MDMA (Ecstasy) - cloudfront.net
... these neurotransmitters to be released from their storage sites in neurons, resulting in increased neurotransmitter activity. Compared to the very potent stimulant, methamphetamine, MDMA causes greater serotonin release and somewhat lesser dopamine release.17 Serotonin is a neurotransmitter that pla ...
... these neurotransmitters to be released from their storage sites in neurons, resulting in increased neurotransmitter activity. Compared to the very potent stimulant, methamphetamine, MDMA causes greater serotonin release and somewhat lesser dopamine release.17 Serotonin is a neurotransmitter that pla ...
NIDA Research Report - MDMA
... and cocaine. Also, as with many other drugs of abuse, MDMA is rarely used alone. It is not uncommon for users to mix MDMA with other substances, such as alcohol and marijuana. ...
... and cocaine. Also, as with many other drugs of abuse, MDMA is rarely used alone. It is not uncommon for users to mix MDMA with other substances, such as alcohol and marijuana. ...
NIDA Research Report - MDMA
... and cocaine. Also, as with many other drugs of abuse, MDMA is rarely used alone. It is not uncommon for users to mix MDMA with other substances, such as alcohol and marijuana. ...
... and cocaine. Also, as with many other drugs of abuse, MDMA is rarely used alone. It is not uncommon for users to mix MDMA with other substances, such as alcohol and marijuana. ...
Analysis of 3, 4-Methylenedioxymethamphetamine (MDMA) and its
... Several animal studies (rat and mouse) have shown that MDMA is metabolized by N-demethylation, Oodealkylation, deamination, O-methylation,and O-conjugation to glucuronides and/or sulfates. Metabolites detected in urine are 3,4-methylenedioxyamphetamine (Figure 1, MDA), 4-hydroxy-3-methoxymethampheta ...
... Several animal studies (rat and mouse) have shown that MDMA is metabolized by N-demethylation, Oodealkylation, deamination, O-methylation,and O-conjugation to glucuronides and/or sulfates. Metabolites detected in urine are 3,4-methylenedioxyamphetamine (Figure 1, MDA), 4-hydroxy-3-methoxymethampheta ...
MDMA-Like Stimulus Effects of a-Ethyltryptamine and the cz
... to a-ethyltryptamine (a-EtT) results in a psychoactive agent with, as might be expected, reduced potency relative to aMeT. (For a comparison of the effects of tx-MeT and tx-EtT in humans, see Murphree et al. [11].) Due to the structural relationships amongst these agents, it was of interest to deter ...
... to a-ethyltryptamine (a-EtT) results in a psychoactive agent with, as might be expected, reduced potency relative to aMeT. (For a comparison of the effects of tx-MeT and tx-EtT in humans, see Murphree et al. [11].) Due to the structural relationships amongst these agents, it was of interest to deter ...
The Role of The A2A Receptor in Cell Apoptosis Caused by MDMA
... serotonergic neurons, but this is less clear with humans (3). The onset of its effect can take 20 to 60 minutes to occur, with a peak at 60 to 90 minutes following ingestion. The primary effects last for 3 to 5 hours. MDMA usually induces a relaxed, euphoric state, including emotional openness, empa ...
... serotonergic neurons, but this is less clear with humans (3). The onset of its effect can take 20 to 60 minutes to occur, with a peak at 60 to 90 minutes following ingestion. The primary effects last for 3 to 5 hours. MDMA usually induces a relaxed, euphoric state, including emotional openness, empa ...
10 Facts About MDMA - Drug Policy Alliance
... MDMA, often referred to as “ecstasy” or “molly”, is short for 3,4 methylenedioxymethamphetamine, a psychoactive drug derived from safrole oil. MDMA produces effects that resemble both stimulants and psychedelics, as well as its signature effect: a feeling of connectedness. It impacts brain function ...
... MDMA, often referred to as “ecstasy” or “molly”, is short for 3,4 methylenedioxymethamphetamine, a psychoactive drug derived from safrole oil. MDMA produces effects that resemble both stimulants and psychedelics, as well as its signature effect: a feeling of connectedness. It impacts brain function ...
Methysergide Potentiates the Hyperactivity Produced by MDMA in
... hydrochloride (provided by the National Institute on Drug Abuse) and methysergide maleate were dissolved in saline ...
... hydrochloride (provided by the National Institute on Drug Abuse) and methysergide maleate were dissolved in saline ...
(MDMA), Amphetamine, and LSD
... Correspondence to: A. C. Parrott, Department of Psychology, University of East London, London E15 4LZ, UK. ...
... Correspondence to: A. C. Parrott, Department of Psychology, University of East London, London E15 4LZ, UK. ...
Acute and Chronic Effects of 3-4 - Avicenna Journal of Neuro Psych
... especially among adolescents and young adults. According to the United Nations, in 2009 the worldwide prevalence of MDMA use ranged from 11 to 28 million individuals who were between the ages of 5 and 64 years (2). Moreover, MDMA leads to elevated mood, feeling of closeness towards others and a desi ...
... especially among adolescents and young adults. According to the United Nations, in 2009 the worldwide prevalence of MDMA use ranged from 11 to 28 million individuals who were between the ages of 5 and 64 years (2). Moreover, MDMA leads to elevated mood, feeling of closeness towards others and a desi ...
hyperthermia - Calgary Emergency Medicine
... E.g. 5 mg/kg in squirrel = 1.4 mg/kg in humans Typical recreational human doses fall within toxic doses in animals corrected for interspecies dosing ...
... E.g. 5 mg/kg in squirrel = 1.4 mg/kg in humans Typical recreational human doses fall within toxic doses in animals corrected for interspecies dosing ...
Molly: The Not So Convincing Truth of MDMA
... In the last few years, users of MDMA have also taken up the habit of “preloading” and “post-loading” before and after the ingestion of MDMA (5). Since MDMA works on a cellular level in the brain, pre and post loading are used to control the affects of MDMA through the use of vitamins and supplements ...
... In the last few years, users of MDMA have also taken up the habit of “preloading” and “post-loading” before and after the ingestion of MDMA (5). Since MDMA works on a cellular level in the brain, pre and post loading are used to control the affects of MDMA through the use of vitamins and supplements ...
Ecstasy info
... significantly more errors in PM (remembering to do something in the future); these findings persisted after controlling for other drug use and the number of strategies used to aid memory. No difference was found between representative subgroups on the Lies Scale of the Eysenck Personality Questionna ...
... significantly more errors in PM (remembering to do something in the future); these findings persisted after controlling for other drug use and the number of strategies used to aid memory. No difference was found between representative subgroups on the Lies Scale of the Eysenck Personality Questionna ...
MDMA (Ecstasy/Molly)
... 3,4-methylenedioxy-methamphetamine (MDMA) is a synthetic drug that alters mood and perception. It is chemically similar to stimulants and hallucinogens. MDMA is commonly called Ecstasy or Molly. Users typically take MDMA as a capsule or tablet. Many users take it in combination with other drugs. MDM ...
... 3,4-methylenedioxy-methamphetamine (MDMA) is a synthetic drug that alters mood and perception. It is chemically similar to stimulants and hallucinogens. MDMA is commonly called Ecstasy or Molly. Users typically take MDMA as a capsule or tablet. Many users take it in combination with other drugs. MDM ...
MDMA powder
... (shortened to "E", "X", or "XTC"), usually referring to its street form, although this term may also include the presence of possible adulterants. The UK term "Mandy" and the US term "Molly" colloquially refer to MDMA that is relatively free of adulterants. Although recently, "Molly" is no longer es ...
... (shortened to "E", "X", or "XTC"), usually referring to its street form, although this term may also include the presence of possible adulterants. The UK term "Mandy" and the US term "Molly" colloquially refer to MDMA that is relatively free of adulterants. Although recently, "Molly" is no longer es ...
mdmA - Department of Cognitive Science
... Decreased brain concentrations of serotonin and its metabolite 5-HIAA Decrease in density of SERT (serotonin re-uptake transporter) Is this down-regulation? Or have serotonergic axons been permanently lost or damaged? Down regulation suggests an active adaptation to the increase in serotonin from ec ...
... Decreased brain concentrations of serotonin and its metabolite 5-HIAA Decrease in density of SERT (serotonin re-uptake transporter) Is this down-regulation? Or have serotonergic axons been permanently lost or damaged? Down regulation suggests an active adaptation to the increase in serotonin from ec ...
NIDA for Teens Ecstasy Quiz
... C. MDMA is known as a “club drug” because teens and young adults have taken the drug at a nightclub or all-night party. ...
... C. MDMA is known as a “club drug” because teens and young adults have taken the drug at a nightclub or all-night party. ...
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... ing, and anxiety—that may occur soon after taking the drug or during the days or even weeks thereafter. ...
... ing, and anxiety—that may occur soon after taking the drug or during the days or even weeks thereafter. ...
DrugFacts MDMA 2013
... MDMA acts by increasing the activity of three neurotransmitters, serotonin, do-‐ pamine, and norepinephrine. The emo-‐ tional and pro-‐social effects of MDMA are likely caused directly or indirectly by the rele ...
... MDMA acts by increasing the activity of three neurotransmitters, serotonin, do-‐ pamine, and norepinephrine. The emo-‐ tional and pro-‐social effects of MDMA are likely caused directly or indirectly by the rele ...
RIA Reaching Others: `Molly` Who? The New Ecstasy
... Recently, organizers of a New York City music festival cancelled the last day of performances when two people died—and four more were hospitalized in critical condition—due to ingesting the club drug “Molly.” ...
... Recently, organizers of a New York City music festival cancelled the last day of performances when two people died—and four more were hospitalized in critical condition—due to ingesting the club drug “Molly.” ...
Ecstasy - UCSD Cognitive Science
... dehydration, high blood pressure, heart failure, kidney failure, arrhythmia, loss of consciousness, seizures, hyperthermia, hyponatremia (low sodium levels) ...
... dehydration, high blood pressure, heart failure, kidney failure, arrhythmia, loss of consciousness, seizures, hyperthermia, hyponatremia (low sodium levels) ...
Hallucinogens - People Server at UNCW
... and primates (see Morton, 2005 for a review) • Effects were present in primate brain 7 years after MDMA exposure Hatzidimitrious et al., 1999) ...
... and primates (see Morton, 2005 for a review) • Effects were present in primate brain 7 years after MDMA exposure Hatzidimitrious et al., 1999) ...
Ecstasy ("X") Drug Effects Information KNOW THE FACTS and DON
... MDMA is most often available in tablet form and is usually ingested orally. It is also available as a powder and is sometimes snorted and occasionally smoked, but rarely injected. Its effects last approximately four to six hours. Users of the drug say that it produces profoundly positive feelings, e ...
... MDMA is most often available in tablet form and is usually ingested orally. It is also available as a powder and is sometimes snorted and occasionally smoked, but rarely injected. Its effects last approximately four to six hours. Users of the drug say that it produces profoundly positive feelings, e ...
MOLLY- "NOT YOUR BEST FRIEND"
... the urinary route. Detection windows for MDMA in urine and oral fluid are 1-3 days and 1 day, respectively. Molly is promoted as a highly purified version of MDMA, although that claim has never been verified due to the illicit nature of MDMA. As with all other illicit drugs, there were reports that ...
... the urinary route. Detection windows for MDMA in urine and oral fluid are 1-3 days and 1 day, respectively. Molly is promoted as a highly purified version of MDMA, although that claim has never been verified due to the illicit nature of MDMA. As with all other illicit drugs, there were reports that ...
MDMA
MDMA (contracted from 3,4-methylenedioxy-methamphetamine) is a psychoactive drug of the substituted methylenedioxyphenethylamine and substituted amphetamine classes of drugs that is consumed primarily for its euphoric and empathogenic effects. Pharmacologically, MDMA acts as a serotonin-norepinephrine-dopamine releasing agent and reuptake inhibitor.MDMA has become widely known as ""ecstasy"" (shortened to ""E"", ""X"", or ""XTC""), usually referring to its tablet form, although this term may also include the presence of possible adulterants. The UK term ""Mandy"" and the US term ""Molly"" colloquially refer to MDMA in a crystalline powder form that is relatively free of adulterants. ""Molly"" can sometimes also refer to the related drugs methylone, MDPV, mephedrone or any other of the pharmacological group of compounds commonly known as bath salts.Possession of MDMA is illegal in most countries. Some limited exceptions exist for scientific and medical research. In 2013 between 9 and 28 million people used ecstasy recreationally (0.2% to 0.6% of the global population between the ages of 15 and 65). This was broadly similar to the number for cocaine, substituted amphetamines, and opioids, but far fewer than the number of cannabis users. It is taken in a variety of contexts and is commonly associated with dance parties (or ""raves"") and electronic dance music.MDMA may have health benefits in certain mental disorders, but has potential adverse effects, such as neurotoxicity and cognitive impairment. More research is needed in order to determine if its potential usefulness in posttraumatic stress disorder (PTSD) treatment outweighs the risk of persistent neuropsychological harm to a patient.