The HSSP database of protein structure–sequence
... the derived secondary structure and solvent accessibility calculated from the coordinates using DSSP (2), (ii) aligned sequences of a few or tens or hundreds of sequences from the SWISS-PROT database (3) deemed structurally homologous to this protein (iii) at each position in the multiple sequence a ...
... the derived secondary structure and solvent accessibility calculated from the coordinates using DSSP (2), (ii) aligned sequences of a few or tens or hundreds of sequences from the SWISS-PROT database (3) deemed structurally homologous to this protein (iii) at each position in the multiple sequence a ...
Proteins include a diversity of structures
... DNA provides directions for its own replication DNA directs synthesis of messenger RNA (mRNA) and, through mRNA, controls protein synthesis This process is called gene expression ...
... DNA provides directions for its own replication DNA directs synthesis of messenger RNA (mRNA) and, through mRNA, controls protein synthesis This process is called gene expression ...
Chapter 1
... • Second most common secondary structure appears similar to folds of fabric • All of the carbonyl O and amide H are involved in the H bonds with the chain nearly completely extended • Two possible orientations – Parallel if the N-termini are head-to-head – Antiparallel if the N-terminus of one chain ...
... • Second most common secondary structure appears similar to folds of fabric • All of the carbonyl O and amide H are involved in the H bonds with the chain nearly completely extended • Two possible orientations – Parallel if the N-termini are head-to-head – Antiparallel if the N-terminus of one chain ...
PREDICTION OF DELETERIOUS NONSYNONYMOUS SINGLE NUCLEOTIDE POLYMORPHISMS (nsSNPs) OF GALC GENE BY COMPUTATIONAL METHOD
... Single Nucleotide Polymorphisms (SNPs) are the most abundant sequence variations encountered in a genome and play a major role in understanding of the genetic basis of many complex human diseases. The genetics of human phenotype variation could be understood by knowing the funct ...
... Single Nucleotide Polymorphisms (SNPs) are the most abundant sequence variations encountered in a genome and play a major role in understanding of the genetic basis of many complex human diseases. The genetics of human phenotype variation could be understood by knowing the funct ...
Chapter 6 Protein: Amino Acids The Chemist`s View of Proteins
... Protein denaturization-heat, acid disturb their stability and cause them to denature; they uncoil and lose their shape and function Protein Digestion in the GI Tract Protein Digestion Protein Synthesis Human body contains an estimated 30,000 different kinds of proteins. Each protein is determined ba ...
... Protein denaturization-heat, acid disturb their stability and cause them to denature; they uncoil and lose their shape and function Protein Digestion in the GI Tract Protein Digestion Protein Synthesis Human body contains an estimated 30,000 different kinds of proteins. Each protein is determined ba ...
Protein and Amino Acids
... potentially available to contribute to the amino acid pool, whereas those that pass to the ________ are not. Does quality of protein generally dictate where ...
... potentially available to contribute to the amino acid pool, whereas those that pass to the ________ are not. Does quality of protein generally dictate where ...
Биологическая химия
... of certain enzymes, called proteinases (proteases, peptidases). This yields a mixture of peptides and amino acids. • Study of the products of partial and complete hydrolysis of peptides and proteins play is important for the understanding of their structure. ...
... of certain enzymes, called proteinases (proteases, peptidases). This yields a mixture of peptides and amino acids. • Study of the products of partial and complete hydrolysis of peptides and proteins play is important for the understanding of their structure. ...
Pseudoatom-driven solvent accessibility refinement (PaDSAR) Method
... Patching and solvating the full-length models with pseudoatoms Two categories of pseudoatoms are introduced in the system, i.e., spin-label pseudoatoms and environment pseudoatoms [1], as summarized in Table 1. The spin-label pseudoatoms are further classified into five different types, denoted EP1, ...
... Patching and solvating the full-length models with pseudoatoms Two categories of pseudoatoms are introduced in the system, i.e., spin-label pseudoatoms and environment pseudoatoms [1], as summarized in Table 1. The spin-label pseudoatoms are further classified into five different types, denoted EP1, ...
Proteins
... The measurement of globulins based on their tryptophan content has never come into common use because of the ease and simplicity of the dye-binding methods for albumin. ...
... The measurement of globulins based on their tryptophan content has never come into common use because of the ease and simplicity of the dye-binding methods for albumin. ...
Chapter 3: Enzymes: Structure and Function
... dipole-dipole, dispersion forces and covalent bonds) which all help repeatedly catalyze the reaction (catch and release). It is usually proposed that the transition state complex is stabilized, lowering the activation energy which accelerates the reaction rate. Rather than the old 'lock and key' mod ...
... dipole-dipole, dispersion forces and covalent bonds) which all help repeatedly catalyze the reaction (catch and release). It is usually proposed that the transition state complex is stabilized, lowering the activation energy which accelerates the reaction rate. Rather than the old 'lock and key' mod ...
Amino Acids Interactions
... A single point mutation in an invariant protein region has dire consequences when these changes occur frequently in a population =polymorphism Currently about 33% of loci in human genome appear to be Polymorphic sickle cell point mutation is a stable polymorphism in population > heterozygote provide ...
... A single point mutation in an invariant protein region has dire consequences when these changes occur frequently in a population =polymorphism Currently about 33% of loci in human genome appear to be Polymorphic sickle cell point mutation is a stable polymorphism in population > heterozygote provide ...
Prolyl Isomerases –Old Proteins as New Therapeutic Targets
... “classical” synthetic molecules typically made by medicinal chemists. Unfortunately, there exists nowadays a certain reluctance amongst medicinal chemists to work with natural products. This reluctance was adopted by decision makers and medicinal chemistry programmes based on natural products have, ...
... “classical” synthetic molecules typically made by medicinal chemists. Unfortunately, there exists nowadays a certain reluctance amongst medicinal chemists to work with natural products. This reluctance was adopted by decision makers and medicinal chemistry programmes based on natural products have, ...
13073_2014_97_MOESM5_ESM
... was optimized to generate maximum recall. Figure 1 shows the output sentences generated by following a machine learning approach. ...
... was optimized to generate maximum recall. Figure 1 shows the output sentences generated by following a machine learning approach. ...
SWISS-PROT + TrEMBL
... SWISS-PROT excels in annotation, exhibits very little redundancy and is thoroughly integrated with other databses. The extensive annotation and exhaustive to reduce redundancy mean that entries can take time before they are made available, but when they are, they are a complete and thorough resource ...
... SWISS-PROT excels in annotation, exhibits very little redundancy and is thoroughly integrated with other databses. The extensive annotation and exhaustive to reduce redundancy mean that entries can take time before they are made available, but when they are, they are a complete and thorough resource ...
Characterizing Protein/Ligand Binding by DSC
... binding specific molecules such as other proteins, cofactors, prosthetic groups or drugs. Efforts to understand the mechanisms controlling selective binding were initially prompted by the realization that recognition and binding are universal features of all biochemical processes. These efforts have ...
... binding specific molecules such as other proteins, cofactors, prosthetic groups or drugs. Efforts to understand the mechanisms controlling selective binding were initially prompted by the realization that recognition and binding are universal features of all biochemical processes. These efforts have ...
Protein Functional Annotation - Institute for Genome Sciences
... –! they may or may not share the same function! –! two proteins are either homologs of each other or they are not. A protein can not be more, or less, homologous to one protein than to another.! ...
... –! they may or may not share the same function! –! two proteins are either homologs of each other or they are not. A protein can not be more, or less, homologous to one protein than to another.! ...
Protein Synthesis - Beaver Local High School
... Anticodon- a region of tRNA consisting of three bases complementary to the codon of mRNA Amino acids floating freely in the cytosol are transported to the ribosomes by tRNA molecules ...
... Anticodon- a region of tRNA consisting of three bases complementary to the codon of mRNA Amino acids floating freely in the cytosol are transported to the ribosomes by tRNA molecules ...
Pa I I, hl. L. Blasticidin-S: on... Cycloheximide has been used widely as ...
... in light microscopic studies. 4. Not only spindle fiben (which attach to chromatin regions), but also a tightly compressed longitudinal bundle of filaments (which stretcher the late telophase daughter nuclei ) is seen. This filament bundle may be similar to the “Zentralrtrong” described by Girbordt. ...
... in light microscopic studies. 4. Not only spindle fiben (which attach to chromatin regions), but also a tightly compressed longitudinal bundle of filaments (which stretcher the late telophase daughter nuclei ) is seen. This filament bundle may be similar to the “Zentralrtrong” described by Girbordt. ...
Slide
... – Large side chains take up more space than small ones – Hydrophobic side chains want to be near one another – Hydrophilic side chains form hydrogen bonds to one another and to water molecules – Negatively charged (acidic) side chains want to be near positively charged (basic) side chains ...
... – Large side chains take up more space than small ones – Hydrophobic side chains want to be near one another – Hydrophilic side chains form hydrogen bonds to one another and to water molecules – Negatively charged (acidic) side chains want to be near positively charged (basic) side chains ...
bbr052online 329..336 - Oxford Academic
... In recent years, numerous biocomputational tools have been designed to extract functional and evolutionary information from multiple sequence alignments (MSAs) of proteins and genes. Most biologists working actively on the characterization of proteins from a single or family perspective use the MSA ...
... In recent years, numerous biocomputational tools have been designed to extract functional and evolutionary information from multiple sequence alignments (MSAs) of proteins and genes. Most biologists working actively on the characterization of proteins from a single or family perspective use the MSA ...
SALT BRIDGE D526- FUNCTIONS AS A HINGE THAT CONTROLS
... interactions at the interface between both subdomains and within the lid subdomain have been disrupted. Our data show that ionic contacts, most likely forming an electrically charged network, between the Nterminal region of helix B and an inner loop of the β-sandwich are involved in maintaining the ...
... interactions at the interface between both subdomains and within the lid subdomain have been disrupted. Our data show that ionic contacts, most likely forming an electrically charged network, between the Nterminal region of helix B and an inner loop of the β-sandwich are involved in maintaining the ...
Interactome
In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.