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Introduction - World Health Organization
Introduction - World Health Organization

... The purpose of the monographs was clearly explained in the introduction to volume 1, and it is unnecessary to repeat it here. However, it is important to emphasize that the word “monograph”, as appears in the title, is used as a technical term only. These monographs are not intended to be official ph ...
Medicare Coverage Policies May 2013 update
Medicare Coverage Policies May 2013 update

... failure) among patients with acute coronary syndrome (myocardial infarction with or without T-wave elevation and unstable angina) has been established. However, the assessment of BNP level has not been shown to alter patient management. The BNP is not sufficiently sensitive to either preclude or nec ...
Tumor necrosis factor antagonist mechanisms of action: A
Tumor necrosis factor antagonist mechanisms of action: A

... and adalimumab are monoclonal antibodies (mAbs) that specifically bind TNF; and etanercept is a TNF-receptor Fc-fusion protein that binds TNF and lymphotoxin (LT) family members. In addition, 2 other TNF antagonists in development — certolizumab pegol, refered to as certolizumab hereafter, and golim ...
Sudden Death Associated with Hypersensitivity Myocarditis Induced
Sudden Death Associated with Hypersensitivity Myocarditis Induced

... of our knowledge, no previous studies claiming that they could be responsible for eosinophylic myocarditis23-25. The study of Ronaldson et al. also reported that secondary drugs used during clozapine treatment were not associated with myocarditis risk except for sodium valproate25. When all these fa ...
Review - Antimicrobe.org
Review - Antimicrobe.org

... the introduction of quinolones, the cure rate has increased to 90%, with few adverse effects reported. Ciprofloxacin (750 mg orally twice per day) seems to be the antibiotic of choice, based on clinical experience and comparative in-vitro susceptibility studies; however, comparative trials have not ...
Academy of Applied Hypnosis
Academy of Applied Hypnosis

... Svensson, 2011; Tahiri, Mottillo, Joseph, Pilote, & Eisenberg, 2012) demonstrates encouraging outcomes and calls for further high quality research. As hypnotherapy training is only available in the vocational sector and research methods are taught in the higher education sector, research is primaril ...
AusPAR: Eplerenone  - Therapeutic Goods Administration
AusPAR: Eplerenone - Therapeutic Goods Administration

... Evaluator’s conclusions on clinical efficacy for the proposed additional indication To reduce the risk of cardiovascular mortality and morbidity in adult patients with NYHA Class II heart failure and left ventricular systolic dysfunction in addition to standard optimal therapy. Overall, the study de ...
CIPROFLOXACIN - ciprofloxacin   injection, solution, concentrate For Intravenous Infusion
CIPROFLOXACIN - ciprofloxacin injection, solution, concentrate For Intravenous Infusion

... microorganisms resistant to these classes of drugs may be susceptible to ciprofloxacin and other quinolones. There is no known crossresistance between ciprofloxacin and other classes of antimicrobials. In vitro resistance to ciprofloxacin develops slowly by multiple step mutations. Ciprofloxacin is ...
overview of antimicrobial therapy - Home
overview of antimicrobial therapy - Home

Human leptospirosis: guidance for diagnosis, surveillance and control
Human leptospirosis: guidance for diagnosis, surveillance and control

... Leptospirosis is a worldwide public health problem. In humid tropical and subtropical areas, where most developing countries are found, it is a greater problem than in those with a temperate climate. The magnitude of the problem in tropical and subtropical regions can be largely attributed to climat ...
Abstract presented at American College of Clinical
Abstract presented at American College of Clinical

... bosentan and warfarin. METHODS: Patients in a pharmacist-managed anticoagulation clinic were directly observed for potential drug interactions at each clinic visit. Three clinic patients were initiated on bosentan while already taking warfarin. Along with other clinically significant information, ne ...
Allergic bronchopulmonary aspergillosis: review of - LIFE
Allergic bronchopulmonary aspergillosis: review of - LIFE

... useful test in both diagnosis and follow-up of ABPA. A normal serum IgE (in the absence of systemic glucocorticoid therapy) generally excludes active ABPA as the cause of patient’s current symptoms. There is no consensus on the cut-off value of IgE level that should be used for diagnosis of ABPA, an ...
The reliability, validity and sensitivity to
The reliability, validity and sensitivity to

INSTITUTE FOR CLINICAL AND ECONOMIC REVIEW
INSTITUTE FOR CLINICAL AND ECONOMIC REVIEW

... waves. The test allows for the evaluation of muscle function in different areas of the heart to identify weak or damaged areas of the muscle. This is done through a comparison of images at rest and under cardiac stress induced by exercise or pharmacologic means. Clinically, the test is simple to per ...
Reiki-Review Of A Biofield Therapy History, Theory
Reiki-Review Of A Biofield Therapy History, Theory

... fields (EMFs), invisible lines of electrical force or currents. Although the existence of EMFs has been demonstrated, therapeutic use of these fields is unique to complementary modalities such as magnet therapy.4 Biofield therapies, including Reiki, are generally accepted as low-risk interventions. ...
The use of docetaxel, paclitaxel, gemcitabine and vinorelbine
The use of docetaxel, paclitaxel, gemcitabine and vinorelbine

... and the USA, than in the UK. Only about 5% of people with lung cancer survive for 5 years, and nearly all of these are cured by surgery after fortuitously early diagnosis. At present, only a small proportion of patients (probably about 5%) with non-small cell lung cancer are being given chemotherapy ...
Phage therapy: awakening a sleeping giant
Phage therapy: awakening a sleeping giant

... Current antibiotic therapies are the result of decades of iterative implementations coupled to experimental and clinical studies to deliver highly effective treatment dependent on antibiotic type and setting. One major breakthrough was the use of synthetic approaches to expand the natural narrow spe ...
Minerva Neurosciences, Inc. (Form: 10-K, Received
Minerva Neurosciences, Inc. (Form: 10-K, Received

... We believe MIN-101 reflects scientifically supported and innovative mechanisms of action to potentially address the unmet needs of this patient population. We plan to initially seek approval of MIN-101 as a first line monotherapy. We will also study its use as an adjunctive therapy. We believe that ...
a PDF of this supplement
a PDF of this supplement

... good level 1 evidence. It’s probably a failure on all of our parts that there isn’t good level 1 evidence that allows you to compare such a good modality of treatment with other standard modalities out there. But if I had to do every case with level 1 evidence, I would only get half my cases done, r ...
68th Annual Meeting, Miami Beach, Fla., March 5
68th Annual Meeting, Miami Beach, Fla., March 5

... is associated with significant side effects, such as mucocutaneous involvement, dyslipidemia, and increased liver enzymes. Because liver enzymes (SGOT, SGPT, etc) were found elevated during isotretinoin treatment, which is the sign of liver dysfunction, the responsible enzyme for homocysteine metabo ...
Product Information: Trastuzumab - Therapeutic Goods Administration
Product Information: Trastuzumab - Therapeutic Goods Administration

... were equivalent in women treated with pre-operative (neoadjuvant) chemotherapy and women treated with post-operative (adjuvant) chemotherapy. Pre-operative (neoadjuvant) chemotherapy increased breast conservation rates, but at the cost of increased loco-regional recurrence rates. However, loco-regio ...
Therapeutic Area Data Standards User Guide for Influenza
Therapeutic Area Data Standards User Guide for Influenza

... This Therapeutic Area Data Standards User Guide for Influenza (TAUG--Influenza) is a provisional standard, which means that it has been published for initial use, but is dependent upon completion of other standards and thus may involve risk of upcoming change. This TAUG-Influenza was developed under ...
abstract book - XVII International Symposium on Progress in Clinical
abstract book - XVII International Symposium on Progress in Clinical

The Selection and Use of Essential Medicines
The Selection and Use of Essential Medicines

... agents, including daclatasvir, dasabuvir, ledipasvir + sofosbuvir, ombitasvir  + paritaprevir  + ritonavir, simeprevir, and sofosbuvir, for the treatment of hepatitis C. The recommendations for inclusions were based on the comparative efficacy, increased tolerability, and potential public health imp ...
management of migraine - Choose your language | Know Pain
management of migraine - Choose your language | Know Pain

... Treatment of Migraine • Effective in abortive therapy of mild to severe migraine • Improvement in pain-free periods, reductions in pain intensity and migraine-associated symptoms • Combination with caffeine or other abortive agents – including triptans – may offer additional benefit in some patients ...
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Multiple sclerosis research

Treatments under investigation for multiple sclerosis may improve function, curtail attacks, or limit the progression of the underlying disease. Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclerosis. There are also trials involving the combination of drugs that are already in use for multiple sclerosis. Finally, there are also many basic investigations that try to understand better the disease and in the future may help to find new treatments.
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