Japanese Journal of Ophthalmology Vol.46 No.1
... (AMD).6,7 Because AMD is going to be the major focus for RPE transplantation, it is imperative to formulate an immunosuppressive strategy. The long-term aim of this pilot study is to develop a specific immunosuppressive method to suppress graft rejection. For this we needed to establish a positive c ...
... (AMD).6,7 Because AMD is going to be the major focus for RPE transplantation, it is imperative to formulate an immunosuppressive strategy. The long-term aim of this pilot study is to develop a specific immunosuppressive method to suppress graft rejection. For this we needed to establish a positive c ...
Antigen Recognition by T Lymphocytes
... * T-cell and B-cell receptors recognize different antigens * B-cells recognize * Intact protein, carbohydrate and lipid molecules on bugs and soluble ...
... * T-cell and B-cell receptors recognize different antigens * B-cells recognize * Intact protein, carbohydrate and lipid molecules on bugs and soluble ...
Critical Review A role for anti-HSP60 antibodies in arthritis: a critical review
... the role of HSP60 in the development of arthritis in addition to antiHSP60, serology should include a more functional study on how HSP60 can reach the extracellular locations and whether it is tolerogenic. Second, studies are needed on how the different subclasses of IgG-specific human HSP60 may sti ...
... the role of HSP60 in the development of arthritis in addition to antiHSP60, serology should include a more functional study on how HSP60 can reach the extracellular locations and whether it is tolerogenic. Second, studies are needed on how the different subclasses of IgG-specific human HSP60 may sti ...
- Wiley Online Library
... The protozoan parasites Leishmania spp. are known to infect a variety of mammalian hosts and causes diseases ranging from localized cutaneous to systemic visceral forms [1]. Experimental cutaneous mouse leishmaniasis is widely used as a model for this parasitic disease. After the subcutaneous (s.c.) ...
... The protozoan parasites Leishmania spp. are known to infect a variety of mammalian hosts and causes diseases ranging from localized cutaneous to systemic visceral forms [1]. Experimental cutaneous mouse leishmaniasis is widely used as a model for this parasitic disease. After the subcutaneous (s.c.) ...
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... infection [14]. They distinguished three treatment groups: all animals in the group treated with 1,75 mg OM-85/mouse has survived, compared to 70% surviving in the group treated with 0,175 mg/mouse and the untreated control group; treated animals presented with milder clinical symptoms in respect to ...
... infection [14]. They distinguished three treatment groups: all animals in the group treated with 1,75 mg OM-85/mouse has survived, compared to 70% surviving in the group treated with 0,175 mg/mouse and the untreated control group; treated animals presented with milder clinical symptoms in respect to ...
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... are present as ‘immature’ cells in peripheral tissues, especially tissues that are exposed to the external environment, including the skin, lungs and intestine. They are also present in lymphoid tissues, including the lymph nodes and spleen. To migrate to these locations, DCs travel via the blood or ...
... are present as ‘immature’ cells in peripheral tissues, especially tissues that are exposed to the external environment, including the skin, lungs and intestine. They are also present in lymphoid tissues, including the lymph nodes and spleen. To migrate to these locations, DCs travel via the blood or ...
In Vitro Antigen-induced Antibody Responses to Hepatitis B Surface
... Thomas R. Cupps, John L. Gerin, Robert H. Purcell, Paul K. Goldsmith, and Anthony S. Fauci ...
... Thomas R. Cupps, John L. Gerin, Robert H. Purcell, Paul K. Goldsmith, and Anthony S. Fauci ...
Cellular-mediated and humoral immunity in children with autism
... novel targets for treatment8. There have been numerous findings of altered immune function in autism, numerous attempts at determining susceptibility genes through a number of studies have indicated that multiple genes, including immune related genes, may be associated with autism9,10. Studies have ...
... novel targets for treatment8. There have been numerous findings of altered immune function in autism, numerous attempts at determining susceptibility genes through a number of studies have indicated that multiple genes, including immune related genes, may be associated with autism9,10. Studies have ...
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... PowerPoint® Lecture Slide Presentation prepared by Christine L. Case Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings ...
... PowerPoint® Lecture Slide Presentation prepared by Christine L. Case Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings ...
the complement system
... of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system. The complement sy ...
... of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system. The complement sy ...
Fontana & Vance (2011) Imm Rev
... investigation. In contrast to the relatively tidy and organized process of apoptotic cell death, pyroptosis is also associated with the uncontrolled release of cellular contents, some of which appear to promote inflammatory responses. The inflammatory mediators not only include cytokines processed d ...
... investigation. In contrast to the relatively tidy and organized process of apoptotic cell death, pyroptosis is also associated with the uncontrolled release of cellular contents, some of which appear to promote inflammatory responses. The inflammatory mediators not only include cytokines processed d ...
Systems biology in vaccine design
... determining factors of high-affinity antibody responses and efficient immune memory. Different types of memory T cells (central-memory and effector-memory) have been identified based on their functional and migratory properties and therefore contribute differently to the long-lasting cellular immuni ...
... determining factors of high-affinity antibody responses and efficient immune memory. Different types of memory T cells (central-memory and effector-memory) have been identified based on their functional and migratory properties and therefore contribute differently to the long-lasting cellular immuni ...
Summary of recent significant findings in ME-cfs research
... autoimmunity by inhibiting apoptotic and stimulating necrotic cell death pathways and hence decreasing immunosuppression at the termination of the immune response and increasing inflammation. Elevated levels of pro-inflammatory and other cytokine species conspire together to impair the normal homeos ...
... autoimmunity by inhibiting apoptotic and stimulating necrotic cell death pathways and hence decreasing immunosuppression at the termination of the immune response and increasing inflammation. Elevated levels of pro-inflammatory and other cytokine species conspire together to impair the normal homeos ...
The potential “bad guys”
... “Helps” other cells (operations commander); produces various cytokines that activate presenting cell and direct other cells Recognizes antigen presented by Major Histocompatibility Complex (MHC) Class II Exogenous proteins (i.e. those that have been taken up by the cell) are presented Found on antig ...
... “Helps” other cells (operations commander); produces various cytokines that activate presenting cell and direct other cells Recognizes antigen presented by Major Histocompatibility Complex (MHC) Class II Exogenous proteins (i.e. those that have been taken up by the cell) are presented Found on antig ...
Federica Chessa Dr. sc. hum. Dendritic cell function in different renal
... from 300 mOsm/L in the cortex up to 1200 mOsm/L in the inner medulla. A major contribution to the strong osmolarity increase in medulla is given by interstitial sodium. An aspect so far not investigated is whether non-immunologic biophysical factors within the kidney, such as medullary hyperosmolari ...
... from 300 mOsm/L in the cortex up to 1200 mOsm/L in the inner medulla. A major contribution to the strong osmolarity increase in medulla is given by interstitial sodium. An aspect so far not investigated is whether non-immunologic biophysical factors within the kidney, such as medullary hyperosmolari ...
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... are a major cell type in lung tissue, and most of these cells exist in the pulmonary alveolus.15 It involves in both the innate and adaptive immune responses and may be one of the major sources of IL-13 in mouse models of asthma.16 Furthermore, activation of alveolar macrophages by the cytokines res ...
... are a major cell type in lung tissue, and most of these cells exist in the pulmonary alveolus.15 It involves in both the innate and adaptive immune responses and may be one of the major sources of IL-13 in mouse models of asthma.16 Furthermore, activation of alveolar macrophages by the cytokines res ...
Development of a fast release immunomodulated vaccine against FMD virus. Induced immunity
... Animals: adult mice BALB/c and N/NIH(S) nude strain, bovines and pigs negative to FMDV. All the experiments were performed under the international rules of animal welfare. Virus: inactivated FMDV strain O1Campos was used for vaccine formulations and ELISA tests. Viral challenge was performed with in ...
... Animals: adult mice BALB/c and N/NIH(S) nude strain, bovines and pigs negative to FMDV. All the experiments were performed under the international rules of animal welfare. Virus: inactivated FMDV strain O1Campos was used for vaccine formulations and ELISA tests. Viral challenge was performed with in ...
PDF - The Journal of Immunology
... system. For example, the MHC class I-like molecule MIC is induced on the surface of heat-shocked or otherwise stressed cells, and has been shown to bind to an activating receptor called NKG2D, which is expressed by ␥␦ T cells, CD8⫹ T cells, and NK cells (37). Heat shock proteins themselves appear to ...
... system. For example, the MHC class I-like molecule MIC is induced on the surface of heat-shocked or otherwise stressed cells, and has been shown to bind to an activating receptor called NKG2D, which is expressed by ␥␦ T cells, CD8⫹ T cells, and NK cells (37). Heat shock proteins themselves appear to ...
B Lymphocytes in Cancer Immunology
... memory B cells undergo class-switching in the germinal center, down-regulate IgM expression, use one of the IgG subtypes, IgA, or IgE genes to form the heavy chain of their antigen receptor, and ultimately recognize protein antigens under the control of helper T cells (Fig. 2.1). ...
... memory B cells undergo class-switching in the germinal center, down-regulate IgM expression, use one of the IgG subtypes, IgA, or IgE genes to form the heavy chain of their antigen receptor, and ultimately recognize protein antigens under the control of helper T cells (Fig. 2.1). ...
S flexneri
... • Observed suppression of transcription of genes mainly coding for antimicrobial peptides, like β-defensin (e.g., hBD-3), in these cell lines • MxiE (bacterial regulator) is responsible for such regulatory process In vivo studies – • Human intestinal xenotransplants were used as model, infected with ...
... • Observed suppression of transcription of genes mainly coding for antimicrobial peptides, like β-defensin (e.g., hBD-3), in these cell lines • MxiE (bacterial regulator) is responsible for such regulatory process In vivo studies – • Human intestinal xenotransplants were used as model, infected with ...
CONTRIBUTIONS OF MEMORY B CELLS TO SECONDARY
... The first hypothesis implies that long-lived resting memory B cells account for the memory (Coffman et al., 1977; Hood et al., 1984; Jerne, 1984; Yefenof et al., 1985; Lane et al., 1986; Berek et al., 1987; Levy and Coutinho, 1987; Liu et al., 1988). It assumes that in the primary response, a small ...
... The first hypothesis implies that long-lived resting memory B cells account for the memory (Coffman et al., 1977; Hood et al., 1984; Jerne, 1984; Yefenof et al., 1985; Lane et al., 1986; Berek et al., 1987; Levy and Coutinho, 1987; Liu et al., 1988). It assumes that in the primary response, a small ...