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Guidelines for the Management of Vitiligo The European Dermatology Forum Consensus
Guidelines for the Management of Vitiligo The European Dermatology Forum Consensus

... Only a few randomized trials have been published,[12,18–21] showing beneficial results mainly in the head and neck region, both in adults and children. Ultraviolet (UV) radiation exposure during TIM treatment may play a synergistic role,[22] but long-term safety studies are not available. Controvers ...
MAP training: combining meditation and aerobic exercise reduces
MAP training: combining meditation and aerobic exercise reduces

... only reduce ruminative thoughts, but would also ameliorate deficits in cognitive control processes. To assess this change, event-related brain potentials (ERPs) were recorded during a cognitive control task that involves conflict monitoring and inhibitory control (that is, a modified Eriksen flanker tas ...
71 PSORIASIS
71 PSORIASIS

... In the 1950s, Dr. John Ingram developed the “Ingram regimen,” combining UVB radiation and topically applied anthralin to the plagues. By the late 1950s, following the discovery of cortisone a decade earlier, topical corticosteroid formulations started to be developed and applied to affected lesions ...
WAO Guideline for the Management of Hereditary Angioedema
WAO Guideline for the Management of Hereditary Angioedema

... United Kingdom; 11Allergy and Asthma Specialists, Dallas, TX; 12Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité-Universitätsmedizin Berlin, Berlin, Germany; 13Department of Medicine, University of Alberta, Edmonton, Canada; 14Division of Allergy, Dept. of Pediatrics, Nippon ...
Avastin versus Lucentis: Why It Matters
Avastin versus Lucentis: Why It Matters

... What about Patients Who Demand Lucentis? Genentech’s media blitz has encouraged many people to request Lucentis. We tell patients that Avastin appears roughly equal in safety and effectiveness. One reason we prefer Avastin is that it may require less frequent injections, which would help reduce the ...
Managing dyspnea in patients with advanced chronic obstructive
Managing dyspnea in patients with advanced chronic obstructive

... Group. Managing dyspnea in patients with advanced chronic obstructive pulmonary disease: A Canadian Thoracic Society clinical practice guideline. Can Respir J 2011;18(2):xxx-xxx. Dyspnea is a cardinal symptom of chronic obstructive pulmonary disease (COPD), and its severity and magnitude increases a ...
Study - Tea Tree Wonders
Study - Tea Tree Wonders

... that warts present for less than one year will usually regress within two months if the wartspecific IgGb antibodies develop (Cobb 1990). This suggests that the presence of these antibodies prevent infection and help resolution to occur. However, permanent protection is not guaranteed, as individual ...
scientificprogram
scientificprogram

... neck tumours. Despite the current belief that inflammatory mediators play a pivotal role in the development of mucositis, there remains a lack of effective treatment for this debilitating side effect. The microcirculatory changes which accompany this process have not previously been examined. Orthog ...
A review of the use of combination therapies for the treatment of
A review of the use of combination therapies for the treatment of

... Clinical studies have assessed the efficacy and safety of combination medications for acne. These studies demonstrate significantly greater and faster results with the combination therapy than with the single agents alone. Combinations of topical antibiotics plus topical benzoyl peroxide, topical re ...
CaseCATs
CaseCATs

Recognising and managing antidepressant discontinuation symptoms
Recognising and managing antidepressant discontinuation symptoms

... Box 2  Examples of the misdiagnosis of anti­depressant discontinuation symptoms 1  Misdiagnosis as adverse effect of new medication Discontinuation symptoms that follow anti­depressant switching may be incorrectly diagnosed as sideeffects of the new anti­depressant (Haddad & Qureshi, 2000), which ma ...
The Red Face - American Academy of Dermatology
The Red Face - American Academy of Dermatology

... years of redness and scaling on his forehead, eyebrows, and central face. He does not complain of itching but is embarrassed by his appearance. It has not gotten better with moisturizers. It does not worsen with heat, exercise, hot foods or drinks, or alcohol.  PMH: no major illnesses or hospitaliz ...
The Frontal Sinus and Nasal Polyps
The Frontal Sinus and Nasal Polyps

... Prior to surgical intervention, a trial of topical steroid drops (not sprays) along with oral prednisone or injection of triamcinolone (40 mg/ml) into the polyps may reduce polyp size and symptoms [3]. Topical steroid drops, which can be ophthalmic or nasal drops, placed in ether a head-back (Mygind ...
Full Prescribing Information
Full Prescribing Information

... A syndrome consisting of acute myopia associated with secondary angle closure glaucoma has been reported in patients treated with topiramate, a component of Qsymia. Symptoms include acute onset of decreased visual acuity and/or ocular pain. Ophthalmologic findings can include myopia, anterior chambe ...
Community-Acquired Pneumonia - New England Journal of Medicine
Community-Acquired Pneumonia - New England Journal of Medicine

... not cough, produce sputum, or have an elevated white-cell count, and about 30% (including a greater proportion of elderly patients) are afebrile at admission.3,5,28-30 New lung infiltrates may be difficult to identify in patients with chronic lung disease, in obese patients, and in those for whom on ...
Research in EMDR
Research in EMDR

... on phantom breast pain. 13 women who underwent single or double mastectomy due to cancer. Pretest/post-test design, data were collected two weeks before and after the treatment, during follow-up at 3 months and again at 6 month ...
High prevalence of abnormal gastrointestinal permeability in
High prevalence of abnormal gastrointestinal permeability in

... that was designed and conducted in part as a learner research project (Internal Medicine Residency Project), without external funding. As such, within this section our discussion touches upon not only our study results and their implications, but also includes a synopsis of the “lessons learned” wit ...
ACC/AHA Expert Consensus Document
ACC/AHA Expert Consensus Document

... Consensus Document In July 1998, responding to inquiries from both concerned physicians and the press, ACC president Spencer King asked the ACC Technology and Practice Executive Committee (TPEC) to supervise the writing of a press release, summary statement and Expert Consensus Document on sildenafi ...
IBD Treatment
IBD Treatment

... In this monograph, we present a set of candidate quality indicators for Crohn’s disease and ulcerative colitis, along with a synthesis of the available evidence supporting a link between the indicator and an outcome of interest. We developed potential quality indicators from two sources: Review of e ...
- Journal of Vascular and Interventional Radiology
- Journal of Vascular and Interventional Radiology

... The draft document is critically reviewed by the Standards of Practice Committee members in either a telephone conference call or face-to-face meeting. The revised draft is then sent to the SIR membership for further input/criticism during a 30-day comment period. These comments are discussed by the ...
Rhinosinusitis and Asthma
Rhinosinusitis and Asthma

... An important contribution to explaining the mechanisms linking sinusitis and asthma comes from a study by Bucca et al,44 who investigated the relationship between extrathoracic airway hyperresponsiveness (EAHR) and bronchial hyperresponsiveness (BHR) in adult patients with chronic sinusitis during e ...
Hyperuricemia and Gout: A review
Hyperuricemia and Gout: A review

... evidenced by information from the Rochester project. Some of the risk factors for the development of gout include: increased ethanol intake, high dietary purine consumption, obesity and the use of certain drugs, such as diuretics. Another important risk factor for the development of gout is hyperuri ...
preventive therapy for migraine headache
preventive therapy for migraine headache

... patients with comorbid bipolar disorder or seizure disorders.10 Patients should be aware that topiramate may produce mild cognitive impairment or fatigue, which are usually transitory.11 Other adverse effects reported in more than 10% of patients with migraine headache in placebo-controlled clinical ...
A Control Model to Evaluate Pharmacotherapy for Allergic Rhinitis in
A Control Model to Evaluate Pharmacotherapy for Allergic Rhinitis in

... Treatment with an INS alone reduced outcomes related to asthma risk as measured by lung function tests and asthma symptom scores.30-32 A study30 of schoolchildren with moderate to severe PAR and no history of asthma found that approximately 25% had abnormal lung function as evidenced by a forced exp ...
Endogenous Candida endophthalmitis
Endogenous Candida endophthalmitis

... an abscess in choroid invading the retina and with vitreous cells. detection of candidemia. An initial negapatients with endogenous fungal endophthalmitis. The authors tive review should be followed by another at 2 weeks. In a proattributed these results to several factors, including culture spectiv ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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