University of Groningen Systemic inflammation and monocyte
... perform when epidural cocaine was available for the blocking of nerve trunks (5). Although surgery could now be practised without pain, surgery related mortality was still high due to blood loss and postoperative infection. In 1848, Semmelweis reported that fever and septicaemia in pregnant women co ...
... perform when epidural cocaine was available for the blocking of nerve trunks (5). Although surgery could now be practised without pain, surgery related mortality was still high due to blood loss and postoperative infection. In 1848, Semmelweis reported that fever and septicaemia in pregnant women co ...
A Way Out of the Inner Prison - Max-Planck
... after doctors had inserted implants in his jaw for a dental prosthesis. His tongue felt numb, his speech was slurred. His doctor said that his tongue needed to recover from the operation. But it didn’t get any better. A neurologist referred him to Tübingen Hospital. The diagnosis was sobering: “susp ...
... after doctors had inserted implants in his jaw for a dental prosthesis. His tongue felt numb, his speech was slurred. His doctor said that his tongue needed to recover from the operation. But it didn’t get any better. A neurologist referred him to Tübingen Hospital. The diagnosis was sobering: “susp ...
Orig Articles Aug pages 04 - South African Medical Journal
... Four (5%) of the children were lost to follow-up. All had been cared for by their mothers. Their ages at enrolment ranged from 5 to 72 months and the duration of treatment before exiting the programme ranged from 4 to 19 weeks. Their initial CD4 percentages ranged from 4.2% to 15.8% and the initial ...
... Four (5%) of the children were lost to follow-up. All had been cared for by their mothers. Their ages at enrolment ranged from 5 to 72 months and the duration of treatment before exiting the programme ranged from 4 to 19 weeks. Their initial CD4 percentages ranged from 4.2% to 15.8% and the initial ...
Malignant Otitis Externa - A Retrospective Study of 15 Patients
... He had a recurrence again after one year. The other patient had recurrence once after four months, which was treated successfully. Mortality because of MOE has dropped from 50% in an earlier report of Chandler to 0-15% reported by Naroznyet al.[3, 15] In a recent study, Loh et al reported a mortalit ...
... He had a recurrence again after one year. The other patient had recurrence once after four months, which was treated successfully. Mortality because of MOE has dropped from 50% in an earlier report of Chandler to 0-15% reported by Naroznyet al.[3, 15] In a recent study, Loh et al reported a mortalit ...
Chemotherapy versus hormonal treatment in platinum
... second-line chemotherapy. However, most treatment regimens induce toxicity, thus negatively influencing the quality of rather limited life spans. Here we evaluate whether a second-line chemotherapy can offer any benefit compared with a less toxic hormonal treatment. Patients and methods: Patients wi ...
... second-line chemotherapy. However, most treatment regimens induce toxicity, thus negatively influencing the quality of rather limited life spans. Here we evaluate whether a second-line chemotherapy can offer any benefit compared with a less toxic hormonal treatment. Patients and methods: Patients wi ...
Paediatric population
... The efficacy and safety of Metvix daylight photodynamic therapy (DL-PDT) was compared to Metvix conventional photodynamic therapy (c-PDT) in two randomised, investigator-blinded, comparative, intra-individual clinical studies conducted in Australia and Europe, including a total of 231 patients. Pati ...
... The efficacy and safety of Metvix daylight photodynamic therapy (DL-PDT) was compared to Metvix conventional photodynamic therapy (c-PDT) in two randomised, investigator-blinded, comparative, intra-individual clinical studies conducted in Australia and Europe, including a total of 231 patients. Pati ...
Applying Data Mining and Machine Learning Algorithms to predict
... IV that focus on non-motor symptoms are used infrequently. In most “PubMed” publications between 1998-2011, in all studies that have used UPDRS, 163 studies (97,6%) had included only UPDRS part III [4]. There are many different measures of PD symptoms describing actual patient state and their values ...
... IV that focus on non-motor symptoms are used infrequently. In most “PubMed” publications between 1998-2011, in all studies that have used UPDRS, 163 studies (97,6%) had included only UPDRS part III [4]. There are many different measures of PD symptoms describing actual patient state and their values ...
- Dr. Robert Fox
... • Current debate about "efficacy" --we use it when we are dealing with increased ESR, rash, or arthritis. Current debate is about "fatigue" only. • Efficacy in SLE was convincingly shown in "withdrawal studies," and those need to be done in SS patients. • Issue of cost/benefit of OCR monitor and tot ...
... • Current debate about "efficacy" --we use it when we are dealing with increased ESR, rash, or arthritis. Current debate is about "fatigue" only. • Efficacy in SLE was convincingly shown in "withdrawal studies," and those need to be done in SS patients. • Issue of cost/benefit of OCR monitor and tot ...
CG36 Atrial fibrillation
... 1 Note that risk factors are not mutually exclusive, and are additive to each other in producing a composite risk. Since the incidence of stroke and thromboembolic events in patients with thyrotoxicosis appears similar to that in patients with other aetiologies of AF, antithrombotic treatments shoul ...
... 1 Note that risk factors are not mutually exclusive, and are additive to each other in producing a composite risk. Since the incidence of stroke and thromboembolic events in patients with thyrotoxicosis appears similar to that in patients with other aetiologies of AF, antithrombotic treatments shoul ...
ORiordan-Pres
... • Becoming an epidemic both in the US and worldwide • Usually but not always associated with weight gain, FmHx DM, hyper-triglyceridemia and HTN • Important to exclude ETOH as the histologic pattern is identical • Natural history is unclear but up to 30% may develop significant fibrosis and cirrhosi ...
... • Becoming an epidemic both in the US and worldwide • Usually but not always associated with weight gain, FmHx DM, hyper-triglyceridemia and HTN • Important to exclude ETOH as the histologic pattern is identical • Natural history is unclear but up to 30% may develop significant fibrosis and cirrhosi ...
Tuberous Sclerosis - Viktor`s Notes for the Neurosurgery Resident
... target of rapamycin)* via GTPase-activating protein Rheb (Ras homolog enhanced in brain). *mTOR serves as major effector of cell growth (vs. cell proliferation) when mTOR is constitutively activated (through mutations in either hamartin or tuberin) this results in hamartomatous lesions high spontane ...
... target of rapamycin)* via GTPase-activating protein Rheb (Ras homolog enhanced in brain). *mTOR serves as major effector of cell growth (vs. cell proliferation) when mTOR is constitutively activated (through mutations in either hamartin or tuberin) this results in hamartomatous lesions high spontane ...
ITP: hematology`s Cosette from Les Mis ´erables
... owing to a block in early thymocyte development. Using thymocytes of the different genotypes, the authors showed that the various HDAC1/HDAC2 combinations result in different levels of overall deacetylase activity, with HDAC1 contributing to more activity than HDAC2. Based on the remarkable correlat ...
... owing to a block in early thymocyte development. Using thymocytes of the different genotypes, the authors showed that the various HDAC1/HDAC2 combinations result in different levels of overall deacetylase activity, with HDAC1 contributing to more activity than HDAC2. Based on the remarkable correlat ...
Infection of CNS.doc
... 2. Meningeal irritation sign: It is the inflammation of Meningeal, performed as nuchal rigidity, Kernig’s sign, Brudzinsik’s signs. 3. Nuchal rigidity：Nuchal rigidity is the inability to flex the head forward due to rigidity of the neck muscle; if flexion of the neck is painful but full range of mot ...
... 2. Meningeal irritation sign: It is the inflammation of Meningeal, performed as nuchal rigidity, Kernig’s sign, Brudzinsik’s signs. 3. Nuchal rigidity：Nuchal rigidity is the inability to flex the head forward due to rigidity of the neck muscle; if flexion of the neck is painful but full range of mot ...
How to Use an Article About Therapy or Prevention
... During the 1970s and early 1980s surgeons increasing undertook extracranial-intracranial bypass (that is, anastomosis of a branch of the external carotid artery, the superficial temporal, to a branch of the internal carotid artery, the middle cerebral). They believed it prevented strokes in patients ...
... During the 1970s and early 1980s surgeons increasing undertook extracranial-intracranial bypass (that is, anastomosis of a branch of the external carotid artery, the superficial temporal, to a branch of the internal carotid artery, the middle cerebral). They believed it prevented strokes in patients ...
Sciatica Sciatica is a general term used to describe pain in the back
... The sciatic nerve is a large nerve running from the lower part (lumbar and sacral areas) of your spine into your foot. Problems with the sciatic nerve can result from a disk herniation in the lower spine. You may also experience problems due to muscle spasm or joint dysfunction in any area between t ...
... The sciatic nerve is a large nerve running from the lower part (lumbar and sacral areas) of your spine into your foot. Problems with the sciatic nerve can result from a disk herniation in the lower spine. You may also experience problems due to muscle spasm or joint dysfunction in any area between t ...
Towards clinically useful neuro- imaging in psychiatric practice
... activity to sad facial processing. An equally innovative study11 developed this work, in the context of a randomised clinical trial, to correctly identify 70% of the patients who did not respond to antidepressant treatment and 89% of those who did. In this month’s Journal, Almeida et al12 provide ev ...
... activity to sad facial processing. An equally innovative study11 developed this work, in the context of a randomised clinical trial, to correctly identify 70% of the patients who did not respond to antidepressant treatment and 89% of those who did. In this month’s Journal, Almeida et al12 provide ev ...
Skill
... and how to manage them safely via CVAD Practice descriptor, i.e. can demonstrate skill used stating knowledge base and act appropriately at this level: Awareness of health and safety of chemotherapy administration, including protective clothing, safe handling and waste disposal. Adheres to local p ...
... and how to manage them safely via CVAD Practice descriptor, i.e. can demonstrate skill used stating knowledge base and act appropriately at this level: Awareness of health and safety of chemotherapy administration, including protective clothing, safe handling and waste disposal. Adheres to local p ...
035230 TRANXENE® T-TAB® Tablets TRANXENE®
... Since orally administered clorazepate dipotassium is rapidly decarboxylated to form nordiazepam, there is essentially no circulating parent drug. Nordiazepam, the primary metabolite, quickly appears in the blood and is eliminated from the plasma with an apparent half-life of about 40 to 50 hours. Pl ...
... Since orally administered clorazepate dipotassium is rapidly decarboxylated to form nordiazepam, there is essentially no circulating parent drug. Nordiazepam, the primary metabolite, quickly appears in the blood and is eliminated from the plasma with an apparent half-life of about 40 to 50 hours. Pl ...
Early recognition of life-threatening cervicofacial infections of dental
... anatomic cleavage plans and an aggressive evolution, with rapid deterioration of the general condition, jeopardizing the patient's life. ...
... anatomic cleavage plans and an aggressive evolution, with rapid deterioration of the general condition, jeopardizing the patient's life. ...
Simulect - Novartis Pharmaceuticals Corporation
... 729 patients were enrolled in the two studies using a dual maintenance immunosuppressive regimen comprised of cyclosporine, USP (MODIFIED) and corticosteroids, of which 363 patients were treated with Simulect and 358 patients were placebo-treated. Study 1 was conducted at 21 sites in Europe and Cana ...
... 729 patients were enrolled in the two studies using a dual maintenance immunosuppressive regimen comprised of cyclosporine, USP (MODIFIED) and corticosteroids, of which 363 patients were treated with Simulect and 358 patients were placebo-treated. Study 1 was conducted at 21 sites in Europe and Cana ...
Management of acute upper GI haemorrhage
... Ideally all patients who show active bleeding, or who have endoscopic stigmata of recent haemorrhage, should receive endoscopic therapy. In general this comprises: Injection of adrenaline – 1:10,000 adrenaline injected into 4 quadrants around the bleeding point, up to a maximum of 16mls. This will a ...
... Ideally all patients who show active bleeding, or who have endoscopic stigmata of recent haemorrhage, should receive endoscopic therapy. In general this comprises: Injection of adrenaline – 1:10,000 adrenaline injected into 4 quadrants around the bleeding point, up to a maximum of 16mls. This will a ...
Alefacept for Severe Alopecia Areata A Randomized, Double-blind, Placebo-Controlled Study
... randomized, double-blind, placebo-controlled trial, we demonstrate that a 12-week course of IM alefacept, 15 mg, does not effectively treat severe AA. In the enrolled population of patients, treatment with alefacept was well tolerated. Most AEs were rated as mild, and the AE profile was comparable w ...
... randomized, double-blind, placebo-controlled trial, we demonstrate that a 12-week course of IM alefacept, 15 mg, does not effectively treat severe AA. In the enrolled population of patients, treatment with alefacept was well tolerated. Most AEs were rated as mild, and the AE profile was comparable w ...
ASACOL
... Asacol tablets and periodically while on Asacol therapy. It is recommended that appropriate assessment and monitoring of liver function should be performed. ADVERSE REACTIONS Adverse Drug Reaction Overview Asacol is generally well tolerated. The most commonly reported adverse reactions were nausea, ...
... Asacol tablets and periodically while on Asacol therapy. It is recommended that appropriate assessment and monitoring of liver function should be performed. ADVERSE REACTIONS Adverse Drug Reaction Overview Asacol is generally well tolerated. The most commonly reported adverse reactions were nausea, ...
Management of multiple sclerosis
Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.