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Drug-induced immune thrombocytopenia
Drug-induced immune thrombocytopenia

... Epidemiologic studies performed in the US and Europe suggest that about 10 persons per million are affected by drug-induced immune thrombocytopenia (DITP) annually [3], but the incidence could be higher in elderly and hospitalized persons, who are more likely to be exposed to medications. A study pe ...
Assessment Schedule – 2005 Human Biology: Describe how
Assessment Schedule – 2005 Human Biology: Describe how

... pathogens / acid conditions in vagina not suitable for pathogens ! pathogens can’t reproduce. ...
Pervasive Healthcare as a Scientific Discipline
Pervasive Healthcare as a Scientific Discipline

clinical protocol for the use of injected local anaesthetics in
clinical protocol for the use of injected local anaesthetics in

... kidneys, they should be used with caution and at a lower maximum dose in patients with liver and renal disease. For patients with cardiac disease (such as ischemic heart disease, arrhythmia’s, angina) caution should be taken when giving any local anaesthetic, especially those containing adrenaline. ...
GRANULOMATOUS HEPATITIS
GRANULOMATOUS HEPATITIS

Tumour Necrosis Factor-α (TNF-α) antagonists and Tuberculosis
Tumour Necrosis Factor-α (TNF-α) antagonists and Tuberculosis

... There is concern that new groups of drugs called TNF-α antagonists, which are being used effectively to modify the immune system response in the treatment of a number of immune-mediated diseases, may be associated with a risk of developing TB infection and clinically active TB disease. This briefing ...
Aeris Therapeutics
Aeris Therapeutics

... The auction process is being managed by xxxxxx xxxxxx an intangible asset disposition company engaged by the assignee of the creditors of Aeris Therapeutics. In conversations with Hilco, it was stated the transaction value should be in the “low seven figures.” The target close date is February 28th, ...
T A J M
T A J M

Approach to diagnosis of metabolic diseases
Approach to diagnosis of metabolic diseases

... The definition of an inborn error of metabolism is arbitrary. Scriver et al. [5] include several hundred diseases with definite biochemical genetic bases. McKusick’s catalog [6] contains several thousand diseases and disease states whose genetic abnormalities are described or assumed. Scriver et al. ...
STRATEGIC INFORMATION SYSTEMS PLAN
STRATEGIC INFORMATION SYSTEMS PLAN

... focusing on outcomes and decreasing costs Selected antimicrobials  Bug-drug mismatches  Inappropriate durations of therapy  De-escalation opportunities ...
Patch testing and cross sensitivity in adverse
Patch testing and cross sensitivity in adverse

... sodium valproate frequently makes selection of an alternative agent difficult[3]. The focus has shifted in recent years on the utility of drug patch test in cutaneous adverse drug reactions for ease and positive results can be useful to confirm drug imputability established on clinical grounds. More ...
The Immune System
The Immune System

... infected body cells = decompressor are needed to see this picture. “bomber cells” ...
Continuous versus intermittent therapy for moderate-to
Continuous versus intermittent therapy for moderate-to

... arthritis reported a safety profile that is comparable to NSAIDs; this same group did report 111 patients who developed laboratory abnormalities, but only 27 of these cases were clinically significant, where nine patients had significant increases in AST and 11 had significant decreases in albumin ( ...
Use of probe-based confocal laser endomicroscopy (pCLE) in
Use of probe-based confocal laser endomicroscopy (pCLE) in

... With the implementation of physician payment in the United States (US) and ongoing coverage efforts, standardisation of training modalities and subsequent practice in a ‘routine care’ setting is essential. In 2012, in the US, specific reimbursement (current procedural terminology (CPT)) codes were cre ...
A Guide to Clinical Differential Diagnosis of Oral Mucosal Lesions
A Guide to Clinical Differential Diagnosis of Oral Mucosal Lesions

... without treatment. They are usually not painful early in their development, and the growth rate varies from weeks to years. Benign and Malignant Tumors If a soft tissue enlargement appears to be a tumor, the clinician must next determine if the enlargement is benign or malignant. Benign tumors are t ...
FELINE CALICIVIRUS - Clinician`s Brief
FELINE CALICIVIRUS - Clinician`s Brief

... • Upper respiratory signs such as conjunctivitis and/or rhinitis, often as a coinfection with other feline upper respiratory pathogens; less commonly, bronchointerstitial pneumonia3 • Oral and/or lingual ulcerations; vesicular lesions on the nasal philtrum or footpads1 • Chronic gingivitis/ ...
1 SPhSD 2014
1 SPhSD 2014

... 8. Patient/public advocacy, zero risk culture, ethics 9. Demographics, longevity, chronic diseases 10. Globalization, emerging markets (BRIC countries) 11. Financial system In this lecture attention will be paid to the expected impact of a selected number of these drivers. The continuing fast advanc ...
32 Personalized PD-L1 blockade breaks through triple
32 Personalized PD-L1 blockade breaks through triple

... for collecting cancer DNA for mutation testing, but retrieving tumor DNA from a patient’s urine is least invasive of all. In an early phase of clinical investigation, researchers assessed the feasibility of using urine to collect cell-free tumor DNA to detect mutations in 34 patients with advanced n ...
Vancomycin dosing and monitoring - Salford Royal NHS Foundation
Vancomycin dosing and monitoring - Salford Royal NHS Foundation

... resistance emerges and spreads. It will also minimise the many side effects associated with antibiotic prescribing, such as Clostridium difficile infection. It should be borne in mind that antibiotics are not needed for simple coughs and colds. In some clinical situations, where infection is one of ...
2
2

... basis and the decision of whether to attempt to eradicate Pseudomonas was at the discretion of the treating physician. Out of 66 P. aeruginosa culture-positive patients, 34 (25.8%) did not receive any treatment while 32 (24.2%) were treated either with oral ciprofloxacin or appropriate intravenous a ...
12 Post-Cardiac Surgery Fungal Endocarditis
12 Post-Cardiac Surgery Fungal Endocarditis

... antigen (66, 67), and β-D-glucan (68-71) have been detected in some studies. However, there are a few reports on the use of such antigens in patients with FE. Antibody assays can be helpful for some species of fungi which are not the normal flora but there are problems with both specificity and sens ...
Longitudinal assessment in COPD patients: multidimensional variability and outcomes
Longitudinal assessment in COPD patients: multidimensional variability and outcomes

... In the studies evaluating lung function, the annual decline has been expressed as a mean value for groups or as a change calculated from individual FEV1 slopes [3]. However, many authors, including FLETCHER and PETO [6], noticed irregular patterns with wide swings in FEV1 that are not expressed in t ...
What is ovarian cancer?
What is ovarian cancer?

... There is still a good deal of uncertainty around PRR’s viability in most of its prospective markets. Early clinical trials, although positive, give no real enough indication of a product’s true viability and full foresight on future market conditions is difficult to obtain. In its favour, PRR’s base ...
Thyroid Cases
Thyroid Cases

... B. Radionucleotide uptake scan C. Thyroid ultrasound D. Observation E. Initiation of prednisone Sick-euthyroid syndrome can occur in any acute, severe illness. TSH/T4/T3 abnormalities are thought to result from release of cytokines in response to severe stress. The most common hormone pattern is low ...
Autoinflammatory diseases and the inflammasome: mechanisms of
Autoinflammatory diseases and the inflammasome: mechanisms of

... pronounced in FMF as it was in cryopyrin-associated periodic syndrome (CAPS) mediated by a gain-of-function mutation of NLRP3. Of great interest would be the effect of therapy that targets IL-1 for preventing AA amyloidosis8). However, long-term studies are needed to determine whether or not progres ...
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Multiple sclerosis research

Treatments under investigation for multiple sclerosis may improve function, curtail attacks, or limit the progression of the underlying disease. Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclerosis. There are also trials involving the combination of drugs that are already in use for multiple sclerosis. Finally, there are also many basic investigations that try to understand better the disease and in the future may help to find new treatments.
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