Methylation of an upstream Alu sequence on the Imprinted H19
... proposed experiment should reveal a better understanding of H19 Alu methylation and further our knowledge of genomic ...
... proposed experiment should reveal a better understanding of H19 Alu methylation and further our knowledge of genomic ...
Sulfuricella denitrificans gen. nov., sp. nov., a sulfur
... skB26T. In the phylogenetic analysis of the large subunit of form I RubisCO, encoded by the cbbL gene, the novel isolate clustered with beta- and gammaproteobacterial chemolithotrophs (Supplementary Fig. S1, available in IJSEM Online). A similar result was obtained from analysis of form II RubisCO, ...
... skB26T. In the phylogenetic analysis of the large subunit of form I RubisCO, encoded by the cbbL gene, the novel isolate clustered with beta- and gammaproteobacterial chemolithotrophs (Supplementary Fig. S1, available in IJSEM Online). A similar result was obtained from analysis of form II RubisCO, ...
Molecular tools for breeding basidiomycetes
... we have used the oyster mushroom Pleurotus ostreatus as a model system to study these three aspects. P. ostreatus is an edible basidiomycete that grows wildly on decaying wood thanks to its lignin-degrading capacity, and is industrially cultivated on a variety of substrates based on agricultural was ...
... we have used the oyster mushroom Pleurotus ostreatus as a model system to study these three aspects. P. ostreatus is an edible basidiomycete that grows wildly on decaying wood thanks to its lignin-degrading capacity, and is industrially cultivated on a variety of substrates based on agricultural was ...
Genomic signatures of diet-related shifts during human origins
... in the human genome [3,76 –79]. There are now many examples of recent adaptations in genes as well as in gene families that appear to be shaped by more recent diet-related pressures (e.g. taste [80,81] and olfactory [82] receptor genes). However, as reviewed above, as hominoids diverged from our las ...
... in the human genome [3,76 –79]. There are now many examples of recent adaptations in genes as well as in gene families that appear to be shaped by more recent diet-related pressures (e.g. taste [80,81] and olfactory [82] receptor genes). However, as reviewed above, as hominoids diverged from our las ...
Characterization of an IS-like element from
... frame (ORF) coding for a hypothetical protein with sequence homologies to proteins of known IS elements was identified (see below). The entire ORF was cloned by screening a M . tuberculosis library in A2001 (Vismara et al., 1990) using the cloned EcoRI fragment of the Agtl 1 library containing the O ...
... frame (ORF) coding for a hypothetical protein with sequence homologies to proteins of known IS elements was identified (see below). The entire ORF was cloned by screening a M . tuberculosis library in A2001 (Vismara et al., 1990) using the cloned EcoRI fragment of the Agtl 1 library containing the O ...
The importance of alternative splicing in the drug discovery process
... this activity resulted from a splice variant of the ERα that This approach was also employed to alter the alternative was not knocked out [29]. Thus, when trying to shut down splicing of the Tau gene that causes frontotemporal dethe activity of a gene, the knockout cassette should be inmentia and pa ...
... this activity resulted from a splice variant of the ERα that This approach was also employed to alter the alternative was not knocked out [29]. Thus, when trying to shut down splicing of the Tau gene that causes frontotemporal dethe activity of a gene, the knockout cassette should be inmentia and pa ...
- Covenant University Repository
... sequences. Stochastic optimisation methods, such as simulated annealing [9], Gibbs sampling [10] have been used on numerous occasions for multiple alignment but can be very slow and usually works well as an alignment improver in most cases i.e. when the method is given an alignment that is already c ...
... sequences. Stochastic optimisation methods, such as simulated annealing [9], Gibbs sampling [10] have been used on numerous occasions for multiple alignment but can be very slow and usually works well as an alignment improver in most cases i.e. when the method is given an alignment that is already c ...
Rec.DNA.BCH 446,31-32
... – Vector DNA functions to insert and amplify the DNA of intersit . • Vectors should contain an origin of replication – Enables the vector, together with the foreign DNA fragment inserted into it, to replicate • they contain one or more single (unique) restriction endonuclease sites that provide a ch ...
... – Vector DNA functions to insert and amplify the DNA of intersit . • Vectors should contain an origin of replication – Enables the vector, together with the foreign DNA fragment inserted into it, to replicate • they contain one or more single (unique) restriction endonuclease sites that provide a ch ...
Principals of General Zoology (Zoo-103)
... are referred to as homologous chromosome, or homologs. One member of each pair comes from each parent. Humans have 23 homologous chromosome pairs, which is often expressed as 2n=46. This expression indicate that humans are diploid (2n) and have a total of 46 chromosomes. The diploid chromosome num ...
... are referred to as homologous chromosome, or homologs. One member of each pair comes from each parent. Humans have 23 homologous chromosome pairs, which is often expressed as 2n=46. This expression indicate that humans are diploid (2n) and have a total of 46 chromosomes. The diploid chromosome num ...
A Genetic Linkage Map for the Zebrafish
... of making both haploid embryos and parthenogenetic diploid fish facilitate the identification and analysis of mutations (3). Saturating the genome with mutations that affect various aspects of the early development of zebrafish seems to be an attainable goal (2). The ability to make stable lines of ...
... of making both haploid embryos and parthenogenetic diploid fish facilitate the identification and analysis of mutations (3). Saturating the genome with mutations that affect various aspects of the early development of zebrafish seems to be an attainable goal (2). The ability to make stable lines of ...
Title: Genes in the Postgenomic Era Authors: Paul E. Griffiths and
... The autocatalytic synthesis of gene copies is more properly the function a whole DNA molecule (chromosome), and mutation and recombination are more properly the function of individual DNA nucleotides. This refined functional role was occupied by a specific physical structure – an 'open reading fram ...
... The autocatalytic synthesis of gene copies is more properly the function a whole DNA molecule (chromosome), and mutation and recombination are more properly the function of individual DNA nucleotides. This refined functional role was occupied by a specific physical structure – an 'open reading fram ...
sex chromosomes
... Used to make sex cells Meiosis halves the numbers of chromosomes Meiosis picks one chromosome from each pair at random and places them in a sex cell. This results in enormous variation amongst the sex cells. ...
... Used to make sex cells Meiosis halves the numbers of chromosomes Meiosis picks one chromosome from each pair at random and places them in a sex cell. This results in enormous variation amongst the sex cells. ...
Chromosome Research, 8:319-334
... between human and host chromosomes, although the rearrangement frequencies were relatively low (Nakagawa et al. 1996). To characterize them more precisely, we used WCP probes to determine the frequency of cells that retained the human chromosome. As shown in Table 1, a relatively high percentage of ...
... between human and host chromosomes, although the rearrangement frequencies were relatively low (Nakagawa et al. 1996). To characterize them more precisely, we used WCP probes to determine the frequency of cells that retained the human chromosome. As shown in Table 1, a relatively high percentage of ...
RNA-seq data analysis with Chipster
... Filtering vs trimming Filtering removes the entire read Trimming removes only the bad quality bases • It can remove the entire read, if all bases are bad Trimming makes reads shorter • This might not be optimal for some applications Paired end data: the matching order of the reads in the tw ...
... Filtering vs trimming Filtering removes the entire read Trimming removes only the bad quality bases • It can remove the entire read, if all bases are bad Trimming makes reads shorter • This might not be optimal for some applications Paired end data: the matching order of the reads in the tw ...
Notions of Biochemistry and Molecular Biology Manipulating DNA
... major band of supercoiled DNA with other fainter bands in the same lane. Note that by convention DNA gel is displayed with smaller DNA fragments near the bottom of the gel. This is because historically DNA were run vertically and the smaller DNA fragments ...
... major band of supercoiled DNA with other fainter bands in the same lane. Note that by convention DNA gel is displayed with smaller DNA fragments near the bottom of the gel. This is because historically DNA were run vertically and the smaller DNA fragments ...
Reebops - Kennesaw State University | College of Science and
... Each cell in all living organisms contains hereditary information that is encoded by a chemical called DNA (deoxyribonucleic acid). DNA is an extremely long molecule. When this long, skinny DNA molecule is all coiled up and bunched together it is called a chromosome. Each chromosome is a separate pi ...
... Each cell in all living organisms contains hereditary information that is encoded by a chemical called DNA (deoxyribonucleic acid). DNA is an extremely long molecule. When this long, skinny DNA molecule is all coiled up and bunched together it is called a chromosome. Each chromosome is a separate pi ...
Bioinformatic Resources, Challenges, and
... Genes can be searched by open reading frame name, gene symbol, full name, or product name. In addition, gene searching can be limited to those genes whose structures have been experimentally determined, cloned, and/or sequenced. In addition to restricting searches by these features, all three custom ...
... Genes can be searched by open reading frame name, gene symbol, full name, or product name. In addition, gene searching can be limited to those genes whose structures have been experimentally determined, cloned, and/or sequenced. In addition to restricting searches by these features, all three custom ...
Unit 12 Handout - Chavis Biology
... 2. You will now simulate the activity of EcoRI. Scan along the DNA sequence of strip 1 until you find the EcoRI restriction site. You’ll have to look at your notes to see where on the DNA EcoRI cutes. Using scissors make a cut through the DNA to simulate the action of the EcoRI restriction enzyme. S ...
... 2. You will now simulate the activity of EcoRI. Scan along the DNA sequence of strip 1 until you find the EcoRI restriction site. You’ll have to look at your notes to see where on the DNA EcoRI cutes. Using scissors make a cut through the DNA to simulate the action of the EcoRI restriction enzyme. S ...
Document
... Utilise known structure/function information to infer facts related to the predicted protein sequence Provide users with results from a number of standard algorithms/searches Provide users with cross-references (dbxrefs) to other resources Assign a simple one line description for each gene product ...
... Utilise known structure/function information to infer facts related to the predicted protein sequence Provide users with results from a number of standard algorithms/searches Provide users with cross-references (dbxrefs) to other resources Assign a simple one line description for each gene product ...
Document
... AS occurs in 59% of human genes (Graveley, 2001) AS expands protein diversity (generates from a single gene multiple transcripts) AS is tissue-specific (Graveley, 2001) AS is related to human diseases ...
... AS occurs in 59% of human genes (Graveley, 2001) AS expands protein diversity (generates from a single gene multiple transcripts) AS is tissue-specific (Graveley, 2001) AS is related to human diseases ...
epigenetika III
... from one parent and no copy from the other parent. Recall that normally a baby inherits one copy of each chromosome from his/her mother and one copy of each chromosome from his/ her father. In the rare circumstance of UPD a baby may have two copies of one of his/ her mother’s chromosome and no copie ...
... from one parent and no copy from the other parent. Recall that normally a baby inherits one copy of each chromosome from his/her mother and one copy of each chromosome from his/ her father. In the rare circumstance of UPD a baby may have two copies of one of his/ her mother’s chromosome and no copie ...
AP Biology
... Genes for antibiotic resistance = R Plasmids Role in rapid evolution Method for spreading “antibiotic resistance” ...
... Genes for antibiotic resistance = R Plasmids Role in rapid evolution Method for spreading “antibiotic resistance” ...
unit II - SP College
... of the sequence consisting of repetitive elements in human. Debates regarding the potential in vivo functions of these elements have been long standing. Controversial references to ‘junk’ or ‘selfish’ DNA were put forward early on, implying that repetitive DNA segments are remainders from past evolu ...
... of the sequence consisting of repetitive elements in human. Debates regarding the potential in vivo functions of these elements have been long standing. Controversial references to ‘junk’ or ‘selfish’ DNA were put forward early on, implying that repetitive DNA segments are remainders from past evolu ...
Deviations from Mendelian Genetics-Organelles
... chloroplasts produce energy for animals and plants. Each organelle contains a double stranded circular DNA molecule that encodes components of the mitochondrion or chloroplast. For example, mammalian mitochondrial DNA (mtDNA) is a 16 kbp DNA that encodes thirteen proteins involved in oxidative phosp ...
... chloroplasts produce energy for animals and plants. Each organelle contains a double stranded circular DNA molecule that encodes components of the mitochondrion or chloroplast. For example, mammalian mitochondrial DNA (mtDNA) is a 16 kbp DNA that encodes thirteen proteins involved in oxidative phosp ...
Human genome
The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.