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The 43 strains contain deletions that extend from the immunity
The 43 strains contain deletions that extend from the immunity

... does this experiment select for? The prototrophs are the result of excision at attL and attR restoring the integrity of the trpC gene. The colonies that are still auxotrophs are the result of aberrant spontaneous excision events. (These events could originate in the prophage and extend either leftwa ...
Genome browser - Indiana University
Genome browser - Indiana University

... • Current data set – 1 SNP every 279 bp A much more complete variation resource by which the genome-wide map can evaluated ...
Expansion of specialized metabolism
Expansion of specialized metabolism

... duplication (SSD) (Tamate et al. 2014), is more plausible for explanation of this phenomenon because WGD significantly increases the gene number across a whole genome, whereas LTD partly affects the gene number in a genome for duplication of restricted region of a genome. Indeed, excessive gene gain ...
Bioinformatics for Microarray Studies
Bioinformatics for Microarray Studies

...  GeneSpring – microarray data analysis  Spotfire – microarray data analysis and data ...
Dow, Graham: The limitation of genome wide association studies
Dow, Graham: The limitation of genome wide association studies

... genome.
 From
 an
 evolutionary
 perspective,
 the
 lack
 of
 strong,
 common
 variants
 in
 expressed
genes
makes
sense;
one
should
expect
that
such
variants
be
selected
against
in
 the
population.

The
area
surrounding
an
intergenic
SNP
can
be
quite
large
depending
on
 the
 number
 of
 SNPs
 used
 ...
I. The Emerging Role of Genetics and Genomics in Medicine
I. The Emerging Role of Genetics and Genomics in Medicine

... 6. Mode of inheritance refers to whether a trait is dominant or recessive, autosomal or carried on a sex chromosome. 7. An autosomal condition is equally likely to affect either sex. 8. X-linked characteristics affect males much more than females. 9. Recessive conditions can skip a generation becaus ...
the Highest Connected Isoforms
the Highest Connected Isoforms

... Considerations for multi-omics data integration Michael Tress CNIO, ...
Mouse Strain and Genetic Nomenclature
Mouse Strain and Genetic Nomenclature

Introduction to microarry
Introduction to microarry

mc2 Genome_Organization
mc2 Genome_Organization

... • Genes vary greatly in size and intron/exon organization. • Some genes don’t have any introns. Most common example is the histone genes. Histones are the proteins DNA gets wrapped around in the lowest unit of chromosomal organization, the nucleosome. • Some genes are quite huge: dystrophin (associa ...
Studying Genomes
Studying Genomes

... Full genome sequencing Full genome sequencing involves sequencing not only nuclear DNA, but also the DNA contained within mitochondria and chloroplasts. With this vast quantity of information, comparisons can be made between individuals of the same species and between different species. This gives ...
Chloroplast genes for components of the ATP synthase complex
Chloroplast genes for components of the ATP synthase complex

Slide 1
Slide 1

... Electroporation is a genetic transformation process in which a strong electric field is used to introduce DNA into cells. Bacterial transformation is important for molecular cloning, gene construct selection, and plasmid production and storage. To optimize the electroporation process, several key pa ...
Whole Exome Sequencing
Whole Exome Sequencing

... This session is estimated to encompass approximately 1-2% of the genome yet contains approximately 85% of disease-causing mutations. With the ability to sequence nearly the entire coding region of the human genome, it is possible for clinicians and clinical laboratories to use this information to id ...
Expressed Sequence Tags: Any Prior Art Effect?
Expressed Sequence Tags: Any Prior Art Effect?

... suggest its homologs because homologs often have similar properties and therefore chemists of ordinary skill would ordinarily contemplate making them to try to obtain compounds with improved properties. Similarly, a known compound may suggest its analogs or isomers, either geometric isomers . . . or ...
2. Organism`s level of realization of hereditary information
2. Organism`s level of realization of hereditary information

... The B/b gene determines the pigment color (B for black and b for brown). The epistatic C/c gene controls whether or not any pigment will be deposited in the hair. A homozygous recessive ccmouse has no hair pigment and is albino regardless of its B/bgenotype. ...
GENE GENE INTERACTION DOMINANCE
GENE GENE INTERACTION DOMINANCE

... It is also known as duplicate gene . When two gene pairs seem to be identical in function ,either dominant gene or both dominant gene together give the same effect. Such genes are called duplicate genes and the type of epistasis is called dominant epistasis. ...
Chromosomal assignment of seven genes on canine chromosomes
Chromosomal assignment of seven genes on canine chromosomes

Document
Document

... BLASTs to be performed and to speed the process, we downloaded the text or “flat file” of the TIGR rice protein sequences (available at: http://www.tigr.org/tdb/e2k1/osa1/data_download.shtml) and performed local blasts using blastall from NCBI (available at: http://www.ncbi.nlm.nih.gov/BLAST/downloa ...
Tomato genome annotation
Tomato genome annotation

... Unexpected expansion/reduction Fruit-specific expression ...
Chapter 10: Genes and Chromosomes
Chapter 10: Genes and Chromosomes

... specific place on a chromosome ...
Background Strain Characterization
Background Strain Characterization

... Evaluation of Backcrossing Using traditional backcrossing methods, 10 generations of backcrossing are required to establish congenic lines. Sometimes a desirable research model does not have the necessary documentation, the number of backcross generations has not been tracked, or the animals have b ...
9.
9.

... 10. Our data set of yeast protein-protein interactions was compiled from (7), the “core data” of (9), and 625 interactions identified by the two-hybrid array method [described in (8)] listed at http://depts. washington.edu/sfields/yplm/data/new2h.html. 11. Putative orthologs were defined as reciproc ...
An Investigation into the Genomic Evolution of the Histone Gene
An Investigation into the Genomic Evolution of the Histone Gene

... detail, but their role in concerted evolution is primarily based on theoretical and/or mathematical models with limited data from actual genome sequence to support them. It is the hypothesis of this research that if unequal crossing over is the main mechanism of concerted evolution, then the edges o ...
Multiple Investigator Recruitments in Genomics National Human
Multiple Investigator Recruitments in Genomics National Human

... description of proposed research, and contact information for three professional references through our online application system at https://irp-positions.nih.gov/apply/. Requests for letters of recommendation will be sent to your references when you submit your application. For more information on ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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