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When gene marriages don`t work out: divorce by subfunctionalization
When gene marriages don`t work out: divorce by subfunctionalization

... copies after gene duplication – provides an attractive explanation for why so many duplicated genes exist in eukaryotes, without requiring each duplication event to have conferred a selective advantage [1]. For many duplicated genes, however, it has been difficult to pinpoint different subfunctions ...
8.
8.

... Lineage-specific expansion of a paralogous gene family: An increase in the number of paralogs as a result of one or more duplications that have occurred after the separation of a given lineage from other compared lineages. Lineage-specific expansions often reflect adaptations to a specific ecologica ...
Overlapping gene structure of human VLCAD and
Overlapping gene structure of human VLCAD and

... 6 at 11B3 – B4 in a head-to-head orientation. In contrast to the human genes, the mouse genes do not overlap and contain a gap of 3.48 kb between them. This suggests that the VLCAD and DLG4 genes were originally separated but have become co-localized during the course of evolution. Further analysis ...
Exploring biochemistry using metabolic pathways
Exploring biochemistry using metabolic pathways

Cross over frequency and gene mapping Notes
Cross over frequency and gene mapping Notes

... Crossing over –  ­ homologous chromosomes pair up during prophase I, they may exchange pieces of  chromosome ­ Linked genes do not always stay together in gamete formation ­ Crossing over results in new combinations of genes ­ Crossing over occurs during meiosis and cause linked genes to separate. ­ ...
Genetics of Color-Blindness
Genetics of Color-Blindness

... Prior Knowledge: For this activity to be meaningful, students need to understand sex-linked traits and how they are passed from parent to offspring. They also need to understand that a person who is a “carrier” for a sex-linked trait does not express the trait, but can pass the affected allele on to ...
Document
Document

... 3. A __________________ cross is one where you only deal with one trait. (MM x mm) 4. A dihybrid cross examines the inheritance of _______ different traits.( MMYy x mmYy) 5.Mendel’s 2nd law is the law of ___________________ __________________. It states that ____________ pairs __________________ ind ...
Towards Self- Change and Configuration
Towards Self- Change and Configuration

... • Less than 2 percent of the human genome is made up of protein-coding sequences • The rest labeled as ‘junk’ DNA – A lot of Registry entries are not configuration settings, but rather “operational states” such as usage counts, most recently used files, etc. – They can be labeled as ‘junk’ entries ...
Genomics
Genomics

... LIMITED LICENSE TO MODIFY. These PowerPoint® slides may be modified only by teachers currently teaching the Science and Global Issues SEPUP course to customize the unit to match their students’ learning levels or to insert additional teaching aides. Modified slides may be used only by the modifying ...
Overview of Articles for the literature talks Nr PMID Titel Date
Overview of Articles for the literature talks Nr PMID Titel Date

... determinants of nucleosome positioning. Although the search for underlying patterns encoded in nucleosomal DNA has been going on for about 30 years, our knowledge of these patterns still remains limited. Based on our evaluations of DNA deformation energy, we developed new scoring functions to predic ...
Sequencing the Human Genome
Sequencing the Human Genome

... HPG: Nature. In addition, newly sequenced sections were made public on the web within 24 hours of sequencing. Celera: Science. Celera’s intention is to sell or patent further information about the human genome. ...
Overview of Articles for the literature talks Nr PMID Titel Date
Overview of Articles for the literature talks Nr PMID Titel Date

... Signaling pathways invoke interplays between forward signaling and feedback to drive robust cellular response. In this study, we address the dynamics of growth factor signaling through profiling of protein phosphorylation and gene expression, demonstrating the presence of a kinetically defined clus ...
1st_pres_Geneprediction
1st_pres_Geneprediction

... are known to be ongoing (www.genomesonline.org). ...
Barron`s Ch 7 ppt Heredity
Barron`s Ch 7 ppt Heredity

... Tetraploid: Organism with (4n) Polyploid: Organism with extra sets of chromosomes - Common in plants - Results in abnormally large size plants - Some cases: responsible for new species E.g Triploid: Extra set of chromosomes (3n) Strawberries (8n) ...
Outline Why? Fold change Statistical testing with the t-test
Outline Why? Fold change Statistical testing with the t-test

Lecture #6 PPT
Lecture #6 PPT

... • Insect (mountain pine beetle ) outbreaks. When populations of this insect become large they attack healthy trees as well. Effect of WPBT and mountain pine beetle is more than the sum of the two • Dothistroma needle blight can cause outbreaks, however both Dothistroma and insect outbreaks may be cy ...
Genome duplication, divergent resolution and
Genome duplication, divergent resolution and

... and medaka have almost twice as many Hox clusters as, for example, humans. Additional evidence favouring the fish-specific genome duplication hypothesis comes from comparative mapping studies, which have identified a large number of mammalian genes with two zebrafish ‘co-orthologs’19–21. Furthermore ...
Horizontal and Vertical Gene Transfer
Horizontal and Vertical Gene Transfer

The BCM Microarray Core Facility
The BCM Microarray Core Facility

... The Microarray Core Facility (MCF) at Baylor College of Medicine provides investigators with access to a variety of state-of-the-art technologies and approaches that will enhance discovery for their genomic research. We house instrumentation supporting Affymetrix, Agilent, NimbleGen, Luminex, and Il ...
Figure 4.1
Figure 4.1

... dead ends of evolution Pseudogenes (Ψ) : Some DNA sequences that are related to those of the functional genes, but that cannot be translated into a functional protein. ...
View “Heal, Feed, Sustain”
View “Heal, Feed, Sustain”

... Monday, April 17, 2017 Tuesday, April 18, 2017 ...
12-5 Gene Regulation - Lincoln Park High School
12-5 Gene Regulation - Lincoln Park High School

... When is the repressor protein bound to the operator? When lactose is not present Can transcription occur when the repressor is bound to the operator? No Why or why not? The repressor protein blocks RNA polymerase from binding to the promoter How does the presence of lactose help start transcription ...
GENE REGULATION IN HIGHER ORGANSIMS Although eukaryotes
GENE REGULATION IN HIGHER ORGANSIMS Although eukaryotes

Section 2: Energy Flow in Ecosystems
Section 2: Energy Flow in Ecosystems

... Write the name of a fruit or vegetable that you don’t like to eat and explain why you don’t like it. Then write about ways in which the fruit or vegetable could possibly be changed by genetic engineering so that you would like it. ...
BCH364C-391L_Phenologs_Spring2015
BCH364C-391L_Phenologs_Spring2015

... Phenologs = significantly overlapping sets of orthologous genes, such that each gene in a given set gives rise to the same phenotype in that organism (e.g., human) ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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