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Cutaneous Lupus Erythematosus
Cutaneous Lupus Erythematosus

... which are directly pathogenic, including dsDNA, and Ro/SSA antibodies.  Lupus patients have reduced clearance of immune complexes by the reticuloendothelial system  Most of the tissue injury is due to B-cells due to immune complex and complement mediated damage through  1. Direct cell death  2. ...
mri evaluation of patients with shoulder pain at three imaging
mri evaluation of patients with shoulder pain at three imaging

... The total number of patients imaged was 70. Among them, 12(16.7%) were imaged at Plaza Imaging All consenting patients of all age groups with shoulder Solutions, 13(18.0%) were imaged at KNH and pain and referred for MR Imaging during the period 47(65.3%) were imaged at Nairobi Hospital. Two male be ...
inflammatory bowel disease monitor
inflammatory bowel disease monitor

... C. Capsule endoscopy has been shown to detect fewer intestinal lesions than small-bowel follow through D. A and B E. A and C 3. Indications for capsule endoscopy include: A. To diagnose Crohn’s disease in patients who are suspected of having the disease in the clinic, but have normal radiological te ...
Contents
Contents

... formulation and delivery, as a medicine, and can ensure its safe and effective use by patients. Pharmacists also have a deep understanding of pharmacology and therapeutics, the physicochemical properties of drugs and excipients, biopharmacy and pharmacokinetics, side effects, contraindications and dru ...
Hypersensitivity to intravenous iron: classification, terminology
Hypersensitivity to intravenous iron: classification, terminology

... Among the alternative classifications of HSR mechanisms, Descotes proposed 3 categories: immunoglobulin-mediated, cell-mediated and pseudoallergic (Descotes et al., 2001). Pichler labelled his 5 categories with Greek letters: type a reactions involve cytokine release, b-type reactions are immune rea ...
Addition of sildenafil to bosentan monotherapy in pulmonary arterial
Addition of sildenafil to bosentan monotherapy in pulmonary arterial

... disease was defined based upon a combination of pulmonary function tests and chest radiography as previously described elsewhere [12]. The diagnosis of scleroderma was based upon American College of Rheumatology criteria [18]. Bosentan therapy was prescribed at recommended doses according to the pac ...
PDF full-Text - Journal of Investigational Allergology and Clinical
PDF full-Text - Journal of Investigational Allergology and Clinical

... was prescribed. Her skin symptoms persisted despite the discontinuation of penicillin. On examination, she had a maculopapular rash that was more prominent on the trunk, generalized desquamation, bilateral enlarged cervical lymphadenopathy, and edema of the eyes and feet. The liver was palpable 3 cm ...
Public Summary Document (Word 142 KB)
Public Summary Document (Word 142 KB)

... cut-off values between 4.4% and 5.3% for ‘proximal’ oesophageal pH monitoring. The sensitivity and specificity in these studies varied from 67% to 100% and from 66% to 100%, respectively. No studies compared the accuracy of catheter-free and catheter-based against the reference standard of clinical ...
pdf doc - Institute for Molecular Medicine
pdf doc - Institute for Molecular Medicine

... inexpensive for the patient – approximately one-fourth or less the cost of IV treatments. Calcium disodium EDTA chelation supports broad-spectrum heavy metal removal and is approved by the United States Food and Drug Administration. Rectal suppository chelation has been proven effective in pre-clini ...
NON-SMALL CELL LUNG CANCER STAGE IV Effective Date: November, 2013
NON-SMALL CELL LUNG CANCER STAGE IV Effective Date: November, 2013

... members of the Alberta Provincial Thoracic Tumour Team do not currently recommended the combination of three chemotherapeutic agents for the first-line treatment of advanced NSCLC (recommendation #3). Non-platinum-based chemotherapy. A phase III RCT by Flotten et al in 2012 examined the efficacy of ...
Foundation of Knowledge for the General Dentist for INBDE
Foundation of Knowledge for the General Dentist for INBDE

... • formation and removal of free radicals from cells and conditions under which tissue injury occurs due to lack of perfusion • susceptibility of different cell types (cardiomyocytes, neurons) to the effects of anoxic injury caused by vascular compromise FK6-2: Apply knowledge of the vascular and leu ...
The Neuropsychiatry of Hematopoietic Stem Cell Transplantation
The Neuropsychiatry of Hematopoietic Stem Cell Transplantation

... oligodendrocytes and then enter glial cells via receptor-mediated clathrin-dependent endocytosis (Pho et al. 2000). MRI appearance in T2-weighted images is generally seen as asymmetric nonenhancing bilateral bright lesions in the white and sometimes grey matter and brain stem, which may become confl ...
Non-Small Cell Lung Cancer Stage IV
Non-Small Cell Lung Cancer Stage IV

... members of the Alberta Provincial Thoracic Tumour Team do not currently recommended the combination of three chemotherapeutic agents for the first-line treatment of advanced NSCLC (recommendation #3). Non-platinum-based chemotherapy. A phase III RCT by Flotten et al in 2012 examined the efficacy of ...
Full Text
Full Text

... demyelination, with neurodegeneration (71). In MS, activated T-cells, specific for self-antigens, such as myelin, migrate into CNS and result in axonal demyelination (96). First line therapy for patients with MS is immunosuppression/immunomodulation therapy that is generally employed with success (9 ...
Heart Failure:
Heart Failure:

... All phosphate binders are similarly effective. Calcium-based products are often used as first line due to their ease of administration, and limited risk of toxicity. However, non-calcium based products are a safer alternative in patients who experience hypercalcemic symptoms or have an elevated calc ...
A guide to Multiple System Atrophy for: Speech and Language
A guide to Multiple System Atrophy for: Speech and Language

34-Year-Old Woman With Abdominal Pain and Blood
34-Year-Old Woman With Abdominal Pain and Blood

... d. Surgical intervention does not have a role in the treatment of chronic ischemic colitis. e. Long-term anticoagulation is indicated in the presence of abnormal coagulation studies. Most cases of ischemic colitis are of a mild form (transient ischemic colitis) that resolves with supportive measures ...
Course 19
Course 19

Data Sheet
Data Sheet

... close supervision of high-risk patients should accompany therapy. Use in Pregnancy (Category C) Studies in animals by oral route have shown reproductive toxicity (dose related embryo foetotoxicity: increased resorptions and dead foetuses). Increased incidence of malformations was observed in mice bu ...
病案討論 -Systemic Lupus Erythematosus
病案討論 -Systemic Lupus Erythematosus

... Assessment: 2.This patients with dangerous proliferative forms of glomerular damage and proteinuria (>500 mg per 24 h) therefore, aggressive immunosuppression is indicated (usually systemic glucocorticoids plus a cytotoxic drug) but proteinuria is less likely to improve on lupus nephritis immunosupp ...
Evaluation of Vitamin D Status in Newly Diagnosed Pemphigus Vulgaris Patients
Evaluation of Vitamin D Status in Newly Diagnosed Pemphigus Vulgaris Patients

... the importance of the potential relationship between vitamin D and PV, there are a few published studies on this subject and all of them showed the same results as ours. However, the exact underlying mechanisms are not well recognized yet. The strength of the present study is to include only newly d ...
Sunvepra - Bristol-Myers Squibb Canada
Sunvepra - Bristol-Myers Squibb Canada

The New Golden Era for Radioimmunotherapy
The New Golden Era for Radioimmunotherapy

... development of HAMAs. In 1997, rituximab was the first monoclonal antibody to receive approval by the US Food and Drug Administration (FDA).9 During the next several years, the development of RIT agents for B-cell non-Hodgkin lymphoma continued, which led to the FDA approval of 90Y ibritumomab tiuxe ...
136th Annual Meeting of the American Neurological Association
136th Annual Meeting of the American Neurological Association

... It is likely, however, that many additional factors modulate the likelihood of subsequent clinical decline. Longitudinal studies are ongoing to determine if these amyloid-positive older individuals are indeed in the preclinical stages of AD, and to elucidate the endophenotype that best predicts thos ...
Medicare National Coverage Determinations Manual Coverage Determinations
Medicare National Coverage Determinations Manual Coverage Determinations

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Multiple sclerosis research

Treatments under investigation for multiple sclerosis may improve function, curtail attacks, or limit the progression of the underlying disease. Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclerosis. There are also trials involving the combination of drugs that are already in use for multiple sclerosis. Finally, there are also many basic investigations that try to understand better the disease and in the future may help to find new treatments.
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