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Profile Documents Logout
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Immunity
Immunity

... antibodies of a great range of structures both in their binding regions as well as in their effector regions.  Even if one were to isolate a single antibody-secreting cell, and place it in culture, it would die out after a few generations because of the limited growth potential of all normal somati ...
SDRC_Spotlight_-_Spring_2009 5 24 09
SDRC_Spotlight_-_Spring_2009 5 24 09

... Despite the challenging funding climate, the Department of Dermatology maintains an outstanding portfolio of external research support. Department scientists currently hold three NIH R01 grants and two VA Merit Review awards. In addition, Drs. Laura Timares and Mohammad Athar recently competed succe ...
PEDIATRIC ORAL PATHOLOGY
PEDIATRIC ORAL PATHOLOGY

treatment
treatment

... Test utility depends on how good the treatment is RR and p-values good for hypothesis testing/statistics ARR and NNT (and NNH) better for interpreting clinical importance ARR = risk difference  NNT = 1/NNT ...
division - IRIS - Lake Land College
division - IRIS - Lake Land College

... •Convert all measures to the same system and same unit of measure within the system before calculating drug dosage. •Calculate drug dosages correctly •Calculate intravenous flow rate using one of the given formulas. ...
Dr. CHETHANA. SG
Dr. CHETHANA. SG

... in diameter with a poorly defined lateral margin which appears and darkens on light exposed skin sites during periods of UV exposure. They are common in children and individuals of all ages who are red or fair haired and fair skinned. 9 Becker’s nevus or pigmented hairy epidermal nevus was first rep ...
A i rway Cl ear ance
A i rway Cl ear ance

... Corp, Auckland, New Zealand). Although these devices have been shown to improve patients' comfort (Chanques G et al., 2009). Pharmacologically Active Aerosols Inhaled therapy has several well-recognized advantages over other drug delivery routes. The drug is delivered directly to its targeted site o ...
Phase I - II clinical trial of conventional cytotoxic chemotherapy
Phase I - II clinical trial of conventional cytotoxic chemotherapy

... Anti-cancer effects of vitamin C: In millimolar concentrations, vitamin C in the form of ascorbic acid (AA) is cytotoxic to many cancer cells but innocuous to normal ones. Cancercytotoxic concentrations can be achieved in experimental animals and humans after parenteral injection. Vitamin C has anti ...
Poisonings by Cardiovascular Drugs in Yekaterinburg, Russia
Poisonings by Cardiovascular Drugs in Yekaterinburg, Russia

... admission and ICU care was needed for 45.7% of patients. Men significantly outnumbered women in veratrine poisoning (P < 0.001) while women significantly outnumbered men in clonidine (P < 0.001), drotaverine (P < 0.001), CCB (P < 0.001) and beta blocker (P = 0.012) poisoning. The most frequent compl ...
Knowledge
Knowledge

...  Drug interactions – the increase or decrease of drug action, or emergence of a new nontypical effect of a medication, caused by the simultaneous administration of another drug.  Drug implementation – in case of clinical pharmacology it means mainly clinical trial of drugs with the aim of studying ...
Guidelines for the conduct of clinical trials for spinal cord injury as
Guidelines for the conduct of clinical trials for spinal cord injury as

... tasked with reviewing the methodology for clinical trials for spinal cord injury (SCI), and making recommendations on the conduct of future trials. This is the third of four papers. It examines inclusion and exclusion criteria that can influence the design and analysis of clinical trials in SCI, toge ...
Sickle Cell Disease
Sickle Cell Disease

... side effect of chronic transfusion is iron overload. There are medications that need to be taken regularly to help lower the iron in the body. Pain medications – pain medications such as acetaminophen (Tylenol), ibuprofen (Advil, Motrin) and sometimes narcotics (e.g. morphine, codeine, hydrocodone, ...
Histoplasmosis with Addisonian Crisis: Call for Bird Control
Histoplasmosis with Addisonian Crisis: Call for Bird Control

Fish Oils and Kidney Disorders
Fish Oils and Kidney Disorders

... of overall health and studies have shown that abnormalities in the relative concentrations of essential fatty acids (EFAs) are associated with many common diseases such as diabetes and rheumatoid arthritis. The EFA profile of cell membranes is usually measured in the phospholipid phase of blood plas ...
Understanding Clinical Trial Design
Understanding Clinical Trial Design

... About the Tutorial The purpose of this tutorial is to provide a strategy that research advocates can use to constructively contribute to planning clinical trials. It should also assist them to critically assess already designed trials they may be asked to critique (e.g., in grant proposals), as well ...
Aug 5
Aug 5

... Temperatures will relatively cool down this week. There is 80 percent chance of thundershowers this evening. Therefore the risk of leaf disease symptoms either appearing or increasing in your crops is moderate. If significant rain occurs and resulted in extended period of leaf wetness, then the risk ...
Journal of IMAB Annual Proceeding (Scientific Papers) 2010
Journal of IMAB Annual Proceeding (Scientific Papers) 2010

... guidelines, and MICs were determined using Vitek 2 system. Results. In the period of 2002-2005, 17 enterococci were collected and in the period 2006-2009 that number was 62. The identified species were: E. faecalis (41; 51,90%) , E. faecium (27; 34,18%) and E. durans (2; 2,53%), while 9 (11,39%) Ent ...
An Update on Celiac Disease Histopathology and the Road Ahead
An Update on Celiac Disease Histopathology and the Road Ahead

... integration of clinical, genetic, and histopathologic criteria as the individuals lack serum autoantibodies.63 These individuals are more likely to have either normal villous architecture with increased IEL counts or mild degrees of villous atrophy, and they likely lack a humoral response to the aut ...
Sudden cardiac death and antipsychotics Part 2: Monitoring and
Sudden cardiac death and antipsychotics Part 2: Monitoring and

... gain, which may have an additive adverse effect. On the basis of risk of sudden cardiac death and risk of QTc prolongation we suggest considering antipsychotics in two categories – higher and lower risk. Of most concern is the use of large cumulative doses of antipsychotics that are sometimes given ...
documents 1 - Tainted Blood
documents 1 - Tainted Blood

... because between them they account for more than 95% of all patients having serious congenital coagulation defects which require treatment by coagulation factor replacement. In a report on the first 3 years of this survey in 1974 (Biggs, 1974), the amount of factor VIII used to treat haemophilic pati ...
Medicare Criteria: Requirements for Rebate
Medicare Criteria: Requirements for Rebate

... abnormal Liver Function Tests (LFT), in which case 3 tests per episode will be covered by Medicare. Some conditions apply to combinations of tests. Antenatal Hepatitis Testing Only HBs Ag and Hep C Ab can be performed alongside other antenatal serology, unless the patient has clinical notes indicati ...
Phase IIa study of single-agent MOR208 in patients
Phase IIa study of single-agent MOR208 in patients

... refractory NHL who had received at least one prior therapy containing the CD20 antibody, rituximab: – Primary endpoint: objective response rate. ...
2009 - School of Medicine - Case Western Reserve University
2009 - School of Medicine - Case Western Reserve University

... Infection with the human immunodeficiency virus-1 (HIV-1) predisposes patients to Kaposi’s sarcoma (KS), a vascular tumor caused by the Kaposi’s sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8). Independent KSHV infection confers far less risk of developing KS versus ...
www.bhbt.co.uk
www.bhbt.co.uk

Induction and maintenance therapy in ANCA
Induction and maintenance therapy in ANCA

... disease, (31 patients in total) which may have contaminated the results. Although a power calculation was performed, the study did not have sufficient numbers to show a difference of the magnitude proposed. The results showed no significant difference in toxicity, either as infectious complications ...
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Multiple sclerosis research

Treatments under investigation for multiple sclerosis may improve function, curtail attacks, or limit the progression of the underlying disease. Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclerosis. There are also trials involving the combination of drugs that are already in use for multiple sclerosis. Finally, there are also many basic investigations that try to understand better the disease and in the future may help to find new treatments.
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