What are Stem Cells? - Science and Today`s Headlines
... Our group choose the question: How is it possible to obtain embryonic stem cells and is it also possible to obtain adult stem cells? because we did not know much on the subject, so the question seemed very appealing and we wanted to learn more about it. ...
... Our group choose the question: How is it possible to obtain embryonic stem cells and is it also possible to obtain adult stem cells? because we did not know much on the subject, so the question seemed very appealing and we wanted to learn more about it. ...
Introduction 1. Definition 1.1 Stem cells are those cells which are
... 1. This paper provides the basic information about pluripotent stem cells and how scientists convert somatic cells into pluripotent cells. 2. There are 4 techniques applied to induce the pluripotent stem cells which are 2.1 Nuclear transfer 2.2 Cell fusion 2.3 Direct reprogramming 2.4 Cell culture S ...
... 1. This paper provides the basic information about pluripotent stem cells and how scientists convert somatic cells into pluripotent cells. 2. There are 4 techniques applied to induce the pluripotent stem cells which are 2.1 Nuclear transfer 2.2 Cell fusion 2.3 Direct reprogramming 2.4 Cell culture S ...
Max-Planck-Institut für molekulare Biomedizin
... groundbreaking success. Embryonic stem cells are pluripotent, which means that they can make each of the more than 200 types of body cells, including germ cells. Yet until then, the latter was not possible. Hans Schöler’s work thus provided the last piece of evidence for the pluripotency of embryoni ...
... groundbreaking success. Embryonic stem cells are pluripotent, which means that they can make each of the more than 200 types of body cells, including germ cells. Yet until then, the latter was not possible. Hans Schöler’s work thus provided the last piece of evidence for the pluripotency of embryoni ...
Stem cells
... • The ability to differentiate into all three germ layers – ectoderm, mesoderm, endoderm (in vitro and in vivo) • Lineage specific markers: – Meso (muscles – skeletal, cardiac, blood …) – Ecto (skin, neuronal cells - CNS …) – Endo (digestive tube + derivatives) ...
... • The ability to differentiate into all three germ layers – ectoderm, mesoderm, endoderm (in vitro and in vivo) • Lineage specific markers: – Meso (muscles – skeletal, cardiac, blood …) – Ecto (skin, neuronal cells - CNS …) – Endo (digestive tube + derivatives) ...
Stem Cell
... transfer involves the injection of a somatic nucleus into an enucleated oocyte, which, upon transfer into a surrogate mother, can give rise to a clone (“reproductive cloning”), or, upon explanation in culture, can give rise to genetically matched embryonic stem (ES) cells (“somatic cell nuclear tran ...
... transfer involves the injection of a somatic nucleus into an enucleated oocyte, which, upon transfer into a surrogate mother, can give rise to a clone (“reproductive cloning”), or, upon explanation in culture, can give rise to genetically matched embryonic stem (ES) cells (“somatic cell nuclear tran ...
Reprogramming somatic cells into iPS cells to generate an in vitro
... It was recently reported that human somatic adult cells, such as skin fibroblasts, can be reprogrammed to an embryonic stage, known as induced pluripotent stem cells (iPSCs). Such iPSCs closely resemble human Embryonic Stem Cells (hESCs), since they can be indefinitely propagated in vitro and differ ...
... It was recently reported that human somatic adult cells, such as skin fibroblasts, can be reprogrammed to an embryonic stage, known as induced pluripotent stem cells (iPSCs). Such iPSCs closely resemble human Embryonic Stem Cells (hESCs), since they can be indefinitely propagated in vitro and differ ...
basic characterisation of hiPSC.
... Expression of key endogenous pluripotency-associated genes Evidence of transgene silencing ...
... Expression of key endogenous pluripotency-associated genes Evidence of transgene silencing ...
Induced stem cells
Induced stem cells (iSC) are stem cells artificially derived from somatic, reproductive, pluripotent or other cell types by deliberate epigenetic reprogramming. They are classified as either totipotent (iTC), pluripotent (iPSC) or progenitor (multipotent—iMSC, also called an induced multipotent progenitor cell—iMPC) or unipotent -- (iUSC) according to their developmental potential and degree of dedifferentiation. Progenitors are obtained by so-called direct reprogramming or directed differentiation and are also called induced somatic stem cells.Three techniques are widely recognized: Transplantation of nuclei taken from somatic cells into an oocyt (egg cell) lacking its own nucleus (removed in lab) Fusion of somatic cells with pluripotent stem cells and Modification of somatic cells, inducing its transformation into a stem cell, using: the genetic material encoding reprogramming protein factors, recombinant proteins; microRNA, a synthetic, self-replicating polycistronic RNA, and low-molecular weight biologically active substances.↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑