Use of Corticosteroids in General Practice
... immunosuppressive effects. Corticosteroids, often just called “steroids”, greatly improve symptoms and provoke impressive results in number of conditions. However, there are also side effects associated with their use. It is therefore important that these drugs are used for evidence-based indication ...
... immunosuppressive effects. Corticosteroids, often just called “steroids”, greatly improve symptoms and provoke impressive results in number of conditions. However, there are also side effects associated with their use. It is therefore important that these drugs are used for evidence-based indication ...
60 - Glucocorticoid Therapy
... Apart from the steroid configuration, biologic characteristics of glucocorticoids also depend on whether they are in free form (as alcohol) or are chemically bound (as ester or salt). In their free form, glucocorticoids are virtually insoluble in water, so they can be used in tablets but not in pare ...
... Apart from the steroid configuration, biologic characteristics of glucocorticoids also depend on whether they are in free form (as alcohol) or are chemically bound (as ester or salt). In their free form, glucocorticoids are virtually insoluble in water, so they can be used in tablets but not in pare ...
Major Causes of Morbidity and Mortality in SLE
... Anatomy of the glomerulus, consisting of a tuft of capillary loops fed by the afferent arteriole. The tuft is held together by the mesangium. The enlarged capillary loop shows the components of the glomerular filtration barrier. The barrier is formed by the glycocalyx, fenestrated endothelial ...
... Anatomy of the glomerulus, consisting of a tuft of capillary loops fed by the afferent arteriole. The tuft is held together by the mesangium. The enlarged capillary loop shows the components of the glomerular filtration barrier. The barrier is formed by the glycocalyx, fenestrated endothelial ...
Multiple sclerosis– related spasticity
... problems prevent me from doing many of my daily activities ...
... problems prevent me from doing many of my daily activities ...
T-DM1 for treating HER2-positive, unresectable locally advanced or
... critiqued the manufacturer’s economic evaluation. Emma Simpson critiqued the clinical effectiveness methods and evidence. Rebecca Harvey and John Stevens critiqued the statistical analyses included in the manufacturer’s submission. Helen Buckley Woods commented on the searches included in the manufa ...
... critiqued the manufacturer’s economic evaluation. Emma Simpson critiqued the clinical effectiveness methods and evidence. Rebecca Harvey and John Stevens critiqued the statistical analyses included in the manufacturer’s submission. Helen Buckley Woods commented on the searches included in the manufa ...
The IDSA Lyme disease Guidelines - Infectious Diseases Society of
... Macrolide antibiotics are not recommended as first-line therapy for early Lyme disease, because those macrolides that have been compared with other antimicrobials in clinical trials have been found to be less effective (E-I). When used, they should be reserved for patients who are intolerant of, or ...
... Macrolide antibiotics are not recommended as first-line therapy for early Lyme disease, because those macrolides that have been compared with other antimicrobials in clinical trials have been found to be less effective (E-I). When used, they should be reserved for patients who are intolerant of, or ...
Interstitial Cystitis/ Bladder Pain Syndrome
... of the Pelvic Pain disorders (MAPP project) in the United States. Current research is looking at chronic pain and central sensitisation. In summary, there are numerous different theories and much research has been carried out, but no real answers have so far been found. No-one yet knows what causes ...
... of the Pelvic Pain disorders (MAPP project) in the United States. Current research is looking at chronic pain and central sensitisation. In summary, there are numerous different theories and much research has been carried out, but no real answers have so far been found. No-one yet knows what causes ...
A Case of Isolated Middle Cerebral Artery Stenosis with Hemichorea
... Isolated middle cerebral artery (MCA) stenosis in young patients with no other medical condition may be a unique pathologic entity with a benign long-term course. Generally, moyamoya disease shows a progression of stenosis from internal cerebral artery (ICA) to other intracranial vessel. A 26-year-o ...
... Isolated middle cerebral artery (MCA) stenosis in young patients with no other medical condition may be a unique pathologic entity with a benign long-term course. Generally, moyamoya disease shows a progression of stenosis from internal cerebral artery (ICA) to other intracranial vessel. A 26-year-o ...
Manuka honey vs. hydrogel – a prospective, open label, multicentre
... groups could not be shown. However, they are clinically significant in that a greater percentage of slough was removed by MH than by the HT. Placing the primary outcome results in the perspective with other studies is challenging because of study differences in inclusion criteria and duration of tre ...
... groups could not be shown. However, they are clinically significant in that a greater percentage of slough was removed by MH than by the HT. Placing the primary outcome results in the perspective with other studies is challenging because of study differences in inclusion criteria and duration of tre ...
Second consensus statement on the diagnosis of multiple
... minutes of standing from a previous 3-minute interval in the recumbent position. This orthostatic decline is usually accompanied by a compensatory increase in heart rate that is inadequately low for the level of blood pressure decline. We note that this is a more pronounced decrease of blood pressur ...
... minutes of standing from a previous 3-minute interval in the recumbent position. This orthostatic decline is usually accompanied by a compensatory increase in heart rate that is inadequately low for the level of blood pressure decline. We note that this is a more pronounced decrease of blood pressur ...
International guidelines for management of severe
... of pulmonary artery catheters in ALI/ARDS (1A); to decrease days of mechanical ventilation and ICU length of stay, a conservative fluid strategy for patients with established ALI/ARDS who are not in shock (1C); protocols for weaning and sedation/analgesia (1B); using either intermittent bolus sedati ...
... of pulmonary artery catheters in ALI/ARDS (1A); to decrease days of mechanical ventilation and ICU length of stay, a conservative fluid strategy for patients with established ALI/ARDS who are not in shock (1C); protocols for weaning and sedation/analgesia (1B); using either intermittent bolus sedati ...
' LACHMANCONSULTANTSERVICES,INC. Westbury,lVP 11590
... bronchodilators in such patients. In controlled clinical trials, metoprolol tartrate, administered two ar four umes daily, has been shown to be an effective antianginal agent, reducing the nuxnber of angina attacks and increasing exercise tolerance. The dosage used in these studies ranged from 100 m ...
... bronchodilators in such patients. In controlled clinical trials, metoprolol tartrate, administered two ar four umes daily, has been shown to be an effective antianginal agent, reducing the nuxnber of angina attacks and increasing exercise tolerance. The dosage used in these studies ranged from 100 m ...
wheat germ supplement reduces cyst and trophozoite
... Abstract. The protozoan parasite Giardia lamblia is a major cause of waterborne enteric disease worldwide. Lectins are proteins that bind to carbohydrate (sugar) moieties. Potential targets for lectins are found on the surface of most single-celled organisms. Modest concentrations of wheat germ aggl ...
... Abstract. The protozoan parasite Giardia lamblia is a major cause of waterborne enteric disease worldwide. Lectins are proteins that bind to carbohydrate (sugar) moieties. Potential targets for lectins are found on the surface of most single-celled organisms. Modest concentrations of wheat germ aggl ...
Endoscopic Cyclophotocoagulation (ECP) in the
... is a gradual upward trend in both IOP and glaucoma medications between 1 and 2 years (Tables 2 and 3). The success rate remains the same, however, as the upward trend is below the threshold definition for failure. In addition, the number of subjects retained at these later time points is smaller. Nev ...
... is a gradual upward trend in both IOP and glaucoma medications between 1 and 2 years (Tables 2 and 3). The success rate remains the same, however, as the upward trend is below the threshold definition for failure. In addition, the number of subjects retained at these later time points is smaller. Nev ...
The Clinical Assessment, Treatment, and
... Macrolide antibiotics are not recommended as first-line therapy for early Lyme disease, because those macrolides that have been compared with other antimicrobials in clinical trials have been found to be less effective (E-I). When used, they should be reserved for patients who are intolerant of, or ...
... Macrolide antibiotics are not recommended as first-line therapy for early Lyme disease, because those macrolides that have been compared with other antimicrobials in clinical trials have been found to be less effective (E-I). When used, they should be reserved for patients who are intolerant of, or ...
Treatment Challenges of Group A Beta
... core of most of the excised tonsils that harbored BLPB.30 Antibiotics that are effective against GABHS and are also resistant to the enzyme β-lactamase achieve higher success rates in eradication of acute and recurrent GABHS PT. These antibiotics included cephalosporins, clindamycin, lincomycin, mac ...
... core of most of the excised tonsils that harbored BLPB.30 Antibiotics that are effective against GABHS and are also resistant to the enzyme β-lactamase achieve higher success rates in eradication of acute and recurrent GABHS PT. These antibiotics included cephalosporins, clindamycin, lincomycin, mac ...
Guidelines for the management of chronic asthma in adolescents
... not always result in detectable signs. 3. Lung function in asthma Spirometric lung function tests, including measurement of peak expiratory flow, are useful in the diagnosis, assessment of severity and management (monitoring) of asthma. It may be abnormal even when symptoms and signs are absent. It ...
... not always result in detectable signs. 3. Lung function in asthma Spirometric lung function tests, including measurement of peak expiratory flow, are useful in the diagnosis, assessment of severity and management (monitoring) of asthma. It may be abnormal even when symptoms and signs are absent. It ...
PDF - Bentham Open
... this conclusion [8] and note that oral lesions can be seen in isolation from any other disease activity [11]. There has been the suggestion that anti-Smith antibodies hold an association with oral ulcers [5] but thus far other studies have not found a firm connection between the lesions and the pres ...
... this conclusion [8] and note that oral lesions can be seen in isolation from any other disease activity [11]. There has been the suggestion that anti-Smith antibodies hold an association with oral ulcers [5] but thus far other studies have not found a firm connection between the lesions and the pres ...
data sheet
... mortality compared to placebo in a meta-analysis of 17 controlled trials of atypical antipsychotic drugs, including RISPERDAL. In placebo controlled trials with oral RISPERDAL in this population, the incidence of mortality was 4.0% (40/1009) for RISPERDAL treated patients compared to 3.1% (22/712) f ...
... mortality compared to placebo in a meta-analysis of 17 controlled trials of atypical antipsychotic drugs, including RISPERDAL. In placebo controlled trials with oral RISPERDAL in this population, the incidence of mortality was 4.0% (40/1009) for RISPERDAL treated patients compared to 3.1% (22/712) f ...
Product Information: Crizotinib - Therapeutic Goods Administration
... subjects, 63% and 22% of the administered dose was recovered in faeces and urine, respectively. Unchanged crizotinib represented approximately 53% and 2.3% of the administered dose in faeces and urine, respectively. The mean apparent clearance (CL/F) of crizotinib was lower at steady state (60 L/hr) ...
... subjects, 63% and 22% of the administered dose was recovered in faeces and urine, respectively. Unchanged crizotinib represented approximately 53% and 2.3% of the administered dose in faeces and urine, respectively. The mean apparent clearance (CL/F) of crizotinib was lower at steady state (60 L/hr) ...
Протокол
... Alcoholism, asplenism, sickle cell disease and multiple myeloma predispose patients to developing pneumococcal meningitis. The infection may occur at any age, but over 50% of the cases are less than one or over fifty years of age. The two sexes are about equally involved. The clinical symptoms, phy ...
... Alcoholism, asplenism, sickle cell disease and multiple myeloma predispose patients to developing pneumococcal meningitis. The infection may occur at any age, but over 50% of the cases are less than one or over fifty years of age. The two sexes are about equally involved. The clinical symptoms, phy ...
Dilated cardiomyopathy (DCM) and myocarditis: Classification
... most common type of myocarditis in Western countries and most cases are documented or presumed to have viral origin. In order to develop uniform, and reproducible morphologic criteria for the pathologic diagnosis of myocarditis, a panel of cardiac pathologists developed a classification of the disea ...
... most common type of myocarditis in Western countries and most cases are documented or presumed to have viral origin. In order to develop uniform, and reproducible morphologic criteria for the pathologic diagnosis of myocarditis, a panel of cardiac pathologists developed a classification of the disea ...
apo Best Practice Guidelines 2013 draft
... More than 50% of Parkinsonian patients experience fluctuations in motor response after five years of levodopa (L-dopa) treatment or combined therapy (Lees AJ, 1986). The most common side effect of L-dopa therapy is 'end of dose deterioration', ‘ON-OFF’ phenomena and peak dose or biphasic dyskinesias ...
... More than 50% of Parkinsonian patients experience fluctuations in motor response after five years of levodopa (L-dopa) treatment or combined therapy (Lees AJ, 1986). The most common side effect of L-dopa therapy is 'end of dose deterioration', ‘ON-OFF’ phenomena and peak dose or biphasic dyskinesias ...
III. History of Medicare Coverage for FDG-PET
... Although the risk of developing AD increases with age, AD and dementia symptoms are not a part of normal aging. In the absence of disease, the human brain often can function well into the tenth decade of life and beyond. Use of research criteria in clinical studies of aging and cognitive impairment ...
... Although the risk of developing AD increases with age, AD and dementia symptoms are not a part of normal aging. In the absence of disease, the human brain often can function well into the tenth decade of life and beyond. Use of research criteria in clinical studies of aging and cognitive impairment ...
Management of multiple sclerosis
Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.