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CNS Antiparkinsonian Drugs
CNS Antiparkinsonian Drugs

... Affects handwriting – trailing off at ends of words More prominent at rest Aggravated by emotional stress or increased concentration “Pill rolling” – rotary motion of thumb and forefinger ...
States of Consciousness
States of Consciousness

... protected by a layer of capillaries called the blood-brain barrier. • The drugs that are small enough to pass through are called psychoactive drugs. ...
Clinical uses Chronic Hypertension
Clinical uses Chronic Hypertension

... appropriate drug should be selected from those that have documented efficacy for the disease • For example in heart failure clinical trials have demonstrated that at least three antagonists— metoprolol, bisoprolol, and carvedilol—are effective in reducing mortality associated with chronic heart fail ...
Psychoactive Medications
Psychoactive Medications

... Factors Affecting Time of Administration Absorption – Routes of administration are not therapeutically interchangeable (e.g. Valium is easily absorbed orally but slower and erratic when given IM) – Absorption can be slower when taken with food, milk or milk products – The elderly have more difficul ...
Neuroplasticity-induced changes in the brain
Neuroplasticity-induced changes in the brain

... Major depression Psychotic symptoms Distonia like Parkinson’s disease ...
Effect of H antihistamines upon the central nervous system
Effect of H antihistamines upon the central nervous system

... zone (composed of long association fibers among different areas) [15]. This represents an increase in blood perfusion demand for the conduction of visual discrimination and motor selection cognitive processes, i.e., it is more difficult to maintain attention or alertness under such circumstances (un ...
Larry Stein by Arvid Carlsson
Larry Stein by Arvid Carlsson

... can feel the reward, then the brain must be responsible for producing it. But the theories of positive reinforcement popular at that time were based in part on Freudian theory. Freud held the Victorian idea that reward is not so much excited by hedonically positive or pleasurable stimulation, but ra ...
NEUROSCIENCE AND OBESITY
NEUROSCIENCE AND OBESITY

... appetite. When they become defective, however, they lead to morbid obesity.  Recent research involving mice has revealed that activation of melanocortin-4 receptors in certain areas of the brain-the paraventricular hypothalamus and the amygdala-help reduce body fat by decreasing our desire to eat, ...
Section A: Answer four of the following five questions. Each question
Section A: Answer four of the following five questions. Each question

... 13. The activity of acetylcholine within the cholinergic synapse can be regulated: by antagonism of M1 receptors by endogenous pyruvate within the cholinergic synapse by acetylcholinesterase by carrier-mediated reuptake of acetylcholine into cholinergic nerve terminals by modulation of nicotinic Ach ...
Amphetamine Dependence - Redemption Psychiatry
Amphetamine Dependence - Redemption Psychiatry

... high risk. One of the differences between use and abuse is the reason why you take the drug. Taking medicine for reasons other than why they were prescribed is abuse. Taking more than the prescribed dose is also abuse. Drug addiction is a risk when these medicines are taken at doses higher than thos ...
Bioavailability
Bioavailability

... physiological, biochemical, microbiological, immunological and behavioral aspects of disease. Pharmacodynamics provides one of best opportunities for this correlation during the study of both the preclinical and the clinical medical sciences. ...
ALPRAZolam (al-pray-zoe-lam) - DavisPlus
ALPRAZolam (al-pray-zoe-lam) - DavisPlus

... doses. If a dose is missed, take within 1 hr; otherwise, skip the dose and return to regular schedule. If medication is less effective after a few weeks, check with health care professional; do not increase dose. Abrupt withdrawal may cause sweating, vomiting, muscle cramps, tremors, and seizures. M ...
Lecture. PSYCHOTROPIC DRUGS I. NEUROLEPTICS
Lecture. PSYCHOTROPIC DRUGS I. NEUROLEPTICS

... Corvalolum is mixture for oral administration, which is dosed by drops and contains ethylic ester of bromine-isovalerianic acid, 2% of phenobarbital, 3% of oil of menthe, sodium hydroxide, alcohol and water. It has sedative, spasmolytic and light hypnotic action and is used in neuroses, spasms of co ...
Phychiatric Drugs. Central Nervous System
Phychiatric Drugs. Central Nervous System

... for caffeine metabolism. In healthy adults, caffeine's halflife is approximately 3-4 hours. In women taking oral contraceptives this is increased to 5-10 hours, and in pregnant women the half-life is roughly 9-11 hours. Caffeine can accumulate in individuals with severe liver disease when its half-l ...
substance abuse - Molloy College
substance abuse - Molloy College

... attention and energy. Overdose of stimulants can cause anxiety, panic, tremors irregular heartbeat, restlessness, dangerously high body temp, and even heart attack. People who stop taking stimulants after some time may suffer from fatigue and depression. Toxic effect of high dose include: seizure, v ...
chapt22_lecture
chapt22_lecture

... The federal Food and Drug Administration (FDA) •Regulates the testing, manufacturing, content, and distribution of all drugs that are not from food •Evaluates safety or harmful effects of a drug to ensure the drug provides effective treatment ...
Yohimbine: Old Drug with New Interactions
Yohimbine: Old Drug with New Interactions

... increases sympathetic outflow to these neurons. A hypertensive crisis is possible. This potential interaction is based primarily on theoretical considerations, but it appears likely that it would occur. Yohimbine may also interact in patients receiving other MAOIs, such as furazolidone or methylene ...
Prodrugs and active metabolites among antidepressive
Prodrugs and active metabolites among antidepressive

... interest it is worth to mention that individual genetic differences in drug metabolism may significantly modify drug response (Sárosi et al., 2008). Active metabolite(s) of drugs may significantly modify clinical effect as these metabolites may have different pharmacokinetics than the parent compoun ...
Practical Psychopharmacology for the General Practitioner Valarie V
Practical Psychopharmacology for the General Practitioner Valarie V

... medications, if desired, to raise an animal’s threshold for performing the behavior or lower their anxiety level making it easier for them to learn. This complete program cannot be developed without a thorough history, an accurate diagnosis and time to explain the behavior modification protocol. If ...
Female Reproductive Cycle I
Female Reproductive Cycle I

... for the exchange of many substances including medications  Speed of exchange/transfer varies • Maternal and fetal blood flow • Molecular weight of the substance being ...
The Pharmacology of Parkinson`s Disease
The Pharmacology of Parkinson`s Disease

... 80% of patients show marked initial improvement (primarily in terms of resolution of muscle rigidity and bradykinesia).  20% show virtually normal motor function.  Over time, levodopa therapy becomes less effective ...
The Pharmacology of Parkinson`s Disease
The Pharmacology of Parkinson`s Disease

... 80% of patients show marked initial improvement (primarily in terms of resolution of muscle rigidity and bradykinesia).  20% show virtually normal motor function.  Over time, levodopa therapy becomes less effective ...
Guidelines and Treatment Updates in the Diagnosis and
Guidelines and Treatment Updates in the Diagnosis and

... • Work by increasing dopamine and norepinephrine signals to the brain by acting on dopamine and norepinephrine transporters and changing tonic and phasic dopamine releases – Increased dopamine signal leads to decrease extraneous noise – Increase norepinephrine signal leads to increased strength of s ...
Dugs
Dugs

... longer able to function normally. • The body then goes into withdrawal symptoms such as hallucinations, fevers, nausea (feeling sick) and shakes. • These are real, physical signs. ...
TERATOLOGY - Univerzita Karlova
TERATOLOGY - Univerzita Karlova

... Teratology Information Services are consulted by the medical profession and other health care professionals, some of them counsel lay people as well. Answers provided are specifically oriented towards individual patients. Detailed knowledge of dose, time of exposure, adverse effects on the mother re ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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