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Protocol - Doncaster LMC
Protocol - Doncaster LMC

... When a patient is prescribed a DMARD there are significant issues regarding pregnancy and family planning posed by the potency and potential teratogenic potential of these drugs. The decision about when and what drugs should be stopped is a decision that needs to be taken in secondary care. The deci ...
see here
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... screening clinics are now held at the Birmingham Children’s Hospital and the Queen Elizabeth Hospital, Birmingham where families can get advice on the best treatments available to maintain a good quality of life. One of these clinics runs alongside the annual family conference, which gives families ...
Guidelines for the management of vaginal discharge
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... prophylaxis and 50% recurrence within 6 months. ...
Fractional CO2
Fractional CO2

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Dysuria
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... intense that urination becomes complete misery. A Foley catheter until the symptoms resolve is merciful. Yeast, Trichomonas Pain on the vulva when urine passes over it can also be a symptom of yeast and less-commonly trichomonads. These infections should be apparent on inspection of the vulva/vagina ...
011 Myeloma revised 2015 - Directory of Cancer Services
011 Myeloma revised 2015 - Directory of Cancer Services

...  Offer Myeloma XI+ or any equivalent clinical trial if available.  The aim of induction therapy is to achieve the greatest depth of response using a stem cell-sparing regimen prior to consolidation with HDT and ASCT.  If no clinical trial was available, Bortezomib based combination regimens, such ...
CNS Infections
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Breakthrough Therapy - OSU CCTS
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Infection Control Policy
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Crimean-Congo hemorrhagic fever and pregnancy: Two
Crimean-Congo hemorrhagic fever and pregnancy: Two

... Tokat Province in Turkey is an endemic region for CCHF and most cases occur in this area. In 2011, two pregnant women diagnosed with CCHF were followed up in our hospital. CCHF was observed to progress more mildly in these cases. Both patients were fully recovered and discharged. During their follow ...
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Surgical Management of Bisphosphonate Related
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... can induce cell proliferation, cell senescence or apoptosis, according to the level of ROS production. These events can lead to preneoplastic lesions in the oral cavity and subsequent to malignancy in chronic use1. The malignant transformation rate of OSF has been reported to be around 7.6% over a 1 ...
Silver Hydrosol Informed Consent Agreement
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... The recommended use of this silver product does not apply to silver preparations other than those specifically chosen by this physician. The extremely dilute yet powerful form of this product, due to its uniform particle size, makes it ideal to (a) minimize all known risks associated with silver adm ...
Efficacy and Tolerability of the New Antiepileptic Drugs
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... Many of these studies resulted in the finding that two drugs were “equivalent” in their ability to control seizures. There is a great deal of controversy surrounding this outcome. The FDA does not accept such a finding as proof of efficacy, due to the possibility that two ineffective drugs might als ...
Clinical bulletin/Bowel management in multiple sclerosis
Clinical bulletin/Bowel management in multiple sclerosis

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Community Sequencing Program Sequencing Plans for 2007
Community Sequencing Program Sequencing Plans for 2007

... patients saw their symptoms decrease to half. In another study which combined Enbrel with methotrexate, 71 percent of patients taking both drugs experienced improvement compared to 27 percent who took only the methotrexate. Adverse Effects Mild to moderate injection site reactions were the most comm ...
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... High blood pressure (hypertension) is known to cause brain ageing, from memory problems through to frank dementia, and is common in older age, affecting 70% of people over 70 years of age. Low blood pressure (hypotension) may be an even greater risk factor for cognitive decline and dementia; as it i ...
9_0703_therapeutic streptokok.indd
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... onset form of the clinical picture as immune mediated OCD (NIMH, 2006). Because it is thought that PANDAS is caused by an autoimmune process, treatments with the potential to interrupt this process have been suggested for use. As a result, the use of immunoglobulins, prednisolone, and plasmapheresis ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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