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Central serous chorioretinopathy: a pathogenetic model Clinical Ophthalmology Dove
Central serous chorioretinopathy: a pathogenetic model Clinical Ophthalmology Dove

... vasoconstriction. Ketoconazole exerts its effects by inhibiting some steps in the steroid synthesis resulting in decreased ­levels of cortisol, androgen, and aldosterone and in elevated progesterone. These effects seem to be present at the minimum dosage of 400 mg/day. An additional action of ketoco ...
inside - Australian Doctor
inside - Australian Doctor

... Nervous system involvement is again less common but, as with cardiac involvement, may cause significant morbidity and mortality. Up to 5% of patients have neurological involvement and, ...
5
5

... large variation in LBP diagnoses, and a multitude of poorly studied interventions.4 It has been assumed that randomized controlled trials (RCTs) could provide answers to questions such as ‘which intervention is most effective for which patient’, but after the publication of more than 1,000 RCTs focu ...
Therapy of myositis: biological and physical
Therapy of myositis: biological and physical

... extension revealed that only quadriceps strength improvement was sustained whereas all other variables returned to the baseline values, indicating that continuing exercise is necessary to maintain and improve function and health. Eight patients with JDM in remission but with muscle impairment, ages ...
Clinical Bulletin - National Multiple Sclerosis Society
Clinical Bulletin - National Multiple Sclerosis Society

... slowly titrated up to minimize sedation and to identify the lowest effective dose. Patients and family members become adept at making minor dose adjustments to control changes in tone that occur secondary to infection, stress, and other causes previously discussed. Patients may experience fatigue or ...
Jelly Fish Anaphylaxis
Jelly Fish Anaphylaxis

... 7. C Loten, B Stokes, D Worsley, J Seymour, S Jiang, G Isbister. A randomised controlled trial of hot water (45°C) immersion versus ice packs for pain relief in bluebottle stings. MJA April 2006. 184(7):329-333. 8. Russo, A.J.; Calton, G.J.; Burnett, J.W. The relationship of the possible allergic re ...
Lower urinary tract symptoms and benign prostatic hyperplasia
Lower urinary tract symptoms and benign prostatic hyperplasia

... Given that different classes of drugs target different LUTS, some patients respond better to a combination of drugs from different classes rather than using separate drugs in isolation. In general, the authors tend to prescribe tamsulosin 400 µg/day as a first-line medication for men with LUTS. This ...
ZONALON® (doxepin hydrochloride) CREAM, 5% FOR TOPICAL
ZONALON® (doxepin hydrochloride) CREAM, 5% FOR TOPICAL

... may vary and is dependent upon the particular MAO inhibitor being used, the length of time it has been administered, and the dosage involved. Cimetidine: Serious anticholinergic symptoms (i.e., severe dry mouth, urinary retention and blurred vision) have been associated with elevations in the serum ...
Veterinary Homeopathy
Veterinary Homeopathy

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InterStim Therapy for Urinary Incontinence
InterStim Therapy for Urinary Incontinence

... patients who have failed or are not candidates for more conservative treatments. Contraindications: Diathermy. Patients who have not demonstrated an appropriate response to test stimulation or are unable to operate the neurostimulator. Precautions/Adverse Events: Safety and effectiveness have not be ...


... performed seven (7) days after IVIG, revealing blood pressures of 106/61 mmHg when supine and 103/71 mmHg in a head-up position. These results suggest that IVIG should be considered as a choice to treat early AIAN. ...
GM1 Gangliosidosis
GM1 Gangliosidosis

Hydroxyethyl starch 130/0.38-0.45 versus crystalloid or albumin in
Hydroxyethyl starch 130/0.38-0.45 versus crystalloid or albumin in

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skin - The Dermatologist
skin - The Dermatologist

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Shortage memo phenotolamine and phenoxybenzamine
Shortage memo phenotolamine and phenoxybenzamine

... chromaffin cells of the adrenal medulla. Although it may be malignant, symptoms usually result from the excess secretion of catecholamines 2 and include hypertension, headaches, palpitations, and excessive sweating. If the effects of the release of catecholamines are not controlled, a life-threateni ...
October 2008
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Mark Berry
Mark Berry

... 2006 – by joking that he “dreams about this place”. But really, said Gibson, the idea is to stop people dreaming…”because the thing about dreams is, then you wake up!”. Gibson seemed to feel the same sense of hope and excitement that many of the people I spoke to at the conference expressed: “Things ...
RISPERDAL CONSTA - Dosing - Dosage and Administration
RISPERDAL CONSTA - Dosing - Dosage and Administration

... for the maintenance treatment of Bipolar I Disorder is 25 mg intramuscular injection every 2 weeks. Some patients not responding to 25 mg may benefit from a higher dose of 37.5 mg or 50 mg every 2 weeks.1 A lower initial dose of RISPERDAL CONSTA 12.5 mg may be appropriate when clinical factors warra ...
Vaccination of Patients with Small-Cell Lung Cancer with Synthetic
Vaccination of Patients with Small-Cell Lung Cancer with Synthetic

... Six patients were enrolled at the 30-␮g dose level, and five patients were enrolled at the 10- and 3-␮g dose levels. Baseline patient characteristics are specified in Table 1. Three patients at the 30-␮g dose level and one patient at the 3-␮g dose level received five of six planned injections, and t ...
A Decade of Innovation in Rare Diseases
A Decade of Innovation in Rare Diseases

... exploring use of TKIs in combination with other cancer-fighting agents.31 As knowledge of the underlying disease pathway has grown, researchers have also identified a new mechanism of action for combatting CML. In 2012, the FDA approved a new, first-inclass treatment called omacetaxine mepusuccinate ...
Jemds.com
Jemds.com

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summary - USDOCTOR.com
summary - USDOCTOR.com

... engaging in illegal conduct that gave certain contractors “most favored nation” status . These alleged illegal acts were systematic and pervasive (See Exhibit 2). In 1995, Blue Cross/Blue Shield of Michigan paid a total of $51.6 million to settle charges that it falsified audit reports and used Medi ...
Myositis 101 - The Myositis Association
Myositis 101 - The Myositis Association

... treatment in a month or two, showing improvement in blood tests and in physical strength. More difficult cases may have flares that last a year or longer, and some cases respond immediately, with no reoccurrence. IBM patients have a slow-progressing disease, with no effective treatment. Patients dia ...
myositis 101 - The Myositis Association
myositis 101 - The Myositis Association

... treatment in a month or two, showing improvement in blood tests and in physical strength. More difficult cases may have flares that last a year or longer, and some cases respond immediately, with no reoccurrence. IBM patients have a slow-progressing disease, with no effective treatment. Patients dia ...
the 2014 HIV/STD Update
the 2014 HIV/STD Update

... • Modest reduction in EFV levels does not appear to reduce EFV activity • EFV-based ART (600 mg) with RIFbased TB therapy is regimen of choice ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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