Etanercept and Infliximab for the treatment of Rheumatoid Arthritis
... DAS28 score of ≥ 1.2 in the absence of severe drug related toxicity. After initial response DAS28 should be monitored at least every 6 months and treatment withdrawn if improvement is not maintained. Complete new application if alternative biologic drug has to be used due to adverse event before ini ...
... DAS28 score of ≥ 1.2 in the absence of severe drug related toxicity. After initial response DAS28 should be monitored at least every 6 months and treatment withdrawn if improvement is not maintained. Complete new application if alternative biologic drug has to be used due to adverse event before ini ...
Early Ambulation After Acute Deep Vein Thrombosis
... if there is a suspected DVT or if an ultrasound result is pending? (2) Once a DVT is diagnosed and the patient is placed on anticoagulant therapy using enoxaparin (Lovenox®), how long until the patient is out of bed and/or ambulating? (3) With DVTs, are bed exercises on the unaffected limbs allowed? ...
... if there is a suspected DVT or if an ultrasound result is pending? (2) Once a DVT is diagnosed and the patient is placed on anticoagulant therapy using enoxaparin (Lovenox®), how long until the patient is out of bed and/or ambulating? (3) With DVTs, are bed exercises on the unaffected limbs allowed? ...
Procedures of Limited Clinical Priority Guideline
... may be exceptional clinical circumstances in which to fund these interventions. Whilst it is not feasible to consider every possible scenario within this document, they will be considered on a case by case basis to enable due consideration of the individual merits of each case. Thus, funding for ‘in ...
... may be exceptional clinical circumstances in which to fund these interventions. Whilst it is not feasible to consider every possible scenario within this document, they will be considered on a case by case basis to enable due consideration of the individual merits of each case. Thus, funding for ‘in ...
London, 22 October 2009 * COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE
... In the context of insufficient long-term efficacy of available treatments, and high level of associated non-compliance, morbidity and considerably shortened life expectancy, there is a need for new medicinal products to treat pulmonary disease and infections and exocrine pancreatic insufficiency and ...
... In the context of insufficient long-term efficacy of available treatments, and high level of associated non-compliance, morbidity and considerably shortened life expectancy, there is a need for new medicinal products to treat pulmonary disease and infections and exocrine pancreatic insufficiency and ...
DBS Therapy for Parkinson`s Disease
... management of chronic, intractable (drug refractory) primary dystonia, including generalized and segmental dystonia, hemidystonia, and cervical dystonia (torticollis), for individuals 7 years of age and older. Contraindications: Contraindications include patients who will be exposed to MRI using a f ...
... management of chronic, intractable (drug refractory) primary dystonia, including generalized and segmental dystonia, hemidystonia, and cervical dystonia (torticollis), for individuals 7 years of age and older. Contraindications: Contraindications include patients who will be exposed to MRI using a f ...
full research - Edison Investment Research
... extrapyramidal side effects (EPS) such as dystonia, movement disorders or neuroleptic malignant syndrome. APs are also D2-receptor antagonists, but also block receptor subtypes, notably serotonin-2A (5-HT2A), and have a lower risk of EPS than FGAs. Benzodiazepines (which act on the GABA brain recep ...
... extrapyramidal side effects (EPS) such as dystonia, movement disorders or neuroleptic malignant syndrome. APs are also D2-receptor antagonists, but also block receptor subtypes, notably serotonin-2A (5-HT2A), and have a lower risk of EPS than FGAs. Benzodiazepines (which act on the GABA brain recep ...
Antibiotic therapy in autoimmune disorders
... of the tonsils or the skin. In this disease, antibodies against group A b-hemolytic Streptococcus are also active against host target, including the heart and joints. Antibiotic treatment with penicillin is known to prevent the autoimmune reaction when given during the acute infection, or may preven ...
... of the tonsils or the skin. In this disease, antibodies against group A b-hemolytic Streptococcus are also active against host target, including the heart and joints. Antibiotic treatment with penicillin is known to prevent the autoimmune reaction when given during the acute infection, or may preven ...
TREATING CHRONIC LYME DISEASE TYPES OF LYME DISEASE
... Cefuroxime (Ceftin) Clarithromycin (Biaxin) Azithromycin Metronidazole (Flagyl) Rifampin ...
... Cefuroxime (Ceftin) Clarithromycin (Biaxin) Azithromycin Metronidazole (Flagyl) Rifampin ...
Injectable Drugs Requiring Prior Authorization
... 7) Limb spasticity due to multiple sclerosis, spinal cord injury or after stroke with documented functional impairment, hygiene complications or infection due to spasticity. 8) For prevention of migraine, must meet all the following criteria: a) Meet diagnostic criteria for migraine or migraine with ...
... 7) Limb spasticity due to multiple sclerosis, spinal cord injury or after stroke with documented functional impairment, hygiene complications or infection due to spasticity. 8) For prevention of migraine, must meet all the following criteria: a) Meet diagnostic criteria for migraine or migraine with ...
radiation therapy oncology group rtog 92-02 a phase iii trial
... retropubic prostatectomy and were found at time of surgery to have positive pelvic lymph nodes14. Fortyeight patients received hormonal manipulation in the form of an orchiectomy or estrogen administration but the remaining patients received hormonal manipulation only at the time of relapse. For the ...
... retropubic prostatectomy and were found at time of surgery to have positive pelvic lymph nodes14. Fortyeight patients received hormonal manipulation in the form of an orchiectomy or estrogen administration but the remaining patients received hormonal manipulation only at the time of relapse. For the ...
5.01.558 Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9
... childhood. Total cholesterol levels in HeFH range from 350 to 550 mg/dL, which can result in premature ASCVD. Aggressive lipid-lowering therapy is recommended to achieve LDL-C reductions of at least 50%. Both children and adults with LDL-C levels of ≥ 190 mg/dL, following lifestyle modifications wil ...
... childhood. Total cholesterol levels in HeFH range from 350 to 550 mg/dL, which can result in premature ASCVD. Aggressive lipid-lowering therapy is recommended to achieve LDL-C reductions of at least 50%. Both children and adults with LDL-C levels of ≥ 190 mg/dL, following lifestyle modifications wil ...
castration-resistant prostate cancer
... sixth leading cause of cancer mortality in men worldwide.1 In most developed countries, PrCa has become the leading cancer in men, mainly due to lifestyle factors and the spread of prostate specific antigen (PSA) screening. During the last 25 years, the advances in PrCa diagnosis and treatment have ...
... sixth leading cause of cancer mortality in men worldwide.1 In most developed countries, PrCa has become the leading cancer in men, mainly due to lifestyle factors and the spread of prostate specific antigen (PSA) screening. During the last 25 years, the advances in PrCa diagnosis and treatment have ...
End-of-Life Options for Patients with Advanced Heart Failure
... resuscitation. At the start of the Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments trial, only 23% of patients with HF did not want to be resuscitated, and 2 months later, 40% of those changed their minds (at the 2-month follow-up, only 14% of those who initially w ...
... resuscitation. At the start of the Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments trial, only 23% of patients with HF did not want to be resuscitated, and 2 months later, 40% of those changed their minds (at the 2-month follow-up, only 14% of those who initially w ...
Centre for Philosophy of Natural and Social Science
... being claimed to be a sine qua non of a truly scientifically convincing trial. In fact, when it comes to detailed exposition and defence, all treatments make weaker, more guarded claims. But even those who allow that, at least under some conditions, some useful and "valid" information can sometimes ...
... being claimed to be a sine qua non of a truly scientifically convincing trial. In fact, when it comes to detailed exposition and defence, all treatments make weaker, more guarded claims. But even those who allow that, at least under some conditions, some useful and "valid" information can sometimes ...
Alcoholism Treatment in the United States An Overview
... treatment in either inpatient or outpatient settings. For many of those patients, detoxification—with or without pharmacotherapy—is the first step of treatment. The major behavioral approaches currently used in alcoholism treatment include cognitive-behavioral therapy, motivational enhancement thera ...
... treatment in either inpatient or outpatient settings. For many of those patients, detoxification—with or without pharmacotherapy—is the first step of treatment. The major behavioral approaches currently used in alcoholism treatment include cognitive-behavioral therapy, motivational enhancement thera ...
CLINICAL PRACTICE GUIDELINES FORTHE MANAGEMENT OF
... There are no definite guidelines available for GAD. Anxiety symptoms are prevalent in primary care settings. These symptoms are a source of considerable morbidity The role of combined treatment is strongly felt in the management of GAD. Benzodiazepines (BZDs) have been extensively used for the treat ...
... There are no definite guidelines available for GAD. Anxiety symptoms are prevalent in primary care settings. These symptoms are a source of considerable morbidity The role of combined treatment is strongly felt in the management of GAD. Benzodiazepines (BZDs) have been extensively used for the treat ...
The Global Leader in Liver Cell Therapies
... ACLF – High-Mortality Condition in Need of Paradigm Shift Acute-on-Chronic Liver Failure is a market underserved by innovative therapies Acute deterioration of liver function, rapidly evolving multi-organ failure Est. 60-90k patients p.a. in the USA/EU/Japan, grade 1 &2* High short-term mortality r ...
... ACLF – High-Mortality Condition in Need of Paradigm Shift Acute-on-Chronic Liver Failure is a market underserved by innovative therapies Acute deterioration of liver function, rapidly evolving multi-organ failure Est. 60-90k patients p.a. in the USA/EU/Japan, grade 1 &2* High short-term mortality r ...
Craniosacral Therapy - Milestone Centers, Inc.
... although there have been claims that it has been helpful. More research needs to be done. ...
... although there have been claims that it has been helpful. More research needs to be done. ...
GP information sheet - Phenelzine (Nardil )
... Phenelzine should not be used in patients who are hypersensitive to any of the ingredients or with phaeochromocytoma, cerebrovascular disease, congestive heart failure, a history of liver disease or with abnormal liver function tests. Phenelzine should not be administered at the same time as, or w ...
... Phenelzine should not be used in patients who are hypersensitive to any of the ingredients or with phaeochromocytoma, cerebrovascular disease, congestive heart failure, a history of liver disease or with abnormal liver function tests. Phenelzine should not be administered at the same time as, or w ...
Can measurement of peak expiratory flow enhance compliance in
... benefit from self-measurement of PEF. Having first been taught how to perform the test correctly and plot the recordings graphically, the patient should measured PEF twice or three times daily for about ten days. Subsequent perusal and discussion of the record with the doctor will give the patient c ...
... benefit from self-measurement of PEF. Having first been taught how to perform the test correctly and plot the recordings graphically, the patient should measured PEF twice or three times daily for about ten days. Subsequent perusal and discussion of the record with the doctor will give the patient c ...
Guideline for diagnosis and treatment of adult bronchiectasis
... bronchopulmonary secretions, improve efficiency of ventilation, maintain or improve exercise tolerance, and reduce breathlessness and (thoracic) pain There are a wide variety of available airway clearance techniques and patients are encouraged to choose ones that they are comfortable with We rec ...
... bronchopulmonary secretions, improve efficiency of ventilation, maintain or improve exercise tolerance, and reduce breathlessness and (thoracic) pain There are a wide variety of available airway clearance techniques and patients are encouraged to choose ones that they are comfortable with We rec ...
Clinical Practice Guide in Erectile Dysfunction
... Erectile dysfunction may occur regardless of the postpubertal age and there are many underlying aetiological factors. It is noteworthy that erectile dysfunction might not be the primary complaint and/or be associated with other sexual problems. Sexuality, including erection, is a complex biopsychos ...
... Erectile dysfunction may occur regardless of the postpubertal age and there are many underlying aetiological factors. It is noteworthy that erectile dysfunction might not be the primary complaint and/or be associated with other sexual problems. Sexuality, including erection, is a complex biopsychos ...
Session 10. Standard Treatment Guidelines
... oral rehydration therapy is effective in reducing morbidity and mortality. Other common problems are making incorrect medicine choices, overdosing, underdosing, and choosing a more expensive medicine when less expensive ones would be equally or more effective. STGs—also known as standard treatment s ...
... oral rehydration therapy is effective in reducing morbidity and mortality. Other common problems are making incorrect medicine choices, overdosing, underdosing, and choosing a more expensive medicine when less expensive ones would be equally or more effective. STGs—also known as standard treatment s ...
IRRITABLE BOWEL SYNDROME (IBS)
... anxiety that is worsening their irritable bowel syndrome symptoms. However, these drugs should only be taken for short periods of time since they can be addictive. ...
... anxiety that is worsening their irritable bowel syndrome symptoms. However, these drugs should only be taken for short periods of time since they can be addictive. ...
Management of multiple sclerosis
Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.