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MicroRNAs: Loquacious Speaks out
MicroRNAs: Loquacious Speaks out

... Goettingen, Germany. DOI: 10.1016/j.cub.2005.07.043 ...
Beta sheets are twisted
Beta sheets are twisted

... • Electrophoresis is a method for separating proteins based on how they move in an electric field • Image to the left is an electrophoretogram of serum, stained with amido black • The sample starts at the top, an electric field is applied, and proteins migrate • The molecules at the bottom are the l ...
Document
Document

... expression of Thr309Lys mutated human FXII (hFXII_Thr309Lys) by a tetracycline (Tet)regulated system. (A) Schematic outline of the tetracycline-controlled transactivator system used in this study. The LAP promoter restricts expression of the regulatory protein tTA to the liver. In the absence of tet ...
Transport in Plants I - Western Washington University
Transport in Plants I - Western Washington University

... plants, fungus, yeast animals, plants, fungus, yeast bacteria, animals, plants, etc. ...
Non-linear optimization
Non-linear optimization

... QCQPs can be solved more efficiently than SDPs (O(n3) <-> O(n4.5)) Interior point methods ...
Module name Bioinformatics Module code B
Module name Bioinformatics Module code B

... bioinformatics tools for searching DNA/ protein sequence databases and principles of DNA/protein structural bioinformatics. This course provides students with an overview of protein bioinformatics including computational and experimental approaches. It will introduce DNA, amino acid and protein phys ...
proteins - Chavis Biology
proteins - Chavis Biology

... Functions of Globular Proteins Transport proteins function in the movement of other substances – Hemoglobin, the iron containing protein in blood, transport oxygen from lungs to other parts of the body (C3032H4816O872N780S9Fe4) – Membrane transport proteins such as channels for potassium and water ...
On the Importance of Amino Acid Sequence and Spatial Proximity of
On the Importance of Amino Acid Sequence and Spatial Proximity of

... We discuss here the paper by Mittal et al. (1), which claims that stoichiometry plays a key role in protein folding. Though the very use of the term stoichiometry seems to be unjustified in this context, we will follow the authors’ definition of stoichiometry in order to discuss the results, the way ...
Defense - Gerstein Lab
Defense - Gerstein Lab

... 16S analysis of GOS data reveals that most sequences fall into 5 ribotypes However, there were very few identical sequences, suggesting that no two cells have identical genome sequences Eugene V Koonin Nat Biotechnology, 2007 ...
15-25 kD
15-25 kD

... • Changes in DNA lead to proteins with: – Different functions – Novel traits – Positive, negative, or no effects • Genetic diversity provides pool for natural ...
Active Transport Moves solute Against Their Electrochemical
Active Transport Moves solute Against Their Electrochemical

... Voltage-gated ion channels have specialized charged protein domains called voltage sensor that are extremely sensitive to changes in the membrane potential: changes above a certain threshold value exert sufficient electrical force on those domain to encourage to channel to switch from its closed to ...
NIDA-svisit-20071219-PARE - Yale Bioinformatics -
NIDA-svisit-20071219-PARE - Yale Bioinformatics -

... Gene expression major place for regulation (easy to measure) ...
Cell Physiology
Cell Physiology

... In primary active transport, the energy is derived directly from breakdown of adenosine triphosphate (ATP) or of some other high-energy phosphate compound. In secondary active transport, the energy is derived secondarily from energy that has been stored in the form of ionic concentration differences ...
Organic Compounds The Big Four
Organic Compounds The Big Four

... 5. Would it be valid to conclude that if a base were added to a reaction the rate of the reaction would slow down? – The blue line shows that the pressure of oxygen was lower when the base was added, so yes, this would be a valid conclusion ...
Proteins We now know about the building blocks of proteins (amino
Proteins We now know about the building blocks of proteins (amino

... • Notice that we lose the negative charge on the a carboxylate and a positive charge on an amino group. • This loss is why the pKa of an amino acid side chain is different when part of a protein as compared to a free amino acid. - the COO- is no longer ___________ - the NH3+ is no longer __________ ...
CH05_Lecture
CH05_Lecture

... 1. Nonpolar regions that insert into the internal portion of the lipid bilayer 2. Chemical bonding domains that link directly to proteins ...
Metals in Redox Biology - University of Nebraska–Lincoln
Metals in Redox Biology - University of Nebraska–Lincoln

... MOLECLUAR CHAPERONES FOR FE-S CLUSTER ASSEMBLY -Isc pathway : contains HscA and HscB proteins homologues of the DnaJ and DnaK molecular chaperones. -This interaction is enhanced by HscB, which can bind to both IscU and HscA, leading to a strong enhancement of the intrinsic HscA ATPase activity. -Hsc ...
Gene
Gene

... a. Compare the healthy protein with the mutated protein strand. List the number of amino acids that are different in the mutated strand compared with the healthy strand. b. This type of mutation is called a deletion. Explain why this is a good name for this kind of mutation. ...
Midterm Exam Key
Midterm Exam Key

... o. NADH dehydrogenase p. stearic acid q. voltage-gated Na+ channel r. oxygen s. NADH t. K+ u. H+ v. cytochrome oxidase ...
SIGNAL TRANSDUCTION PATHWAYS Outline
SIGNAL TRANSDUCTION PATHWAYS Outline

... Once the receptor-ligand complex is inside the nucleus, it functions to: 1) Transcribe genes/synthesize mRNA 2) Regulate gene function (determine which genes are turned on/off) 3) Regulate many different genes at the same time ...
How do we purify proteins? GFP as model system to learn
How do we purify proteins? GFP as model system to learn

... Lactate , pyruvate and NAD+ are recognized by lactate dehydrogenase Nickel and histidine tag proteins ...
Introduction
Introduction

... Three main classes of protein domains: structural domain, functional domain and topological domain Functional domain: a region of a protein that exhibits a particular activity characteristic of the protein even when it is isolated from the rest of the protein A structural domain is a region ~40 or m ...
mtCLIC/CLIC4 a Chloride Channel Protein Participates in Apoptosis
mtCLIC/CLIC4 a Chloride Channel Protein Participates in Apoptosis

... state of degeneration, with completely degraded nuclei, ruptured membranes and deteriorating organelles. In apoptotic cells, however, the mitochondria appeared largely unchanged. To localize mtCLIC, we prepared cryosections of HACAT cells and labeled them with an affinitypurified antibody against C- ...
Expediting Purification of Cellular Proteins
Expediting Purification of Cellular Proteins

Rabbit anti-Occludin (N-term)
Rabbit anti-Occludin (N-term)

... Important Licensing Information - These products may be covered by one or more Limited Use Label Licenses (see the Invitrogen Catalog or our website, www.invitrogen.com). By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indic ...
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Magnesium transporter

This page links directly from the magnesium in biological systems page.Magnesium transporters are proteins that transport magnesium across the cell membrane. All forms of life require magnesium, yet the molecular mechanisms of Mg2+ uptake from the environment and the distribution of this vital element within the organism are only slowly being elucidated.In bacteria, Mg2+ is probably mainly supplied by the CorA protein and, where the CorA protein is absent, by the MgtE protein. In yeast the initial uptake is via the Alr1p and Alr2p proteins, but at this stage the only internal Mg2+ distributing protein identified is Mrs2p. Within the protozoa only one Mg2+ transporter (XntAp) has been identified. In metazoa, Mrs2p and MgtE homologues have been identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been identified along with another novel protein, AtMHX.
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