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Introduction
Introduction

... • gather idea of important terms (H-bonds, overlap, ..) • try to find some function which often works • do not stick to real physics Will my drug dissolve in water or oil (lipid) ? (important) • sounds like chemistry • usually approached by machine learning • number of atoms, types of atoms, … http: ...
Shetti, a simple tool to parse, manipulate and search large datasets
Shetti, a simple tool to parse, manipulate and search large datasets

Characterizing the Secreted Proteome of Mycobacterium
Characterizing the Secreted Proteome of Mycobacterium

... The goal of this research was to characterize proteins secreted specifically by the ESX-1 secretion apparatus into the culture supernatant. The analytical challenge lies in the fact that there are many other proteins present in the culture supernatant. In addition, a major problem is differentiating ...
Biophysical Society On
Biophysical Society On

... nitrogen atoms. One of these nitrogens already has a proton on it, but the other one has an available position that can take up an extra proton and form a positively charged histidine group with a pKa of about 6. Aspartic acid and glutamic acid differ only in the number of methylene (-CH2 -) groups ...
Determination and Quantification of Molecular Interactions in Protein
Determination and Quantification of Molecular Interactions in Protein

... orientated. And third, the formation of a three dimensional network is stabilized by new interactions and bonds. A wet process based on dispersion or solubilization of proteins, and a dry process based on the thermoplastic processing of proteins are used to make protein-based films [4]. Protein-base ...
supporting information file s1
supporting information file s1

... individual models can vary significantly, therefore, we extensively evaluated the model quality using different software which estimate the local quality of the predicted structure (S4). Graphical plots of Anolea mean force potential which performs energy calculations on a protein chain and is used ...
Protein Sequence and Structural Similarity
Protein Sequence and Structural Similarity

... (Proteomics) Which proteins are being produced in Nucleus which cells/tissues when? Which modified forms are present? ...
Detection of Cellular Response to an in vitro Challenge with
Detection of Cellular Response to an in vitro Challenge with

... was set to 100 ms. Dynamic exclusion is turned on using a peak width of 60 s. ...
Chem 301 Biological Chemistry I Laboratory Lab 7: Protein
Chem 301 Biological Chemistry I Laboratory Lab 7: Protein

... and transmissible spongiform encephalopathies, like Creutzfeldt-Jacob and mad cow disease. NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY You have learned about Nuclear magnetic resonance (NMR) with regard to organic molecule identification and chemical structure determination. But NMR is a powerful tool f ...
Detailed proteome analysis of growing cells of the planctomycete
Detailed proteome analysis of growing cells of the planctomycete

... Rhodopirellula baltica SH1T, which was isolated from the water column of the Kieler Bight, a bay in the southwestern Baltic Sea, is a marine aerobic, heterotrophic representative of the ubiquitous bacterial phylum Planctomycetes. We analyzed the R. baltica proteome by applying different preanalytica ...
Journal of Bacteriology
Journal of Bacteriology

... Nitrogen fixation of Azospirillum spp., as free-living organisms and in association with the roots of a variety of nonleguminous plants, has been studied intensively since rediscovery of Azospirillum spp. as N2 fixers (for reviews, see references 1, 7, 22, 32). The organisms can grow and fix N2 unde ...
Chapter 27 - Extras Springer
Chapter 27 - Extras Springer

...  Contains different compounds than Chinese ginseng  Previous studies were not conducted well and are unreliable  The few well-designed studies have failed to show an ergogenic benefit (Winterstein & Storrs, 2001). ...
Chapter 2 part 3
Chapter 2 part 3

... • Proteins have important functions in cells. – Proteins form the antibodies of the immune system that defend the body from disease. – Proteins such as insulin are hormones that regulate cellular function. – Contractile proteins such as actin and myosin allow parts of cells to move and muscles to co ...
Full-Text
Full-Text

... Prions (proteinaceous infectious particles, PrPTSE (TSE = transmissible spongiform encephalopathy)) are the causative agents of fatal neurodegenerative diseases as bovine spongiform encephalopathy (BSE) in cattle, scrapie in sheep, chronic wasting disease (CWD) in cervids and Creutzfeldt-Jakob disea ...
The Plant Cell
The Plant Cell

... 1). It consists of three putative SH3 binding PRDs and a C-terminal DnaJ domain (Figure 8B). Sequence alignment suggested that the DnaJ domain was similar only to those from the auxilin protein family (Figure 8C). Significantly, the plant DnaJ domain contained the HPD motif that was known to be cruc ...
Sec14p-like proteins regulate phosphoinositide homoeostasis and
Sec14p-like proteins regulate phosphoinositide homoeostasis and

... by the increased capacity of sec14-1ts cells to secrete invertase [12]. It is also interesting that the SFH protein most related to Sec14p by homology is not a functional Sec14p on the basis of several important criteria. Yeast cells overexpressing Sfh1p have at best a very low grade Sec14p-independ ...
Leukaemia Section inv(8)(p11q13) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section inv(8)(p11q13) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... in acute myeloid leukemia. Blood. 1998 May 1;91(9):3127-33 ...
BBSRC 24/B11662 "Protein processing and electron transfer in
BBSRC 24/B11662 "Protein processing and electron transfer in

... is observed in the active site of the enzyme as a potential substrate. This is accompanied by the presence of an additional water in C383S compared to wild-type, that interacts with the OH of Tyr405 and therefore suggests an altered pattern of H-bonds that may be responsible for the enhanced substr ...
Contents
Contents

High Density Cobalt Agarose
High Density Cobalt Agarose

... from bulk affinity resins: • Shake the bottle manually to obtain a homogenous suspension of the affinity resin. Place a funnel in the column head and slowly pour the suspension down the walls of the column. Please note: Add the suspension slowly to avoid the formation of bubbles. The suspension may al ...
The Genome Sequence of the SARS
The Genome Sequence of the SARS

... regions spanning approximately residues 34-56, 77-99, and 103-125. The most likely model from these analyses is that the C-terminus and a large 149 amino - terminal domain would be located inside the viral or cellular membrane. The C-terminal (interior) region of the protein may encode a protein dom ...
Finding of a novel fungal immunomodulatory protein coding
Finding of a novel fungal immunomodulatory protein coding

... The search for transcripts (contigs) potentially related to immunomodulatory proteins allowed for the identification of 24 initial candidate sequences showing significant alignments to nonFIP immunomodulatory proteins (data not shown). A further BLAST search against GenBank non-redundant nucleotide ...
sorghum protein - Simply Sorghum
sorghum protein - Simply Sorghum

... bran is a rich source of condensed tannins, also known as proanthocyanidins, specifically containing epicatechin and catechin. Black sorghum bran contains anthocyanins, including 3-deoxyanthocyanins (apigeninidin) and luteolinidin7. The high levels of 3-deoxyanthocyanins are relatively rare in natur ...
Statistical analysis of DNA microarray data
Statistical analysis of DNA microarray data

... The term threading was first coined by Jones, Taylor and Thornton in 1992, and originally referred specifically to the use of a full 3-D structure atomic representation of the protein template in fold recognition. Today, the terms threading and fold recognition are frequently (though somewhat incorr ...
Koi Food facts and Nutrition myths Duncan Griffiths
Koi Food facts and Nutrition myths Duncan Griffiths

... out the back of the koi without ever gaining inclusion into the koi’s body. The carp has to break protein down into short chain amino acids instead of long chain molecules. At this point it’s still a struggle to absorb them to where they are needed for cell generation so these are further broken dow ...
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Interactome



In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.
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