomically, conjunctiva is divided into three regions: i) the bulbar conjunctiva, which covers the anterior portion of the sclera; ii) th ...
Salwa Hindawi MSc, MRCPath, CTM Medical Director of Blood
... patients developed anti-K while two (22.2%) had non-specific antibody. One patient developed anti-D (11.1%) and anti-E (11.1%). Two had anti-D (11.1%) and anti-C while the other one (11.1%) developed anti-E and anti-K. ...
... patients developed anti-K while two (22.2%) had non-specific antibody. One patient developed anti-D (11.1%) and anti-E (11.1%). Two had anti-D (11.1%) and anti-C while the other one (11.1%) developed anti-E and anti-K. ...
Vitamin D Concentrations are Decreased in Patients with Alopecia
... 8 (19%) patients with AA also had other autoimmune diseases. In the study, we found that AA has features of comorbidity autoimmune illness and family autoimmune history. Similarly, Kilic et al. showed that 17 (13,6%) patients with AA had other autoimmune diseases [14]. The association between AA and ...
... 8 (19%) patients with AA also had other autoimmune diseases. In the study, we found that AA has features of comorbidity autoimmune illness and family autoimmune history. Similarly, Kilic et al. showed that 17 (13,6%) patients with AA had other autoimmune diseases [14]. The association between AA and ...
Seminar Antiretroviral therapy and management of HIV infection
... jirovecii pneumonia, Kaposi’s sarcoma) or less than 50 cells per μL (eg, cytomegalovirus retinitis, CNS nonHodgkin’s lymphoma). Despite this classic and often predictable natural history, emphasis should be put on the fact that some serious complications such as bacterial pneumonia, Kaposi’s sarcoma ...
... jirovecii pneumonia, Kaposi’s sarcoma) or less than 50 cells per μL (eg, cytomegalovirus retinitis, CNS nonHodgkin’s lymphoma). Despite this classic and often predictable natural history, emphasis should be put on the fact that some serious complications such as bacterial pneumonia, Kaposi’s sarcoma ...
Immunohaematology - The Carter Center
... only 23 chromosomes not 46 as in the body cells. This process is called meiosis. However, during fortification when the egg and sperm unite, the fertilized ovum receives 23 chromosomes from each sex cell half of these from the male and half from the female and thus will contain 46 chromosomes which ...
... only 23 chromosomes not 46 as in the body cells. This process is called meiosis. However, during fortification when the egg and sperm unite, the fertilized ovum receives 23 chromosomes from each sex cell half of these from the male and half from the female and thus will contain 46 chromosomes which ...
Challenge Recovery from Secondary Poxvirus to Humoral Immunity
... requires the function of natural killer (NK) cells, granulocytes, plasmacytoid dendritic cells (pDC), T cells, and B cells. However, during a secondary challenge, resolution of infection is thought to be dependent on antibody but not T cell function. We investigated the contribution of NK cells, gra ...
... requires the function of natural killer (NK) cells, granulocytes, plasmacytoid dendritic cells (pDC), T cells, and B cells. However, during a secondary challenge, resolution of infection is thought to be dependent on antibody but not T cell function. We investigated the contribution of NK cells, gra ...
Pathogen evolution and the immunological niche
... not clearly related to immune escape.46 Similarly, the ability of herpesviruses to establish latent infections, inhibit MHC presentation, and move directly between cells could reduce selective pressure to escape from antibodies and CD8+ T cells. In these cases, escape from specific immune memory may ...
... not clearly related to immune escape.46 Similarly, the ability of herpesviruses to establish latent infections, inhibit MHC presentation, and move directly between cells could reduce selective pressure to escape from antibodies and CD8+ T cells. In these cases, escape from specific immune memory may ...
Distinct CD4 helper T cells involved in primary and
... and on day 39 cell numbers were determined by flow cytometry. In marked contrast to what was observed in the primary response, we found that LLO56 had a much larger recall response than LLO118 T cells (Fig. 1B). The same pattern was also seen at day 6 after rechallenge (Fig. S4A). To ascertain whethe ...
... and on day 39 cell numbers were determined by flow cytometry. In marked contrast to what was observed in the primary response, we found that LLO56 had a much larger recall response than LLO118 T cells (Fig. 1B). The same pattern was also seen at day 6 after rechallenge (Fig. S4A). To ascertain whethe ...
... Assuming that at least a doubling of the anti-B. burgdorferi seroprevalence in a sarcoidosis population is of immunopathogenetic relevance, the sample size of our study and control populations were large enough to ascertain such a difference, with a probability of error <0.05. The fact that a signif ...
Treatment of Patients with Refractory Giardiasis
... 2 sequential treatment regimens that consisted of tinidazole, 2 g given once followed by 500 mg given q.d. for 14 days, followed by a combination of tinidazole, 500 mg given q.d., and doxycycline, 100 mg given b.i.d., for 21 days. Before the commencement of each treatment regimen, stool samples test ...
... 2 sequential treatment regimens that consisted of tinidazole, 2 g given once followed by 500 mg given q.d. for 14 days, followed by a combination of tinidazole, 500 mg given q.d., and doxycycline, 100 mg given b.i.d., for 21 days. Before the commencement of each treatment regimen, stool samples test ...
HIV-specific antibody- dependent cellular cytotoxicity
... risk of acquisition and appeared to block a potentially protective role for ADCC antibodies. Thus, non-neutralizing ADCC antibodies are under intense interest as a potentially protective immune response to HIV. ADCC in HIV & SIV ...
... risk of acquisition and appeared to block a potentially protective role for ADCC antibodies. Thus, non-neutralizing ADCC antibodies are under intense interest as a potentially protective immune response to HIV. ADCC in HIV & SIV ...