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Cluster Headache: Diagnosis and Treatment Rashmi Halker, M.D., Bert Vargas, M.D.,
Cluster Headache: Diagnosis and Treatment Rashmi Halker, M.D., Bert Vargas, M.D.,

... placebo-controlled, double-blind study, which compared 20 mg intranasal sumatriptan to placebo.8 One-hundred eighteen patients were enrolled and 154 cluster attacks were treated: 77 attacks with sumatriptan and 77 with placebo. At 30 minutes, 57% of attacks treated with sumatriptan responded and 47% ...
Management for the Children with Otitis Media with Effusion in the
Management for the Children with Otitis Media with Effusion in the

... Objectives. Recently, new evidence-based recommendations have been introduced for diagnosing and managing otitis media with effusion (OME) in children. However, there are some difficulties to follow the general guidelines in the tertiary hospitals. The purpose is to evaluate the efficiency of antibi ...
methadone hydrochloride oral concentrate USP
methadone hydrochloride oral concentrate USP

... amenorrhea, or infertility. The causal role of opioids in the clinical syndrome of hypogonadism is unknown because the various medical, physical, lifestyle, and psychological stressors that may influence gonadal hormone levels have not been adequately controlled for in studies conducted to date. Eff ...
Patient Monitoring Checklist - OPDIVO® (nivolumab) + YERVOY
Patient Monitoring Checklist - OPDIVO® (nivolumab) + YERVOY

... WARNING: IMMUNE-MEDIATED ADVERSE REACTIONS YERVOY can result in severe and fatal immune-mediated adverse reactions. These immune-mediated reactions may involve any organ system; however, the most common severe immune-mediated adverse reactions are enterocolitis, hepatitis, dermatitis (including toxi ...
*** Drug Safety Alert *** Daliresp (Roflumilast) Tablets revisions to Prescribing Information
*** Drug Safety Alert *** Daliresp (Roflumilast) Tablets revisions to Prescribing Information

Assessing the Patient with Vestibular Symptoms
Assessing the Patient with Vestibular Symptoms

... Note: It is necessary to rule out central causes of dizziness (e.g. stroke, traumatic brain injury, cardiovascular disease, neurological disorders (Multiple Sclerosis), anxiety, and side effects from medications or street drugs.) ...
The World Federation of Hemophilia`s Sixth Global Forum The World
The World Federation of Hemophilia`s Sixth Global Forum The World

... that manufacturers demonstrate that their biosimilar product has no clinically meaningful differences from the licensed biologic in terms of safety, purity, and potency. A critical question for hemophilia patients is whether the potential risks associated with an abbreviated process for biologics wi ...
Topical Ivermectin 10 mg/g and Oral Doxycycline 40 mg Modified
Topical Ivermectin 10 mg/g and Oral Doxycycline 40 mg Modified

... to increased levels of cathelicidin. Activation of TLR2 leads to increased levels and activity of KLKs (e.g., KLK5), resulting in increased cleavage of cathelicidin to form LL-37, causing release of pro-inflammatory cytokines; mast cell activation, and macrophage and neutrophil chemotaxis. In respons ...
Bicillin CR Prescribing Information
Bicillin CR Prescribing Information

... adjacent to arteries, of Bicillin C-R and other penicillin preparations has resulted in severe neurovascular damage, including transverse myelitis with permanent paralysis, gangrene requiring amputation of digits and more proximal portions of extremities, and necrosis and sloughing at and surroundin ...
eMedicine - Pheochromocytoma - View Court Housing Co-op
eMedicine - Pheochromocytoma - View Court Housing Co-op

... encephalopathy, which is characterized by altered mental status, focal neurologic signs and symptoms, or seizures. Other neurologic complications include stroke due to cerebral infarction or an embolic event secondary to a mural thrombus from a dilated cardiomyopathy. Intracerebral hemorrhage also m ...
Anterior Retropharyngeal Approach to the Cervical Spine
Anterior Retropharyngeal Approach to the Cervical Spine

... Moreover, in case the occipito-atlantoaxial configuration is not disturbed, the stabilisation procedure excludes the occipito-axial joint, thus preserving the vital lateral rotatory movements at the neck. Thus, the technique is specially favourable for dealing with ventrally situated lesions extendi ...
product monograph - Eli Lilly Canada
product monograph - Eli Lilly Canada

... irritability, hypomania or mania, unusual changes in behaviour, and other symptoms, as well as the emergence of suicidality particularly within several weeks of starting treatment or changing the dose. Such symptoms should be reported immediately to healthcare providers. Such monitoring should inclu ...
Guidelines for the diagnosis and management of migraine in clinical practice
Guidelines for the diagnosis and management of migraine in clinical practice

Guidelines on the diagnosis and management of thrombotic
Guidelines on the diagnosis and management of thrombotic

... the regional UK registry occurred within 24 h of presentation, primarily in women (Scully et al, 2008). In the last 15 years there has been a marked increase in the understanding of the pathogenesis of TTP. It is now recognized that congenital and acute acquired TTP are due to a deficiency of von Wi ...
Acute Kidney Injury: Epidemiology, Diagnosis, Prognosis, and
Acute Kidney Injury: Epidemiology, Diagnosis, Prognosis, and

... occurred for AKI patients who need dialysis.6 The typical AKI patient is more complex clinically than they were 30 years ago,7 and is also more complex than the non-AKI patient;8-12 AKI tends to affect people of older age, who tend to have a higher rate of comorbidities and a greater likelihood of d ...
I.V. CIPRO
I.V. CIPRO

... CIPRO I.V. (ciprofloxacin) is a synthetic broad-spectrum antimicrobial agent for intravenous (I.V.) administration. Ciprofloxacin, a fluoro- Distribution quinolone, is 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1piperazinyl)- After intravenous administration, ciprofloxacin is present in saliva, nas ...
An update on the management of chronic hepatitis C: 2015
An update on the management of chronic hepatitis C: 2015

... failures. In addition, BOC and TVR required coadministration with PEG-IFN and RBV for 24 to 48 weeks, markedly increased the cost of therapy, and are associated with the emergence of resistance-associated variants (RAVs) in the majority of patients who fail treatment (3). The subsequent approval of ...
DRUG DESCRIPTION - Pharma Consult Website
DRUG DESCRIPTION - Pharma Consult Website

... occur over two months after the administration of antibacterial agents. If CDAD is suspected or confirmed, ongoing antibiotic use not directed against C. difficile may need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. difficile ...
Apomorphine 10 mg/ml Solution for Injection
Apomorphine 10 mg/ml Solution for Injection

... sometimes as many as 12 separate injections per day. It is recommended that the total daily dose of apomorphine HCl should not exceed 100mg and that individual bolus injections should not exceed 10mg. In clinical studies it has usually been possible to make some reduction in the dose of levodopa, th ...
INTERNAL MEDICINE JOURNAL
INTERNAL MEDICINE JOURNAL

... of innovation in high-tort-risk countries such as the US, England and Australia, the underpinning data in this regard are not robust. Dr Coates’ consideration of the situation in New Zealand provides an interesting insight in this context, given that New Zealand has a no fault compensation system, w ...
Varicose & Thread Vein Treatments PATIENT INFORMATION
Varicose & Thread Vein Treatments PATIENT INFORMATION

... Serious complications with foam sclerotherapy are rare but it is possible for any of the following to happen: allergic reactions, deep vein thrombosis (DVT), temporary eye sight disturbances, ulceration of skin. The most common problem with foam sclerotherapy is staining of the skin which can take ...
Interventions for enhancing medication adherence
Interventions for enhancing medication adherence

... the interested reader is referred to other sources (e.g., Burke 1997; Haynes 1979a; Houston 1997). Low adherence with prescribed treatments is very common. Typical adherence rates for prescribed medications are about 50% with a range from 0% to over 100% (Sackett 1979). To the extent that treatment ...
MPG201667_abs
MPG201667_abs

... enterography (MRE) evaluates the abdomen without radiation. The purpose of this study is to evaluate MRE in pediatric IBD. Methods: We performed an IRB-approved chart review from 2007–2010 on IBD patients at a tertiary referral pediatric hospital who underwent MRE. MRE findings, histology and labora ...
full-color
full-color

... Having participated in the organization of the Symposium and Courses with the most attractive and innovative topics in modern dermatovenereology, it is our exceptional honor, but also a great joy and pleasure, to greet you in the name of the Croatian Dermatovenereological Society of the Croatian Med ...
ocular complications due to intraoral local anesthesia: a case report
ocular complications due to intraoral local anesthesia: a case report

... Peñarrocha M, Sanchis JM. Ophthalmologic complications after intraoral local anesthesia with articaine. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000; 90(1): 21–24. Brain WR. Third nerve palsy following dental extraction. Arch Ophthalmol 1936;5:1164. Cooper JC. Deviation of eye and transient ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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