Vasoconstrictors: Myths and Realities
... vasoconstrictors in the histamine challenge model involved prevention of redness, with duration of action demonstrated at one to two hours after dosing for naphazoline, tetrahydrozoline and phenylephrine, but oxymetazoline was not tested.17 Studies today are still designed to establish the efficacy ...
... vasoconstrictors in the histamine challenge model involved prevention of redness, with duration of action demonstrated at one to two hours after dosing for naphazoline, tetrahydrozoline and phenylephrine, but oxymetazoline was not tested.17 Studies today are still designed to establish the efficacy ...
which postoperative analgesia for day-care surgery?
... the peak effect of morphine (eg. at 5-10 min) are slower than with fentanyl and meperidine (3-5 min). With injectable NSAIDs the peak effect is slow, occuring at 15-30 min [21]. Rectal administration usually provides faster, but more unreliable action compared with the oral route. Still faster, and ...
... the peak effect of morphine (eg. at 5-10 min) are slower than with fentanyl and meperidine (3-5 min). With injectable NSAIDs the peak effect is slow, occuring at 15-30 min [21]. Rectal administration usually provides faster, but more unreliable action compared with the oral route. Still faster, and ...
Palliative Care in Winnipeg
... Reduced potency of analgesic effects of opioids following repeated administration, i.e., increasing doses are necessary to produce pain relief Related to opioid receptor regulation Less common in pts with cancer pain Often reason pts “save” opioids until terminal phase Woodruff R, Palliative Medicin ...
... Reduced potency of analgesic effects of opioids following repeated administration, i.e., increasing doses are necessary to produce pain relief Related to opioid receptor regulation Less common in pts with cancer pain Often reason pts “save” opioids until terminal phase Woodruff R, Palliative Medicin ...
Dextromethorphan (DXM)
... little data available on prevalence and incidence. However, evidence suggests that it is not highly addictive. Users develop a tolerance, requiring larger doses to produce the same effect. This also increases the risk of side effects. It is possible that recreational users consider dextromethorphan ...
... little data available on prevalence and incidence. However, evidence suggests that it is not highly addictive. Users develop a tolerance, requiring larger doses to produce the same effect. This also increases the risk of side effects. It is possible that recreational users consider dextromethorphan ...
BETHANECHOL CHLORIDE TABLETS, USP 5 mg - Upsher
... parasympathetic nervous system. It increases the tone of the detrusor urinae muscle, usually producing a contraction sufficiently strong to initiate micturition and empty the bladder. It stimulates gastric motility, increases gastric tone and often restores impaired rhythmic peristalsis. Stimulation ...
... parasympathetic nervous system. It increases the tone of the detrusor urinae muscle, usually producing a contraction sufficiently strong to initiate micturition and empty the bladder. It stimulates gastric motility, increases gastric tone and often restores impaired rhythmic peristalsis. Stimulation ...
A Global Review of the Harm Reduction Response to Amphetamines
... methcathinone and cathinone, the four drugs discussed in this paper, stimulate the central nervous system and cause the rapid release of monoamine neurotransmitters.(2,3) They can produce feelings of energy, confidence, alertness, well-being, talkativeness and increased sex drive. They increase bloo ...
... methcathinone and cathinone, the four drugs discussed in this paper, stimulate the central nervous system and cause the rapid release of monoamine neurotransmitters.(2,3) They can produce feelings of energy, confidence, alertness, well-being, talkativeness and increased sex drive. They increase bloo ...
AVAPRO (irbesartan) tablets
... about 5000 subjects overall. This experience includes 1303 patients treated for over 6 months and 407 patients for 1 year or more. In placebo-controlled clinical trials, the following adverse reactions were reported in at least 1% of patients treated with irbesartan (n=1965) and at a higher incidenc ...
... about 5000 subjects overall. This experience includes 1303 patients treated for over 6 months and 407 patients for 1 year or more. In placebo-controlled clinical trials, the following adverse reactions were reported in at least 1% of patients treated with irbesartan (n=1965) and at a higher incidenc ...
OCULAR DRUG DELIVERY: TARGETING THE POSTERIOR
... powered by iontophoresis, can transfer high drug concentrations across ocular tissues to the posterior segment.13 The BioSeizer platform is a lipid-based technology that can carry a therapeutic agent and enable significantly prolonged retention time at the target site, thereby reducing the frequency ...
... powered by iontophoresis, can transfer high drug concentrations across ocular tissues to the posterior segment.13 The BioSeizer platform is a lipid-based technology that can carry a therapeutic agent and enable significantly prolonged retention time at the target site, thereby reducing the frequency ...
drug induced injury of the gi tract
... to be taking them until proved otherwise. Unfortunately, information about their use is seldom provided on patient pathology requisitions. Advertisers’ claims that their NSAIDs are safer than the other companies NSAIDs may or may not be correct and it is safe to assume that any NSAID may cause GI pr ...
... to be taking them until proved otherwise. Unfortunately, information about their use is seldom provided on patient pathology requisitions. Advertisers’ claims that their NSAIDs are safer than the other companies NSAIDs may or may not be correct and it is safe to assume that any NSAID may cause GI pr ...
Fruit Juice Interactions - Drug Interactions by Hansten and Horn
... amounts of grapefruit juice. In addition to being CYP3A4 substrates, each of these drugs has relatively low bioavailability due to high first-pass metabolism. For example, the bioavailability of lovastatin and simvastatin is about 5%, meaning that a dose of lovastatin or simvastatin is about 95% met ...
... amounts of grapefruit juice. In addition to being CYP3A4 substrates, each of these drugs has relatively low bioavailability due to high first-pass metabolism. For example, the bioavailability of lovastatin and simvastatin is about 5%, meaning that a dose of lovastatin or simvastatin is about 95% met ...
Antiepileptic Drugs
... a. Abnormal neuronal discharges from seizure focus (usually in cerebral cortex) and spread to other parts of the brain and produce abnormal movements, sensations or thoughts. b. May be due to excessive excitatory neurotransmitters mediated by glutamate: i. Activation of glutamate’s NMDA (N-methyl-D- ...
... a. Abnormal neuronal discharges from seizure focus (usually in cerebral cortex) and spread to other parts of the brain and produce abnormal movements, sensations or thoughts. b. May be due to excessive excitatory neurotransmitters mediated by glutamate: i. Activation of glutamate’s NMDA (N-methyl-D- ...
a study of prescription pattern of non steroidal anti
... ORIGINAL ARTICLE Prevalence of prescriptions containing parenteral (IM route) preparations of NSAIDs in this study is 9%, which is almost similar when compared to study conducted in Manipal where parenteral preparation of NSAID prevalence was 8.6%16. In present study Fever was the commonest indicat ...
... ORIGINAL ARTICLE Prevalence of prescriptions containing parenteral (IM route) preparations of NSAIDs in this study is 9%, which is almost similar when compared to study conducted in Manipal where parenteral preparation of NSAID prevalence was 8.6%16. In present study Fever was the commonest indicat ...
Pain Scenarios - mededcoventry.com
... • Pain is an individual, multifactorial experience influenced by culture, previous experience, mood and ability to cope • Successful acute pain management involves teamwork • Regular assessment of pain = improved outcomes • Uncontrolled or unexpected pain requires reassessment of diagnosis / reinves ...
... • Pain is an individual, multifactorial experience influenced by culture, previous experience, mood and ability to cope • Successful acute pain management involves teamwork • Regular assessment of pain = improved outcomes • Uncontrolled or unexpected pain requires reassessment of diagnosis / reinves ...
HOW TO SELECT MIGRAINE HOW TO SELECT MIGRAINE PREVENTIVES Financial Disclosure
... Blood studies ...
... Blood studies ...
O A RIGINAL
... Background: Diabetes is the most common metabolic disease in humans, which can lead to kidney damage; Azathioprine is widely used in the treatment of other autoimmune diseases, cancer, and organ transplantation. In this study, the effect of azathioprine on renal tissue and serum markers of insulin r ...
... Background: Diabetes is the most common metabolic disease in humans, which can lead to kidney damage; Azathioprine is widely used in the treatment of other autoimmune diseases, cancer, and organ transplantation. In this study, the effect of azathioprine on renal tissue and serum markers of insulin r ...
Abstract Book - cannabis medicine
... DEPRESSION. Cannabinoids have been thought to relieve depression, but it is unclear whether or not these observations are due to agonist or antagonist effects on the CB1 receptor. Experiments were conducted to determine whether or not the specific antagonist SR141716 or the THC extract would act lik ...
... DEPRESSION. Cannabinoids have been thought to relieve depression, but it is unclear whether or not these observations are due to agonist or antagonist effects on the CB1 receptor. Experiments were conducted to determine whether or not the specific antagonist SR141716 or the THC extract would act lik ...
HIVART_9 - I-Tech
... offending agent with a drug which doesn’t cause the specific side effect. If there is a life threatening toxicity, stop all drugs until patient’s condition is stabilized In case of treatment failure, first check patient’s adherence and then change all 3 drugs ...
... offending agent with a drug which doesn’t cause the specific side effect. If there is a life threatening toxicity, stop all drugs until patient’s condition is stabilized In case of treatment failure, first check patient’s adherence and then change all 3 drugs ...
6 Anxiety disorders and substance use
... occurring in the absence of a specific danger or real threat. According to the National Survey of Mental Health and Wellbeing, anxiety disorders are the most common form of mental disorder in the population with a one-year prevalence of 9.7% in Australian adults(68). The fear and worry associated wi ...
... occurring in the absence of a specific danger or real threat. According to the National Survey of Mental Health and Wellbeing, anxiety disorders are the most common form of mental disorder in the population with a one-year prevalence of 9.7% in Australian adults(68). The fear and worry associated wi ...
Antibiotics - Lyme Disease Association of Southeastern PA
... Antibiotics are powerful drugs Fact: Compared to most drugs, antibiotics are mild, with minimal side-effects (especially those used to treat Lyme disease) ...
... Antibiotics are powerful drugs Fact: Compared to most drugs, antibiotics are mild, with minimal side-effects (especially those used to treat Lyme disease) ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.