• - MSON2014
... junction, or muscle tissue Direct-Acting Antispasmodics – dantrolene (Dantrium); produce an antispasmodic effect at the level of the neuromuscular junction and skeletal muscle Treating Muscle Spasms directly @ the Muscle Tissue o Dantrolene relieves spasticity by interfering with the release of Ca ...
... junction, or muscle tissue Direct-Acting Antispasmodics – dantrolene (Dantrium); produce an antispasmodic effect at the level of the neuromuscular junction and skeletal muscle Treating Muscle Spasms directly @ the Muscle Tissue o Dantrolene relieves spasticity by interfering with the release of Ca ...
REVIEW ARTICLE
... 1. In context of malaria eradication there is a need for medicines that can be administered as a single dose which will allow direct monitoring and they should have activity against all exiting resistant strains of parasite. 2. New medicines are needed that kill gametocytes and thus prevent transmis ...
... 1. In context of malaria eradication there is a need for medicines that can be administered as a single dose which will allow direct monitoring and they should have activity against all exiting resistant strains of parasite. 2. New medicines are needed that kill gametocytes and thus prevent transmis ...
Therapeutic Drug Monitoring
... – Highly bound to tissues – What does this say about small changes in plasma digoxin concentration? ...
... – Highly bound to tissues – What does this say about small changes in plasma digoxin concentration? ...
Anxiety Disorders - University of Florida College of Dentistry
... weeks. An early sign of drug tolerance occurs when increased dosage is required. Symptoms of drug withdrawal include muscle aches, agitation, restlessness, insomnia, confusion, delirium, and, on rare occasions, grand mal seizures. Some patients may experience rebound anxiety after the drug treatment ...
... weeks. An early sign of drug tolerance occurs when increased dosage is required. Symptoms of drug withdrawal include muscle aches, agitation, restlessness, insomnia, confusion, delirium, and, on rare occasions, grand mal seizures. Some patients may experience rebound anxiety after the drug treatment ...
Key Points Handouts - Hansen Resource Development Inc
... Quality: Working on the best drug discovery and development ...
... Quality: Working on the best drug discovery and development ...
Bifunctional drugs for the treatment of asthma and chronic obstructive pulmonary disease
... These complementary activities have led to LABAs and LAMAs often being used together, particularly in the treatment of patients with COPD [21]. Additionally, it is recognised that these two classes of drug can provide better bronchodilation than using either class of drug alone (as described above), ...
... These complementary activities have led to LABAs and LAMAs often being used together, particularly in the treatment of patients with COPD [21]. Additionally, it is recognised that these two classes of drug can provide better bronchodilation than using either class of drug alone (as described above), ...
Pharmacology - Cardiovascular drugs II NCLEX MCQs
... Aldosterone antagonists compete with endogenous aldosterone and prevent sodium reabsorption in exchange for potassium elimination. Aldosterone antagonists work on inhibiting the action of aldosterone rather than creating an osmotic gradient. Aldosterone antagonist do not cause metabolic acidosis. Al ...
... Aldosterone antagonists compete with endogenous aldosterone and prevent sodium reabsorption in exchange for potassium elimination. Aldosterone antagonists work on inhibiting the action of aldosterone rather than creating an osmotic gradient. Aldosterone antagonist do not cause metabolic acidosis. Al ...
Noni Concentrate - Samento.com.ec Intro
... more ill, unable to perform daily home activities, with a 1½ year diagnosis of fibromyalgia, Chronic Fatigue Syndrome, depression and severe insomnia. She received various treatments that included: antibiotics, analgesics, vitamins and minerals, stimulants, sleeping pills (but no response to those). ...
... more ill, unable to perform daily home activities, with a 1½ year diagnosis of fibromyalgia, Chronic Fatigue Syndrome, depression and severe insomnia. She received various treatments that included: antibiotics, analgesics, vitamins and minerals, stimulants, sleeping pills (but no response to those). ...
Potassium Sparing Diuretics
... Synthetic steroids acts as competitive antagonist of adlosterone with slow onset of action. ...
... Synthetic steroids acts as competitive antagonist of adlosterone with slow onset of action. ...
E3 - Viktor`s Notes for the Neurosurgery Resident
... in 1940, PHENYTOIN was found to be effective drug - became major first-line antiepileptic drug for partial and secondarily generalized seizures. in 1990s, newer drugs with good efficacy, fewer toxic effects, better tolerability, and no need for blood level monitoring were developed. All antiepil ...
... in 1940, PHENYTOIN was found to be effective drug - became major first-line antiepileptic drug for partial and secondarily generalized seizures. in 1990s, newer drugs with good efficacy, fewer toxic effects, better tolerability, and no need for blood level monitoring were developed. All antiepil ...
Biological substrates of reward and aversion: A nucleus accumbens
... the rewarding effects of cocaine (Chartoff et al., 2006). The mechanisms by which diltiazem-induced alterations in Ca2þ influx affect reward are unknown. One possibility is that blockade of Ca2þ influx through voltage-operated L-type channels reduces the firing rate of neurons within the ventral NAc (C ...
... the rewarding effects of cocaine (Chartoff et al., 2006). The mechanisms by which diltiazem-induced alterations in Ca2þ influx affect reward are unknown. One possibility is that blockade of Ca2þ influx through voltage-operated L-type channels reduces the firing rate of neurons within the ventral NAc (C ...
Endocrinology 3a – Hyperthyroid Disorders
... These are use to treat hyperthyroidism conditions such as diffuse toxic goitre/Graves disease/exophthalmic goitre. They are also used in treatment before surgery or during thyroid irradiation with radioiodine. Mode of Action Their mechanism of action is not clearly understood but it is thought that ...
... These are use to treat hyperthyroidism conditions such as diffuse toxic goitre/Graves disease/exophthalmic goitre. They are also used in treatment before surgery or during thyroid irradiation with radioiodine. Mode of Action Their mechanism of action is not clearly understood but it is thought that ...
shands - UF Health Professionals
... it is not listed in the Formulary, because of its efficacy in the treatment of patients with resistant schizophrenia. The therapeutic choice among the atypical antipsychotics is generally based on the adverse drug effect profile, with the most common adverse effects influencing product selection. Zi ...
... it is not listed in the Formulary, because of its efficacy in the treatment of patients with resistant schizophrenia. The therapeutic choice among the atypical antipsychotics is generally based on the adverse drug effect profile, with the most common adverse effects influencing product selection. Zi ...
EU Core Safety Profile
... Pathological gambling, increased libido, and hypersexuality have been reported in patients treated with dopamine agonists including DOSTINEX. This has been generally reversible upon reduction of the dose or treatment discontinuation. 4.5 Interaction with other medicinal products and other forms of i ...
... Pathological gambling, increased libido, and hypersexuality have been reported in patients treated with dopamine agonists including DOSTINEX. This has been generally reversible upon reduction of the dose or treatment discontinuation. 4.5 Interaction with other medicinal products and other forms of i ...
The Nemertine Toxin Anabaseine and Its Derivative DMXBA (GTS-21): Chemical and Pharmacological Properties
... predators. Some of these compounds are also able to inhibit the settlement of barnacle larvae to marine surfaces and thus might be useful “antifouling” additives to marine paints. DMXB-Anabaseine (DMXBA), A Synthetic Anabaseine Derivative While anabaseine is a broad spectrum nicotinic agonist, a lar ...
... predators. Some of these compounds are also able to inhibit the settlement of barnacle larvae to marine surfaces and thus might be useful “antifouling” additives to marine paints. DMXB-Anabaseine (DMXBA), A Synthetic Anabaseine Derivative While anabaseine is a broad spectrum nicotinic agonist, a lar ...
Single Nucleotide Polymorphisms, Drug Metabolism and Untoward
... The multi-drug resistance family (ABCB1) is expressed in many normal tissues and has a role in the absorption and cellular excretion of toxic metabolites into bile and the intestinal lumen. Although 50 SNPs in the ABCB1 gene have been reported in different ethnic groups (Li et al.), only three (C343 ...
... The multi-drug resistance family (ABCB1) is expressed in many normal tissues and has a role in the absorption and cellular excretion of toxic metabolites into bile and the intestinal lumen. Although 50 SNPs in the ABCB1 gene have been reported in different ethnic groups (Li et al.), only three (C343 ...
Drugs and sex differences: a review of drugs relating to anaesthesia.
... lead to increased tissue load with possible toxic effects if the dose is not adjusted, and a prolonged half-life and increased serum/plasma concentrations on drug withdrawal. A further source of variability may be the physiological changes that occur during the menstrual cycle with fluctuations in w ...
... lead to increased tissue load with possible toxic effects if the dose is not adjusted, and a prolonged half-life and increased serum/plasma concentrations on drug withdrawal. A further source of variability may be the physiological changes that occur during the menstrual cycle with fluctuations in w ...
Naltrexone - Department of Psychiatry
... Opioid Pharmacology OPIOID: Any chemical compound with pharmacologic actions similar to those of morphine. The term “narcotic analgesic” is often used to refer to opioids. Sumerians (6000 years ago) called poppy “joy plants.” Morphine and codeine are alkaloids of the poppy plant, obtained as opium, ...
... Opioid Pharmacology OPIOID: Any chemical compound with pharmacologic actions similar to those of morphine. The term “narcotic analgesic” is often used to refer to opioids. Sumerians (6000 years ago) called poppy “joy plants.” Morphine and codeine are alkaloids of the poppy plant, obtained as opium, ...
Maropitant: Novel Antiemetic
... Substance P is involved in pain pathways, and NK-1 antagonists may have visceral analgesic effects in some species. For example, maropitant has an anestheticsparing effect during ovarian manipulation in dogs and cats undergoing ovariohysterectomy, when given at 1 mg/kg IV (followed by a 30 μg/kg/hr ...
... Substance P is involved in pain pathways, and NK-1 antagonists may have visceral analgesic effects in some species. For example, maropitant has an anestheticsparing effect during ovarian manipulation in dogs and cats undergoing ovariohysterectomy, when given at 1 mg/kg IV (followed by a 30 μg/kg/hr ...
“paco” cocaine
... from cocaine alkaloid, equal to some 300,000 threshold consumable doses of cocaine hydrochloride (using a threshold dose of 0.10 grams), or the equivalent of more than 5,400,000 threshold doses of paco…” Thursday, February 17, 2011, CIF, news service of the judicial branch. ...
... from cocaine alkaloid, equal to some 300,000 threshold consumable doses of cocaine hydrochloride (using a threshold dose of 0.10 grams), or the equivalent of more than 5,400,000 threshold doses of paco…” Thursday, February 17, 2011, CIF, news service of the judicial branch. ...
Ch. 18-Drugs used to Lower Lipids
... when build-up/blockage occurs in the heart’s arteries it causes coronary artery disease (CAD) CAD can lead to angina or MI CAD is leading cause of death in U.S. in men and women ...
... when build-up/blockage occurs in the heart’s arteries it causes coronary artery disease (CAD) CAD can lead to angina or MI CAD is leading cause of death in U.S. in men and women ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.