Alpha-1 Antitrypsin Deficiency
... The option for testing patients for alpha-1 antitrypsin is a sensitive issue. Certainly, ethical principles must be considered. It is essential that patients make an autonomous decision based on accurate information, including of the risks and benefits of knowing/not knowing. It is recommended that ...
... The option for testing patients for alpha-1 antitrypsin is a sensitive issue. Certainly, ethical principles must be considered. It is essential that patients make an autonomous decision based on accurate information, including of the risks and benefits of knowing/not knowing. It is recommended that ...
Cloning and characterization of CmGPD1, the Candida magnoliae
... well known that polyols are crucial to the osmoregulation of yeast as compatible solutes. When yeast cells are exposed to hyperosmotic stress, they accumulate one or more protective solutes such as glycerol, D-arabitol and mannitol. These polyols prevent the rapid diffusion of water from the cell in ...
... well known that polyols are crucial to the osmoregulation of yeast as compatible solutes. When yeast cells are exposed to hyperosmotic stress, they accumulate one or more protective solutes such as glycerol, D-arabitol and mannitol. These polyols prevent the rapid diffusion of water from the cell in ...
Investigation of the premelanosome protein
... The two identified SNPs were in linkage disequilibrium in the sequenced rabbits. Therefore we selected one of them (g.39510357G>A) for the analysis of the rabbit families in which there was segregation of blue and black coat colours. The genotyping of the animals was carried out by PCR-RFLP and sequ ...
... The two identified SNPs were in linkage disequilibrium in the sequenced rabbits. Therefore we selected one of them (g.39510357G>A) for the analysis of the rabbit families in which there was segregation of blue and black coat colours. The genotyping of the animals was carried out by PCR-RFLP and sequ ...
Gene Section ERG (v-ets erythroblastosis virus E26 oncogene like (avian))
... Published in Atlas Database: August 2006 Online updated version: http://AtlasGeneticsOncology.org/Genes/ERGID53ch21q22.html DOI: 10.4267/2042/38374 This work is licensed under a Creative Commons Attribution-Non-commercial-No Derivative Works 2.0 France Licence. © 2007 Atlas of Genetics and Cytogenet ...
... Published in Atlas Database: August 2006 Online updated version: http://AtlasGeneticsOncology.org/Genes/ERGID53ch21q22.html DOI: 10.4267/2042/38374 This work is licensed under a Creative Commons Attribution-Non-commercial-No Derivative Works 2.0 France Licence. © 2007 Atlas of Genetics and Cytogenet ...
Generating Marker-Free Transgenic Wheat Using Minimal Gene
... The precise elimination of selectable marker genes is highly desirable, when their function is no longer needed, because their presence raised worldwide public concerns against the release of genetically modified plants. This is the first report of simultaneous application of the minimal gene casset ...
... The precise elimination of selectable marker genes is highly desirable, when their function is no longer needed, because their presence raised worldwide public concerns against the release of genetically modified plants. This is the first report of simultaneous application of the minimal gene casset ...
Mycobacterium Strain and Type of Resistance in Pulmonary
... and both drugs, respectively. Another study in tertiary level TB center in Iran revealed that 2.6%, 0.9% and 6.3% of new cases compared to 3.6%, 3.2% and 31.7% of previously treated TB patients had INH, RIF and MDR-TB, respectively (39). In 2003 - 2004, it was reported that 2.6% of new cases and 56% ...
... and both drugs, respectively. Another study in tertiary level TB center in Iran revealed that 2.6%, 0.9% and 6.3% of new cases compared to 3.6%, 3.2% and 31.7% of previously treated TB patients had INH, RIF and MDR-TB, respectively (39). In 2003 - 2004, it was reported that 2.6% of new cases and 56% ...
Genetics of the Bombay Phenotype
... as H and the mutant as h. The genotypes of the two homozygous types and the heterobygote may be written as H/H, h/h (the Bombay phenotype) and H/h. The use of the symbol h is not meant to imply that gene h produces some alternate gene product. From the study to be presented, ...
... as H and the mutant as h. The genotypes of the two homozygous types and the heterobygote may be written as H/H, h/h (the Bombay phenotype) and H/h. The use of the symbol h is not meant to imply that gene h produces some alternate gene product. From the study to be presented, ...
投影片 1
... In the tissues activin has a strong role in cellular proliferation, and follistatin the controlled cellular proliferation and allowing it to function as an instrument of cellular differentiation In the blood, activin and follistatin are both known to be involved in the inflammatory response followin ...
... In the tissues activin has a strong role in cellular proliferation, and follistatin the controlled cellular proliferation and allowing it to function as an instrument of cellular differentiation In the blood, activin and follistatin are both known to be involved in the inflammatory response followin ...
What constitutes an `alternative TSS`? Example 1: Alternative TSS at
... What if the event involves a terminal exon? 1. Long (‘on’) exon? No – APA! ...
... What if the event involves a terminal exon? 1. Long (‘on’) exon? No – APA! ...
Genetics
... features like eye color, straight or curly hair, baldness, attached vs. free ear lobes, the ability to taste certain substances, and even whether you have dry or sticky earwax! Other genes may actually cause disease. Sickle cell anemia, muscular dystrophy, cystic fibrosis are each caused by a specif ...
... features like eye color, straight or curly hair, baldness, attached vs. free ear lobes, the ability to taste certain substances, and even whether you have dry or sticky earwax! Other genes may actually cause disease. Sickle cell anemia, muscular dystrophy, cystic fibrosis are each caused by a specif ...
Divergence with Gene Flow: Models and Data
... debate over sympatric speciation that emerged in the late twentieth century. Neither had an inkling of genes or even the rudiments of an appropriate inheritance model, and yet Wagner put his finger precisely on that factor that can prevent divergence. If Darwin’s model was to be correct, and if his p ...
... debate over sympatric speciation that emerged in the late twentieth century. Neither had an inkling of genes or even the rudiments of an appropriate inheritance model, and yet Wagner put his finger precisely on that factor that can prevent divergence. If Darwin’s model was to be correct, and if his p ...
Refine Query Set - University of Delaware
... embryogenesis. RTK pathways establish cell fates in a wide range of developmental processes. However, how the pathway effector MAPK coordinately regulates the expression of multiple target genes is not fully understood. We have previously shown that the EGFR RTK pathway causes phosphorylation and do ...
... embryogenesis. RTK pathways establish cell fates in a wide range of developmental processes. However, how the pathway effector MAPK coordinately regulates the expression of multiple target genes is not fully understood. We have previously shown that the EGFR RTK pathway causes phosphorylation and do ...
A Case Study of Leopard Appaloosa Alpacas in one
... mean, however, that both the dam and sire would need to carry the gene to produce appaloosa coloured offspring. The study of pedigrees of the leopard appaloosas in the Ambersun herd showed them to have been sired by five separate males. If the gene is so rare, it seems beyond coincidence that five d ...
... mean, however, that both the dam and sire would need to carry the gene to produce appaloosa coloured offspring. The study of pedigrees of the leopard appaloosas in the Ambersun herd showed them to have been sired by five separate males. If the gene is so rare, it seems beyond coincidence that five d ...
Article
... and tissue differentiation processes, general housekeeping chores, and seed protein accumulation at appropriate embryogenic stages; more recently, gene action has been implicated in the lapse into dormancy of embryos during their final stage of development (for review: Raghavan, 1997). This paper pr ...
... and tissue differentiation processes, general housekeeping chores, and seed protein accumulation at appropriate embryogenic stages; more recently, gene action has been implicated in the lapse into dormancy of embryos during their final stage of development (for review: Raghavan, 1997). This paper pr ...
High-resolution mapping of the leaf rust disease resistance gene Lr1
... http//apps.fao.org/). However, the production of wheat is significantly affected by different diseases. Leaf or brown rust disease caused by the fungal pathogen Puccinia recondita f. sp. tritici is the most common disease in wheat production. Epidemics of this disease can lead to severe losses of gr ...
... http//apps.fao.org/). However, the production of wheat is significantly affected by different diseases. Leaf or brown rust disease caused by the fungal pathogen Puccinia recondita f. sp. tritici is the most common disease in wheat production. Epidemics of this disease can lead to severe losses of gr ...
Biological Ontologies - Protein Information Resource
... What is Gene Ontology? GO provides controlled vocabulary to describe gene and gene product attributes in any organism – how gene products behave in a cellular context ...
... What is Gene Ontology? GO provides controlled vocabulary to describe gene and gene product attributes in any organism – how gene products behave in a cellular context ...
From QTLs for enzyme activity to candidate genes in maize
... Results and discussion Candidate genes associated with carbon metabolism in source and sink leaves In a first experiment the feasibility of the project was tested using 65 RILs. The enzyme activities (SPS and AGP) and the carbohydrate contents (sucrose, glucose and fructose) were measured in the sou ...
... Results and discussion Candidate genes associated with carbon metabolism in source and sink leaves In a first experiment the feasibility of the project was tested using 65 RILs. The enzyme activities (SPS and AGP) and the carbohydrate contents (sucrose, glucose and fructose) were measured in the sou ...
Unequal Crossing Over Locus by KIR Cutting Edge: Expansion of the
... sequencing, and segregation analysis of KIR genes in the family indicated that two known alleles of both KIR2DL4 (X97229, AF034773) and KIR3DL1/S1 (AF262969, AF022044) segregated on the c haplotype, whereas a single distinct allele of each of these loci segregated on each of the a, b, and d haplotyp ...
... sequencing, and segregation analysis of KIR genes in the family indicated that two known alleles of both KIR2DL4 (X97229, AF034773) and KIR3DL1/S1 (AF262969, AF022044) segregated on the c haplotype, whereas a single distinct allele of each of these loci segregated on each of the a, b, and d haplotyp ...
Winter 2010
... • Homozygosity (β+/β+) or compound heterozygosity (β+/β0) • These individuals have clinical symptoms that range between hose seen with β-thalassemia minor and β-thalassemia major • Laboratory findings may be similar to those in β-thalassemia trait but are generally more severe 3. Beta thalassemia ma ...
... • Homozygosity (β+/β+) or compound heterozygosity (β+/β0) • These individuals have clinical symptoms that range between hose seen with β-thalassemia minor and β-thalassemia major • Laboratory findings may be similar to those in β-thalassemia trait but are generally more severe 3. Beta thalassemia ma ...
Identification of a novel testis‐specific gene and its potential roles in
... other cell types. Most of these genes also exhibit stagespecific expression during spermatogenesis, which could be considered as spermatogenic cell type-specific since the occurrence of different spermatogenic cell types is also stage-specific during spermatogenesis. Therefore, the spermatogenic cel ...
... other cell types. Most of these genes also exhibit stagespecific expression during spermatogenesis, which could be considered as spermatogenic cell type-specific since the occurrence of different spermatogenic cell types is also stage-specific during spermatogenesis. Therefore, the spermatogenic cel ...
Genetic mapping of Theobroma cacao (Malvaceae - Funpec-RP
... mTcCIR 8, mTcCIR 12, mTcCIR 13, and mTcCIR 60) were monomorphic for both genotypes (Pa 30 and Pa 169); 20 were polymorphic. The remaining 10 primers (mTcCIR 1, mTcCIR 7, mTcCIR 11, mTcCIR 17, mTcCIR 22, mTcCIR 28, mTcCIR 33, mTcCIR 42, mTcCIR44, and mTcCIR 57) produced non-informative bands for this ...
... mTcCIR 8, mTcCIR 12, mTcCIR 13, and mTcCIR 60) were monomorphic for both genotypes (Pa 30 and Pa 169); 20 were polymorphic. The remaining 10 primers (mTcCIR 1, mTcCIR 7, mTcCIR 11, mTcCIR 17, mTcCIR 22, mTcCIR 28, mTcCIR 33, mTcCIR 42, mTcCIR44, and mTcCIR 57) produced non-informative bands for this ...
Journal of Applied Phycology
... The S. platensis recA gene has an identity of 72%, 68% and 60% when compared to the recA genes of Anabaena variabilis (Owttrim & Coleman, 1989) Synechococcus PCC 7002 (Murphy et al., 1990) and Escherichia coli (Sancar et al., 1980). Comparison of the amino acid sequences reveals an identity of 79%, ...
... The S. platensis recA gene has an identity of 72%, 68% and 60% when compared to the recA genes of Anabaena variabilis (Owttrim & Coleman, 1989) Synechococcus PCC 7002 (Murphy et al., 1990) and Escherichia coli (Sancar et al., 1980). Comparison of the amino acid sequences reveals an identity of 79%, ...
Gene therapy
Gene therapy is the therapeutic delivery of nucleic acid polymers into a patient's cells as a drug to treat disease. Gene therapy could be a way to fix a genetic problem at its source. The polymers are either expressed as proteins, interfere with protein expression, or possibly correct genetic mutations.The most common form uses DNA that encodes a functional, therapeutic gene to replace a mutated gene. The polymer molecule is packaged within a ""vector"", which carries the molecule inside cells.Gene therapy was conceptualized in 1972, by authors who urged caution before commencing human gene therapy studies. By the late 1980s the technology had already been extensively used on animals, and the first genetic modification of a living human occurred on a trial basis in May 1989 , and the first gene therapy experiment approved by the US Food and Drug Administration (FDA) occurred on September 14, 1990, when Ashanti DeSilva was treated for ADA-SCID. By January 2014, some 2,000 clinical trials had been conducted or approved.Early clinical failures led to dismissals of gene therapy. Clinical successes since 2006 regained researchers' attention, although as of 2014, it was still largely an experimental technique. These include treatment of retinal disease Leber's congenital amaurosis, X-linked SCID, ADA-SCID, adrenoleukodystrophy, chronic lymphocytic leukemia (CLL), acute lymphocytic leukemia (ALL), multiple myeloma, haemophilia and Parkinson's disease. Between 2013 and April 2014, US companies invested over $600 million in the field.The first commercial gene therapy, Gendicine, was approved in China in 2003 for the treatment of certain cancers. In 2011 Neovasculgen was registered in Russia as the first-in-class gene-therapy drug for treatment of peripheral artery disease, including critical limb ischemia.In 2012 Glybera, a treatment for a rare inherited disorder, became the first treatment to be approved for clinical use in either Europe or the United States after its endorsement by the European Commission.