Chapter 1: General introduction - UvA-DARE
... of mycorrhiza, in which nutrients are shared among the partners [3]. Selected fungi are also appreciated for their industrial potential, especially baker’s yeast, Saccharomyces cerevisiae, and some filamentous fungi such as Aspergillus niger. Fermentation carried out by S. cerevisiae is essential fo ...
... of mycorrhiza, in which nutrients are shared among the partners [3]. Selected fungi are also appreciated for their industrial potential, especially baker’s yeast, Saccharomyces cerevisiae, and some filamentous fungi such as Aspergillus niger. Fermentation carried out by S. cerevisiae is essential fo ...
Role of Estrogen nuclear receptor (ER) in T helper cells
... Multiple studies have demonstrated that estrogen (17β Estradiol) affects innate and adaptive immune systems. Its role as protective factor has been implicated in autoimmune diseases such as multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus. Estrogen exerts its action on immun ...
... Multiple studies have demonstrated that estrogen (17β Estradiol) affects innate and adaptive immune systems. Its role as protective factor has been implicated in autoimmune diseases such as multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus. Estrogen exerts its action on immun ...
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... channel activity, the production and secretion of significant amounts of mature IL-1β have been observed after treatment with high concentrations of extracellular ATP, even under acidic extracellular conditions. We found that P2X7R activation by ATP triggered the caspase-1dependent production and se ...
... channel activity, the production and secretion of significant amounts of mature IL-1β have been observed after treatment with high concentrations of extracellular ATP, even under acidic extracellular conditions. We found that P2X7R activation by ATP triggered the caspase-1dependent production and se ...
CD4 § T-Cells from Mice Immunized to
... T-cells cultured without DC; pulsed irradiated DC cultured without CD4 + T-cells; each CD4 + T-cell group with 3/xg/ml PHA (Sigma); each CD4 + T-cell group sham-pulsed (i.e., cultured in CM only); each DC group with fresh BALB/c (allogeneic) CD4 + T-cells; each DC group with fresh naive C57BL/6 (syn ...
... T-cells cultured without DC; pulsed irradiated DC cultured without CD4 + T-cells; each CD4 + T-cell group with 3/xg/ml PHA (Sigma); each CD4 + T-cell group sham-pulsed (i.e., cultured in CM only); each DC group with fresh BALB/c (allogeneic) CD4 + T-cells; each DC group with fresh naive C57BL/6 (syn ...
Dangerous exercise: lessons learned from dysregulated
... regional and systemic acidosis (149), heat (57), and reduced PO2 (117), all of which can stimulate factors like HIF (52, 61). Whether chronic inflammation associated with sports injuries leads to a similar transformation in immune cells such as occurs in chronic lung disease or RA is not known. Clea ...
... regional and systemic acidosis (149), heat (57), and reduced PO2 (117), all of which can stimulate factors like HIF (52, 61). Whether chronic inflammation associated with sports injuries leads to a similar transformation in immune cells such as occurs in chronic lung disease or RA is not known. Clea ...
Primary B-Cell Deficiencies Reveal a Link between Human IL
... We evaluated, for the first time, the frequency of circulating Th17 cells in CVID. Our CVID cohort (Table 1) featured the characteristic impairment of GC organization and generation of B-cell memory, demonstrated by the striking decrease in the frequency of switched-memory B cells, accumulation of C ...
... We evaluated, for the first time, the frequency of circulating Th17 cells in CVID. Our CVID cohort (Table 1) featured the characteristic impairment of GC organization and generation of B-cell memory, demonstrated by the striking decrease in the frequency of switched-memory B cells, accumulation of C ...
Lymphocytic hypophysitis: a rare or underestimated disease?
... cases it can induce acute secondary hyposurrenalism as the first appearance of the disease, with high mortality of affected patients (27, 71). LYH can also cause thyrotropin (TSH) and/or gonadotropin deficiencies (which are usually misdiagnosed when LYH affects women in pregnancy or in the postpartu ...
... cases it can induce acute secondary hyposurrenalism as the first appearance of the disease, with high mortality of affected patients (27, 71). LYH can also cause thyrotropin (TSH) and/or gonadotropin deficiencies (which are usually misdiagnosed when LYH affects women in pregnancy or in the postpartu ...
Induction of IgA Circulating Immune Complexes after
... mechanism by which wheat induces the skin and gut disease is unknown. Previous studies in our laboratories demonstrated the presence of IgA circulating immune complexes (CIC) in the sera of patients with DH [7,8]. This has been confirmed by Hall et a] [9] and a prevalence of approximately 30% is acc ...
... mechanism by which wheat induces the skin and gut disease is unknown. Previous studies in our laboratories demonstrated the presence of IgA circulating immune complexes (CIC) in the sera of patients with DH [7,8]. This has been confirmed by Hall et a] [9] and a prevalence of approximately 30% is acc ...
Activation of a Nonclassical NKT Cell Subset in a Transgenic
... One of the challenges in understanding viral pathogenesis is the elucidation of the full repertoire of immune responses that control the replication of the invading pathogen. Generally speaking, such control mechanisms can be either noncytocidal or cytocidal. Noncytocidal responses can result from t ...
... One of the challenges in understanding viral pathogenesis is the elucidation of the full repertoire of immune responses that control the replication of the invading pathogen. Generally speaking, such control mechanisms can be either noncytocidal or cytocidal. Noncytocidal responses can result from t ...
Clinical features and pathobiology of Ebolavirus
... the monocyte/macrophage/dendritic cell lineage (fever, TNF-a, cytokine storms, etc.) to the coagulopathy (complement activation, endothelial cell dysfunction and vascular leakage) and the failure of the liver (hepatocellular necrosis and failure to synthesize coagulation factors and DIC). With regar ...
... the monocyte/macrophage/dendritic cell lineage (fever, TNF-a, cytokine storms, etc.) to the coagulopathy (complement activation, endothelial cell dysfunction and vascular leakage) and the failure of the liver (hepatocellular necrosis and failure to synthesize coagulation factors and DIC). With regar ...
Inhibitory receptors on myeloid cells: New targets for therapy?
... combination of signals from cell surface receptors, intracellular signaling intermediates and gene transcription (Daeron et al., 2008). Historically, studies on the immune system have been largely concentrated on pathways that activate immune cell function in response to antigens and pathogens. Howe ...
... combination of signals from cell surface receptors, intracellular signaling intermediates and gene transcription (Daeron et al., 2008). Historically, studies on the immune system have been largely concentrated on pathways that activate immune cell function in response to antigens and pathogens. Howe ...
... and cathelicidins (30). AMP are secreted mainly by epithelial cells and neutrophils, but other cells may contribute to their production. These molecules are involved in disruptive interactions with the bacterial membrane (13, 14). AMP also have roles as mediators of inflammation, with effects on epi ...
Allergies ADVANCES Quercetin - Rosemary - Perilla -
... heated.54 However, more research is needed to confirm those results as they have not been reproduced by other researchers.55 Since foods that are introduced at a young age are more likely to be candidates for allergies, the American Academy of Pediatrics has recommended that children should not cons ...
... heated.54 However, more research is needed to confirm those results as they have not been reproduced by other researchers.55 Since foods that are introduced at a young age are more likely to be candidates for allergies, the American Academy of Pediatrics has recommended that children should not cons ...
Th17 responses to Mycobacterium tuberculosis are compromised in
... of M. tuberculosis. The profile of Th cell responses was analysed by ELISPOT in the lungs of ...
... of M. tuberculosis. The profile of Th cell responses was analysed by ELISPOT in the lungs of ...
Restoring the Balance of the Autonomic Nervous System as an
... the adrenal gland or nerve tissue and act as sympathomimetic hormones or neurotransmitters. In response to a stimulus, most sympathetic postganglionic neurons release NE, which subsequently activates adrenergic receptors (ARs) on the peripheral target tissue. There are two adrenergic receptor types ...
... the adrenal gland or nerve tissue and act as sympathomimetic hormones or neurotransmitters. In response to a stimulus, most sympathetic postganglionic neurons release NE, which subsequently activates adrenergic receptors (ARs) on the peripheral target tissue. There are two adrenergic receptor types ...
Answers
... – ______________: Interrupts the ability of the HIV virus to make copies of itself in the early stages of infection (AZT, 3TC, Epivir, Sustiva) – ______________: Interrupts the ability of the HIV virus to make copies of itself in later stages of infection (Norvir, Invirase, Crixivan, Kaletra, Reyata ...
... – ______________: Interrupts the ability of the HIV virus to make copies of itself in the early stages of infection (AZT, 3TC, Epivir, Sustiva) – ______________: Interrupts the ability of the HIV virus to make copies of itself in later stages of infection (Norvir, Invirase, Crixivan, Kaletra, Reyata ...
T Cell Receptor (TCR)
... - Class-I MHC => peptides from cytosolic (intracellular) proteins => CD8 T cells - Class-II MHC => peptides from extracellular (exogenous) proteins from phagocytosis => CD4 T cells 3. APCs serve two key functions for T cell activation: 1st function => process & present Ag peptides w/MHC to T cells ...
... - Class-I MHC => peptides from cytosolic (intracellular) proteins => CD8 T cells - Class-II MHC => peptides from extracellular (exogenous) proteins from phagocytosis => CD4 T cells 3. APCs serve two key functions for T cell activation: 1st function => process & present Ag peptides w/MHC to T cells ...
Sepsis Project Presentation 3744KB Jan 14 2015 08:21:43 AM
... In otherwise healthy individuals, the mortality rate for sepsis is 5% If severe sepsis develops, mortality rises sharply If hypotension (the hallmark of septic shock) is present, mortality rises to 50% ...
... In otherwise healthy individuals, the mortality rate for sepsis is 5% If severe sepsis develops, mortality rises sharply If hypotension (the hallmark of septic shock) is present, mortality rises to 50% ...
... of genes encoding cytokines and co-stimulatory molecules that regulate adaptive responses. Aims: The overall aim here was to examine how the developing immune system in young children is affected by microbial exposure. This was investigated in blood samples from children participating in a prospecti ...