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Chapter 4 - Fullfrontalanatomy.com
Chapter 4 - Fullfrontalanatomy.com

... The genetic material at the molecular level has to account for three important properties of inheritance. The genetic material must ...
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... …sticky ends with complementary base pairs can form hydrogen bonds, …DNA ligase: an enzyme that catalyzes the reformation of the phosphodiester bonds. ...
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Metagenomics: DNA sequencing of environmental samples
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... species and could revolutionize paleobiology. Our closest hominid relatives, the Neanderthals, diverged from modern humans roughly 500,000 years ago but survived until the late Pleistocene, and numerous Neanderthal remains of ages comparable to the ...
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Genome Annotation

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Analysis of Gene Silencing in Mammalian Cell Hybrids.
Analysis of Gene Silencing in Mammalian Cell Hybrids.

... differentially expressed genes between the FTO2B cell line and the FR cell line, excluding all genes not expressed in the FTO2B cells. Next, the chromosomal location of all genes represented greater than fivefold in the FR cells was found using a Rat Genome Database website. These genes were then ma ...
Unit 6 Student Notes - Flushing Community Schools
Unit 6 Student Notes - Flushing Community Schools

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Name: Pd.: ____ Section 11.1 The Work of Gregor Mendel (p. 308

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DNA Technology - wvhs.wlwv.k12.or.us
DNA Technology - wvhs.wlwv.k12.or.us

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Name: ____________ Pd.: ______ Date: Cells cannot make
Name: ____________ Pd.: ______ Date: Cells cannot make

... of amino acids which make up proteins) 4. The double helix structure explains how DNA can be replicated, or copied, but it does not explain how a gene works. Genes are coded DNA instructions that control the production of proteins within the cell. The first step in decoding these genetic messages is ...
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Text S1.
Text S1.

... the protein. The protein locations are relative to the protein sequence, but the exact protein sequence which is used as a reference is unknown. For genes with multiple transcripts (and hence multiple protein isoforms) or genes that have undergone protein sequence revision since the amino acid subst ...
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Endogenous retroviruses: Still active after all

... ancestor. One such provirus present in gorillas and chimpanzees, but not present in humans, provides evidence that some fraction of the former two species are more closely related to one another than to humans, even though the gorilla lineage diverged before separation of humans and chimps [19]. A s ...
Chapter 2: Applications of Biology
Chapter 2: Applications of Biology

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Practical Applications of DNA Technology
Practical Applications of DNA Technology

... techniques for combining genes from different sources invitro and transferring this recombinant DNA into a cell where it may be expressed.  First developed in 1975.  Resulted in the appearance of the biotechnology industry—the use of living organisms or their components to do practical tasks  Use ...
High-throughput genotyping
High-throughput genotyping

... are inherited together more often than could be expected based on allele frequencies • Two loci are inherited together, because recombination during meiosis separates them only seldom Finnish Genome Center ...
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Human genome



The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.
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