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Insulin-resistant diabetes service
Insulin-resistant diabetes service

... dysfunctional insulin receptors. Collectively, studies to date suggest that there is a clear and reproducible metabolic benefit from IGF-1 treatment, with the most impressive results having been reported with longer term use of very high doses, which have been reported to dramatically increase longe ...
Efficacy and Safety of Meriva®, a Curcumin
Efficacy and Safety of Meriva®, a Curcumin

... extrapolated from in vitro studies, but not validated clinically.2 This paradoxical situation is due to the poor stability of curcumin, which is highly unstable at intestinal pH (half-life at pH 7 <10 min),4 and low oral absorption. Plasma concentrations barely reach 50 ng/mL of phase II metabolites ...
PULMONARY HYPERTENSION
PULMONARY HYPERTENSION

... oral formulation (often starting with 0.1-0.2 mg oral as a single dose with doses up to 0.3 mg oral 3 times daily sometimes necessary). Intranasal DDAVP is not generally used until after the nose has healed and nasal congestion has improved. ...
Brain-metastases
Brain-metastases

... Tissue diagnosis (by stereotactic or open surgery) should be obtained when: (a) the primary tumor is unknown, (b) the systemic cancer is well controlled and the patient is a long-term survivor, (c) lesions on MRI do not show the typical aspect of brain metastases, (d) there is clinical suspicion of ...
Research Article The Influence of Coinfection on Mood States in
Research Article The Influence of Coinfection on Mood States in

... A cross-sectional design was used for this study. The participant pool was composed of volunteers, and sampling was conducted using a non-probabilistic technique (intentional sampling by convenience). The study was conducted at Instituto de Infectologia Emı́lio Ribas in São Paulo, Brazil, from May ...
Could muscle problems help explain movements in
Could muscle problems help explain movements in

... potential where potassium ions are moving out of the cells. In addition, the strength of the stimulus pulse required to trigger an action potential was much lower in HD fibers, suggesting that they are more easily triggered to contract. Not only that, but in several of the HD fibers, following a pul ...
Biologic Therapies for Crohn’s Disease: Update from the 2009 ACG Meeting
Biologic Therapies for Crohn’s Disease: Update from the 2009 ACG Meeting

... in the United States. Recent estimates place the preva­ lence of CD at 174–201 cases per 100,000 persons in the United States.2,3 Since 1991, the prevalence of CD has increased by approximately 31%.2 Research has demon­ strated a bimodal distribution of age at diagnosis, with a large peak in inciden ...
integrated care news
integrated care news

... Asthma is a chronic medical inflammatory condition of the airways that often results in a person experiencing breathing difficulties. It is considered a chronic condition because it interferes with daily functioning for more than three months a year and/or may cause prolonged hospitalization. Asthma ...
Systemic Corticosteroids
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... with varenicline, bupropion, and nortriptyline reliably increases long-term smoking abstinence rates and are significantly more ...
(PPI) Therapy in Patients with Functional Dyspepsia
(PPI) Therapy in Patients with Functional Dyspepsia

... were significantly more effective than placebo for reducing symptoms (relative risk reduction of about 10 percent, 95% CI 2.7-17.3 percent) [ 48] . In a stratified analysis, efficacy was confined to patients with ulcer-like and reflux-like symptoms, but not in those with dysmotility-like symptoms or ...
Allergy - Al-Huda International
Allergy - Al-Huda International

... • In an allergic person, the body mistakes the allergen for a harmful substance. This causes the cells to release substances, such as histamine. The release of histamine and other chemicals causes the body to experience an allergic reaction. • An allergic reaction may cause a runny nose, sneezing, i ...
藥物投遞系統
藥物投遞系統

... ˙ biodegradable (need not be removed surgically) △ disadvantage ˙ difficult to stop once injected ...
Ferrlecit - Sanofi US
Ferrlecit - Sanofi US

... The preservative benzyl alcohol has been associated with serious adverse events and death in pediatric patients. The ″gasping syndrome″ (characterized by central nervous system depression, metabolic acidosis, gasping respirations, and high levels of benzyl alcohol and its metabolites found in the bl ...
Pyothorax in Cats: A Review - VCA Specialty Animal Hospitals
Pyothorax in Cats: A Review - VCA Specialty Animal Hospitals

... infusion. Immediately following lipid infusion, ...
ACID REFLUX &amp; GERD: The Unsettling
ACID REFLUX & GERD: The Unsettling

... Many who have an acid-related disease (ARD), such as GERD, wait an average of over two years before talking with their physician about their problem.1 Although various lifestyle factors are associated with GERD, when symptoms are present, the clinical evidence reveals that lifestyle changes usually ...
Henoch-Schönlein purpura (immunoglobulin A vasculitis
Henoch-Schönlein purpura (immunoglobulin A vasculitis

... findings between patients with recurrent disease and those without recurrence. The reasons for these differences between study results are unclear. Morbidity in the initial phase of HSP (IgAV) is primarily a result of gastrointestinal complications, including intussusception and, less commonly, bow ...
PDF for - Actual Gynecology And Obstetrics
PDF for - Actual Gynecology And Obstetrics

... Combined oral contraceptives (COC) The use of combined hormonal contraceptives, i.e. estrogene–gestagene preparations, is the basis of pharmaceutical treatment of endometriosis. If pain is the dominating symptom, and the patient is not trying for pregnancy, COC may be applied empirically, without la ...
Antithrombotic Therapy for Venous Thromboembolic Disease
Antithrombotic Therapy for Venous Thromboembolic Disease

... - The severity of symptoms may vary over time, and the most extreme manifestation is a venous ulcer of the lower leg. ...
Theatre Protocol for Infected Cases
Theatre Protocol for Infected Cases

... to a vulnerable site on the same patient or another patient. Practices to prevent patients acquiring infection and to minimise the risk of transmission should therefore be incorporated into routine practice. (Wilson, 2006). This protocol intends to give general guidance to theatre and recovery pract ...
LDN and CFS and Fibromyalgia
LDN and CFS and Fibromyalgia

... Syndrome: A Systematic Review. • This review of 26 studies found that adults who met the CDC criteria of CFS had a poor prognosis with less than 10% recovering and the majority do not improve over time with standard medical care. ...
Painful Bladder Syndrome/Interstitial Cystitis and Related Disorders
Painful Bladder Syndrome/Interstitial Cystitis and Related Disorders

... Global Response Assessment (GRA) It has been not only a difficult condition to diagnose but also a difficult condition for which to assess therapeutic impact. In a chronic, devastating condition with primarily subjective symptomatology, no known cause, and no cure, patients are desperate and often s ...
ACTUALITATI IN TERAPIA SCLEROZEI MULTIPLE Caciulata 2007
ACTUALITATI IN TERAPIA SCLEROZEI MULTIPLE Caciulata 2007

Core Safety Profile (CSP) for timolol,
Core Safety Profile (CSP) for timolol,

... Like other topically applied ophthalmic agents, timolol maleate is absorbed systemically. Due to beta-adrenergic component, timolol maleate, the same types of cardiovascular, pulmonary and other adverse reactions seen with systemic beta-adrenergic blocking agents may occur. Incidence of systemic ADR ...
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View PDF

... central nervous system remains confusing[6]. Neuromyelitis optica has recently been recognized as distinct from prototypic multiple sclerosis, but the differences are not fully understood, especially at first presentation with isolated optic neuritis[7]. The discovery of the neuromyelitis optica (NM ...
VBF! - Vascular Birthmarks Foundation
VBF! - Vascular Birthmarks Foundation

... ? AVM is a complex mass of arteries and veins. Defective blood flow has been associated with these lesions. As the lesion ages, the vessels enlarge and thicken to compensate for the increased blood supply. There are two grades: low and high. Low grade grow slowly with the child, and high grade expan ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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